Map4k5 (mitogen-activated protein kinase kinase kinase kinase 5) - Rat Genome Database

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Gene: Map4k5 (mitogen-activated protein kinase kinase kinase kinase 5) Rattus norvegicus
Analyze
Symbol: Map4k5
Name: mitogen-activated protein kinase kinase kinase kinase 5
RGD ID: 1562028
Description: Predicted to enable ATP binding activity and MAP kinase kinase kinase kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human MAP4K5 (mitogen-activated protein kinase kinase kinase kinase 5); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC503027; RGD1562028; similar to mitogen-activated protein kinase kinase kinase kinase 5 isoform 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8694,020,079 - 94,112,943 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl694,020,079 - 94,112,943 (-)EnsemblGRCr8
mRatBN7.2688,284,087 - 88,377,118 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,284,094 - 88,376,799 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx688,682,790 - 88,775,999 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0688,982,254 - 89,075,463 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0688,421,994 - 88,514,988 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,136,242 - 92,229,578 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,136,992 - 92,229,260 (-)Ensemblrn6Rnor6.0
Rnor_5.06101,585,538 - 101,678,657 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4691,885,447 - 91,978,735 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera686,779,691 - 86,871,808 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytosol  (IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9038372  


Genomics

Comparative Map Data
Map4k5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8694,020,079 - 94,112,943 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl694,020,079 - 94,112,943 (-)EnsemblGRCr8
mRatBN7.2688,284,087 - 88,377,118 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,284,094 - 88,376,799 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx688,682,790 - 88,775,999 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0688,982,254 - 89,075,463 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0688,421,994 - 88,514,988 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,136,242 - 92,229,578 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,136,992 - 92,229,260 (-)Ensemblrn6Rnor6.0
Rnor_5.06101,585,538 - 101,678,657 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4691,885,447 - 91,978,735 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera686,779,691 - 86,871,808 (-)NCBICelera
Cytogenetic Map6q24NCBI
MAP4K5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381450,418,521 - 50,561,126 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1450,417,845 - 50,561,126 (-)Ensemblhg38GRCh38
GRCh371450,885,239 - 50,999,287 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361449,954,993 - 50,069,126 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341449,954,992 - 50,069,126NCBI
Celera1430,752,350 - 30,866,424 (-)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1431,010,380 - 31,124,579 (-)NCBIHuRef
CHM1_11450,823,813 - 50,937,937 (-)NCBICHM1_1
T2T-CHM13v2.01444,624,744 - 44,767,297 (-)NCBIT2T-CHM13v2.0
Map4k5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391269,850,531 - 69,939,937 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1269,850,524 - 69,939,974 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381269,803,757 - 69,893,163 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1269,803,750 - 69,893,200 (-)Ensemblmm10GRCm38
MGSCv371270,904,744 - 70,994,150 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361270,722,362 - 70,811,768 (-)NCBIMGSCv36mm8
Celera1270,899,904 - 70,995,304 (-)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1228.94NCBI
Map4k5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540912,315,321 - 12,396,136 (+)Ensembl
ChiLan1.0NW_00495540912,319,806 - 12,396,136 (+)NCBIChiLan1.0ChiLan1.0
MAP4K5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21551,554,822 - 51,671,662 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11450,771,324 - 50,888,105 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01431,008,177 - 31,122,127 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11449,311,733 - 49,425,529 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1449,311,733 - 49,425,520 (-)EnsemblpanPan2panpan1.1
MAP4K5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1826,851,143 - 26,960,144 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl826,852,689 - 26,959,980 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha826,604,503 - 26,713,962 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0827,028,723 - 27,137,853 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl827,028,741 - 27,137,036 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1826,683,589 - 26,792,878 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0826,756,060 - 26,866,857 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0827,074,892 - 27,184,205 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Map4k5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864059,032,682 - 59,138,318 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649515,053,275 - 15,159,011 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649515,053,275 - 15,159,011 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAP4K5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1180,164,458 - 180,299,496 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11180,164,427 - 180,299,491 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21200,523,478 - 200,568,182 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAP4K5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12427,496,269 - 27,604,726 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2427,493,322 - 27,604,295 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605315,814,474 - 15,921,001 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Map4k5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473118,362,856 - 18,460,761 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Map4k5
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1783,470,972 - 83,563,479 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Map4k5
585 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:437
Count of miRNA genes:253
Interacting mature miRNAs:312
Transcripts:ENSRNOT00000006705
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006705   ⟹   ENSRNOP00000006705
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,020,079 - 94,112,943 (-)Ensembl
mRatBN7.2 Ensembl688,284,094 - 88,376,799 (-)Ensembl
Rnor_6.0 Ensembl692,136,992 - 92,229,260 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105643   ⟹   ENSRNOP00000091112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,020,079 - 94,112,943 (-)Ensembl
mRatBN7.2 Ensembl688,284,094 - 88,376,799 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106217   ⟹   ENSRNOP00000092920
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,020,079 - 94,112,943 (-)Ensembl
mRatBN7.2 Ensembl688,284,094 - 88,376,799 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000154426   ⟹   ENSRNOP00000104623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,020,079 - 94,112,943 (-)Ensembl
RefSeq Acc Id: NM_001192016   ⟹   NP_001178945
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8694,020,079 - 94,112,943 (-)NCBI
mRatBN7.2688,284,087 - 88,376,958 (-)NCBI
Rnor_6.0692,136,982 - 92,229,260 (-)NCBI
Rnor_5.06101,585,538 - 101,678,657 (-)NCBI
Celera686,779,691 - 86,871,808 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006240180   ⟹   XP_006240242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8694,020,086 - 94,112,724 (-)NCBI
mRatBN7.2688,284,094 - 88,377,118 (-)NCBI
Rnor_6.0692,136,242 - 92,229,578 (-)NCBI
Rnor_5.06101,585,538 - 101,678,657 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178945 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240242 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM03533 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006705
  ENSRNOP00000006705.6
  ENSRNOP00000091112.1
  ENSRNOP00000092920
  ENSRNOP00000092920.1
  ENSRNOP00000104623.1
RefSeq Acc Id: NP_001178945   ⟸   NM_001192016
- UniProtKB: D3ZHL6 (UniProtKB/TrEMBL),   A0A8I6AJ75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240242   ⟸   XM_006240180
- Peptide Label: isoform X1
- UniProtKB: A6HBX7 (UniProtKB/TrEMBL),   A0A8I6AJ75 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006705   ⟸   ENSRNOT00000006705
Ensembl Acc Id: ENSRNOP00000092920   ⟸   ENSRNOT00000106217
Ensembl Acc Id: ENSRNOP00000091112   ⟸   ENSRNOT00000105643
Ensembl Acc Id: ENSRNOP00000104623   ⟸   ENSRNOT00000154426
Protein Domains
CNH   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZHL6-F1-model_v2 AlphaFold D3ZHL6 1-846 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562028 AgrOrtholog
BioCyc Gene G2FUF-37221 BioCyc
Ensembl Genes ENSRNOG00000004923 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006705 ENTREZGENE
  ENSRNOT00000006705.7 UniProtKB/TrEMBL
  ENSRNOT00000105643.2 UniProtKB/TrEMBL
  ENSRNOT00000106217 ENTREZGENE
  ENSRNOT00000106217.2 UniProtKB/TrEMBL
  ENSRNOT00000154426.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Citron UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  MAPKKKK UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  STE20/SPS1-PAK UniProtKB/TrEMBL
KEGG Report rno:503027 UniProtKB/TrEMBL
NCBI Gene 503027 ENTREZGENE
PANTHER MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 5 UniProtKB/TrEMBL
  STERILE20-LIKE KINASE, ISOFORM B-RELATED UniProtKB/TrEMBL
Pfam CNH UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PhenoGen Map4k5 PhenoGen
PIRSF MAPKKKK UniProtKB/TrEMBL
PROSITE CNH UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004923 RatGTEx
SMART CNH UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A8I6AJ75 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJD3_RAT UniProtKB/TrEMBL
  A0ABK0L4Q1_RAT UniProtKB/TrEMBL
  A6HBX7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZHL6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-29 Map4k5  mitogen-activated protein kinase kinase kinase kinase 5  RGD1562028_predicted  similar to mitogen-activated protein kinase kinase kinase kinase 5 isoform 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562028_predicted  similar to mitogen-activated protein kinase kinase kinase kinase 5 isoform 2 (predicted)  LOC503027  similar to mitogen-activated protein kinase kinase kinase kinase 5 isoform 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC503027  similar to mitogen-activated protein kinase kinase kinase kinase 5 isoform 2      Symbol and Name status set to provisional 70820 PROVISIONAL