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Gene: Plch1 (phospholipase C, eta 1) Rattus norvegicus

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Symbol:

Plch1

Name:

phospholipase C, eta 1

RGD ID:

1561991

Description:

Predicted to enable calcium-dependent phospholipase C activity and phosphatidylinositol-4,5-bisphosphate phospholipase C activity. Predicted to be involved in phosphatidylinositol metabolic process; phosphatidylinositol-mediated signaling; and release of sequestered calcium ion into cytosol. Predicted to be located in cytosol and membrane. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in holoprosencephaly. Orthologous to human PLCH1 (phospholipase C eta 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase eta-1; LOC310463; phospholipase C-like 3; Plcl3; RGD1561991; similar to Hypothetical protein MGC57096

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PLCH1 (phospholipase C eta 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Plch1 (phospholipase C, eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Plch1 (phospholipase C eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PLCH1 (phospholipase C eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PLCH1 (phospholipase C eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Plch1 (phospholipase C eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PLCH1 (phospholipase C eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PLCH1 (phospholipase C eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Plch1 (phospholipase C eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Plch1 (phospholipase C eta 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PLCH1 (phospholipase C eta 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Plch1 (phospholipase C, eta 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	plch1 (phospholipase C, eta 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	plch1 (phospholipase C, eta 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PLC1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	PLC1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	plch1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	150,298,547 - 150,514,120 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	150,299,075 - 150,464,019 (-)	Ensembl				GRCr8
mRatBN7.2	2	148,148,908 - 148,363,616 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	148,148,921 - 148,364,097 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	154,861,345 - 154,959,674 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	152,910,789 - 153,009,122 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	147,543,478 - 147,641,810 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	154,256,382 - 154,468,166 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	154,256,380 - 154,418,920 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	173,640,220 - 173,849,566 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	153,467,156 - 153,562,651 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	142,435,231 - 142,522,875 (-)	NCBI		Celera
Cytogenetic Map	2	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Holoprosencephaly 14 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

calcitriol (ISO)

cytarabine (ISO)

dibutyl phthalate (EXP)

dorsomorphin (ISO)

entinostat (ISO)

formaldehyde (ISO)

FR900359 (ISO)

fulvestrant (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (ISO)

okadaic acid (ISO)

ozone (ISO)

paraquat (EXP)

pentanal (ISO)

permethrin (ISO)

progesterone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

streptozocin (ISO)

temozolomide (ISO)

testosterone (EXP,ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triclosan (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zearalenone (ISO)

zinc sulfate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular signal transduction (IEA)

lipid catabolic process (IEA)

lipid metabolic process (IEA)

phosphatidylinositol metabolic process (IBA)

phosphatidylinositol-mediated signaling (IBA,ISO)

release of sequestered calcium ion into cytosol (IBA)

signal transduction (IEA)

Cellular Component

cytoplasm (IBA,IEA,ISO)

cytosol (IEA,ISO)

membrane (IEA,ISO)

Molecular Function

calcium ion binding (IEA)

calcium-dependent phospholipase C activity (IEA,ISO)

hydrolase activity (IEA)

metal ion binding (IEA)

phosphatidylinositol-4,5-bisphosphate phospholipase C activity (IBA,IEA)

phosphoric diester hydrolase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15702972	PMID:31904090

Genomics

Comparative Map Data

Plch1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	150,298,547 - 150,514,120 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	150,299,075 - 150,464,019 (-)	Ensembl				GRCr8
mRatBN7.2	2	148,148,908 - 148,363,616 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	148,148,921 - 148,364,097 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	154,861,345 - 154,959,674 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	152,910,789 - 153,009,122 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	147,543,478 - 147,641,810 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	154,256,382 - 154,468,166 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	154,256,380 - 154,418,920 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	173,640,220 - 173,849,566 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	153,467,156 - 153,562,651 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	142,435,231 - 142,522,875 (-)	NCBI		Celera
Cytogenetic Map	2	q31	NCBI

PLCH1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	155,450,934 - 155,745,071 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	155,375,580 - 155,745,085 (-)	Ensembl			hg38	GRCh38
GRCh37	3	155,197,670 - 155,462,860 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	156,680,365 - 156,796,861 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	3	156,680,372 - 156,796,869	NCBI
Celera	3	153,618,259 - 153,842,073 (-)	NCBI		Celera
Cytogenetic Map	3	q25.31	NCBI
HuRef	3	152,592,070 - 152,816,187 (-)	NCBI		HuRef
CHM1_1	3	155,160,735 - 155,385,162 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	158,220,392 - 158,518,944 (-)	NCBI		T2T-CHM13v2.0

Plch1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	63,603,620 - 63,806,929 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	63,603,655 - 63,806,893 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	63,696,199 - 63,899,503 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	63,696,234 - 63,899,472 (-)	Ensembl			mm10	GRCm38
MGSCv37	3	63,500,156 - 63,654,913 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	63,784,166 - 63,938,968 (-)	NCBI		MGSCv36	mm8
Celera	3	63,363,083 - 63,521,241 (-)	NCBI		Celera
Cytogenetic Map	3	E1	NCBI
cM Map	3	30.08	NCBI

Plch1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955448	6,588,834 - 6,815,087 (-)	Ensembl
ChiLan1.0	NW_004955448	6,588,885 - 6,815,087 (-)	NCBI	ChiLan1.0	ChiLan1.0

PLCH1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	153,389,975 - 153,659,937 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	153,394,705 - 153,664,656 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	152,530,928 - 152,800,963 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	160,484,462 - 160,853,113 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	160,583,085 - 160,784,611 (-)	Ensembl			panPan2	panpan1.1

PLCH1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	49,280,314 - 49,483,210 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	49,281,620 - 49,450,050 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	49,155,971 - 49,359,036 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	49,915,081 - 50,116,886 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	49,914,938 - 50,055,473 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	49,500,267 - 49,704,229 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	49,549,504 - 49,752,859 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	49,834,268 - 50,037,303 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Plch1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	86,701,070 - 86,925,249 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936519	2,808,671 - 2,966,700 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936519	2,808,703 - 2,998,546 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLCH1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	95,406,823 - 95,643,193 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	95,402,015 - 95,644,647 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	103,429,398 - 103,665,855 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLCH1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	35,010,862 - 35,272,347 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666041	7,651,589 - 7,907,512 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plch1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	33,047,933 - 33,363,939 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624730	33,048,074 - 33,363,919 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Plch1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	91,342,012 - 91,537,700 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Plch1
1487 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	110
Count of miRNA genes:	95
Interacting mature miRNAs:	99
Transcripts:	ENSRNOT00000057724
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293671	Bss44	Bone structure and strength QTL 44	10.97	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	2	105628029	150628029	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1358360	Sradr2	Stress Responsive Adrenal Weight QTL 2	10.24		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	2	124103798	154505346	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	138595962	205135428	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	124537199	209621565	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
10043136	Iddm54	Insulin dependent diabetes mellitus QTL 54	3.4	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	145807215	190807215	Rat
10043139	Iddm55	Insulin dependent diabetes mellitus QTL 55	3.1	0.0001	blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	2	150313808	195313808	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
1359030	Bp277	Blood pressure QTL 277			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	143565208	188565208	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
1581502	Esta3	Estrogen-induced thymic atrophy QTL 3			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	139067258	192287892	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
1582257	Gluco21	Glucose level QTL 21	3.1	0.0035	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	120039407	159440891	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	159440891	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	144882354	205135428	Rat
8662836	Vetf8	Vascular elastic tissue fragility QTL 8	0.66		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	106869825	151869825	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	27148557	159440760	Rat
5135226	Leukc2	Leukocyte quantity QTL 2			eosinophil quantity (VT:0002602)	blood eosinophil count (CMO:0000033)	2	120039407	151869825	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1359022	Ppulsi1	Prepulse inhibition QTL 1	3.63		prepulse inhibition trait (VT:0003088)	acoustic startle response measurement (CMO:0001519)	2	139067258	184067258	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	27148328	159440891	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	143746578	205135428	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
1598805	Memor8	Memory QTL 8	3		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	150096616	195096616	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	145306936	212705578	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	113746222	205135428	Rat
61401	Niddm2	Non-insulin dependent diabetes mellitus QTL 2	4.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	147287892	192287892	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
738007	Anxrr7	Anxiety related response QTL 7	4.4		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	2	120339555	165339555	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	117415288	205135428	Rat
2293835	Kiddil5	Kidney dilation QTL 5	3.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	159440891	Rat
631520	Bp73	Blood pressure QTL 73		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149806826	170653323	Rat
1598833	Bp295	Blood pressure QTL 295	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	150096616	195096616	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
1558653	Prcr1	Prostate cancer resistance QTL 1	5		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	2	114440891	159440891	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
2293843	Kiddil6	Kidney dilation QTL 6	3.1		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	44537979	184731399	Rat
1354594	Despr10	Despair related QTL 10		2e-06	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	2	116804572	161804572	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat
6903312	Bw112	Body weight QTL 112	3.2	0.0013	body mass (VT:0001259)	body weight (CMO:0000012)	2	145807215	173074435	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	30219200	171802126	Rat

Markers in Region

D2Got88

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	148,176,358 - 148,176,503 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	154,283,645 - 154,283,789	NCBI	Rnor6.0
Rnor_5.0	2	173,667,483 - 173,667,627	UniSTS	Rnor5.0
RGSC_v3.4	2	153,494,426 - 153,494,571	RGD	RGSC3.4
RGSC_v3.4	2	153,494,427 - 153,494,571	UniSTS	RGSC3.4
Celera	2	142,462,125 - 142,462,255	UniSTS
RGSC_v3.1	2	153,444,390 - 153,444,534	RGD
RH 3.4 Map	2	947.9	RGD
RH 3.4 Map	2	947.9	UniSTS
Cytogenetic Map	2	q31	UniSTS

AA892150

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	148,361,971 - 148,362,185 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	154,466,534 - 154,466,747	NCBI	Rnor6.0
Rnor_5.0	2	173,850,372 - 173,850,585	UniSTS	Rnor5.0
RGSC_v3.4	2	153,687,648 - 153,687,861	UniSTS	RGSC3.4
Celera	2	142,644,169 - 142,644,382	UniSTS
RH 3.4 Map	2	946.7	UniSTS
Cytogenetic Map	2	q31	UniSTS

AA892150

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	148,362,163 - 148,362,265 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	154,466,726 - 154,466,827	NCBI	Rnor6.0
Rnor_5.0	2	173,850,564 - 173,850,665	UniSTS	Rnor5.0
RGSC_v3.4	2	153,687,840 - 153,687,941	UniSTS	RGSC3.4
Celera	2	142,644,361 - 142,644,462	UniSTS
RH 3.4 Map	2	946.7	UniSTS
Cytogenetic Map	2	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	8	47	163	62	61	30	65	30	6	275	141	9	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191707	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102284	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281792	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281793	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281795	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281796	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281798	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000057724 ⟹ ENSRNOP00000054535

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	148,150,100 - 148,364,097 (-)	Ensembl
Rnor_6.0 Ensembl	2	154,256,392 - 154,334,356 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076165 ⟹ ENSRNOP00000068291

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	150,302,114 - 150,464,019 (-)	Ensembl
mRatBN7.2 Ensembl	2	148,150,100 - 148,314,359 (-)	Ensembl
Rnor_6.0 Ensembl	2	154,256,380 - 154,418,676 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076274 ⟹ ENSRNOP00000068287

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	148,148,921 - 148,314,359 (-)	Ensembl
Rnor_6.0 Ensembl	2	154,256,380 - 154,418,629 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000076326 ⟹ ENSRNOP00000068040

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	150,299,075 - 150,464,019 (-)	Ensembl
mRatBN7.2 Ensembl	2	148,149,436 - 148,314,359 (-)	Ensembl
Rnor_6.0 Ensembl	2	154,256,393 - 154,418,920 (-)	Ensembl

RefSeq Acc Id:

NM_001191707 ⟹ NP_001178636

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,299,075 - 150,387,798 (-)	NCBI
mRatBN7.2	2	148,149,436 - 148,238,134 (-)	NCBI
Rnor_6.0	2	154,256,908 - 154,343,671 (-)	NCBI
Rnor_5.0	2	173,640,220 - 173,849,566 (-)	NCBI
Celera	2	142,435,231 - 142,522,875 (-)	NCBI

Sequence:

show sequence

ATGAGTGTAATGCAGTCCGGGACACAGATGATCAAGCTGAAGCGTGGCACCAAAGGTCTCGTTC
GCCTCTTTTACCTGGATGAACACCGGACCCGCCTTCGATGGCGACCCTCTAGGAAGAGTGAGAA
GGCAAAAATACTTATTGATTCCATCTACAAAGTCACCGAGGGCAGGCAGTCTGAAATTTTCCAC
AGACAGGCTGAGGGGAACTTTGATCCCAGCTGCTGCTTTACCATCTACCATGGCAACCACATGG
AGTCCCTGGACCTCATTACCTCCAACCCAGAGGAGGCACGCACCTGGATCACGGGCCTCAAGTA
TCTGATGGCTGGCATCAGTGATGAAGACTCCCTTGCCAAGAGGCAAAGGACCCATGACCAATGG
GTGAAGCAGACCTTTGAGGAGGCTGATAAGAATGGTGATGGCTTATTGAATATTGAAGAGATTC
ACCAGCTGATGCATAAACTAAATGTCAATCTGCCTCGAAGAAAAGTCAGGCAAATGTTTCAGGA
AGCGGACACAGATGAGAATCAGGGGACCTTGACATTTGAAGAGTTCTGCGTTTTTTACAAAATG
ATGTCATTGAGACGAGACCTCTATTTGCTGCTCTTGAGCTACAGTGACAAGAAAGACCACCTTA
CTGTGGAGGAGCTAGCTCAGTTCTTGAAGGTGGAACAAAAGATGAGTAATGTCACACTGGACTA
TTGTCTGGACGTCATAAAGAAGTTCGAAGTTTCTGAAGAAAACAAAGTGAAAAACGTCCTCGGT
ATAGAAGGTTTCACGAACTTCATGCGTAGCCCTGCTTGTGATGTATTTAACCCTTTGCACCATG
AAGTATACCAAGACATGGATCAGCCTCTCTGCAATTACTACATTGCTTCTTCTCATAACACATA
CCTGACTGGGGACCAGCTCCTTTCTCAATCCAAAGTGGACATGTATGCACGGGTGCTACAAGAG
GGATGTCGATGCGTGGAAGTTGACTGTTGGGATGGCCCAGATGGAGAGCCAGTGGTCCACCATG
GTTATACTCTCACTTCAAAAATTCTCTTCAAAGATGTTGTGGAGACCATCAACAAGCATGCATT
TGTTAAAAATGAGTTTCCCGTTATACTGTCCATTGAGAACCACTGCAGTATTCAGCAGCAGAGG
AAGATTGCTCAGTACCTGAAAGGAATATTCCAGGACAAACTGGACCTGTCATCTGTAGACACAG
GAGAGTGCAGGCAGCTTCCAAGCCCTCAGAGTCTGAAAGGCAAAATCCTGGTGAAGGGCAAGAA
GTTGCCATATCACCTTGGGGATGATGCAGAGGAAGGAGAAGTGTCCGATGAGGACAGTGCAGAT
GAAATTGAAGATGAATGCAAGTTCAAGCTGCATTATAGTAACGGGACCACTGAGCACCAGGTAG
AATCTTTCATACGGAAAAAGCTGGACTCACTGTTGAAGGAGTCTCAGATTCGAGACAAGGAAGA
CCCAGACAGTTTCACAGTGAGGGCGTTACTCAAGGCTACACATGAAGGCTTAAATGCACACCTG
AAGCAGAACCTGGATGTGAAGGAAAGTGGAAAGAAGTCCCATGGGCGATCCCTGATGGCCAACT
TTGGGAAACACAAGAAAACTCCAAAATCACGTTCTAAATCCTATAGTACTGATGATGAGGAAGA
TACACTACAGAATCCTGGCAAGGAGGGAGGCCAGCTGTACAGGCTGGGCCGCCGAAGGAGAACC
ATGAAACTCTGCAGAGAGCTCTCGGACTTGGTGGTGTACACAAACTCTGTGGCAGCCCAGGATA
TTGTGGATGATGGGACCACAGGGAATGTGTTGTCCTTCAGTGAAACAAGAGCACATCAAGTGGT
TCAGCAGAAGTCAGAGCAGTTCATGATCTACAACCAAAAACAGCTCACGAGGATTTACCCCTCT
GCCTACCGCATCGATTCCAGTAACTTCAACCCTCTGCCCTACTGGAATGCGGGCTGCCAGCTAG
TGGCTCTGAACTACCAGTCTGAAGGGCGAATGATGCAGATAAATCGAGCAAAATTCAAAGCAAA
CGGCAACTGTGGCTACATTCTCAAGCCCCAGCAAATGTGCAAAGGAACATTCAACCCTTTGTCT
GGTGACCCACTTCCTGCCAACCCCAAAAAACAGCTCATACTGAAAGTGATCAGTGGACAGCAAC
TCCCCAAACCCCCTGACTCTATGTTTGGAGACCGAGGCGAGATCATTGACCCTTTTGTTGAAGT
TGAAATTATTGGGCTTCCTGTAGACTGTTGCAAGGACCAAACTCGTGTGGTGGATGACAATGGA
TTTAACCCTGTGTGGGAAGAAACCCTAACTTTTACAGTTCACATGCCAGAAATAGCTTTGGTTC
GATTTCTTGTGTGGGATCATGATCCTATCGGAAGAGACTTTGTGGGACAACGGACCGTGACCTT
CAGCAGCCTCGTGCCTGGCTACCGGCATGTCTACCTGGAAGGCCTCACAGAAGCGTCTATTTTC
GTTCACATAACAATCAATGAGATCTTTGGAAAGAACAGACAGCTCCAAGGCTTGAAGGGACTGT
TCAATAAGAATCCCAGGCACGGTTCTTCAGAAAATAACTCCCATTATGTTCGGAAGCGATCAAT
TGGAGATAGAATTCTGCGACGTACAGCCAGTGCTCCAGCCAAAGGCAGGAAAAAGAGCAAAGTG
GGCTTCCAAGAAATGGTTGAGATAAAAGATTCTGTCTGTGAGGCTACAAGAGATCAAGATGGTG
TCCTGAGGAGGACCACACGGAGTCTGCAACTGCGCCCTGTCTCTATGCCTGTTGACAAGAACCT
TCTGGGGGCTTTGTCACTGCCTATCTCTGAAGCAGCAAAAAACACAGATGGAAAAGAAAACTAT
CTGGCAGAGGACAAGGATGATGGAAGAAAGGGGCCAGCAACTATAAAAGACCCACATTTTTCCA
ATTTCAACAAAAAGTTATCCTCCTCCTCCAGTGCCCTCCTCCACAAAGATGCCAAAAACCAAGG
GCCAACAGCCAGTGTATCAAACCCAGAACAGTGTGGAGGACTAGGTTTAAAGAGTGGGAGAATC
AAACCACATATGACAAATGATTGCCAGGAAAACCGCAGTCCCCAAAACTTCCTCTCTCCAAGGA
AGCATTTGGCACTTGATCCCGCAACCAAGGGACTGCAAGATCTGCATGGAATGAGAACTGATGA
AAAGGAGCAGGAGCGTGCCAAGGGCTTTGTGGGAAGGAAAAGCACGCAGAGCGAAAGTGTTCTT
TCTCAAAGTTCTCTGGAGGTGGAGAATCTGGAAGGCAGCAAGGCCAAGGGCAGAGCTGCAACGT
CCTTTTCTCTCTCCGATGTCTCTGCACTCTGTTCTGACATTCCTGATTTGCATTCAACTGCCAT
TCTGCAGGACACTGAAATTTCCGATCTCATTAATGATGTGACTTTAACAAATGCAAATGAGTCG
GGCAGTTCCATCTCAGCACTGATCGGCCAGTTTGAAGAGAGCAACCATCGGGCTAACGTTGCCG
TGGTTTCTCGTCTCCTTAGCACCAGTGGGACATCAGAAGGTGTTGCTTTGCCAGTCGCGTTGGG
CCTACAAACACCCATCAAGAATGGCTTTTCCCAGGGGAAGCACAAGGCCTCCTTCTTGTGCTCA
TCTCCTGAGTTGAACAAGCCCTCTAGTGCGGAAACCACCAAACTGGCAAATAACACAGTTGCCT
GTGGAGTGATTGGCTCTCCCATCTCTACACCAAAGCCAGGTGATGACGCTTCTGATAAAGCCAA
GACAAGGGTCACGGAAGACAACCTGCCTGATTCCCCTGATGCTTTTCCTGGCCAGTTTCCCCAA
AGCCCCACCCACGGAGAGGACCATAGGCAAGTGATGAGCAGCCCTGCTCTCTCCATGCCGTTGG
CCATGGAAGATACAACAGCTGACCCCGCTCTCTGTATAAATTCTGAGGAGAGCAGTCTTGTGGA
AATTGATGGAGACTCTGAAAGCCTATCTCTAACAGCCTGTGACTATGGGGAAGAAGCTCTGAGT
CAACTTGTTTCTCCACTAAAACTGCAGCAGAGCCAGGAGACGGTGGAACACATCCAGAAAGGCT
TGAGCAATGGCTACTGTAAAGAGACTCTCCTCCCTTCTGAAATATTCAACAATATTCCAGGTGT
CAAAAATCAGAGTATTTCTCATCTAACCTATCAGGGTGCTGGCTTTGTGTATAACCATTTCTCA
AGTTCAGATGCAAAAACGAACCAAATCTGTGGGCCCCAGCAGCCTAGGGCTCCAGATATGCATG
TCCCTACACCCACACCCTCGACACATGCCCCTTTGGCTGCTTTGAAACTGCCAAGCCCATGCAA
ATCCAAAAGTCTGGGGGACTTAACATCAGAGGACATTGCCTGCAATTTTGAAAGCAAATACCAA
TGTATTAGTAGGAGTTTCGTGACAAACAGCATTAGAGACAAGAGCGTGACTATGAAGACAAAGT
CATTCGAGCCTCTAGATGCCCTAACTGAACAGCTCCGGAAGCTGGTGTCCTTTGACCAAGAAGA
CAGCTGTCAAGGGTTATACTCAAAGCAGGATGTCAATCAGTGTCCCAGGGCCTTAGTCAGAAAG
TTGTCCTCTAGAAGTCAGAGCAGAGTTCGCAACATTGCTAGTCGTGCCAAGGAGAAGCAGGAAG
CTGGCAAGCAAAAAGCTATGACTCAGAACCCCAGAGGAGGAGTGGTCCTTAGAAGTAAACCGCC
AGCTCCTACTCTGGCTGTGAACCGTCACTCCACGGGCTCATACATTGCAAGCTACCTGAGGAAC
ATGAAAGCTAGTGGCCTAGAAGGTCGCGGCATCCCAGAGGGAGCATGCACAGCCCTTCGCTACG
GCTACATGGACCAGTTCTGTTCAGACAATTCAGTTCTGCAGACTGAGCCAAGCAGTGAAGATAA
ACCCGAAATTTATTTTCTTTTGAGGCTTTGAACTATATAAAGCTACATCTTCATTGTTTACATG
ATATTCTCTAAGATGTTAGTTTTTTTTTCCATTGTCAGTAAATATGATACTGGGCTTGGAAATG
ATTTCCAAATGTACTTTTAAACTTGTATTTTGGTCTCCTGTTGCTCATGCATTTGTACATAGAT
TCTGTGACATGTCCCCGGAACCCACGACCTTTCCCCGGAGGTATTGTAAACTGTGTCAGTATAA
AATGTGTGCATGACCTCCATGTGAACCTTCTCAGCAGCTTGGGTCACAGTGTGCATATGTTGCA
CAGAAATGTTTTTCCCCGTGTCCTCCGATCACAGCCCCAGAGGCTGTCGCCGTTACTCACTAGG
TGTTGAGCTGATTGAGTTTAAACTTTGAGAACCATAAAGGGATGGTTTCTTTGTTGGGAGCTAC
ATTTTCCTTCTGAATTGAGAGACACAGATTCACTTTTATAATCCACTTAAGACCATTGTTTTAA
GTAGTTACCTTGCCCTTTCTGAGTTCCACATGCCACCAAAGTGGGAATTCCATAAAGATGGACA
GCCTCTCTCCAACCCCCAAAGTCCCTTTTAGAATAGGCCGTGAGGAAGAAAGTGAACTTCTGTA
TATAGGGACAAATTAGTTTGTTTTGCAATAAATTTTGTTACATATTTTTTGCTAA

hide sequence

RefSeq Acc Id:

XM_039102284 ⟹ XP_038958212

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,309,692 (-)	NCBI
mRatBN7.2	2	148,148,908 - 148,160,516 (-)	NCBI

RefSeq Acc Id:

XM_063281789 ⟹ XP_063137859

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,510,956 (-)	NCBI

RefSeq Acc Id:

XM_063281790 ⟹ XP_063137860

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,510,463 (-)	NCBI

RefSeq Acc Id:

XM_063281791 ⟹ XP_063137861

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,514,120 (-)	NCBI

RefSeq Acc Id:

XM_063281792 ⟹ XP_063137862

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,510,956 (-)	NCBI

RefSeq Acc Id:

XM_063281793 ⟹ XP_063137863

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,510,956 (-)	NCBI

RefSeq Acc Id:

XM_063281794 ⟹ XP_063137864

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,464,286 (-)	NCBI

RefSeq Acc Id:

XM_063281795 ⟹ XP_063137865

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,510,956 (-)	NCBI

RefSeq Acc Id:

XM_063281796 ⟹ XP_063137866

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,510,956 (-)	NCBI

RefSeq Acc Id:

XM_063281797 ⟹ XP_063137867

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,298,547 - 150,510,956 (-)	NCBI

RefSeq Acc Id:

XM_063281798 ⟹ XP_063137868

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,301,624 - 150,510,956 (-)	NCBI

RefSeq Acc Id:

XM_063281799 ⟹ XP_063137869

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,301,624 - 150,510,956 (-)	NCBI

RefSeq Acc Id:

XM_063281800 ⟹ XP_063137870

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	150,301,691 - 150,510,956 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178636	(Get FASTA)	NCBI Sequence Viewer
	XP_038958212	(Get FASTA)	NCBI Sequence Viewer
	XP_063137859	(Get FASTA)	NCBI Sequence Viewer
	XP_063137860	(Get FASTA)	NCBI Sequence Viewer
	XP_063137861	(Get FASTA)	NCBI Sequence Viewer
	XP_063137862	(Get FASTA)	NCBI Sequence Viewer
	XP_063137863	(Get FASTA)	NCBI Sequence Viewer
	XP_063137864	(Get FASTA)	NCBI Sequence Viewer
	XP_063137865	(Get FASTA)	NCBI Sequence Viewer
	XP_063137866	(Get FASTA)	NCBI Sequence Viewer
	XP_063137867	(Get FASTA)	NCBI Sequence Viewer
	XP_063137868	(Get FASTA)	NCBI Sequence Viewer
	XP_063137869	(Get FASTA)	NCBI Sequence Viewer
	XP_063137870	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM14812	(Get FASTA)	NCBI Sequence Viewer
	EDM14813	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000068040
	ENSRNOP00000068040.3
	ENSRNOP00000068291
	ENSRNOP00000068291.3

RefSeq Acc Id:

NP_001178636 ⟸ NM_001191707

- UniProtKB:

A0A096MJ91 (UniProtKB/TrEMBL), D4A4H0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKSEKAKILIDSIYKVTEGRQSEIFH
RQAEGNFDPSCCFTIYHGNHMESLDLITSNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQW
VKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKM
MSLRRDLYLLLLSYSDKKDHLTVEELAQFLKVEQKMSNVTLDYCLDVIKKFEVSEENKVKNVLG
IEGFTNFMRSPACDVFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQE
GCRCVEVDCWDGPDGEPVVHHGYTLTSKILFKDVVETINKHAFVKNEFPVILSIENHCSIQQQR
KIAQYLKGIFQDKLDLSSVDTGECRQLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSAD
EIEDECKFKLHYSNGTTEHQVESFIRKKLDSLLKESQIRDKEDPDSFTVRALLKATHEGLNAHL
KQNLDVKESGKKSHGRSLMANFGKHKKTPKSRSKSYSTDDEEDTLQNPGKEGGQLYRLGRRRRT
MKLCRELSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPS
AYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQINRAKFKANGNCGYILKPQQMCKGTFNPLS
GDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNG
FNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEGLTEASIF
VHITINEIFGKNRQLQGLKGLFNKNPRHGSSENNSHYVRKRSIGDRILRRTASAPAKGRKKSKV
GFQEMVEIKDSVCEATRDQDGVLRRTTRSLQLRPVSMPVDKNLLGALSLPISEAAKNTDGKENY
LAEDKDDGRKGPATIKDPHFSNFNKKLSSSSSALLHKDAKNQGPTASVSNPEQCGGLGLKSGRI
KPHMTNDCQENRSPQNFLSPRKHLALDPATKGLQDLHGMRTDEKEQERAKGFVGRKSTQSESVL
SQSSLEVENLEGSKAKGRAATSFSLSDVSALCSDIPDLHSTAILQDTEISDLINDVTLTNANES
GSSISALIGQFEESNHRANVAVVSRLLSTSGTSEGVALPVALGLQTPIKNGFSQGKHKASFLCS
SPELNKPSSAETTKLANNTVACGVIGSPISTPKPGDDASDKAKTRVTEDNLPDSPDAFPGQFPQ
SPTHGEDHRQVMSSPALSMPLAMEDTTADPALCINSEESSLVEIDGDSESLSLTACDYGEEALS
QLVSPLKLQQSQETVEHIQKGLSNGYCKETLLPSEIFNNIPGVKNQSISHLTYQGAGFVYNHFS
SSDAKTNQICGPQQPRAPDMHVPTPTPSTHAPLAALKLPSPCKSKSLGDLTSEDIACNFESKYQ
CISRSFVTNSIRDKSVTMKTKSFEPLDALTEQLRKLVSFDQEDSCQGLYSKQDVNQCPRALVRK
LSSRSQSRVRNIASRAKEKQEAGKQKAMTQNPRGGVVLRSKPPAPTLAVNRHSTGSYIASYLRN
MKASGLEGRGIPEGACTALRYGYMDQFCSDNSVLQTEPSSEDKPEIYFLLRL

hide sequence

Ensembl Acc Id:

ENSRNOP00000054535 ⟸ ENSRNOT00000057724

Ensembl Acc Id:

ENSRNOP00000068287 ⟸ ENSRNOT00000076274

Ensembl Acc Id:

ENSRNOP00000068040 ⟸ ENSRNOT00000076326

Ensembl Acc Id:

ENSRNOP00000068291 ⟸ ENSRNOT00000076165

RefSeq Acc Id:	XP_038958212 ⟸ XM_039102284
- Peptide Label:	isoform X11

RefSeq Acc Id:	XP_063137861 ⟸ XM_063281791
- Peptide Label:	isoform X1
- UniProtKB:	D4A4H0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137867 ⟸ XM_063281797
- Peptide Label:	isoform X7
- UniProtKB:	D4A4H0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137866 ⟸ XM_063281796
- Peptide Label:	isoform X6
- UniProtKB:	D4A4H0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137862 ⟸ XM_063281792
- Peptide Label:	isoform X2
- UniProtKB:	D4A4H0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137865 ⟸ XM_063281795
- Peptide Label:	isoform X5
- UniProtKB:	D4A4H0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137863 ⟸ XM_063281793
- Peptide Label:	isoform X3
- UniProtKB:	D4A4H0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137859 ⟸ XM_063281789
- Peptide Label:	isoform X1
- UniProtKB:	D4A4H0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137860 ⟸ XM_063281790
- Peptide Label:	isoform X1
- UniProtKB:	D4A4H0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137864 ⟸ XM_063281794
- Peptide Label:	isoform X4
- UniProtKB:	A0A096MJW8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137869 ⟸ XM_063281799
- Peptide Label:	isoform X9
- UniProtKB:	A0A096MJW5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137868 ⟸ XM_063281798
- Peptide Label:	isoform X8
- UniProtKB:	A0A096MJW5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137870 ⟸ XM_063281800
- Peptide Label:	isoform X10
- UniProtKB:	A0A096MJW5 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A096MJW8-F1-model_v2	AlphaFold	A0A096MJW8	1-1648	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561991	AgrOrtholog
BioCyc Gene	G2FUF-52926	BioCyc
BioCyc Pathway	PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis]	BioCyc
	PWY-6367 [D-myo-inositol-5-phosphate metabolism]	BioCyc
	PWY-8052 [2-arachidonoylglycerol biosynthesis]	BioCyc
BioCyc Pathway Image	PWY-6351	BioCyc
	PWY-6367	BioCyc
	PWY-8052	BioCyc
Ensembl Genes	ENSRNOG00000009955	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000076165	ENTREZGENE
	ENSRNOT00000076165.4	UniProtKB/TrEMBL
	ENSRNOT00000076326	ENTREZGENE
	ENSRNOT00000076326.3	UniProtKB/TrEMBL
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
	2.60.40.150	UniProtKB/TrEMBL
	3.20.20.190	UniProtKB/TrEMBL
	EF-hand	UniProtKB/TrEMBL
InterPro	C2_Ca-dep	UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/TrEMBL
	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	PH_domain	UniProtKB/TrEMBL
	PH_like_dom	UniProtKB/TrEMBL
	Phospholipase_C_Pinositol-sp_Y	UniProtKB/TrEMBL
	Pinositol_Phospholipase-C	UniProtKB/TrEMBL
	PLC-eta1	UniProtKB/TrEMBL
	PLC-like_Pdiesterase_TIM-brl	UniProtKB/TrEMBL
	PLCeta1_EF	UniProtKB/TrEMBL
	PLipase_C_EF-hand-like	UniProtKB/TrEMBL
	PLipase_C_PInositol-sp_X_dom	UniProtKB/TrEMBL
KEGG Report	rno:310463	UniProtKB/TrEMBL
NCBI Gene	310463	ENTREZGENE
PANTHER	PTHR10336	UniProtKB/TrEMBL
	PTHR10336:SF51	UniProtKB/TrEMBL
Pfam	EF-hand_like	UniProtKB/TrEMBL
	PF00168	UniProtKB/TrEMBL
	PH_12	UniProtKB/TrEMBL
	PI-PLC-X	UniProtKB/TrEMBL
	PI-PLC-Y	UniProtKB/TrEMBL
PhenoGen	Plch1	PhenoGen
PRINTS	PHPHLIPASEC	UniProtKB/TrEMBL
PROSITE	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
	PH_DOMAIN	UniProtKB/TrEMBL
	PIPLC_X_DOMAIN	UniProtKB/TrEMBL
	PIPLC_Y_DOMAIN	UniProtKB/TrEMBL
	PS50004	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000009955	RatGTEx
SMART	EFh	UniProtKB/TrEMBL
	PLCXc	UniProtKB/TrEMBL
	PLCYc	UniProtKB/TrEMBL
	SM00233	UniProtKB/TrEMBL
	SM00239	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
	PLC-like_Pdiesterase_TIM-brl	UniProtKB/TrEMBL
	SSF47473	UniProtKB/TrEMBL
	SSF49562	UniProtKB/TrEMBL
UniProt	A0A096MJ91	ENTREZGENE, UniProtKB/TrEMBL
	A0A096MJW5	ENTREZGENE
	A0A096MJW8	ENTREZGENE, UniProtKB/TrEMBL
	D4A4H0	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Plch1	phospholipase C, eta 1	Plcl3_predicted	phospholipase C-like 3 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Plcl3_predicted	phospholipase C-like 3 (predicted)	RGD1561991_predicted	similar to Hypothetical protein MGC57096 (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-07	RGD1561991_predicted	similar to Hypothetical protein MGC57096 (predicted)	LOC310463	similar to Hypothetical protein MGC57096	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC310463	similar to Hypothetical protein MGC57096			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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