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Gene: Tmem270 (transmembrane protein 270) Rattus norvegicus

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Symbol:

Tmem270

Name:

transmembrane protein 270

RGD ID:

1561903

Description:

Predicted to be located in membrane. Orthologous to human TMEM270 (transmembrane protein 270); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; cefaloridine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC288604; RGD1561903; similar to Williams-Beuren syndrome critical region protein 28 isoform A; Wbscr28; Williams-Beuren syndrome chromosome region 28; Williams-Beuren syndrome chromosome region 28 (human)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM270 (transmembrane protein 270)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Tmem270 (transmembrane protein 270)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem270 (transmembrane protein 270)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM270 (transmembrane protein 270)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM270 (transmembrane protein 270)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem270 (transmembrane protein 270)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM270 (transmembrane protein 270)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM270 (transmembrane protein 270)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem270 (transmembrane protein 270)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	COX6A1 (cytochrome c oxidase subunit 6A1)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Tmem270 (transmembrane protein 270)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	TMEM270 (transmembrane protein 270)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	27,430,092 - 27,435,243 (+)	NCBI		GRCr8
mRatBN7.2	12	21,793,631 - 21,798,723 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	21,794,130 - 21,798,731 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	12	24,803,204 - 24,808,287 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	24,803,686 - 24,808,288 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	26,803,487 - 26,808,557 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	22,858,647 - 22,863,206 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	23,554,551 - 23,559,628 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem270	Rat	autism spectrum disorder		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autism spectrum disorder	ClinVar	PMID:21658581 more ...
Tmem270	Rat	autistic disorder		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Autism	ClinVar	PMID:21681106 and PMID:30208311
Tmem270	Rat	intestinal volvulus		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: INTESTINAL MALROTATION and FAMILIAL	ClinVar	PMID:25741868
Tmem270	Rat	Neurodevelopmental Disorders		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868
Tmem270	Rat	pleomorphic xanthoastrocytoma		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Pleomorphic xanthoastrocytoma	ClinVar	PMID:28299358
Tmem270	Rat	schizophrenia		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Schizophrenia	ClinVar	PMID:21681106 and PMID:30208311
Tmem270	Rat	supravalvular aortic stenosis		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Supravalvar aortic stenosis	ClinVar	PMID:10627943 more ...
Tmem270	Rat	Volvulus Of Midgut		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Volvulus of midgut	ClinVar	PMID:25741868
Tmem270	Rat	Williams-Beuren syndrome		ISO	TMEM270 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Williams syndrome	ClinVar	PMID:25741868

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem270	Rat	17beta-hydroxy-5alpha-androstan-3-one	decreases expression	ISO	TMEM270 (Homo sapiens)	6480464	Dihydrotestosterone results in decreased expression of TMEM270 mRNA	CTD	PMID:17624924
Tmem270	Rat	3,4-methylenedioxymethamphetamine	increases expression	ISO	Tmem270 (Mus musculus)	6480464	N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of TMEM270 mRNA	CTD	PMID:20188158
Tmem270	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of TMEM270 mRNA	CTD	PMID:24780913
Tmem270	Rat	aflatoxin B1	decreases methylation	ISO	TMEM270 (Homo sapiens)	6480464	Aflatoxin B1 results in decreased methylation of TMEM270 intron	CTD	PMID:30157460
Tmem270	Rat	arsane	affects methylation	ISO	TMEM270 (Homo sapiens)	6480464	Arsenic affects the methylation of TMEM270 gene	CTD	PMID:25304211
Tmem270	Rat	arsenic atom	affects methylation	ISO	TMEM270 (Homo sapiens)	6480464	Arsenic affects the methylation of TMEM270 gene	CTD	PMID:25304211
Tmem270	Rat	benzo[a]pyrene	increases methylation	ISO	TMEM270 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of TMEM270 promoter	CTD	PMID:27901495
Tmem270	Rat	benzo[e]pyrene	decreases methylation	ISO	TMEM270 (Homo sapiens)	6480464	benzo(e)pyrene results in decreased methylation of TMEM270 intron	CTD	PMID:30157460
Tmem270	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of TMEM270 mRNA	CTD	PMID:25181051 and PMID:30816183
Tmem270	Rat	butanal	increases expression	ISO	TMEM270 (Homo sapiens)	6480464	butyraldehyde results in increased expression of TMEM270 mRNA	CTD	PMID:26079696
Tmem270	Rat	cadmium dichloride	increases expression	ISO	TMEM270 (Homo sapiens)	6480464	Cadmium Chloride results in increased expression of TMEM270 mRNA	CTD	PMID:26472689
Tmem270	Rat	cefaloridine	increases expression	EXP		6480464	Cephaloridine results in increased expression of TMEM270 mRNA	CTD	PMID:18500788
Tmem270	Rat	CGP 52608	multiple interactions	ISO	TMEM270 (Homo sapiens)	6480464	CGP 52608 promotes the reaction [RORA protein binds to TMEM270 gene]	CTD	PMID:28238834
Tmem270	Rat	methapyrilene	decreases methylation	ISO	TMEM270 (Homo sapiens)	6480464	Methapyrilene results in decreased methylation of TMEM270 intron	CTD	PMID:30157460
Tmem270	Rat	methoxychlor	affects methylation	EXP		6480464	Methoxychlor affects the methylation of TMEM270 gene	CTD	PMID:35440735
Tmem270	Rat	paracetamol	affects expression	ISO	Tmem270 (Mus musculus)	6480464	Acetaminophen affects the expression of TMEM270 mRNA	CTD	PMID:17562736
Tmem270	Rat	paracetamol	decreases expression	EXP		6480464	Acetaminophen results in decreased expression of TMEM270 mRNA	CTD	PMID:33387578
Tmem270	Rat	pentanal	increases expression	ISO	TMEM270 (Homo sapiens)	6480464	pentanal results in increased expression of TMEM270 mRNA	CTD	PMID:26079696
Tmem270	Rat	permethrin	decreases expression	ISO	TMEM270 (Homo sapiens)	6480464	Permethrin results in decreased expression of TMEM270 mRNA	CTD	PMID:37047231
Tmem270	Rat	propanal	increases expression	ISO	TMEM270 (Homo sapiens)	6480464	propionaldehyde results in increased expression of TMEM270 mRNA	CTD	PMID:26079696
Tmem270	Rat	silicon dioxide	decreases expression	ISO	TMEM270 (Homo sapiens)	6480464	Silicon Dioxide analog results in decreased expression of TMEM270 mRNA	CTD	PMID:25895662
Tmem270	Rat	silver atom	increases expression	ISO	Tmem270 (Mus musculus)	6480464	Silver results in increased expression of TMEM270 mRNA	CTD	PMID:27131904
Tmem270	Rat	silver(0)	increases expression	ISO	Tmem270 (Mus musculus)	6480464	Silver results in increased expression of TMEM270 mRNA	CTD	PMID:27131904
Tmem270	Rat	sotorasib	multiple interactions	ISO	TMEM270 (Homo sapiens)	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TMEM270 mRNA	CTD	PMID:36139627
Tmem270	Rat	trametinib	multiple interactions	ISO	TMEM270 (Homo sapiens)	6480464	[sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in increased expression of TMEM270 mRNA	CTD	PMID:36139627
Tmem270	Rat	vinclozolin	increases methylation	EXP		6480464	vinclozolin results in increased methylation of TMEM270 gene	CTD	PMID:31682807

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Tmem270	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Tmem270
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	27,430,092 - 27,435,243 (+)	NCBI		GRCr8
mRatBN7.2	12	21,793,631 - 21,798,723 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	21,794,130 - 21,798,731 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	12	24,803,204 - 24,808,287 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	24,803,686 - 24,808,288 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	26,803,487 - 26,808,557 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	22,858,647 - 22,863,206 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	23,554,551 - 23,559,628 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

TMEM270
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	73,860,848 - 73,865,890 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	73,861,159 - 73,865,890 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	73,275,489 - 73,280,220 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	72,913,425 - 72,918,159 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	68,754,191 - 68,758,926 (+)	NCBI		Celera
Cytogenetic Map	7	q11.23	NCBI
HuRef	7	69,158,848 - 69,163,564 (+)	NCBI		HuRef
CHM1_1	7	73,420,949 - 73,425,683 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	75,061,792 - 75,066,837 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	72,608,561 - 72,613,295 (+)	NCBI

Tmem270
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	134,930,447 - 134,935,587 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	134,930,447 - 134,935,587 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	134,901,593 - 134,906,733 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	134,901,593 - 134,906,733 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	135,377,464 - 135,382,603 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	135,186,221 - 135,191,360 (-)	NCBI		MGSCv36	mm8
Celera	5	131,912,152 - 131,917,291 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	74.88	NCBI

Tmem270
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955456	13,947,773 - 13,953,965 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM270
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	91,037,439 - 91,048,490 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	139,302,070 - 139,313,122 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1	7	81,011,217 - 81,016,100 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	81,011,217 - 81,016,100 (+)	Ensembl	panpan1.1		panPan2

TMEM270
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	6,472,495 - 6,475,051 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	6,472,520 - 6,474,976 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	8,170,118 - 8,172,674 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	6,287,508 - 6,290,064 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	6,286,533 - 6,289,989 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	6,277,242 - 6,279,798 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	6,225,118 - 6,227,687 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	6,388,863 - 6,391,438 (-)	NCBI		UU_Cfam_GSD_1.0

Tmem270
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	131,029,940 - 131,032,296 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936543	3,004,326 - 3,006,608 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936543	3,004,326 - 3,006,608 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM270
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	11,075,901 - 11,078,442 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	11,059,177 - 11,079,858 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	10,752,341 - 10,768,852 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM270
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	9,212,358 - 9,217,628 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	9,212,377 - 9,217,517 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666070	7,273,087 - 7,296,893 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem270
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624740	14,017,188 - 14,021,587 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Tmem270
37 total Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain	Variant Page
12	26807377	26807378	C	T	snv	IS/Kyo (KyushuU), DOB/Oda (KyushuU), IS-Tlk/Kyo (KyushuU)	View more Information

Predicted Target Of

	Summary Value
Count of predictions:	37
Count of miRNA genes:	36
Interacting mature miRNAs:	37
Transcripts:	ENSRNOT00000033499
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	19144362	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	19610870	46669029	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	8525423	28064601	Rat
737822	Alc10	Alcohol consumption QTL 10	2.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	12	19610870	40218516	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	15872653	32974238	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	23297788	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	34851688	Rat
10755457	Coatc14	Coat color QTL 14		0.01759	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	12	1	22591684	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	9318216	32103380	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610889	35682913	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	28064557	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	19835789	38193007	Rat
2306789	Ean6	Experimental allergic neuritis QTL 6	4.9		nervous system integrity trait (VT:0010566)	experimental autoimmune neuritis severity score (CMO:0001528)	12	19610870	24139202	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	20328819	46669029	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610870	42828880	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	29333307	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	11073825	24234895	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	13635523	30827399	Rat
631521	Pia12	Pristane induced arthritis QTL 12	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	20259417	23672083	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	36247923	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	13635523	35682913	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	8449490	28302290	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	15550826	38478808	Rat

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
8	6	36	106	35	40	13	15	13	6	122	67	93	31	56	27


RefSeq Transcripts	NM_001431982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001431985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_001077705	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598506	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604475	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604476	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_213758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000033499 ⟹ ENSRNOP00000034323

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	21,794,130 - 21,798,731 (+)	Ensembl
Rnor_6.0 Ensembl	12	24,803,686 - 24,808,288 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114794 ⟹ ENSRNOP00000082087

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	21,794,130 - 21,798,731 (+)	Ensembl

RefSeq Acc Id:

XM_006249213 ⟹ XP_006249275

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	27,430,092 - 27,435,243 (+)	NCBI
mRatBN7.2	12	21,793,631 - 21,798,723 (+)	NCBI
Rnor_6.0	12	24,803,204 - 24,808,287 (+)	NCBI
Rnor_5.0	12	26,803,487 - 26,808,557 (+)	NCBI

Sequence:

show sequence

TCAGCTGGTCCTTCCTGGTTCTCTGAATGGAGAAACTCCAAGACTGCACACTCATTCTCCAGCCTGAAACTGATGGGGACAGGGAAGGGACAGGGAAGGGACAGGGAGAGAGGCCTGGTGGTGAGGAT
AATGGGGTGTCAGTTGAGGAAGCTAAGCTGGGGCTTCTCCTATGGCAAATCTGCTACCCTCAGGGTCCGATCTGGAAGCTGATCCAGAACCGTATTCACTTGTACCAATTTCTCCTTCTGAAGATGGC
CATCTTTCAGCACTGGGTGTCGGGACTAGCCCAGGAAGCCCGGGGTTCTGGCAGTGACCAGGCCTGCCTACTTCCAGAAGTCATCATAACCTATGCTCTGGGCTTGGTCCTTCGAGCTGGACTGGCAT
TGCTGTGGGTCCCTATGTGGCTGCTGCTCTGGGGACCCAGGTTGTCATACAGAGTCGGACTGTGCTGCACCCACACTATGAAGCTGGCCCTGGGGCACCTCTGTGCCTGGGAACCTCCGGGTCTGTCT
CCAGCCACCTTCAGGGACCTGTTTCTATCCTGCCTGCATCGCCTGATGCTGGTGGCCTTGCTGGTACTGCTGCTAACCTGGAAGCTGTTGCAGAAAGCCCATCACTCCAGTCTGGGCTGGCTGCACAG
CCAGAGTTCTATGCTCCTGGAAGCCCTGGCTTTGCTGAGACGCCTCTACCTGTGGGTGGAGCACAGGACCACACTCACTTCCTGGAACCTGGCCTATCTTGTCACTTGGACTACCTGTCTCGCTTCCC
ACCTGCTTCAAGCTGCCTTTGAGCACACAGCCCAACTGGCCCAGGCCCAGGAGGTCTCATTCGAGGAGACCTCAGAGCCCTCATCTCAGTTCTTAATTCCAGAATCCTCCACCACCGAGTCTGGACCC
CTCCCTTCCCAGCCTGAAACCCCCGGAGAATAAATGTGTCCCCCACCTGCC

hide sequence

RefSeq Acc Id:

XM_017598507 ⟹ XP_017453996

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	27,430,657 - 27,435,243 (+)	NCBI
mRatBN7.2	12	21,794,137 - 21,798,723 (+)	NCBI
Rnor_6.0	12	24,803,700 - 24,808,287 (+)	NCBI

Sequence:

show sequence

TGGCTGGAGGAATGGACGGAGGCCAGACATGGAGGCCGCTCCCCGGGTCAGATTTGGCCTTCCT
AGAATTCTCCTGCAGGTTGGGAAGCTCTCTGCGCTGCTTTCCTCATGATGACAAGGGCAACCAGGGTCCCAGGCGAGCCCAGGGATTTGGGGGAAGCCAGCCAGCCGTGTGTTCGAATCCCACAGTTA
ATCAGAGGGGAGCTGATCCAGAACCGTATTCACTTGTACCAATTTCTCCTTCTGAAGATGGCCATCTTTCAGCACTGGGTGTCGGGACTAGCCCAGGAAGCCCGGGGTTCTGGCAGTGACCAGGCCTG
CCTACTTCCAGAAGTCATCATAACCTATGCTCTGGGCTTGGTCCTTCGAGCTGGACTGGCATTGCTGTGGGTCCCTATGTGGCTGCTGCTCTGGGGACCCAGGTTGTCATACAGAGTCGGACTGTGCT
GCACCCACACTATGAAGCTGGCCCTGGGGCACCTCTGTGCCTGGGAACCTCCGGGTCTGTCTCCAGCCACCTTCAGGGACCTGTTTCTATCCTGCCTGCATCGCCTGATGCTGGTGGCCTTGCTGGTA
CTGCTGCTAACCTGGAAGCTGTTGCAGAAAGCCCATCACTCCAGTCTGGGCTGGCTGCACAGCCAGAGTTCTATGCTCCTGGAAGCCCTGGCTTTGCTGAGACGCCTCTACCTGTGGGTGGAGCACAG
GACCACACTCACTTCCTGGAACCTGGCCTATCTTGTCACTTGGACTACCTGTCTCGCTTCCCACCTGCTTCAAGCTGCCTTTGAGCACACAGCCCAACTGGCCCAGGCCCAGGAGGTCTCATTCGAGG
AGACCTCAGAGCCCTCATCTCAGTTCTTAATTCCAGAATCCTCCACCACCGAGTCTGGACCCCTCCCTTCCCAGCCTGAAACCCCCGGAGAATAAATGTGTCCCCCACCTGCC

hide sequence

RefSeq Acc Id:

XM_213758 ⟹ XP_213758

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	27,430,533 - 27,435,243 (+)	NCBI
mRatBN7.2	12	21,794,110 - 21,798,723 (+)	NCBI
Rnor_6.0	12	24,803,689 - 24,808,287 (+)	NCBI
Rnor_5.0	12	26,803,487 - 26,808,557 (+)	NCBI
RGSC_v3.4	12	22,858,647 - 22,863,206 (+)	RGD

Sequence:

show sequence

CCTGCCTCTCCTGGCTGGAGGAATGGACGGAGGCCAGACATGGAGGCCGCTCCCCGGGTCAGATTTGGCCTTCCTAGAATTCTCCTGCAGGTTGGGAAGCTCTCTGCGCTGCTGATCCAGAACCGTAT
TCACTTGTACCAATTTCTCCTTCTGAAGATGGCCATCTTTCAGCACTGGGTGTCGGGACTAGCCCAGGAAGCCCGGGGTTCTGGCAGTGACCAGGCCTGCCTACTTCCAGAAGTCATCATAACCTATG
CTCTGGGCTTGGTCCTTCGAGCTGGACTGGCATTGCTGTGGGTCCCTATGTGGCTGCTGCTCTGGGGACCCAGGTTGTCATACAGAGTCGGACTGTGCTGCACCCACACTATGAAGCTGGCCCTGGGG
CACCTCTGTGCCTGGGAACCTCCGGGTCTGTCTCCAGCCACCTTCAGGGACCTGTTTCTATCCTGCCTGCATCGCCTGATGCTGGTGGCCTTGCTGGTACTGCTGCTAACCTGGAAGCTGTTGCAGAA
AGCCCATCACTCCAGTCTGGGCTGGCTGCACAGCCAGAGTTCTATGCTCCTGGAAGCCCTGGCTTTGCTGAGACGCCTCTACCTGTGGGTGGAGCACAGGACCACACTCACTTCCTGGAACCTGGCCT
ATCTTGTCACTTGGACTACCTGTCTCGCTTCCCACCTGCTTCAAGCTGCCTTTGAGCACACAGCCCAACTGGCCCAGGCCCAGGAGGTCTCATTCGAGGAGACCTCAGAGCCCTCATCTCAGTTCTTA
ATTCCAGAATCCTCCACCACCGAGTCTGGACCCCTCCCTTCCCAGCCTGAAACCCCCGGAGAATAAATGTGTCCCCCACCTGCC

hide sequence


Protein RefSeqs	NP_001418911	(Get FASTA)	NCBI Sequence Viewer
	NP_001418912	(Get FASTA)	NCBI Sequence Viewer
	NP_001418913	(Get FASTA)	NCBI Sequence Viewer
	NP_001418914	(Get FASTA)	NCBI Sequence Viewer
	XP_006249275	(Get FASTA)	NCBI Sequence Viewer
	XP_017453996	(Get FASTA)	NCBI Sequence Viewer
	XP_213758	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034323
	ENSRNOP00000034323.3
	ENSRNOP00000082087
	ENSRNOP00000082087.1
	ENSRNOP00000106875

RefSeq Acc Id:

XP_213758 ⟸ XM_213758

- Peptide Label:

isoform X3

- Sequence:

show sequence

MEAAPRVRFGLPRILLQVGKLSALLIQNRIHLYQFLLLKMAIFQHWVSGLAQEARGSGSDQACLLPEVIITYALGLVLRAGLALLWVPMWLLLWGPRLSYRVGLCCTHTMKLALGHLCAWEPPGLSPA
TFRDLFLSCLHRLMLVALLVLLLTWKLLQKAHHSSLGWLHSQSSMLLEALALLRRLYLWVEHRTTLTSWNLAYLVTWTTCLASHLLQAAFEHTAQLAQAQEVSFEETSEPSSQFLIPESSTTESGPLP
SQPETPGE

hide sequence

RefSeq Acc Id:

XP_006249275 ⟸ XM_006249213

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEKLQDCTLILQPETDGDREGTGKGQGERPGGEDNGVSVEEAKLGLLLWQICYPQGPIWKLIQN
RIHLYQFLLLKMAIFQHWVSGLAQEARGSGSDQACLLPEVIITYALGLVLRAGLALLWVPMWLLLWGPRLSYRVGLCCTHTMKLALGHLCAWEPPGLSPATFRDLFLSCLHRLMLVALLVLLLTWKLL
QKAHHSSLGWLHSQSSMLLEALALLRRLYLWVEHRTTLTSWNLAYLVTWTTCLASHLLQAAFEHTAQLAQAQEVSFEETSEPSSQFLIPESSTTESGPLPSQPETPGE

hide sequence

RefSeq Acc Id:

XP_017453996 ⟸ XM_017598507

- Peptide Label:

isoform X2

- Sequence:

show sequence

MMTRATRVPGEPRDLGEASQPCVRIPQLIRGELIQNRIHLYQFLLLKMAIFQHWVSGLAQEARGSGSDQACLLPEVIITYALGLVLRAGLALLWVPMWLLLWGPRLSYRVGLCCTHTMKLALGHLCAW
EPPGLSPATFRDLFLSCLHRLMLVALLVLLLTWKLLQKAHHSSLGWLHSQSSMLLEALALLRRLYLWVEHRTTLTSWNLAYLVTWTTCLASHLLQAAFEHTAQLAQAQEVSFEETSEPSSQFLIPESS
TTESGPLPSQPETPGE

hide sequence

Ensembl Acc Id:

ENSRNOP00000034323 ⟸ ENSRNOT00000033499

Ensembl Acc Id:

ENSRNOP00000082087 ⟸ ENSRNOT00000114794

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZKV0-F1-model_v2	AlphaFold	D3ZKV0	1-264	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13698570

Promoter ID:

EPDNEW_R9090

Type:

single initiation site

Name:

Tmem270_1

Description:

transmembrane protein 270

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	24,803,694 - 24,803,754	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-19588	BioCyc
Ensembl Genes	ENSRNOG00000001474	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000033499	ENTREZGENE
	ENSRNOT00000033499.6	UniProtKB/TrEMBL
	ENSRNOT00000114794	ENTREZGENE
	ENSRNOT00000114794.1	UniProtKB/TrEMBL
	ENSRNOT00000165625	ENTREZGENE
InterPro	WBS28	UniProtKB/TrEMBL
NCBI Gene	288604	ENTREZGENE
PANTHER	PTHR37369	UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 270	UniProtKB/TrEMBL
Pfam	WBS28	UniProtKB/TrEMBL
PhenoGen	Tmem270	PhenoGen
RatGTEx	ENSRNOG00000001474	RatGTEx
UniProt	A0A8I6G8Y8	ENTREZGENE, UniProtKB/TrEMBL
	D3ZKV0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-05-18	Tmem270	transmembrane protein 270	Wbscr28	Williams-Beuren syndrome chromosome region 28	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-02-04	Wbscr28	Williams-Beuren syndrome chromosome region 28	Wbscr28	Williams-Beuren syndrome chromosome region 28 (human)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-29	Wbscr28	Williams-Beuren syndrome chromosome region 28 (human)	RGD1561903_predicted	similar to Williams-Beuren syndrome critical region protein 28 isoform A (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1561903_predicted	similar to Williams-Beuren syndrome critical region protein 28 isoform A (predicted)	LOC288604	similar to Williams-Beuren syndrome critical region protein 28 isoform A	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC288604	similar to Williams-Beuren syndrome critical region protein 28 isoform A			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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Imported Disease Annotations - ClinVar