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Gene: Il1rapl2 (interleukin 1 receptor accessory protein-like 2) Rattus norvegicus

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Symbol:

Il1rapl2

Name:

interleukin 1 receptor accessory protein-like 2

RGD ID:

1561761

Description:

Predicted to enable hydrolase activity and interleukin-1, type II, blocking receptor activity. Predicted to be involved in cell surface receptor signaling pathway and regulation of presynapse assembly. Predicted to be located in membrane and synapse. Predicted to be active in cell surface; glutamatergic synapse; and plasma membrane. Orthologous to human IL1RAPL2 (interleukin 1 receptor accessory protein like 2); INTERACTS WITH atrazine; bisphenol A; vinclozolin.

Type:

protein-coding

RefSeq Status:

INFERRED

Previously known as:

LOC300913; RGD1561761; similar to TIGIRR-1; X-linked interleukin-1 receptor accessory protein-like 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	105,547,403 - 107,080,369 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	105,754,490 - 107,065,223 (+)	Ensembl				GRCr8
mRatBN7.2	X	100,961,509 - 102,271,753 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	100,961,812 - 102,271,753 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	103,091,652 - 104,402,604 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	106,590,329 - 107,901,342 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	104,159,516 - 105,470,309 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	108,287,034 - 109,851,075 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	108,287,068 - 109,851,047 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	109,679,033 - 109,708,181 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	X	108,785,045 - 109,131,750 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	X	108,150,787 - 108,254,866 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	125,013,154 - 126,352,850 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	101,764,259 - 103,062,805 (+)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3',4,4',5-Pentachlorobiphenyl (ISO)

aflatoxin B1 (ISO)

amphotericin B (ISO)

aripiprazole (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

CGP 52608 (ISO)

choline (ISO)

dibutyl phthalate (ISO)

elemental selenium (ISO)

epoxiconazole (ISO)

folic acid (ISO)

FR900359 (ISO)

hydralazine (ISO)

L-methionine (ISO)

lead(0) (ISO)

ozone (ISO)

phorbol 13-acetate 12-myristate (ISO)

potassium dichromate (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell surface receptor signaling pathway (IBA)

cytokine-mediated signaling pathway (IEA)

nervous system development (IEA)

regulation of presynapse assembly (ISO)

signal transduction (IEA)

Cellular Component

cell surface (IBA,IEA)

glutamatergic synapse (ISO)

membrane (IEA)

plasma membrane (IBA)

synapse (IEA)

Molecular Function

hydrolase activity (IEA)

interleukin-1, type II, blocking receptor activity (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15632090	PMID:21926414

Genomics

Comparative Map Data

Il1rapl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	105,547,403 - 107,080,369 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	105,754,490 - 107,065,223 (+)	Ensembl				GRCr8
mRatBN7.2	X	100,961,509 - 102,271,753 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	100,961,812 - 102,271,753 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	103,091,652 - 104,402,604 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	106,590,329 - 107,901,342 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	104,159,516 - 105,470,309 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	108,287,034 - 109,851,075 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	108,287,068 - 109,851,047 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	109,679,033 - 109,708,181 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	X	108,785,045 - 109,131,750 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Rnor_5.0	X	108,150,787 - 108,254,866 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	125,013,154 - 126,352,850 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	101,764,259 - 103,062,805 (+)	NCBI		Celera
Cytogenetic Map	X	q32	NCBI

IL1RAPL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	104,566,199 - 105,767,829 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	104,566,199 - 105,767,829 (+)	Ensembl			hg38	GRCh38
GRCh37	X	103,810,880 - 105,011,822 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	103,697,652 - 104,898,478 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	103,617,140 - 104,817,967	NCBI
Celera	X	104,285,598 - 105,486,376 (+)	NCBI		Celera
Cytogenetic Map	X	q22.3	NCBI
HuRef	X	93,435,071 - 94,637,503 (+)	NCBI		HuRef
CHM1_1	X	103,721,823 - 104,923,126 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	102,997,341 - 104,199,639 (+)	NCBI		T2T-CHM13v2.0

Il1rapl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	136,471,503 - 137,749,826 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	136,471,357 - 137,747,695 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	137,570,754 - 138,849,077 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	137,570,608 - 138,846,946 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	134,106,088 - 135,381,494 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	132,917,913 - 134,193,319 (+)	NCBI		MGSCv36	mm8
Celera	X	120,847,137 - 122,116,600 (+)	NCBI		Celera
Cytogenetic Map	X	F1	NCBI
cM Map	X	59.1	NCBI

Il1rapl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955548	1,518,695 - 2,623,232 (+)	Ensembl
ChiLan1.0	NW_004955548	1,462,746 - 2,623,622 (+)	NCBI	ChiLan1.0	ChiLan1.0

IL1RAPL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	104,717,496 - 105,287,774 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	104,721,096 - 105,291,374 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	93,689,575 - 94,904,887 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	104,068,596 - 105,283,662 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	104,161,023 - 105,283,494 (+)	Ensembl			panPan2	panpan1.1

IL1RAPL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	77,918,264 - 78,959,932 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	64,099,554 - 65,432,679 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	79,587,004 - 80,920,111 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	X	77,071,569 - 78,402,563 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	78,775,315 - 80,098,087 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	79,222,860 - 79,875,803 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Il1rapl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	77,812,504 - 78,870,601 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	8,790,139 - 9,771,800 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	8,788,093 - 9,048,583 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IL1RAPL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	85,347,857 - 86,463,507 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	85,347,867 - 86,464,670 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	100,533,436 - 100,826,715 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IL1RAPL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	92,433,337 - 93,646,131 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666065	17,367,671 - 18,110,505 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Il1rapl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624803	10,919,651 - 12,243,480 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624803	10,917,671 - 12,315,002 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Il1rapl2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	90,669,433 - 90,787,672 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Il1rapl2
5566 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	66
Count of miRNA genes:	57
Interacting mature miRNAs:	59
Transcripts:	ENSRNOT00000040816
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	97528096	142528096	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	105359969	157758123	Rat
61430	Cia18	Collagen induced arthritis QTL 18	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	80434318	125434318	Rat
738029	Stresp2	Stress response QTL 2	3.4	0.0004	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	92979612	117740458	Rat
61431	Cia19	Collagen induced arthritis QTL 19	4.4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	X	105468858	125434318	Rat
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	45182909	117740458	Rat
2302047	Pia34	Pristane induced arthritis QTL 34	5.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	19	96916163	141916163	Rat

Markers in Region

DXGot100

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	X	106,268,908 - 106,269,096 (+)	Marker Load Pipeline
mRatBN7.2	X	101,475,391 - 101,475,579 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	108,816,216 - 108,816,403	NCBI	Rnor6.0
Rnor_5.0	X	108,677,912 - 108,678,099	UniSTS	Rnor5.0
RGSC_v3.4	X	125,548,486 - 125,548,673	UniSTS	RGSC3.4
Celera	X	102,279,261 - 102,279,448	UniSTS
Cytogenetic Map	X	q35	UniSTS

DXGot130

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	101,018,161 - 101,018,313 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	108,343,883 - 108,344,032	NCBI	Rnor6.0
Rnor_5.0	X	108,207,636 - 108,207,785	UniSTS	Rnor5.0
RGSC_v3.4	X	125,069,811 - 125,069,960	UniSTS	RGSC3.4
Celera	X	101,820,860 - 101,821,009	UniSTS
Cytogenetic Map	X	q35	UniSTS

AU047308

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	101,526,089 - 101,526,269 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	108,866,761 - 108,866,940	NCBI	Rnor6.0
Rnor_5.0	X	108,728,457 - 108,728,636	UniSTS	Rnor5.0
RGSC_v3.4	X	125,599,182 - 125,599,361	UniSTS	RGSC3.4
Celera	X	102,330,455 - 102,330,634	UniSTS
Cytogenetic Map	X	q35	UniSTS

RH138132

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	101,278,752 - 101,278,939 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	108,605,192 - 108,605,378	NCBI	Rnor6.0
Rnor_5.0	X	108,468,362 - 108,468,548	UniSTS	Rnor5.0
RGSC_v3.4	X	125,342,880 - 125,343,066	UniSTS	RGSC3.4
Celera	X	102,081,958 - 102,082,144	UniSTS
Cytogenetic Map	X	q35	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
2	4	99	19	11	7	1	7	1	64	12	98	43	48	4	15	15

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001166342	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279884	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063279886	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000093348 ⟹ ENSRNOP00000076241

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	105,754,490 - 107,065,223 (+)	Ensembl
mRatBN7.2 Ensembl	X	100,961,812 - 102,271,753 (+)	Ensembl
Rnor_6.0 Ensembl	X	108,287,068 - 109,851,047 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000122842 ⟹ ENSRNOP00000102006

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	106,277,068 - 107,065,223 (+)	Ensembl

RefSeq Acc Id:

NM_001166342 ⟹ NP_001159814

RefSeq Status:

INFERRED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	105,753,765 - 107,065,223 (+)	NCBI
mRatBN7.2	X	100,961,509 - 102,271,753 (+)	NCBI
Rnor_6.0	X	108,287,034 - 109,851,075 (+)	NCBI
Rnor_5.0	X	109,679,033 - 109,708,181 (+)	NCBI
Rnor_5.0	X	108,150,787 - 108,254,866 (+)	NCBI
Rnor_5.0	X	108,785,045 - 109,131,750 (+)	NCBI
RGSC_v3.4	X	125,013,154 - 126,352,850 (+)	RGD
Celera	X	101,764,259 - 103,062,805 (+)	RGD

Sequence:

show sequence

TTTCTAATTCGCACCTCGCGGTTGCAGTCAGTCAGCCAGGAGGCACCAAACTGTTAGCAACGAA
GCCCAGGCTCTGGGTGACTTCCACTACCCTCCCACTTCCCTACTCCAGGCATATTTCGGAGGCG
CTCCAGCGACAGTGGCAGGATGTGAGAGGAGCGCAGCGCTTACTCCTCGCATTCCTCTCTTTGA
GGGCTGGGGGGCCAGTGGCTTCTGCTCACCGGCTGGGGGGGGGGGGGCTCTGGGAAGCGCAGGA
GACGCGCAGGACGGAGGCGGGCGAGCCAGGTTCATGCCAGGCTGCCTGCACCGCAGCCCGTCTG
AGCCTGAGGCTCCGCTGTTTTCTCGTGTCCCGTGAGCGGAGGTAGCACCGCCGACTAGGGTGCC
CCGCGTCCCGCGTCCCAGCTCCCAGCCTGGTGCGCACCGTTCGGCTTGAACCAGGTGCGGCTGG
AAGGAGGCAGCACCAAAGCTAACTCGCTCCTAAGACTCTTGGAGGCGGGCACCTTCAAGAATCC
AAGTCACTGACTGAGCTGAGAGGTGGTACCTGCGGCTCTAACTAAAGGGTCTAATGATTTAGAA
ACCTTCCAATAACCTGTCCCCTCTCCGGTTCATCCCGAAGTCCACGGAAGCGTCACAGAACTCC
AAGAATTTCCTGAACTTCCCAGGTATCCTCCCTGGCTAAGGACTGGAAGTGGAGTGAACCTGGT
GGGAGACTTTGCGTCCGGGGGCTTGGGAGACACCTTCCAAACGCCTCCTCCTCGAGCATCCCAT
TCATCTCTGGGCAGCTTTACTGGCCGCCCCAAAAGCCAAAGCCTGCGCTCTTCTGAACTCTGCT
CTCATCTCTCCGTGGACATGGAACTACACGCCTGAAACCTGCTGGACCTTACTGGTTGTTTTGC
AAGACTCAGCTGCCAGAGAACGTGAACAATGAAGCTGCCACTTCTTCTGGCCCTGGTGGTCTGT
TCTGCAGTCAGTACAAATTTGAAGATGGTTTCAAAGAGAAATTCTGTGGATGGCTGCATCGATT
GGTCGGTGGATCTCAAGACCTACATGGCTTTGGCAGGTGAACCTGTCCGAGTGAAATGTGCGCT
TTTCTACAGTTATATCCGCACCAACTATAGCATGGCCCAGAGTACCGGGCTCCGGCTCATGTGG
TACAGAAACAAAGGGGACTTGGAAGAGCCCATCATCTTTTCAGAGGTCAGGATGAGCAAAGAGG
AAGATGCCATATGGTTTCACTCAGCTGAGGCACAAGACAGTGGATTCTACACTTGTGTTCTAAG
AAACTCCACATACTGCATGAAGGTGTCAATGTCCTTGACTGTTGCAGAGAATGAATCTGGCCTG
TGCTACAATAGCAGGATCCGCTACTTAGAGAAATCTGAAGTTACTAAACGAAAGGAGATCTCCT
GCCCAGACATGGATGACTTTAAGAAGTCTGATCAGGAACCTGATGTTGTATGGTACAAGGAATG
CAAGCCAAAAATGTGGAGAAGCATAATAATACAGAAGGGAAATGCTCTTCTCATCCAAGAAGTT
CAAGAAGAAGATGGAGGAAACTATACATGTGAACTTAAGTATGAAGGGAAACTTGTAAGGCGAA
CAACAGAATTAAAAGTTACAGCTTTACTCACAGACAAGCCTCCCAAGCCATTGTTCCCCATGGA
AAATCAGCCAAGTGTTATAGATGTCCAGCTGGGTAAACCTCTGAACATCCCTTGCAAAGCTTTC
TTTGGATTCAGTGGGGAGTCTGGACCAATGATCTACTGGATGAAAGGCGAGAAATTTATTGAAG
AATTGGCAGGTCACATTAGAGAAGGTGAAATAAGGCTCCTCAAAGAACATCTTGGAGAAAAAGA
AGTTGAATTGACCCTTATCTTTGACTCAGTGGTAGAAGCTGACTTGGCTAATTACACTTGCCAT
GTGGAAAACAGAAACGGACGGAAACATGCCAGTGTTTTACTTCGGAAAAAGGATTTAATCTACA
AAATTGAGCTTGCAGGGGGCCTGGGAGCAATCTTTCTGCTGCTTATACTGCTGCTGGTGGTCTA
CAAGTGCTACAACATAGAACTGATGCTTTTCTACCGACAGCGTTTTGGAGGTGATGAAACTACT
GATGACAACAAGGAATATGATGCATATCTCTCTTACACAAAAGTGGATCAAGATACTTTGGACT
GTGACAATACTGAGGAAGAGCAGTTTGCTCTTGAAATACTGCCAGATGTGCTAGAAAAACACTA
TGGATATAAACTCTTCATCCCAGAAAGGGATCTGATTCCAAGTGGAACATATATTGAAGATCTC
ACAAGATGTGTTGAGCAAAGCAGAAGACTTATTATCGTGCTAACTCCGGACTATATTCTCAGAC
GGGGATGGAGTATTTTCGAACTGGAAAGCAGACTCCATAACATGCTAGTCAGTGGAGAAATCAA
AGTGATTTTGATTGAGTGTACAGAATTAAAAGGGAAGGTGAATTGCCCGGAAGTGGAATCACTA
AAGCACAACATCAAACTTCTGTCACTGATCAAGTGGAAGGGACCCAAAAGCAGCAAGTTAAATT
CTAAGTTTTGGAAGCACTTAGTGTATGAAATGCCCATCAAGAAAAAAGAAATGCTATCCCACTG
CCATGTTCTAGACTCTGCAGAACAGGGGCTTTTTGGAGAGCTTCAGCCTATACCTTCCATTGCC
ATGACAAGTACCTCAGCCACAATGGTGCCATCGCAAGCTGATCTCCCTGAGTTCCACCATTCGG
ATTCAATGCAAATGAGGCACTGTTGCAGAGGATACAAACATGAGATGCCAGCCAACACCCTGTC
AGTACCCTCCTTAGGCAACCACCACACTTACTGTAACTTGCCACTAACACTACTCAATGGACAG
CTACCCCTTAATAATTCCTTAAAAGAGACTGAGGAACTTTCAAGGAACAATCCCTTACTACCAT
TATCATCCAAAGAGCTTAGCTTCACAAGTGATATTTGGTAGCAGAAAAAAAAAAAAAAACCCTC
AATTCCTCAGAACAACTAAATGAGAATATGAAATCTCTGCTACACTGAGAATAAATTACTCCTA
AAAACATTAAGGTGCTGAAACTGTGAAGAAAAAGGCACAACAACCATGTTTGTACTTAAATATT
TTATTTACCTTTATAGAATAGTAAGGGAATAAAAGGTCTTGTTTTTGTAGTGTGGCACCTTGTC
ACAATGTACAGATTTGATTTTTCCTGGAAAAAAAATTGAATTGTGTCTTTTCCAAGCAGGTTCT
ATGGCACCATATGATCTGCCCATATTTAGGAGTTTGGAATTTAAACAATATTTTTCATAAAA

hide sequence

RefSeq Acc Id:

XM_063279884 ⟹ XP_063135954

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	105,721,648 - 107,080,369 (+)	NCBI

RefSeq Acc Id:

XM_063279885 ⟹ XP_063135955

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	105,547,403 - 107,080,369 (+)	NCBI

RefSeq Acc Id:

XM_063279886 ⟹ XP_063135956

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	105,753,745 - 107,064,900 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001159814	(Get FASTA)	NCBI Sequence Viewer
	XP_063135954	(Get FASTA)	NCBI Sequence Viewer
	XP_063135955	(Get FASTA)	NCBI Sequence Viewer
	XP_063135956	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL88006	(Get FASTA)	NCBI Sequence Viewer
	EDL88007	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000076241
	ENSRNOP00000076241.1
	ENSRNOP00000102006.1

RefSeq Acc Id:	NP_001159814 ⟸ NM_001166342
- Peptide Label:	precursor
- UniProtKB:	A0A1W2Q6G2 (UniProtKB/TrEMBL), A6KNW2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKLPLLLALVVCSAVSTNLKMVSKRNSVDGCIDWSVDLKTYMALAGEPVRVKCALFYSYIRTNY SMAQSTGLRLMWYRNKGDLEEPIIFSEVRMSKEEDAIWFHSAEAQDSGFYTCVLRNSTYCMKVS MSLTVAENESGLCYNSRIRYLEKSEVTKRKEISCPDMDDFKKSDQEPDVVWYKECKPKMWRSII IQKGNALLIQEVQEEDGGNYTCELKYEGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQ LGKPLNIPCKAFFGFSGESGPMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELTLIFDS VVEADLANYTCHVENRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLILLLVVYKCYNIELML FYRQRFGGDETTDDNKEYDAYLSYTKVDQDTLDCDNTEEEQFALEILPDVLEKHYGYKLFIPER DLIPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIECTEL KGKVNCPEVESLKHNIKLLSLIKWKGPKSSKLNSKFWKHLVYEMPIKKKEMLSHCHVLDSAEQG LFGELQPIPSIAMTSTSATMVPSQADLPEFHHSDSMQMRHCCRGYKHEMPANTLSVPSLGNHHT YCNLPLTLLNGQLPLNNSLKETEELSRNNPLLPLSSKELSFTSDIW hide sequence

Ensembl Acc Id:

ENSRNOP00000076241 ⟸ ENSRNOT00000093348

RefSeq Acc Id:	XP_063135955 ⟸ XM_063279885
- Peptide Label:	isoform X1
- UniProtKB:	A6KNW2 (UniProtKB/TrEMBL), A0A1W2Q6G2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135954 ⟸ XM_063279884
- Peptide Label:	isoform X1
- UniProtKB:	A6KNW2 (UniProtKB/TrEMBL), A0A1W2Q6G2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063135956 ⟸ XM_063279886
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000102006 ⟸ ENSRNOT00000122842

Protein Domains

Ig-like TIR

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A1W2Q6G2-F1-model_v2	AlphaFold	A0A1W2Q6G2	1-686	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1561761	AgrOrtholog
BioCyc Gene	G2FUF-1579	BioCyc
Ensembl Genes	ENSRNOG00000062221	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000093348	ENTREZGENE
	ENSRNOT00000093348.3	UniProtKB/TrEMBL
	ENSRNOT00000122842.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
	3.40.50.10140	UniProtKB/TrEMBL
InterPro	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
	IL-1_rcpt_fam	UniProtKB/TrEMBL
	IL-1_rcpt_II-typ	UniProtKB/TrEMBL
	TIR_dom	UniProtKB/TrEMBL
	Toll_tir_struct_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:300913	UniProtKB/TrEMBL
NCBI Gene	300913	ENTREZGENE
PANTHER	PTHR11890	UniProtKB/TrEMBL
	X-LINKED INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN-LIKE 2	UniProtKB/TrEMBL
Pfam	I-set	UniProtKB/TrEMBL
	Ig_2	UniProtKB/TrEMBL
	TIR	UniProtKB/TrEMBL
PhenoGen	Il1rapl2	PhenoGen
PRINTS	INTRLEUKN1R2	UniProtKB/TrEMBL
	INTRLKN1R1F	UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/TrEMBL
	TIR	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000062221	RatGTEx
SMART	IGc2	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
	TIR	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
	SSF52200	UniProtKB/TrEMBL
UniProt	A0A1W2Q6G2	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L9M7_RAT	UniProtKB/TrEMBL
	A6KNW2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Il1rapl2	interleukin 1 receptor accessory protein-like 2	Il1rapl2_predicted	interleukin 1 receptor accessory protein-like 2 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Il1rapl2_predicted	interleukin 1 receptor accessory protein-like 2 (predicted)	RGD1561761_predicted	similar to TIGIRR-1 (predicted)	Symbol and Name updated	1299863	APPROVED
2006-03-07	RGD1561761_predicted	similar to TIGIRR-1 (predicted)	LOC300913	similar to TIGIRR-1	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC300913	similar to TIGIRR-1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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