Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nudt16l1 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NUDT16L1 mRNA] | CTD | PMID:31150632 | Nudt16l1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Nudt16l1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NUDT16L1 mRNA | CTD | PMID:22206623 | Nudt16l1 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Nudt16l1 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Nudt16l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUDT16L1 mRNA | CTD | PMID:25270620 | Nudt16l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NUDT16L1 mRNA | CTD | PMID:32109520 | Nudt16l1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NUDT16L1 mRNA | CTD | PMID:21570461 | Nudt16l1 | Rat | acrolein | multiple interactions | ISO | NUDT16L1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NUDT16L1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of NUDT16L1 mRNA | CTD | PMID:32699268 | Nudt16l1 | Rat | all-trans-retinoic acid | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of NUDT16L1 mRNA | CTD | PMID:23724009 | Nudt16l1 | Rat | alpha-pinene | multiple interactions | ISO | NUDT16L1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NUDT16L1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of NUDT16L1 mRNA | CTD | PMID:32699268 | Nudt16l1 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of NUDT16L1 mRNA | CTD | PMID:35163327 | Nudt16l1 | Rat | aristolochic acid A | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of NUDT16L1 mRNA | CTD | PMID:33212167 | Nudt16l1 | Rat | Aroclor 1254 | increases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of NUDT16L1 mRNA | CTD | PMID:23650126 | Nudt16l1 | Rat | benzo[a]pyrene | increases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of NUDT16L1 mRNA | CTD | PMID:22228805 | Nudt16l1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NUDT16L1 mRNA | CTD | PMID:25181051 | Nudt16l1 | Rat | bisphenol A | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of NUDT16L1 mRNA | CTD | PMID:35598803 | Nudt16l1 | Rat | bisphenol A | decreases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of NUDT16L1 protein | CTD | PMID:31675489 | Nudt16l1 | Rat | bisphenol A | increases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of NUDT16L1 mRNA | CTD | PMID:33221593 | Nudt16l1 | Rat | cadmium atom | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Cadmium results in increased expression of NUDT16L1 mRNA | CTD | PMID:24376830 | Nudt16l1 | Rat | chlorpyrifos | increases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of NUDT16L1 mRNA | CTD | PMID:37019170 | Nudt16l1 | Rat | clofibrate | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of NUDT16L1 mRNA | CTD | PMID:23811191 | Nudt16l1 | Rat | copper(II) sulfate | decreases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of NUDT16L1 mRNA | CTD | PMID:19549813 | Nudt16l1 | Rat | crocidolite asbestos | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of NUDT16L1 mRNA | CTD | PMID:29279043 | Nudt16l1 | Rat | cyclosporin A | decreases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of NUDT16L1 mRNA | CTD | PMID:20106945 | Nudt16l1 | Rat | cylindrospermopsin | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of NUDT16L1 mRNA | CTD | PMID:24921660 | Nudt16l1 | Rat | decabromodiphenyl ether | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | decabromobiphenyl ether results in increased expression of NUDT16L1 protein | CTD | PMID:31675489 | Nudt16l1 | Rat | Dibutyl phosphate | affects expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of NUDT16L1 mRNA | CTD | PMID:37042841 | Nudt16l1 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of NUDT16L1 mRNA | CTD | PMID:21266533 | Nudt16l1 | Rat | dibutyl phthalate | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of NUDT16L1 mRNA | CTD | PMID:17361019 and PMID:21266533 | Nudt16l1 | Rat | doxorubicin | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of NUDT16L1 mRNA | CTD | PMID:29803840 | Nudt16l1 | Rat | enzyme inhibitor | multiple interactions | ISO | NUDT16L1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of NUDT16L1 protein | CTD | PMID:23301498 | Nudt16l1 | Rat | ethanol | increases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Ethanol results in increased expression of NUDT16L1 mRNA | CTD | PMID:30319688 | Nudt16l1 | Rat | ethanol | affects expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Ethanol affects the expression of NUDT16L1 mRNA | CTD | PMID:30319688 | Nudt16l1 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of NUDT16L1 mRNA | CTD | PMID:24136188 | Nudt16l1 | Rat | fluoranthene | multiple interactions | ISO | Nudt16l1 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of NUDT16L1 mRNA | CTD | PMID:28329830 | Nudt16l1 | Rat | folic acid | multiple interactions | ISO | Nudt16l1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NUDT16L1 mRNA | CTD | PMID:22206623 | Nudt16l1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of NUDT16L1 mRNA | CTD | PMID:22061828 | Nudt16l1 | Rat | ivermectin | decreases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of NUDT16L1 protein | CTD | PMID:32959892 | Nudt16l1 | Rat | mercury dichloride | decreases expression | EXP | | 6480464 | Mercuric Chloride results in decreased expression of NUDT16L1 mRNA | CTD | PMID:16507785 | Nudt16l1 | Rat | methyl methanesulfonate | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of NUDT16L1 mRNA | CTD | PMID:23649840 | Nudt16l1 | Rat | ozone | multiple interactions | ISO | NUDT16L1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of NUDT16L1 mRNA more ... | CTD | PMID:32699268 | Nudt16l1 | Rat | paracetamol | affects expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NUDT16L1 mRNA | CTD | PMID:17562736 | Nudt16l1 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of NUDT16L1 mRNA | CTD | PMID:35163327 | Nudt16l1 | Rat | pirinixic acid | multiple interactions | ISO | NUDT16L1 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of NUDT16L1 mRNA | CTD | PMID:19710929 | Nudt16l1 | Rat | pirinixic acid | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of NUDT16L1 mRNA | CTD | PMID:17426115 | Nudt16l1 | Rat | resveratrol | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | resveratrol results in decreased expression of NUDT16L1 protein | CTD | PMID:25505154 | Nudt16l1 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of NUDT16L1 mRNA | CTD | PMID:19281266 | Nudt16l1 | Rat | sulindac | increases expression | EXP | | 6480464 | Sulindac results in increased expression of NUDT16L1 mRNA | CTD | PMID:24136188 | Nudt16l1 | Rat | sunitinib | decreases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of NUDT16L1 mRNA | CTD | PMID:31533062 | Nudt16l1 | Rat | temozolomide | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of NUDT16L1 mRNA | CTD | PMID:31758290 | Nudt16l1 | Rat | testosterone | decreases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of NUDT16L1 mRNA | CTD | PMID:33359661 | Nudt16l1 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NUDT16L1 mRNA] | CTD | PMID:31150632 | Nudt16l1 | Rat | tetrachloromethane | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of NUDT16L1 mRNA | CTD | PMID:31919559 | Nudt16l1 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of NUDT16L1 mRNA | CTD | PMID:31150632 | Nudt16l1 | Rat | thapsigargin | decreases expression | ISO | Nudt16l1 (Mus musculus) | 6480464 | Thapsigargin results in decreased expression of NUDT16L1 protein | CTD | PMID:24648495 | Nudt16l1 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of NUDT16L1 mRNA | CTD | PMID:34492290 | Nudt16l1 | Rat | thiram | increases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Thiram results in increased expression of NUDT16L1 mRNA | CTD | PMID:38568856 | Nudt16l1 | Rat | titanium dioxide | decreases methylation | ISO | Nudt16l1 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of NUDT16L1 gene | CTD | PMID:35295148 | Nudt16l1 | Rat | triphenyl phosphate | affects expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of NUDT16L1 mRNA | CTD | PMID:37042841 | Nudt16l1 | Rat | valproic acid | increases methylation | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of NUDT16L1 gene | CTD | PMID:29154799 | Nudt16l1 | Rat | valproic acid | decreases expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NUDT16L1 mRNA | CTD | PMID:23179753 and PMID:27188386 | Nudt16l1 | Rat | valproic acid | affects expression | ISO | NUDT16L1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of NUDT16L1 mRNA | CTD | PMID:25979313 | Nudt16l1 | Rat | zinc atom | multiple interactions | ISO | NUDT16L1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of NUDT16L1 mRNA | CTD | PMID:18593933 | Nudt16l1 | Rat | zinc(0) | multiple interactions | ISO | NUDT16L1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of NUDT16L1 mRNA | CTD | PMID:18593933 | |