Srsf4 (serine and arginine rich splicing factor 4) - Rat Genome Database

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Gene: Srsf4 (serine and arginine rich splicing factor 4) Rattus norvegicus
Analyze
Symbol: Srsf4
Name: serine and arginine rich splicing factor 4
RGD ID: 1561347
Description: Enables sequence-specific mRNA binding activity. Involved in response to insulin. Predicted to be located in nuclear speck. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRSF4 (serine and arginine rich splicing factor 4); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 17beta-estradiol; bisphenol A; buspirone.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362612; RGD1561347; serine/arginine-rich splicing factor 4; Sfrs4; similar to Sfrs4 protein; splicing factor, arginine/serine-rich 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85149,345,538 - 149,373,309 (+)NCBIGRCr8
mRatBN7.25144,060,981 - 144,090,798 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5144,061,463 - 144,089,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5146,766,904 - 146,794,813 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05148,536,752 - 148,564,663 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05148,525,380 - 148,553,198 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05150,032,999 - 150,060,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5150,032,999 - 150,060,765 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05153,711,721 - 153,739,491 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45150,731,169 - 150,758,934 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5142,505,197 - 142,532,845 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes expands the catalog of participating factors. Chen YI, etal., Nucleic Acids Res. 2007;35(12):3928-44. Epub 2007 May 30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Altered expression of heterogenous nuclear ribonucleoproteins and SR factors in human colon adenocarcinomas. Ghigna C, etal., Cancer Res. 1998 Dec 15;58(24):5818-24.
4. Aberrant expression of splicing factors in newly diagnosed acute myeloid leukemia. Liu J, etal., Onkologie. 2012;35(6):335-40. doi: 10.1159/000338941. Epub 2012 May 22.
5. Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells. Patel NA, etal., J Biol Chem. 2001 Jun 22;276(25):22648-54. Epub 2001 Mar 30.
6. Disturbed expression of splicing factors in renal cancer affects alternative splicing of apoptosis regulators, oncogenes, and tumor suppressors. Piekielko-Witkowska A, etal., PLoS One. 2010 Oct 27;5(10):e13690. doi: 10.1371/journal.pone.0013690.
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Proteomic analysis of amniotic fluid in pregnancies with Down syndrome. Tsangaris GT, etal., Proteomics. 2006 Aug;6(15):4410-9.
11. The spliceosome: design principles of a dynamic RNP machine. Wahl MC, etal., Cell. 2009 Feb 20;136(4):701-18. doi: 10.1016/j.cell.2009.02.009.
12. Serine arginine splicing factor 3 is involved in enhanced splicing of glucose-6-phosphate dehydrogenase RNA in response to nutrients and hormones in liver. Walsh CM, etal., J Biol Chem. 2013 Jan 25;288(4):2816-28. doi: 10.1074/jbc.M112.410803. Epub 2012 Dec 11.
Additional References at PubMed
PMID:12477932   PMID:15009664   PMID:21073651   PMID:22658674   PMID:22681889   PMID:24029230   PMID:25002582   PMID:25931508  


Genomics

Comparative Map Data
Srsf4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85149,345,538 - 149,373,309 (+)NCBIGRCr8
mRatBN7.25144,060,981 - 144,090,798 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5144,061,463 - 144,089,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5146,766,904 - 146,794,813 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05148,536,752 - 148,564,663 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05148,525,380 - 148,553,198 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05150,032,999 - 150,060,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5150,032,999 - 150,060,765 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05153,711,721 - 153,739,491 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45150,731,169 - 150,758,934 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5142,505,197 - 142,532,845 (+)NCBICelera
Cytogenetic Map5q36NCBI
SRSF4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38129,147,743 - 29,181,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl129,147,743 - 29,181,900 (-)EnsemblGRCh38hg38GRCh38
GRCh37129,474,255 - 29,508,412 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36129,346,946 - 29,380,948 (-)NCBINCBI36Build 36hg18NCBI36
Build 34129,294,980 - 29,328,977NCBI
Celera127,870,392 - 27,904,789 (-)NCBICelera
Cytogenetic Map1p35.3NCBI
HuRef127,726,138 - 27,760,578 (-)NCBIHuRef
CHM1_1129,589,632 - 29,624,036 (-)NCBICHM1_1
T2T-CHM13v2.0128,990,399 - 29,024,556 (-)NCBIT2T-CHM13v2.0
Srsf4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394131,600,841 - 131,629,036 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4131,600,928 - 131,629,017 (+)EnsemblGRCm39 Ensembl
GRCm384131,873,530 - 131,901,725 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4131,873,617 - 131,901,706 (+)EnsemblGRCm38mm10GRCm38
MGSCv374131,429,554 - 131,457,640 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364131,169,807 - 131,173,781 (+)NCBIMGSCv36mm8
Celera4130,034,138 - 130,062,224 (+)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map464.53NCBI
Srsf4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554528,142,500 - 8,174,869 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554528,143,850 - 8,174,830 (-)NCBIChiLan1.0ChiLan1.0
SRSF4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21197,661,303 - 197,695,492 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11196,780,466 - 196,814,798 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0128,418,297 - 28,452,595 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1129,444,263 - 29,490,360 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl129,444,269 - 29,478,035 (-)Ensemblpanpan1.1panPan2
SRSF4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,418,626 - 71,434,140 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,394,037 - 71,471,997 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha267,983,412 - 68,010,251 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0271,967,829 - 71,993,683 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1268,796,130 - 68,822,742 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0269,803,922 - 69,830,460 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0270,801,912 - 70,828,510 (+)NCBIUU_Cfam_GSD_1.0
Srsf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505847,288,456 - 47,315,957 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647413,113,867 - 13,140,599 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647413,113,191 - 13,140,956 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRSF4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120103,641,650 - 103,674,066 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20103,642,150 - 103,673,391 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603312,855,849 - 12,888,333 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srsf4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476412,916,858 - 12,946,238 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476412,916,857 - 12,945,861 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Srsf4
147 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:68
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000013301
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat

Markers in Region
AW550192  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25144,088,647 - 144,088,786 (+)MAPPERmRatBN7.2
Rnor_6.05150,060,182 - 150,060,320NCBIRnor6.0
Rnor_5.05153,738,904 - 153,739,042UniSTSRnor5.0
RGSC_v3.45150,758,353 - 150,758,491UniSTSRGSC3.4
Celera5142,532,258 - 142,532,396UniSTS
Cytogenetic Map5q36UniSTS
BF394391  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25144,067,672 - 144,067,762 (+)MAPPERmRatBN7.2
Rnor_6.05150,039,209 - 150,039,298NCBIRnor6.0
Rnor_5.05153,717,931 - 153,718,020UniSTSRnor5.0
RGSC_v3.45151,146,572 - 151,146,661UniSTSRGSC3.4
RGSC_v3.45150,737,379 - 150,737,468UniSTSRGSC3.4
Celera5142,511,407 - 142,511,496UniSTS
RH 3.4 Map5988.8UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 57 41 19 41 1 4 74 34 41 11 1
Low 7 7 7 1 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000013301   ⟹   ENSRNOP00000013301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,061,463 - 144,089,229 (+)Ensembl
Rnor_6.0 Ensembl5150,032,999 - 150,060,765 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000108926   ⟹   ENSRNOP00000079743
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,061,900 - 144,089,229 (+)Ensembl
RefSeq Acc Id: NM_001108685   ⟹   NP_001102155
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,345,538 - 149,373,309 (+)NCBI
mRatBN7.25144,061,463 - 144,089,235 (+)NCBI
Rnor_6.05150,032,999 - 150,060,769 (+)NCBI
Rnor_5.05153,711,721 - 153,739,491 (+)NCBI
RGSC_v3.45150,731,169 - 150,758,934 (+)RGD
Celera5142,505,197 - 142,532,845 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001102155 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI60850 (Get FASTA)   NCBI Sequence Viewer  
  EDL80612 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013301
  ENSRNOP00000013301.4
  ENSRNOP00000079743.1
Reference Protein Sequences
RefSeq Acc Id: NP_001102155   ⟸   NM_001108685
- UniProtKB: G3V798 (UniProtKB/TrEMBL),   A6ISR1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000013301   ⟸   ENSRNOT00000013301
RefSeq Acc Id: ENSRNOP00000079743   ⟸   ENSRNOT00000108926
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V798-F1-model_v2 AlphaFold G3V798 1-488 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694090
Promoter ID:EPDNEW_R4614
Type:initiation region
Name:Srsf4_1
Description:serine and arginine rich splicing factor 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05150,032,983 - 150,033,043EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561347 AgrOrtholog
BioCyc Gene G2FUF-39719 BioCyc
Ensembl Genes ENSRNOG00000010007 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013301 ENTREZGENE
  ENSRNOT00000013301.6 UniProtKB/TrEMBL
  ENSRNOT00000108926.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:8363821 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM2_SRSF4-like UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
KEGG Report rno:362612 UniProtKB/TrEMBL
MGC_CLONE MGC:187592 IMAGE-MGC_LOAD
NCBI Gene 362612 ENTREZGENE
PANTHER RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  SERINE/ARGININE-RICH SPLICING FACTOR 4 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen Srsf4 PhenoGen
PROSITE RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010007 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8I5ZP75_RAT UniProtKB/TrEMBL
  A6ISR1 ENTREZGENE, UniProtKB/TrEMBL
  B1H240_RAT UniProtKB/TrEMBL
  G3V798 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-15 Srsf4  serine and arginine rich splicing factor 4  Srsf4  serine/arginine-rich splicing factor 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-08-01 Srsf4  serine/arginine-rich splicing factor 4  Sfrs4  splicing factor, arginine/serine-rich 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-22 Sfrs4  splicing factor, arginine/serine-rich 4  Srsf4  serine/arginine-rich splicing factor 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-07-13 Srsf4  serine/arginine-rich splicing factor 4  Sfrs4  splicing factor, arginine/serine-rich 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Sfrs4  splicing factor, arginine/serine-rich 4  RGD1561347  similar to Sfrs4 protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561347  similar to Sfrs4 protein   RGD1561347_predicted  similar to Sfrs4 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561347_predicted  similar to Sfrs4 protein (predicted)  LOC362612  similar to Sfrs4 protein  Symbol and Name status set to approved 1299863 APPROVED