Mdm1 (Mdm1 nuclear protein) - Rat Genome Database

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Pathways
Gene: Mdm1 (Mdm1 nuclear protein) Rattus norvegicus
Analyze
Symbol: Mdm1
Name: Mdm1 nuclear protein
RGD ID: 1561092
Description: Predicted to enable microtubule binding activity. Predicted to be involved in negative regulation of centriole replication and retina development in camera-type eye. Predicted to be located in microtubule organizing center; non-motile cilium; and nucleus. Orthologous to human MDM1 (Mdm1 nuclear protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC314859; Mdm1 nuclear protein homolog; Mdm1 nuclear protein homolog (mouse); nuclear protein MDM1; similar to transformed mouse 3T3 cell double minute 1; transformed mouse 3T3 cell double minute 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8755,615,459 - 55,651,889 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl755,615,608 - 55,651,888 (+)EnsemblGRCr8
mRatBN7.2753,729,603 - 53,766,034 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl753,729,610 - 53,766,034 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx755,646,237 - 55,672,740 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0757,849,342 - 57,875,845 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0757,627,185 - 57,653,689 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0761,165,652 - 61,200,865 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl761,165,640 - 61,200,879 (+)Ensemblrn6Rnor6.0
Rnor_5.0761,161,294 - 61,197,124 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4757,455,598 - 57,482,092 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera750,507,908 - 50,534,254 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
azathioprine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
furan  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
pentanal  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
testosterone  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
centriolar satellite  (IEA,ISO)
centriole  (IEA,ISO,ISS)
centrosome  (IEA,ISO,ISS)
microtubule  (IEA)
non-motile cilium  (ISO)
nucleus  (IEA,ISO,ISS)

Molecular Function
microtubule binding  (IEA,ISO,ISS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Age-related retinal degeneration (arrd2) in a novel mouse model due to a nonsense mutation in the Mdm1 gene. Chang B, etal., Hum Mol Genet. 2008 Dec 15;17(24):3929-41. doi: 10.1093/hmg/ddn295. Epub 2008 Sep 18.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:21052544   PMID:23300604   PMID:26337392  


Genomics

Comparative Map Data
Mdm1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8755,615,459 - 55,651,889 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl755,615,608 - 55,651,888 (+)EnsemblGRCr8
mRatBN7.2753,729,603 - 53,766,034 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl753,729,610 - 53,766,034 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx755,646,237 - 55,672,740 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0757,849,342 - 57,875,845 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0757,627,185 - 57,653,689 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0761,165,652 - 61,200,865 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl761,165,640 - 61,200,879 (+)Ensemblrn6Rnor6.0
Rnor_5.0761,161,294 - 61,197,124 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4757,455,598 - 57,482,092 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera750,507,908 - 50,534,254 (+)NCBICelera
Cytogenetic Map7q22NCBI
MDM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381268,294,566 - 68,332,362 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1268,272,443 - 68,332,381 (-)Ensemblhg38GRCh38
GRCh371268,688,346 - 68,726,142 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361266,974,613 - 67,012,379 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341267,005,167 - 67,012,350NCBI
Celera1268,352,374 - 68,390,189 (-)NCBICelera
Cytogenetic Map12q15NCBI
HuRef1265,739,499 - 65,777,306 (-)NCBIHuRef
CHM1_11268,656,328 - 68,694,144 (-)NCBICHM1_1
T2T-CHM13v2.01268,274,117 - 68,311,913 (-)NCBIT2T-CHM13v2.0
Mdm1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910117,977,446 - 118,004,904 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10117,977,716 - 118,004,902 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3810118,141,540 - 118,168,999 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10118,141,811 - 118,168,997 (+)Ensemblmm10GRCm38
MGSCv3710117,578,843 - 117,606,055 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610117,544,825 - 117,571,990 (+)NCBIMGSCv36mm8
Celera10120,092,487 - 120,120,063 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1066.65NCBI
Mdm1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545814,780,437 - 14,822,954 (-)Ensembl
ChiLan1.0NW_00495545814,789,842 - 14,823,117 (-)NCBIChiLan1.0ChiLan1.0
MDM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21076,310,352 - 76,348,641 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11276,306,749 - 76,345,038 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01265,803,548 - 65,841,404 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11268,588,541 - 68,626,359 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1268,588,541 - 68,626,326 (-)EnsemblpanPan2panpan1.1
MDM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11010,523,656 - 10,552,824 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1010,524,328 - 10,696,181 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1010,456,983 - 10,486,143 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01010,647,765 - 10,676,917 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1010,647,770 - 10,676,899 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11010,515,759 - 10,544,917 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01010,762,218 - 10,791,382 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01010,884,769 - 10,913,942 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mdm1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494547,815,517 - 47,848,237 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365456,261,875 - 6,294,621 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365456,261,887 - 6,294,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MDM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl532,640,945 - 32,673,638 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1532,640,939 - 32,673,624 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2535,453,845 - 35,486,488 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MDM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11163,926,950 - 64,082,149 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1163,927,640 - 63,965,097 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037181,740,938 - 181,779,219 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mdm1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248022,648 - 9,999 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mdm1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11196,236,577 - 196,262,850 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mdm1
819 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:159
Count of miRNA genes:110
Interacting mature miRNAs:140
Transcripts:ENSRNOT00000048765
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74913799967614020Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)74968283263890004Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
2303629Vencon3Ventilatory control QTL 37.25respiration trait (VT:0001943)respiration rate (CMO:0000289)74299622658678836Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71746044762460447Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)72005723265057232Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat

Markers in Region
RH136966  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2753,765,803 - 53,765,963 (+)MAPPERmRatBN7.2
Rnor_6.0761,200,635 - 61,200,794NCBIRnor6.0
Rnor_5.0761,196,894 - 61,197,053UniSTSRnor5.0
RGSC_v3.4757,481,862 - 57,482,021UniSTSRGSC3.4
Celera750,534,024 - 50,534,183UniSTS
RH 3.4 Map7482.2UniSTS
Cytogenetic Map7q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001017459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006241388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC087101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB544747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV126474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000048765   ⟹   ENSRNOP00000041359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl755,625,167 - 55,651,887 (+)Ensembl
mRatBN7.2 Ensembl753,739,532 - 53,766,032 (+)Ensembl
Rnor_6.0 Ensembl761,174,369 - 61,200,863 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087955   ⟹   ENSRNOP00000075623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl755,615,608 - 55,651,887 (+)Ensembl
mRatBN7.2 Ensembl753,729,610 - 53,766,034 (+)Ensembl
Rnor_6.0 Ensembl761,165,640 - 61,200,879 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091885   ⟹   ENSRNOP00000071496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl755,625,380 - 55,651,887 (+)Ensembl
mRatBN7.2 Ensembl753,739,532 - 53,766,032 (+)Ensembl
Rnor_6.0 Ensembl761,174,401 - 61,200,863 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108196   ⟹   ENSRNOP00000091573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl755,625,379 - 55,651,065 (+)Ensembl
mRatBN7.2 Ensembl753,739,532 - 53,765,210 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114732   ⟹   ENSRNOP00000077918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl755,625,379 - 55,630,935 (+)Ensembl
mRatBN7.2 Ensembl753,739,532 - 53,745,080 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118906   ⟹   ENSRNOP00000081317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl755,625,108 - 55,651,888 (+)Ensembl
mRatBN7.2 Ensembl753,739,265 - 53,766,034 (+)Ensembl
RefSeq Acc Id: NM_001017459   ⟹   NP_001017459
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,625,388 - 55,651,889 (+)NCBI
mRatBN7.2753,739,532 - 53,766,034 (+)NCBI
Rnor_6.0761,174,369 - 61,200,865 (+)NCBI
Rnor_5.0761,161,294 - 61,197,124 (+)NCBI
RGSC_v3.4757,455,598 - 57,482,092 (+)RGD
Celera750,507,908 - 50,534,254 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241385   ⟹   XP_006241447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,625,364 - 55,651,889 (+)NCBI
mRatBN7.2753,739,500 - 53,766,034 (+)NCBI
Rnor_6.0761,174,340 - 61,200,865 (+)NCBI
Rnor_5.0761,161,294 - 61,197,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241387   ⟹   XP_006241449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,624,837 - 55,651,889 (+)NCBI
mRatBN7.2753,739,280 - 53,766,034 (+)NCBI
Rnor_6.0761,174,158 - 61,200,865 (+)NCBI
Rnor_5.0761,161,294 - 61,197,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006241388   ⟹   XP_006241450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,625,365 - 55,651,889 (+)NCBI
mRatBN7.2753,739,502 - 53,766,034 (+)NCBI
Rnor_6.0761,174,340 - 61,200,865 (+)NCBI
Rnor_5.0761,161,294 - 61,197,124 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008765400   ⟹   XP_008763622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,459 - 55,651,889 (+)NCBI
mRatBN7.2753,729,603 - 53,766,034 (+)NCBI
Rnor_6.0761,165,652 - 61,200,865 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079129   ⟹   XP_038935057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,634,195 - 55,651,889 (+)NCBI
mRatBN7.2753,749,240 - 53,766,034 (+)NCBI
RefSeq Acc Id: XM_063263489   ⟹   XP_063119559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,485 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263490   ⟹   XP_063119560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,625,364 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263491   ⟹   XP_063119561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,485 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263492   ⟹   XP_063119562
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,459 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263493   ⟹   XP_063119563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,624,837 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263494   ⟹   XP_063119564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,485 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263495   ⟹   XP_063119565
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,624,837 - 55,651,889 (+)NCBI
RefSeq Acc Id: XM_063263496   ⟹   XP_063119566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8755,615,485 - 55,651,889 (+)NCBI
RefSeq Acc Id: NP_001017459   ⟸   NM_001017459
- UniProtKB: Q5PQN4 (UniProtKB/Swiss-Prot),   A6IGU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241449   ⟸   XM_006241387
- Peptide Label: isoform X3
- UniProtKB: A6IGU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241447   ⟸   XM_006241385
- Peptide Label: isoform X1
- UniProtKB: A6IGU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006241450   ⟸   XM_006241388
- Peptide Label: isoform X4
- UniProtKB: A6IGU6 (UniProtKB/TrEMBL),   A6IGU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763622   ⟸   XM_008765400
- Peptide Label: isoform X2
- UniProtKB: A6IGU8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075623   ⟸   ENSRNOT00000087955
Ensembl Acc Id: ENSRNOP00000041359   ⟸   ENSRNOT00000048765
Ensembl Acc Id: ENSRNOP00000071496   ⟸   ENSRNOT00000091885
RefSeq Acc Id: XP_038935057   ⟸   XM_039079129
- Peptide Label: isoform X11
Ensembl Acc Id: ENSRNOP00000081317   ⟸   ENSRNOT00000118906
Ensembl Acc Id: ENSRNOP00000091573   ⟸   ENSRNOT00000108196
Ensembl Acc Id: ENSRNOP00000077918   ⟸   ENSRNOT00000114732
RefSeq Acc Id: XP_063119562   ⟸   XM_063263492
- Peptide Label: isoform X6
- UniProtKB: A0A0G2KB24 (UniProtKB/TrEMBL),   A6IGU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119566   ⟸   XM_063263496
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063119559   ⟸   XM_063263489
- Peptide Label: isoform X2
- UniProtKB: A6IGU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119561   ⟸   XM_063263491
- Peptide Label: isoform X6
- UniProtKB: A0A0G2KB24 (UniProtKB/TrEMBL),   A6IGU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119564   ⟸   XM_063263494
- Peptide Label: isoform X8
- UniProtKB: A6IGU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119563   ⟸   XM_063263493
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZUT4 (UniProtKB/TrEMBL),   A6IGU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119565   ⟸   XM_063263495
- Peptide Label: isoform X9
- UniProtKB: A6IGU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119560   ⟸   XM_063263490
- Peptide Label: isoform X5
- UniProtKB: A6IGU8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PQN4-F1-model_v2 AlphaFold Q5PQN4 1-719 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695225
Promoter ID:EPDNEW_R5744
Type:initiation region
Name:Mdm1_1
Description:Mdm1 nuclear protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0761,174,446 - 61,174,506EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561092 AgrOrtholog
BioCyc Gene G2FUF-33945 BioCyc
Ensembl Genes ENSRNOG00000007286 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000048765 ENTREZGENE
  ENSRNOT00000048765.6 UniProtKB/Swiss-Prot
  ENSRNOT00000087955 ENTREZGENE
  ENSRNOT00000108196 ENTREZGENE
  ENSRNOT00000118906 ENTREZGENE
IMAGE_CLONE IMAGE:7192579 IMAGE-MGC_LOAD
InterPro MDM1 UniProtKB/Swiss-Prot
KEGG Report rno:314859 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94684 IMAGE-MGC_LOAD
NCBI Gene 314859 ENTREZGENE
PANTHER NUCLEAR PROTEIN MDM1 UniProtKB/Swiss-Prot
  PTHR32078 UniProtKB/Swiss-Prot
Pfam MDM1 UniProtKB/Swiss-Prot
PhenoGen Mdm1 PhenoGen
RatGTEx ENSRNOG00000007286 RatGTEx
UniProt A0A0G2K0L7_RAT UniProtKB/TrEMBL
  A0A0G2KB24 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5YCK2_RAT UniProtKB/TrEMBL
  A0A8I5ZUT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJR7_RAT UniProtKB/TrEMBL
  A6IGU6 ENTREZGENE, UniProtKB/TrEMBL
  A6IGU8 ENTREZGENE, UniProtKB/TrEMBL
  MDM1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-26 Mdm1  Mdm1 nuclear protein  Mdm1  Mdm1 nuclear protein homolog (mouse)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-24 Mdm1  Mdm1 nuclear protein homolog (mouse)  Mdm1  transformed mouse 3T3 cell double minute 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Mdm1  transformed mouse 3T3 cell double minute 1  LOC314859  similar to transformed mouse 3T3 cell double minute 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC314859  similar to transformed mouse 3T3 cell double minute 1      Symbol and Name status set to provisional 70820 PROVISIONAL