Mettl8 (methyltransferase 8, tRNA N3-cytidine) - Rat Genome Database

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Gene: Mettl8 (methyltransferase 8, tRNA N3-cytidine) Rattus norvegicus
Analyze
Symbol: Mettl8
Name: methyltransferase 8, tRNA N3-cytidine
RGD ID: 1561059
Description: Predicted to enable histone acetyltransferase activity; mRNA methyltransferase activity; and tRNA (cytidine-3-)-methyltransferase activity. Predicted to be involved in RNA metabolic process and positive regulation of mitochondrial translation. Predicted to act upstream of or within fat cell differentiation and skeletal muscle tissue development. Predicted to be located in cytoplasm and nucleus. Predicted to be active in mitochondrial matrix. Orthologous to human METTL8 (methyltransferase 8, tRNA N3-cytidine); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; copper atom.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AABR07052486.1; LOC502633; methyltransferase 8, methylcytidine; methyltransferase like 8; methyltransferase-like protein 8; mRNA N(3)-methylcytidine methyltransferase METTL8; RGD1561059; similar to BC004636 protein; tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8376,140,465 - 76,271,367 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl376,144,178 - 76,271,400 (-)EnsemblGRCr8
mRatBN7.2355,731,453 - 55,863,652 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl355,770,167 - 55,863,676 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx359,167,776 - 59,261,627 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0367,751,350 - 67,845,196 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0365,514,225 - 65,607,442 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0357,257,394 - 57,642,096 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl357,257,394 - 57,646,610 (-)NCBIrn6Rnor6.0
Rnor_5.0364,067,269 - 64,142,322 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0363,739,467 - 63,753,417 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4353,215,940 - 53,310,137 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera355,318,933 - 55,411,758 (-)NCBICelera
Cytogenetic Map3q22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15992539   PMID:28655767   PMID:34800366  


Genomics

Comparative Map Data
Mettl8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8376,140,465 - 76,271,367 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl376,144,178 - 76,271,400 (-)EnsemblGRCr8
mRatBN7.2355,731,453 - 55,863,652 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl355,770,167 - 55,863,676 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx359,167,776 - 59,261,627 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0367,751,350 - 67,845,196 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0365,514,225 - 65,607,442 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0357,257,394 - 57,642,096 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl357,257,394 - 57,646,610 (-)NCBIrn6Rnor6.0
Rnor_5.0364,067,269 - 64,142,322 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0363,739,467 - 63,753,417 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4353,215,940 - 53,310,137 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera355,318,933 - 55,411,758 (-)NCBICelera
Cytogenetic Map3q22NCBI
METTL8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382171,315,746 - 171,434,772 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2171,315,746 - 171,434,802 (-)Ensemblhg38GRCh38
GRCh372172,172,256 - 172,291,282 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362171,888,007 - 171,998,865 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2165,790,476 - 165,907,900 (-)NCBICelera
Cytogenetic Map2q31.1NCBI
HuRef2164,059,509 - 164,176,804 (-)NCBIHuRef
CHM1_12172,180,433 - 172,298,093 (-)NCBICHM1_1
T2T-CHM13v2.02171,792,877 - 171,911,912 (-)NCBIT2T-CHM13v2.0
Mettl8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39270,794,902 - 70,886,729 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl270,794,905 - 70,885,927 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38270,964,561 - 71,056,388 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl270,964,561 - 71,055,583 (-)Ensemblmm10GRCm38
MGSCv37270,802,618 - 70,893,663 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36270,765,400 - 70,856,366 (-)NCBIMGSCv36mm8
Celera272,632,432 - 72,724,286 (-)NCBICelera
Cytogenetic Map2C2NCBI
cM Map242.34NCBI
Mettl8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554493,490,568 - 3,533,584 (+)Ensembl
ChiLan1.0NW_0049554493,458,683 - 3,534,377 (+)NCBIChiLan1.0ChiLan1.0
METTL8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21373,987,487 - 74,113,869 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B74,008,563 - 74,128,842 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B58,605,042 - 58,725,999 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B176,070,609 - 176,183,862 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B176,070,609 - 176,183,862 (-)EnsemblpanPan2panpan1.1
METTL8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13615,816,518 - 15,906,019 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3615,819,138 - 15,905,064 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3615,826,849 - 15,916,386 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03615,939,707 - 16,029,316 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3615,942,170 - 16,028,784 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13616,025,454 - 16,115,010 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03616,025,261 - 16,114,815 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03616,127,954 - 16,217,507 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mettl8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303133,037,469 - 133,124,784 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365091,591,348 - 1,652,673 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365091,590,583 - 1,678,680 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
METTL8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1577,477,231 - 77,525,714 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11577,477,229 - 77,564,492 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21586,863,793 - 86,948,404 (-)NCBISscrofa10.2Sscrofa10.2susScr3
METTL8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11056,851,898 - 56,951,920 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1056,852,279 - 56,950,983 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040142,594,431 - 142,738,373 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mettl8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247878,780,172 - 8,829,699 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247878,784,206 - 8,857,834 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Mettl8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1548,257,555 - 48,347,668 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mettl8
1590 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:88
Count of miRNA genes:73
Interacting mature miRNAs:76
Transcripts:ENSRNOT00000058524
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)351490129111359995Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)373592611110333156Rat
1358293Bw38Body weight QTL 3860.0000031body mass (VT:0001259)body weight (CMO:0000012)374364268119364268Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)35986366387321459Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)373592512136118980Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)35365182698651826Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)34887661993876619Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)34887661993876619Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)367641776167835660Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)358601291153936591Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)34790417292904172Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)349872657138829559Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)373592512136118980Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)35986366387321459Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35109256196092561Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)34865774493657744Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)370845569136091483Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)35986366383358329Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)358925062103925062Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)370311536115311536Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)34865774493657744Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)35076614595766145Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)35109256196092561Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)35076614595766145Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)34865774493657744Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)342158111124558371Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)37359251285062403Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893183708931Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)34865774493657744Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)33610140381101403Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)34865774493657744Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)342158111124558371Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)367641995130815812Rat

Markers in Region
RH134988  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2355,786,554 - 55,786,763 (+)MAPPERmRatBN7.2
Rnor_6.0357,570,128 - 57,570,337NCBIRnor6.0
Celera355,334,662 - 55,334,871UniSTS
Cytogenetic Map3q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 52 66 137 94 11 51 36 32 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000058524   ⟹   ENSRNOP00000055322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,177,904 - 76,266,687 (-)Ensembl
mRatBN7.2 Ensembl355,770,171 - 55,859,065 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075860   ⟹   ENSRNOP00000067958
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,177,904 - 76,271,363 (-)Ensembl
mRatBN7.2 Ensembl355,770,167 - 55,863,676 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076202   ⟹   ENSRNOP00000068431
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,181,551 - 76,271,363 (-)Ensembl
mRatBN7.2 Ensembl355,771,977 - 55,863,554 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000093222   ⟹   ENSRNOP00000076118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,163,732 - 76,271,363 (-)Ensembl
mRatBN7.2 Ensembl355,786,419 - 55,863,554 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000127583   ⟹   ENSRNOP00000111241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,167,476 - 76,271,400 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000134483   ⟹   ENSRNOP00000111422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,185,516 - 76,266,687 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000138988   ⟹   ENSRNOP00000105307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,177,904 - 76,266,469 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000139862   ⟹   ENSRNOP00000098991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,144,178 - 76,266,687 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000156985   ⟹   ENSRNOP00000105963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,177,904 - 76,265,849 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000161734   ⟹   ENSRNOP00000101575
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl376,177,904 - 76,271,363 (-)Ensembl
RefSeq Acc Id: NM_001399513   ⟹   NP_001386442
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,177,904 - 76,271,363 (-)NCBI
mRatBN7.2355,770,171 - 55,863,639 (-)NCBI
RefSeq Acc Id: NM_001399514   ⟹   NP_001386443
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,177,904 - 76,271,363 (-)NCBI
mRatBN7.2355,770,171 - 55,863,639 (-)NCBI
RefSeq Acc Id: XM_008761954   ⟹   XP_008760176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,177,900 - 76,267,300 (-)NCBI
mRatBN7.2355,770,167 - 55,860,682 (-)NCBI
Rnor_6.0357,257,394 - 57,642,096 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106364   ⟹   XP_038962292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,140,465 - 76,271,135 (-)NCBI
mRatBN7.2355,731,453 - 55,860,694 (-)NCBI
RefSeq Acc Id: XM_039106365   ⟹   XP_038962293
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,177,900 - 76,232,776 (-)NCBI
mRatBN7.2355,770,167 - 55,825,055 (-)NCBI
RefSeq Acc Id: XM_063284403   ⟹   XP_063140473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,140,465 - 76,271,367 (-)NCBI
RefSeq Acc Id: XM_063284404   ⟹   XP_063140474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,185,305 - 76,271,134 (-)NCBI
RefSeq Acc Id: XR_005502190
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,140,465 - 76,271,135 (-)NCBI
mRatBN7.2355,732,752 - 55,860,694 (-)NCBI
RefSeq Acc Id: XR_005502191
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8376,180,347 - 76,271,134 (-)NCBI
mRatBN7.2355,772,614 - 55,860,691 (-)NCBI
RefSeq Acc Id: XP_008760176   ⟸   XM_008761954
- Peptide Label: isoform X1
- UniProtKB: D3ZFN6 (UniProtKB/TrEMBL),   A6HM36 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038962292   ⟸   XM_039106364
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038962293   ⟸   XM_039106365
- Peptide Label: isoform X3
- UniProtKB: A6HM36 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076118   ⟸   ENSRNOT00000093222
Ensembl Acc Id: ENSRNOP00000068431   ⟸   ENSRNOT00000076202
Ensembl Acc Id: ENSRNOP00000055322   ⟸   ENSRNOT00000058524
Ensembl Acc Id: ENSRNOP00000067958   ⟸   ENSRNOT00000075860
RefSeq Acc Id: NP_001386443   ⟸   NM_001399514
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001386442   ⟸   NM_001399513
- Peptide Label: isoform 1
- UniProtKB: A6HM37 (UniProtKB/TrEMBL),   A6HM36 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063140473   ⟸   XM_063284403
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063140474   ⟸   XM_063284404
- Peptide Label: isoform X5
- UniProtKB: A0A096MK97 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105963   ⟸   ENSRNOT00000156985
Ensembl Acc Id: ENSRNOP00000105307   ⟸   ENSRNOT00000138988
Ensembl Acc Id: ENSRNOP00000101575   ⟸   ENSRNOT00000161734
Ensembl Acc Id: ENSRNOP00000111241   ⟸   ENSRNOT00000127583
Ensembl Acc Id: ENSRNOP00000098991   ⟸   ENSRNOT00000139862
Ensembl Acc Id: ENSRNOP00000111422   ⟸   ENSRNOT00000134483
Protein Domains
Methyltransferase type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZFN6-F1-model_v2 AlphaFold D3ZFN6 1-209 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561059 AgrOrtholog
BioCyc Gene G2FUF-49479 BioCyc
Ensembl Genes ENSRNOG00000009382 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058524 ENTREZGENE
  ENSRNOT00000058524.7 UniProtKB/TrEMBL
  ENSRNOT00000075860 ENTREZGENE
  ENSRNOT00000075860.3 UniProtKB/TrEMBL
  ENSRNOT00000076202.3 UniProtKB/TrEMBL
  ENSRNOT00000093222.3 UniProtKB/TrEMBL
  ENSRNOT00000127583.1 UniProtKB/TrEMBL
  ENSRNOT00000134483 ENTREZGENE
  ENSRNOT00000134483.1 UniProtKB/TrEMBL
  ENSRNOT00000138988 ENTREZGENE
  ENSRNOT00000138988.1 UniProtKB/TrEMBL
  ENSRNOT00000139862 ENTREZGENE
  ENSRNOT00000139862.1 UniProtKB/TrEMBL
  ENSRNOT00000156985.1 UniProtKB/TrEMBL
  ENSRNOT00000161734.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro Methyltransf_12 UniProtKB/TrEMBL
  MeTrfase UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene 502633 ENTREZGENE
PANTHER MRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL8 UniProtKB/TrEMBL
  PTHR22809 UniProtKB/TrEMBL
Pfam Methyltransf_12 UniProtKB/TrEMBL
PhenoGen Mettl8 PhenoGen
PIRSF Mettl2_prd UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009382 RatGTEx
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A096MJ18_RAT UniProtKB/TrEMBL
  A0A096MK97 ENTREZGENE, UniProtKB/TrEMBL
  A0A1W2Q633_RAT UniProtKB/TrEMBL
  A0ABK0L418_RAT UniProtKB/TrEMBL
  A0ABK0L5Y3_RAT UniProtKB/TrEMBL
  A0ABK0LKX9_RAT UniProtKB/TrEMBL
  A0ABK0LVR1_RAT UniProtKB/TrEMBL
  A0ABK0LYD1_RAT UniProtKB/TrEMBL
  A0ABK0M765_RAT UniProtKB/TrEMBL
  A6HM36 ENTREZGENE, UniProtKB/TrEMBL
  A6HM37 ENTREZGENE, UniProtKB/TrEMBL
  D3ZFN6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-09 Mettl8  methyltransferase 8, tRNA N3-cytidine  Mettl8  methyltransferase 8, methylcytidine  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-06-17 Mettl8  methyltransferase 8, methylcytidine  Mettl8  methyltransferase like 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2022-06-02 Mettl8  methyltransferase like 8  AABR07052486.1    Data merged from RGD:15003350 737654 PROVISIONAL
2019-11-08 AABR07052486.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-02-28 Mettl8  methyltransferase like 8  RGD1561059_predicted  similar to BC004636 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561059_predicted  similar to BC004636 protein (predicted)  LOC502633  similar to BC004636 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC502633  similar to BC004636 protein      Symbol and Name status set to provisional 70820 PROVISIONAL