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Gene: Bcas3 (BCAS3, microtubule associated cell migration factor) Rattus norvegicus

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Symbol:

Bcas3

Name:

BCAS3, microtubule associated cell migration factor

RGD ID:

1560788

Description:

Predicted to enable several functions, including beta-tubulin binding activity; enzyme activator activity; and histone acetyltransferase binding activity. Predicted to be involved in several processes, including cellular response to estrogen stimulus; positive regulation of endothelial cell migration; and positive regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including cytoskeleton; euchromatin; and phagophore assembly site. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Hengel-Maroofian-Schols syndrome. Orthologous to human BCAS3 (BCAS3 microtubule associated cell migration factor); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

BCAS3 microtubule associated cell migration factor; breast carcinoma amplified sequence 3; breast carcinoma-amplified sequence 3; LOC360587; LOC363662; RGD1560788; similar to Breast carcinoma amplified sequence 3 homolog (K20D4)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

Bcas3^em4Mcwi

Genetic Models:

SS-Bcas3^em4Mcwi

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	70,711,084 - 71,170,492 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	70,711,525 - 71,170,803 (+)	Ensembl				GRCr8
mRatBN7.2	10	70,213,710 - 70,673,080 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	70,214,098 - 70,673,080 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	74,834,096 - 75,293,055 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	74,338,875 - 74,797,845 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	69,803,543 - 70,262,482 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	72,756,548 - 73,271,851 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0	10	72,951,303 - 73,015,309 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	10	72,660,671 - 73,177,317 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	73,617,547 - 74,078,190 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	69,140,091 - 69,598,397 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast cancer (ISO)

Developmental Disabilities (ISO)

genetic disease (ISO)

Hengel-Maroofian-Schols syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

4-hydroxyphenyl retinamide (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

Bisphenol Z (ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

C60 fullerene (EXP)

caffeine (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

cisplatin (ISO)

clofibrate (ISO)

coumarin (ISO)

coumestrol (ISO)

dexamethasone (ISO)

doxorubicin (ISO)

fenthion (ISO)

fenvalerate (EXP)

FR900359 (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

lead diacetate (ISO)

lead(0) (ISO)

maneb (ISO)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

N-Nitrosopyrrolidine (ISO)

O-methyleugenol (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorooctanoic acid (ISO)

PhIP (ISO)

phytoestrogen (ISO)

propiconazole (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

serpentine asbestos (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sunitinib (ISO)

thimerosal (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

troglitazone (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA)

autophagy (IEA)

biological_process (ND)

cell-cell signaling (ISO)

cellular response to estrogen stimulus (IEA,ISO)

positive regulation of catalytic activity (ISO)

positive regulation of endothelial cell migration (ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of actin cytoskeleton organization (ISO)

response to estrogen (IEA,ISO)

response to starvation (IBA)

Cellular Component

cell leading edge (ISO)

cell periphery (ISO)

cytoplasm (IBA,IEA,ISO)

cytoplasmic microtubule (ISO)

cytoskeleton (IEA)

euchromatin (IEA,ISO)

intermediate filament cytoskeleton (ISO)

nucleus (IEA,ISO)

phagophore assembly site (IEA,ISO)

Molecular Function

acetyltransferase activator activity (IEA,ISO)

beta-tubulin binding (IEA,ISO)

chromatin binding (IEA,ISO)

GTPase activator activity (ISO)

histone acetyltransferase binding (IEA,ISO)

histone binding (IEA,ISO)

nuclear receptor binding (IEA,ISO)

phosphatidylinositol binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Breast cancer-amplified sequence 3, a target of metastasis-associated protein 1, contributes to tamoxifen resistance in premenopausal patients with breast cancer.	Gururaj AE, etal., Cell Cycle. 2006 Jul;5(13):1407-10. Epub 2006 Jul 1.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12477932	PMID:16099728	PMID:17505058	PMID:18030336	PMID:22300583

Genomics

Comparative Map Data

Bcas3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	70,711,084 - 71,170,492 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	70,711,525 - 71,170,803 (+)	Ensembl				GRCr8
mRatBN7.2	10	70,213,710 - 70,673,080 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	70,214,098 - 70,673,080 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	74,834,096 - 75,293,055 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	74,338,875 - 74,797,845 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	69,803,543 - 70,262,482 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	72,756,548 - 73,271,851 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0	10	72,951,303 - 73,015,309 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	10	72,660,671 - 73,177,317 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	73,617,547 - 74,078,190 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	69,140,091 - 69,598,397 (+)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

BCAS3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	60,677,851 - 61,392,831 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	60,677,453 - 61,392,838 (+)	Ensembl			hg38	GRCh38
GRCh37	17	58,755,212 - 59,470,192 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	56,109,954 - 56,824,981 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	17	56,110,014 - 56,824,973	NCBI
Celera	17	57,855,963 - 58,571,253 (+)	NCBI		Celera
Cytogenetic Map	17	q23.2	NCBI
HuRef	17	54,124,413 - 54,839,845 (+)	NCBI		HuRef
CHM1_1	17	58,819,940 - 59,534,717 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	61,546,666 - 62,261,697 (+)	NCBI		T2T-CHM13v2.0

Bcas3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	85,243,611 - 85,716,884 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	85,243,993 - 85,716,884 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	85,353,110 - 85,826,058 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	85,353,167 - 85,826,058 (+)	Ensembl			mm10	GRCm38
MGSCv37	11	85,166,666 - 85,639,560 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	85,169,409 - 85,642,246 (+)	NCBI		MGSCv36	mm8
Celera	11	94,976,839 - 95,452,393 (+)	NCBI		Celera
Cytogenetic Map	11	C	NCBI
cM Map	11	51.34	NCBI

Bcas3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	1,929,543 - 2,449,523 (+)	Ensembl
ChiLan1.0	NW_004955451	1,929,857 - 2,450,225 (+)	NCBI	ChiLan1.0	ChiLan1.0

BCAS3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	76,873,767 - 77,591,625 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	81,684,566 - 82,403,063 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	54,776,768 - 55,494,917 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	59,901,417 - 60,614,445 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	59,901,453 - 60,613,732 (+)	Ensembl			panPan2	panpan1.1

BCAS3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	35,253,617 - 35,845,206 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	35,253,917 - 35,843,328 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	34,482,988 - 35,073,854 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	36,064,944 - 36,656,494 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	36,064,946 - 36,656,084 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	34,845,828 - 35,437,477 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	35,131,472 - 35,722,494 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	35,219,300 - 35,811,204 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Bcas3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	34,313,061 - 34,885,621 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	2,189,583 - 2,761,331 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936490	2,189,693 - 2,761,989 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BCAS3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	36,894,401 - 37,475,151 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	12	36,894,727 - 37,475,221 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	38,345,061 - 39,039,973 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BCAS3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	31,912,523 - 32,620,308 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666077	2,660,424 - 3,371,778 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Bcas3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624871	2,444,952 - 3,034,311 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624871	2,444,262 - 3,036,148 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Bcas3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	84,918,303 - 85,369,437 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Bcas3
2791 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	77
Count of miRNA genes:	60
Interacting mature miRNAs:	72
Transcripts:	ENSRNOT00000004657
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	51071897	96071897	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31796281	76796281	Rat
631565	Hcuc4	Hepatic copper content QTL 4	4.15		liver copper amount (VT:0003065)	liver copper weight to liver dry weight ratio (CMO:0001512)	10	67439473	73950209	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	27023535	98502431	Rat
8657410	Bp374	Blood pressure QTL 374			heart left ventricle size trait (VT:0002753)	heart left ventricle end-diastolic diameter (CMO:0000982)	10	67476608	107713808	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	27443787	72443787	Rat
152025224	Bw193	Body weight QTL 193	6.47		body mass (VT:0001259)		10	52162433	75582749	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	35509383	91417879	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63719161	107713808	Rat
631557	Bp136	Blood pressure QTL 136		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	56868440	76129113	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42546145	107713808	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	58073360	103073360	Rat
12903252	Cm113	Cardiac mass QTL 113		0.047	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	66817119	107713808	Rat
70164	Bw21	Body weight QTL 21	4.36	0.00005	body mass (VT:0001259)	body weight (CMO:0000012)	10	54296336	99451733	Rat
61463	Bp12	Blood pressure QTL 12	6.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	41831278	86831278	Rat
1579919	Bp281	Blood pressure QTL 281		0.01	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50464802	95464802	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	64939013	107713808	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44939359	89939359	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45529164	96099749	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	54296227	107713808	Rat
12903269	Am15	Aortic mass QTL 15		0.042	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	66817119	107713808	Rat
10450493	Bp382	Blood pressure QTL 382		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50860288	95860288	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28950353	73950353	Rat
12903266	Cm114	Cardiac mass QTL 114		0.02	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	10	66817119	107713808	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	27443787	72443787	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14991535	86964295	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62556066	107556066	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	42823274	87823274	Rat
12880372	Am12	Aortic mass QTL 12		0.003	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	66817119	107713808	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62556066	107556066	Rat
12880375	Kidm66	Kidney mass QTL 66		0.009	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	66817119	107713808	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44939359	89939359	Rat
1357344	Bp249	Blood pressure QTL 249		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	67241334	98502431	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14991535	107556066	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	27443787	72443787	Rat
12880370	Cm105	Cardiac mass QTL 105		0.008	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	10	66817119	107713808	Rat
70198	BpQTLcluster9	Blood pressure QTL cluster 9	2.94		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	42823274	87823274	Rat
12880371	Cm106	Cardiac mass QTL 106		0.007	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	66817119	107713808	Rat
2306970	Anxrr22	Anxiety related response QTL 22	5.95		fear/anxiety-related behavior trait (VT:1000241)	number of periods of voluntary immobility (CMO:0001045)	10	61843496	98710773	Rat
11565453	Kidm58	Kidney mass QTL 58		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	10	66817119	107713808	Rat
7387312	Bw125	Body weight QTL 125	3	0.0047	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight (CMO:0000356)	10	65390777	107713808	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	67476608	73695498	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22931373	91127454	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6660923	73950353	Rat
2306792	Ean4	Experimental allergic neuritis QTL 4	4		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	49495492	94495492	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	52269185	107713808	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	67476608	73695498	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15533012	73695498	Rat
634329	Pia15	Pristane induced arthritis QTL 15	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	24662123	73695339	Rat
2298481	Eau9	Experimental allergic uveoretinitis QTL 9		0.0169	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	64139597	83061459	Rat
2298480	Eau7	Experimental allergic uveoretinitis QTL 7		0.0049	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	35509383	80509383	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68920187	107713808	Rat
1358915	Stresp7	Stress response QTL 7	3.52		blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	65307813	107713808	Rat
70363	Bp71	Blood pressure QTL 71		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	61843496	106843496	Rat
61402	Niddm3	Non-insulin dependent diabetes mellitus QTL 3	4.58		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	61843633	83061236	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29800910	91417879	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70698731	107713808	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	27587226	96099902	Rat
2289985	Bp305	Blood pressure QTL 305			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	29076978	74076978	Rat
1354608	Cm33	Cardiac mass QTL 33	2.8		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	10	55307972	93608131	Rat
1558643	Cm44	Cardiac mass QTL 44	4.8	0.0000368	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	61843496	100198886	Rat
8552805	Bw145	Body weight QTL 145	2.2		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	10	43608793	88608793	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23948641	107713808	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	27443787	72443787	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40535708	107713808	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40535708	107713808	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14991535	107713808	Rat
7207811	Bmd90	Bone mineral density QTL 90	5.2		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	10	49943710	94943710	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31129113	76129113	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40535708	107713808	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44939359	89939359	Rat
1581559	Eae18	Experimental allergic encephalomyelitis QTL 18		0.00002	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	10	66108888	107555881	Rat
6893336	Cm75	Cardiac mass QTL 75	0.1	0.87	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	61843496	100198886	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47869129	92869129	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6864618	96620484	Rat
12880050	Am10	Aortic mass QTL 10		0.016	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	10	39503487	84503487	Rat
2292436	Bp310	Blood pressure QTL 310			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	50604677	95604677	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	35509383	88177745	Rat
634354	Rends3	Renal damage susceptibility QTL 3		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	10	61997479	106997479	Rat
2301405	Cm69	Cardiac mass QTL 69		0.031	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	10	66817119	107713808	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	27023535	99451848	Rat

Markers in Region

D10Got89

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	70,325,559 - 70,325,682 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	72,766,459 - 72,766,581	NCBI	Rnor6.0
Rnor_5.0	10	72,670,514 - 72,670,636	UniSTS	Rnor5.0
RGSC_v3.4	10	73,728,933 - 73,729,055	RGD	RGSC3.4
RGSC_v3.4	10	73,728,934 - 73,729,056	UniSTS	RGSC3.4
Celera	10	69,251,939 - 69,252,061	UniSTS
RGSC_v3.1	10	73,743,303 - 73,743,425	RGD
RH 2.0 Map	10	715.4	RGD
Cytogenetic Map	10	q26	UniSTS

D10Chm138

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	70,193,411 - 70,193,658 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	72,930,356 - 72,930,606	NCBI	Rnor6.0
Rnor_5.0	10	72,834,326 - 72,834,576	UniSTS	Rnor5.0
RGSC_v3.4	10	73,596,411 - 73,596,657	UniSTS	RGSC3.4
Celera	10	69,119,463 - 69,119,676	UniSTS
Cytogenetic Map	10	q26	UniSTS

D10Chm139

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	70,253,424 - 70,253,671 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	72,989,913 - 72,990,157	NCBI	Rnor6.0
Rnor_5.0	10	72,893,869 - 72,894,113	UniSTS	Rnor5.0
RGSC_v3.4	10	73,656,922 - 73,657,166	UniSTS	RGSC3.4
Celera	10	69,179,404 - 69,179,568	UniSTS
Cytogenetic Map	10	q26	UniSTS

RH132054

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	70,672,814 - 70,673,009 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	73,271,586 - 73,271,780	NCBI	Rnor6.0
Rnor_5.0	10	73,177,052 - 73,177,246	UniSTS	Rnor5.0
RGSC_v3.4	10	74,077,925 - 74,078,119	UniSTS	RGSC3.4
Celera	10	69,598,132 - 69,598,326	UniSTS
Cytogenetic Map	10	q26	UniSTS

BF398745

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	70,666,593 - 70,666,839 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	73,265,365 - 73,265,610	NCBI	Rnor6.0
Rnor_5.0	10	73,170,831 - 73,171,076	UniSTS	Rnor5.0
RGSC_v3.4	10	74,071,704 - 74,071,949	UniSTS	RGSC3.4
Celera	10	69,591,909 - 69,592,154	UniSTS
Cytogenetic Map	10	q26	UniSTS

RH134882

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	70,524,251 - 70,524,447 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	73,123,786 - 73,123,981	NCBI	Rnor6.0
Rnor_5.0	10	73,029,249 - 73,029,444	UniSTS	Rnor5.0
RGSC_v3.4	10	73,929,375 - 73,929,570	UniSTS	RGSC3.4
Celera	10	69,450,128 - 69,450,323	UniSTS
Cytogenetic Map	10	q26	UniSTS

RH134984

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	70,656,518 - 70,656,713 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	73,255,290 - 73,255,484	NCBI	Rnor6.0
Rnor_5.0	10	73,160,756 - 73,160,950	UniSTS	Rnor5.0
RGSC_v3.4	10	74,061,629 - 74,061,823	UniSTS	RGSC3.4
Celera	10	69,581,824 - 69,582,018	UniSTS
Cytogenetic Map	10	q26	UniSTS

RH136813

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	70,207,552 - 70,207,760 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	72,944,830 - 72,945,037	NCBI	Rnor6.0
Rnor_5.0	10	72,848,800 - 72,849,007	UniSTS	Rnor5.0
RGSC_v3.4	10	73,611,010 - 73,611,217	UniSTS	RGSC3.4
Celera	10	69,133,542 - 69,133,749	UniSTS
Cytogenetic Map	10	q26	UniSTS

Genetic Models

This gene Bcas3 is modified in the following models/strains:

SS-Bcas3^em4Mcwi

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	hemolymphoid system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	sensory system	visual system
14	2	36	101	133	275	189	22	99	72	64	34	34

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001173430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086494	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086496	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039086500	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269536	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063269537	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010055214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010055215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC158637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000095630 ⟹ ENSRNOP00000094777

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	70,711,541 - 71,168,056 (+)	Ensembl
mRatBN7.2 Ensembl	10	70,214,098 - 70,670,694 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096172 ⟹ ENSRNOP00000092518

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	70,711,541 - 71,170,575 (+)	Ensembl
mRatBN7.2 Ensembl	10	70,214,098 - 70,673,080 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098788 ⟹ ENSRNOP00000097649

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	70,711,525 - 71,170,667 (+)	Ensembl
mRatBN7.2 Ensembl	10	70,214,098 - 70,673,080 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099126 ⟹ ENSRNOP00000087925

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	70,711,525 - 71,170,803 (+)	Ensembl
mRatBN7.2 Ensembl	10	70,214,098 - 70,673,080 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104458 ⟹ ENSRNOP00000082383

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	70,711,525 - 71,170,667 (+)	Ensembl
mRatBN7.2 Ensembl	10	70,214,098 - 70,673,080 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000110774 ⟹ ENSRNOP00000084198

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	70,711,525 - 70,870,555 (+)	Ensembl
mRatBN7.2 Ensembl	10	70,214,098 - 70,373,150 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119090 ⟹ ENSRNOP00000096642

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	10	70,711,541 - 71,170,803 (+)	Ensembl
mRatBN7.2 Ensembl	10	70,214,098 - 70,673,066 (+)	Ensembl

RefSeq Acc Id:

NM_001173430 ⟹ NP_001166901

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,525 - 71,170,492 (+)	NCBI
mRatBN7.2	10	70,214,102 - 70,673,080 (+)	NCBI
Rnor_6.0	10	72,756,548 - 73,271,851 (+)	NCBI
Rnor_5.0	10	72,660,671 - 73,177,317 (+)	NCBI
Celera	10	69,140,091 - 69,598,397 (+)	NCBI

Sequence:

show sequence

CTGGAGCTGGAGAACAGCGTTTACCGGCGGAGCGGCCGTTTTAAATTATAGGAAGAAAGATTCA
GCAAAAGAGTGAACTGTTCTCACTTTCAGATGTTAGGCAGTTCAAGGCCAGCCTCAATTACAGG
GTCTTATGAATGAAACCATGGCTACAGATTCTCCTAGAAGACCCAGTCGCTGCACTGGTGGAGT
TGTGGTCCGCCCTCAGGCCGTCACGGAGCAGTCCTACATGGAAAGCGTTGTGACTTTTCTGCAG
GATGTCGTGCCACAGGCTTACAGTGGGACACCCCTAACGGAAGAAAAGGAGAAGATAGTTTGGG
TCCGGTTTGAGAATGCAGATCTGAATGATACATCACGGAATCTAGAATTTCATGAACTGCATAG
CACGGGAAATGAGCCTCCTCTGCTGGTTATGATCGGCTACAGTGACGGAATGCAGGTGTGGGGC
ATCCCTATCAGCGGGGAAGCCCAGGAGCTCTTCTCTGTTCGACATGGTCCAGTCCGAGCAGCTA
GAATCTTGCCTGCTCCACAGTTGGGTGCTCAAAAGTGTGATAACTTTGCTGAGAAAAGACCTCT
TCTTGGTGTTTGTAAGAGCATTGGATCTTCAGGCACGACGCCACCATACTGCTGTGTGGATCTG
TACTCACTTCGTACGGGGGAGATGGTCAAGTCCATTCAGTTTAAAACGCCCATTTATGATCTTC
ATTGTAATAAGCGGATCCTCGTCGTAGTCCTGCAGGAGAAAATCGCTGCCTTCGACAGCTGTAC
TTTCACAAAAAAATTTTTTGTCACAAGTTGTTATCCTTGTCCTGGGCCAAACATGAATCCTATT
GCTCTTGGGAGCCGTTGGCTTGCTTATGCAGAAAATAAGCTGATTCGCTGTCACCAGTCCCGTG
GCGGAGCCTGTGGAGACAACATTCAGTCTTACACTGCCACTGTCATTAGTGCTGCTAAAACACT
GAAAAGTGGCCTGACGATGGTTGGGAAAGTGGTGACTCAACTGACAGGCACACTGCCCTCAGGA
GTGACAGATGATGACATAGCCATACACTGCAACTCAAGACGGAGCCCCTTGGTGCCGGGCATCA
TCACAGTCATAGACACTGAGACAGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATTCAGACAG
TGATGGCATTGTGGCCCACTTCCCTGCCCACGAGAAGCCAGTGTGCTGTATGGCTTTTAATACA
AGTGGAATGCTTTTAGTCACAACAGATACTCTTGGCCATGACTTTCATGTCTTCCAAATCCTGA
CTCATCCTTGGTCATCCTCACAGTGTGCTGTCCATCACCTGTATACACTTCACAGGGGAGAGAC
CGAGGCCAAAGTTCAGGACATCTGTTTCAGCCATGATTGTCGTTGGGTGGTGGTCAGTACCCTC
CGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAGCCTTGTGTCCGCACACACA
TGTCACCGCGAGTAGTGAATCGCATGAGCCGTTTCCAGAAAAGTGCTGGGCTGGAAGAGATTGA
ACAAGAGCTGACATCTAAGCAAGGCGGCCGCTGTAGTCCTGTCCCAGGCCTGTCCAGCAGCCCT
TCCGGCTCCCCGCTGCATGGGAAGCTGAGTAGCCAAGACTCTTACAATAACTTTACCAACAACA
ACCCTGGCAACCCCCGGCTTTCTCCCCTCCCCAGCTTGATGGTAGTGACACCTCTTGCACAAAT
CAAGCAGCCAATGACATTGGGGACCATCACGAAACGAACAGGGCCTTATCTCTTTGGAGCGGGG
TGTTTTTCCATAAAAGCTCCATGCAAAGTTAAACCGCCTCCACAAATTTCTCCAAGCAAATCGA
TGGGCGGGGAGTTTTGCGTGGCCGCAGTGTTTGGGACCTCCAGGTCGTGGTTTGCAAACAATGC
TGGTCTGAAACGGGAAAAAGATCAGTCCAAACAAGTTGTGGTTGAATCTCTTTATATCATCAGT
TGCTACGGGACCTTAGTGGAGCACATGATTGAGCCTCGGCCTATCAGTACTGCTCCCAAGATAA
GTGACGACACACCACTGGAGATAATGACCTCACCTCGTGCCAGCTGGACACTTGTCAGAACGCC
TCAGTGGAACGAACTGCAGCCACCATTCAATGCGAATCACCCCCTGCTCCTTGCGGCAGAAGCA
GTGCAGTATTACCAGCTCCTGCTGGCCGGCTCACTTCCCCCTGGAAGTCCTGGCCCCATTACTC
GACATGGGTCCTATGACAGTTTAGCATCTGACCACAGCGGACAGGAAGATGAAGAATGGCTATC
CCAGGTTGAAATTGTGACACACACTGGACCCCACAGGCGCCTATGGATGGGTCCACAGTTCCAG
TTCAAAACCATCCACCCCTCAGGCCAGACCACGGTCATATCATCTAGTTCTTCTGTGTTACAGT
CTCATGGACCTAGTGACACACCACAGCCGCTCTTGGACTTTGATACAGATGATCTAGATCTTAA
CAGCCTCAGGATCCAGCCGGTCCGCTCTGACCCAGTCAGCATGCCAGGGTCATCCCGTCCAGTC
TCTGATCGAAGGGGAGTTTCCACCGTGATCGATGCTGCCTCAGGTACCTTCGACCGGAGCGTGA
CCCTGTTGGAGGTGTGTGGGAGCTGGCCTGAGGGCTTCGGGCTGCGACATATGTCCTCCATGGA
GCACACAGAAGAGGGCCTCCGGGAACGGCTTGCAGATGCCATGGCCGAGTCACCGAGCCGAGAC
GTTGTGGGATCTGGAACAGAACTTCAGCGAGAGGGAAGCATCGAGACTCTGAGTAACAGCTCAG
GCTCCACCAGTGGCAGCATCCCAAGAAACTTTGATGGCTACCGATCTCCGCTCCCGACCAACGA
GAGCCAGCCGCTCAGCCTCTTCCCCACTGGCTTCCCATAGACACCAGCCACCTGCTTCTGACTG
GCTGGCCTGCTCACCCCCTAGAGGGACTGACAGGGGTGGAGAGAAATGCCCCTATCTCCCTACA
CCCCCACCCCCATAAACCTCTGGTCCCACCCTTTTCAGTCTCCTCAACCCCACCTTCCCGGAGC
TTAGTGACAGCAGCCGCTCATCCCTAACTGGACTGAAGACACCTTCGGAACACCTCAGTACACC
CTGACTTCTCCCACTCCTGTCAGTGGGGGCTGTGGCCTGAAGAGACTGCAGAACTCAGTCCCTT
CTCTCTTTGCACATAATGTCCTGCATTGGATCCGCTTTTGTATTTTCTAACTACCCACAGGGGA
CTGGAACAGTGGCCAGATCTTAGGGCCTTGGGTAGGGAAGAGTTGAAAGGTCCAGCCAGGCATT
TTGGTGGACATCAGCCCTAGCCCAGTTGAGGCTGTGATGCACACTGCCCCCAGGTATCAGTTCT
TTCTAAAAAAGGGGTTAACTGAGGCCTAGAGTGATAGGGAAAAAGGAAAGACCTCCCCTTGCCC
CTGCTTCCCTGTTGGCTCATGGGGAGATTTGTCTGTCTTATCTTTAAACCCTTGTACCCTGGTC
CTGTGCTGTTCAGTGAAGGAAACTGAAGTTACTGAGGCCGTGTCAGAAGTGCACGTCTTGTCCA
ATAAATCTTGCTGCAATTGGTGTTCA

hide sequence

RefSeq Acc Id:

XM_039086494 ⟹ XP_038942422

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,146 - 71,170,492 (+)	NCBI
mRatBN7.2	10	70,213,714 - 70,673,080 (+)	NCBI

RefSeq Acc Id:

XM_039086495 ⟹ XP_038942423

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,144 - 71,170,492 (+)	NCBI
mRatBN7.2	10	70,213,713 - 70,673,080 (+)	NCBI

RefSeq Acc Id:

XM_039086496 ⟹ XP_038942424

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,148 - 71,170,492 (+)	NCBI
mRatBN7.2	10	70,213,716 - 70,673,080 (+)	NCBI

RefSeq Acc Id:

XM_039086497 ⟹ XP_038942425

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,147 - 71,170,492 (+)	NCBI
mRatBN7.2	10	70,213,716 - 70,673,080 (+)	NCBI

RefSeq Acc Id:

XM_039086498 ⟹ XP_038942426

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,148 - 71,170,492 (+)	NCBI
mRatBN7.2	10	70,213,717 - 70,673,080 (+)	NCBI

RefSeq Acc Id:

XM_039086499 ⟹ XP_038942427

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,084 - 71,170,492 (+)	NCBI
mRatBN7.2	10	70,213,713 - 70,673,080 (+)	NCBI

RefSeq Acc Id:

XM_039086500 ⟹ XP_038942428

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,328 - 71,170,492 (+)	NCBI
mRatBN7.2	10	70,213,720 - 70,673,080 (+)	NCBI

RefSeq Acc Id:

XM_063269533 ⟹ XP_063125603

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,712,920 - 71,170,492 (+)	NCBI

RefSeq Acc Id:

XM_063269534 ⟹ XP_063125604

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,142 - 71,170,492 (+)	NCBI

RefSeq Acc Id:

XM_063269535 ⟹ XP_063125605

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,712,932 - 71,170,492 (+)	NCBI

RefSeq Acc Id:

XM_063269536 ⟹ XP_063125606

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,712,967 - 71,170,492 (+)	NCBI

RefSeq Acc Id:

XM_063269537 ⟹ XP_063125607

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,147 - 71,170,492 (+)	NCBI

RefSeq Acc Id:

XR_010055214

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,142 - 71,147,322 (+)	NCBI

RefSeq Acc Id:

XR_010055215

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	70,711,145 - 71,147,322 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001166901	(Get FASTA)	NCBI Sequence Viewer
	XP_038942422	(Get FASTA)	NCBI Sequence Viewer
	XP_038942423	(Get FASTA)	NCBI Sequence Viewer
	XP_038942424	(Get FASTA)	NCBI Sequence Viewer
	XP_038942425	(Get FASTA)	NCBI Sequence Viewer
	XP_038942426	(Get FASTA)	NCBI Sequence Viewer
	XP_038942427	(Get FASTA)	NCBI Sequence Viewer
	XP_038942428	(Get FASTA)	NCBI Sequence Viewer
	XP_063125603	(Get FASTA)	NCBI Sequence Viewer
	XP_063125604	(Get FASTA)	NCBI Sequence Viewer
	XP_063125605	(Get FASTA)	NCBI Sequence Viewer
	XP_063125606	(Get FASTA)	NCBI Sequence Viewer
	XP_063125607	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI58638	(Get FASTA)	NCBI Sequence Viewer
	EDM05545	(Get FASTA)	NCBI Sequence Viewer
	EDM05546	(Get FASTA)	NCBI Sequence Viewer
	EDM05547	(Get FASTA)	NCBI Sequence Viewer
	EDM05548	(Get FASTA)	NCBI Sequence Viewer
	EDM05549	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000082383
	ENSRNOP00000082383.1
	ENSRNOP00000084198.1
	ENSRNOP00000087925
	ENSRNOP00000087925.1
	ENSRNOP00000092518
	ENSRNOP00000092518.1
	ENSRNOP00000094777
	ENSRNOP00000094777.1
	ENSRNOP00000096642
	ENSRNOP00000096642.1
	ENSRNOP00000097649
	ENSRNOP00000097649.1

RefSeq Acc Id:

NP_001166901 ⟸ NM_001173430

- UniProtKB:

A0A8I6A420 (UniProtKB/TrEMBL), A6HHP1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MNETMATDSPRRPSRCTGGVVVRPQAVTEQSYMESVVTFLQDVVPQAYSGTPLTEEKEKIVWVR
FENADLNDTSRNLEFHELHSTGNEPPLLVMIGYSDGMQVWGIPISGEAQELFSVRHGPVRAARI
LPAPQLGAQKCDNFAEKRPLLGVCKSIGSSGTTPPYCCVDLYSLRTGEMVKSIQFKTPIYDLHC
NKRILVVVLQEKIAAFDSCTFTKKFFVTSCYPCPGPNMNPIALGSRWLAYAENKLIRCHQSRGG
ACGDNIQSYTATVISAAKTLKSGLTMVGKVVTQLTGTLPSGVTDDDIAIHCNSRRSPLVPGIIT
VIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTH
PWSSSQCAVHHLYTLHRGETEAKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQPCVRTHMS
PRVVNRMSRFQKSAGLEEIEQELTSKQGGRCSPVPGLSSSPSGSPLHGKLSSQDSYNNFTNNNP
GNPRLSPLPSLMVVTPLAQIKQPMTLGTITKRTGPYLFGAGCFSIKAPCKVKPPPQISPSKSMG
GEFCVAAVFGTSRSWFANNAGLKREKDQSKQVVVESLYIISCYGTLVEHMIEPRPISTAPKISD
DTPLEIMTSPRASWTLVRTPQWNELQPPFNANHPLLLAAEAVQYYQLLLAGSLPPGSPGPITRH
GSYDSLASDHSGQEDEEWLSQVEIVTHTGPHRRLWMGPQFQFKTIHPSGQTTVISSSSSVLQSH
GPSDTPQPLLDFDTDDLDLNSLRIQPVRSDPVSMPGSSRPVSDRRGVSTVIDAASGTFDRSVTL
LEVCGSWPEGFGLRHMSSMEHTEEGLRERLADAMAESPSRDVVGSGTELQREGSIETLSNSSGS
TSGSIPRNFDGYRSPLPTNESQPLSLFPTGFP

hide sequence

RefSeq Acc Id:	XP_038942423 ⟸ XM_039086495
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6G9E5 (UniProtKB/TrEMBL), A0A8I6ASA0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038942427 ⟸ XM_039086499
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I6AT23 (UniProtKB/TrEMBL), A0A8I6ASA0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038942422 ⟸ XM_039086494
- Peptide Label:	isoform X2
- UniProtKB:	A6HHP1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038942425 ⟸ XM_039086497
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6ASA0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038942424 ⟸ XM_039086496
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6APN6 (UniProtKB/TrEMBL), A0A8I6ASA0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038942426 ⟸ XM_039086498
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6A420 (UniProtKB/TrEMBL), A6HHP1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038942428 ⟸ XM_039086500
- Peptide Label:	isoform X8
- UniProtKB:	A0A8I6ASA0 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000096642 ⟸ ENSRNOT00000119090

Ensembl Acc Id:

ENSRNOP00000092518 ⟸ ENSRNOT00000096172

Ensembl Acc Id:

ENSRNOP00000084198 ⟸ ENSRNOT00000110774

Ensembl Acc Id:

ENSRNOP00000097649 ⟸ ENSRNOT00000098788

Ensembl Acc Id:

ENSRNOP00000094777 ⟸ ENSRNOT00000095630

Ensembl Acc Id:

ENSRNOP00000087925 ⟸ ENSRNOT00000099126

Ensembl Acc Id:

ENSRNOP00000082383 ⟸ ENSRNOT00000104458

RefSeq Acc Id:	XP_063125604 ⟸ XM_063269534
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GK77 (UniProtKB/TrEMBL), A0A8I6ASA0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125607 ⟸ XM_063269537
- Peptide Label:	isoform X9
- UniProtKB:	A0A8I6ASA0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125603 ⟸ XM_063269533
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6GK77 (UniProtKB/TrEMBL), A0A8I6ASA0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125605 ⟸ XM_063269535
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I6A420 (UniProtKB/TrEMBL), A6HHP1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063125606 ⟸ XM_063269536
- Peptide Label:	isoform X8
- UniProtKB:	A0A8I6ASA0 (UniProtKB/TrEMBL)

Protein Domains

BCAS3 BCAS3 WD40

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1560788	AgrOrtholog
BioCyc Gene	G2FUF-23820	BioCyc
Ensembl Genes	ENSRNOG00000066893	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000095630	ENTREZGENE
	ENSRNOT00000095630.2	UniProtKB/TrEMBL
	ENSRNOT00000096172	ENTREZGENE
	ENSRNOT00000096172.2	UniProtKB/TrEMBL
	ENSRNOT00000098788	ENTREZGENE
	ENSRNOT00000098788.2	UniProtKB/TrEMBL
	ENSRNOT00000099126	ENTREZGENE
	ENSRNOT00000099126.2	UniProtKB/TrEMBL
	ENSRNOT00000104458	ENTREZGENE
	ENSRNOT00000104458.2	UniProtKB/TrEMBL
	ENSRNOT00000110774.2	UniProtKB/TrEMBL
	ENSRNOT00000119090	ENTREZGENE
	ENSRNOT00000119090.2	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7456859	IMAGE-MGC_LOAD
InterPro	BCAS3	UniProtKB/TrEMBL
	BCAS3-like	UniProtKB/TrEMBL
	BCAS3_WD40	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:363662	UniProtKB/TrEMBL
MGC_CLONE	MGC:187553	IMAGE-MGC_LOAD
NCBI Gene	363662	ENTREZGENE
PANTHER	BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR	UniProtKB/TrEMBL
	PTHR13268	UniProtKB/TrEMBL
Pfam	BCAS3	UniProtKB/TrEMBL
	BCAS3_WD40	UniProtKB/TrEMBL
PhenoGen	Bcas3	PhenoGen
RatGTEx	ENSRNOG00000066893	RatGTEx
Superfamily-SCOP	SSF50978	UniProtKB/TrEMBL
UniProt	A0A8I6A420	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6APN6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ASA0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AT23	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6G9E5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GA12_RAT	UniProtKB/TrEMBL
	A0A8I6GK77	ENTREZGENE, UniProtKB/TrEMBL
	A6HHP1	ENTREZGENE, UniProtKB/TrEMBL
	B0BN06_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-06-15	Bcas3	breast carcinoma amplified sequence 3	Bcas3_predicted	breast carcinoma amplified sequence 3 (predicted)	Data merged from RGD:1309481	1643240	APPROVED
2008-02-28	Bcas3	breast carcinoma amplified sequence 3	RGD1560788_predicted	similar to Breast carcinoma amplified sequence 3 homolog (K20D4) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1560788_predicted	similar to Breast carcinoma amplified sequence 3 homolog (K20D4) (predicted)	LOC363662	similar to Breast carcinoma amplified sequence 3 homolog (K20D4)	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC363662	similar to Breast carcinoma amplified sequence 3 homolog (K20D4)			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-01-12	Bcas3_predicted	breast carcinoma amplified sequence 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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