Advanced Search (OLGA)

Gene: Zkscan1 (zinc finger with KRAB and SCAN domains 1) Rattus norvegicus

Analyze

Symbol:

Zkscan1

Name:

zinc finger with KRAB and SCAN domains 1

RGD ID:

1560616

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZKSCAN1 (zinc finger with KRAB and SCAN domains 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

MGC116363; zinc finger protein 36 (KOX 18); zinc finger protein with KRAB and SCAN domains 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	22,080,319 - 22,101,389 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	22,080,324 - 22,101,387 (+)	Ensembl				GRCr8
mRatBN7.2	12	16,966,287 - 16,987,680 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	16,966,654 - 16,983,865 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	17,789,870 - 17,806,147 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	18,413,615 - 18,429,892 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	17,467,019 - 17,483,296 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	19,231,092 - 19,247,393 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	19,231,092 - 19,247,387 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	21,289,534 - 21,310,622 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	17,530,383 - 17,546,785 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	18,897,020 - 18,913,306 (+)	NCBI		Celera
Cytogenetic Map	12	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (ISO)

casticin (ISO)

chlorpyrifos (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

coumestrol (ISO)

crotonaldehyde (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

dioxygen (EXP)

dorsomorphin (ISO)

elemental selenium (ISO)

Enterolactone (ISO)

epoxiconazole (ISO)

folic acid (ISO)

FR900359 (ISO)

furan (EXP)

gallic acid (ISO)

nickel atom (ISO)

okadaic acid (ISO)

p-toluidine (EXP)

paracetamol (EXP)

paraquat (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

thiram (ISO)

tributylstannane (EXP)

trichostatin A (ISO)

triphenyl phosphate (EXP,ISO)

troglitazone (ISO)

valproic acid (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA-templated transcription (IEA)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

identical protein binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific double-stranded DNA binding (IEA)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334

Genomics

Comparative Map Data

Zkscan1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	22,080,319 - 22,101,389 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	12	22,080,324 - 22,101,387 (+)	Ensembl				GRCr8
mRatBN7.2	12	16,966,287 - 16,987,680 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	16,966,654 - 16,983,865 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	12	17,789,870 - 17,806,147 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	18,413,615 - 18,429,892 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	17,467,019 - 17,483,296 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	19,231,092 - 19,247,393 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	19,231,092 - 19,247,387 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	12	21,289,534 - 21,310,622 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	12	17,530,383 - 17,546,785 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	12	18,897,020 - 18,913,306 (+)	NCBI		Celera
Cytogenetic Map	12	q11	NCBI

ZKSCAN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	100,015,596 - 100,045,374 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	100,015,570 - 100,041,689 (+)	Ensembl			hg38	GRCh38
GRCh37	7	99,613,219 - 99,642,997 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	99,451,155 - 99,473,339 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	7	99,257,869 - 99,280,054	NCBI
Celera	7	94,347,766 - 94,369,948 (+)	NCBI		Celera
Cytogenetic Map	7	q22.1	NCBI
HuRef	7	94,248,895 - 94,270,995 (+)	NCBI		HuRef
CHM1_1	7	99,543,395 - 99,565,575 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	101,255,101 - 101,284,872 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	98,973,342 - 98,995,525 (+)	NCBI

Zkscan1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	138,083,312 - 138,106,084 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	138,083,346 - 138,106,084 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	138,085,050 - 138,107,822 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	138,085,084 - 138,107,822 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	138,526,312 - 138,549,050 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	138,314,872 - 138,337,610 (+)	NCBI		MGSCv36	mm8
Celera	5	135,064,847 - 135,087,824 (+)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	76.95	NCBI

Zkscan1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955573	830,342 - 836,216 (-)	Ensembl
ChiLan1.0 Ensembl	NW_004955573	854,380 - 869,870 (-)	Ensembl
ChiLan1.0	NW_004955573	830,897 - 869,857 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZKSCAN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	117,934,934 - 117,969,044 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	166,199,568 - 166,233,676 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	92,050,741 - 92,080,554 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	105,484,170 - 105,514,778 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	105,484,185 - 105,502,895 (+)	Ensembl			panPan2	panpan1.1

Zkscan1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	133,844,331 - 133,885,668 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936543	180,662 - 192,238 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0 Ensembl	NW_004936543	150,850 - 165,282 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936543	150,845 - 192,197 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZKSCAN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	7,920,675 - 7,942,498 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	3	7,920,640 - 7,959,462 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	7,175,404 - 7,194,287 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Zkscan1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	16	15,462,373 - 15,483,392 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Zkscan1
198 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	540
Count of miRNA genes:	270
Interacting mature miRNAs:	330
Transcripts:	ENSRNOT00000045379
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	5921918	25247790	Rat
61443	Btemp2	Thermal response to stress QTL 2	3.3	0.000094	body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	12	20139028	26430640	Rat
70213	Niddm27	Non-insulin dependent diabetes mellitus QTL 27	3.72		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	11200494	52308831	Rat
2306789	Ean6	Experimental allergic neuritis QTL 6	4.9		nervous system integrity trait (VT:0010566)	experimental autoimmune neuritis severity score (CMO:0001528)	12	1	29775522	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	3489416	48489416	Rat
1331739	Hrtrt14	Heart rate QTL 14	3.56232		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	12	1	38687564	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	18473041	52308831	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200497	52308831	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	15264248	52308831	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	1	33700600	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	11743528	52308831	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	11200494	52308831	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	1	38635130	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28133365	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	12233000	30490641	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	17464979	46784661	Rat
1300174	Bw15	Body weight QTL 15	2.93		body mass (VT:0001259)	body weight loss (CMO:0001399)	12	1	28606299	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	16187438	52308831	Rat
1331787	Rf41	Renal function QTL 41	2.998		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	12	1	33700556	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	16135029	52308831	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	51213550	Rat
1331763	Wbc2	White blood cell count QTL 2	3.162		leukocyte quantity (VT:0000217)	total white blood cell count (CMO:0000365)	12	11200494	52308831	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	18749469	36488809	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	1	24849755	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	11200494	52308831	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	41361854	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	18749469	34312613	Rat
1298081	Cia25	Collagen induced arthritis QTL 25	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	2747694	47747694	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	18473041	52308831	Rat
2303568	Bw88	Body weight QTL 88	3		body mass (VT:0001259)	body weight (CMO:0000012)	12	1	28606299	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	3087180	48087180	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
7243862	Mcs30	Mammary carcinoma susceptibility QTL 30	8.62		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	12	5633306	50633306	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	16135029	52308831	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	7901625	33938215	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	11200494	52308831	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	16187438	33700556	Rat

Markers in Region

C87323

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	16,982,371 - 16,982,529 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	19,246,813 - 19,246,970	NCBI	Rnor6.0
Rnor_5.0	12	21,305,314 - 21,305,471	UniSTS	Rnor5.0
RGSC_v3.4	12	17,546,205 - 17,546,362	UniSTS	RGSC3.4
Celera	12	18,912,726 - 18,912,883	UniSTS
Cytogenetic Map	12	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
22	12	75	184	91	90	59	121	59	6	423	231	13	166	103	117	31	26	26

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001025760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089696	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089697	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491663	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005491664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC099191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000045379 ⟹ ENSRNOP00000051042

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	22,080,350 - 22,101,387 (+)	Ensembl
mRatBN7.2 Ensembl	12	16,966,654 - 16,982,946 (+)	Ensembl
Rnor_6.0 Ensembl	12	19,231,092 - 19,247,387 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099099 ⟹ ENSRNOP00000081334

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	12	22,080,324 - 22,101,387 (+)	Ensembl
mRatBN7.2 Ensembl	12	16,966,654 - 16,983,865 (+)	Ensembl

RefSeq Acc Id:

NM_001025760 ⟹ NP_001020931

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	22,080,365 - 22,096,661 (+)	NCBI
mRatBN7.2	12	16,966,654 - 16,982,952 (+)	NCBI
Rnor_6.0	12	19,231,092 - 19,247,393 (+)	NCBI
Rnor_5.0	12	21,289,534 - 21,310,622 (+)	NCBI
RGSC_v3.4	12	17,530,383 - 17,546,785 (+)	RGD
Celera	12	18,897,020 - 18,913,306 (+)	RGD

Sequence:

show sequence

CGAGGTGTTGGGAGGGCCTAGGTCGGTGTGCAGTGCCCTTCGGCCGGGTTGAACCTGGGAGTCA
GCCGTGCTTGGTCGCCCGGCGTCCCCAGGCCGCTCCGGAGACTCACGGAACAGTGCAGAAACCA
ATAGAAGATAGTTGCTAGGACAGAAACTGCAGCCTGACCCTGTTGGACTCCACCTAAATGATGA
CTGCTGAGTCAAGGGAAGCCACGGGTCTATCCCCACAGGCTGCACAGGAGAAAGATGGTATAGT
CATTGTGAAGGTAGAAGAAGAAGACGAGGAAGACCACATGTGGGGGCAGGACGCTAGCCTTCAG
GAGACGCCACCACCCGACCCAGAGGTGTTCCGCCAACGGTTCAGGCGCTTCTGTTACCAGAACA
CTTTTGGGCCTCGAGAAGCTCTAAATCGACTAAAGGAACTTTGTCATCAGTGGCTTCGACCAGA
AGTCAACACCAAGGAACAGATCTTGGAGCTGTTGGTACTGGAGCAGTTCCTGTCCATCCTGCCC
AAAGAGCTGCAAGTGTGGCTGCAGGAGTACCGGCCTGACAGTGGAGAAGAGGCCGTGACTCTTC
TGGAAGACTTGGAACTTGATCTGTCAGGACAGCAGGTCCCAGGTCAAGTTCATGGGCCTGAGAT
GCTTGCCAGGGGTGTGGTGCCTCTGGATCCAGTTCAGGAGTCCTCAAGCTTCGACCATCATGAA
GCTGCCCAGTCTCATTTCAAGCATTCGTCTAGAAAGCCTCGTCTCTTATCACCCCGAGCTCTCC
CTGCCACCCACGTTCCTGCCCCTCAGCATGAGGGGAATCCCAGAGACCAGGCGATGGCATCTGC
ACTATTGACCGCAGATTCCCAGGCAATGGTGAAGATCGAGGACATGGCCGTGTCCCTCATCCTG
GAGGAATGGGGATGTCAGAACCTGGCTCGGAGGAATCTCAATAGGGACAGCAGGCAGATGAATT
TGGGAACTGTGTTTTCCCAGGGTTCTGAGAACAGGAATGGAAGTGAGTCAACCTCAAAAGCTGA
AGTCAAAGGAGATTCCACCTCACACGGGGAGATAGCAGGAAGATTCCAGAAAGAGTTTGGAGAG
AAGCGGGAACAGCAGGGCAGAGTAATTGAAAGGCAACAGAAAAATCCTGAAGAGAAAACTGGCA
AAGAGAAGAAAGCCCCTGGGCCACCTACAGCCAAGGAAAAGAAGCCCACCACAGGAGAGAGGGG
CCCAAGGGAGAAGGGTAAAGGTTTGGGAAGAAGCTTCAGCCTGAGTGCAAACTTTAATAATACT
CCCGAGGAGATTCCATCAGGAGCAAAGACTCATAGATGTGATGAGTGTGGGAAATGTTTCACAA
GAAGCTCAAGCCTTATCCGCCATAAAATCATCCACACTGGAGAGAAACCCTACGAATGTAATGA
GTGTGGGAAAGCCTTCAGTCTCAATTCAAACCTTGTCCTACATCAGCGAATCCACACAGGAGAG
AAACCGCATGAATGTAACGAGTGTGGCAAAGCCTTCAGTCATAGCTCGAATCTTATCCTGCACC
AGCGCATCCACTCTGGAGAGAAGCCCTACGAATGTAATGAGTGTGGCAAAGCCTTCAGCCAGAG
CTCAGACCTCACGAAGCACCAGAGAATCCATACGGGGGAGAAGCCCTATGAATGTAGTGAATGT
GGAAAAGCTTTCAACCGAAACTCATACCTTATTTTGCACCGGAGAATTCATACCCGAGAAAAGC
CCTACAAGTGCACTAAGTGTGGCAAGGCCTTCACCCGAAGCTCAACCCTCACACTGCACCATAG
AATCCATGCCAGAGAAAGAGCATCAGAATACAGCCCAGCCTCTCTGGATACCTTTGGAGCATTC
CTGAAAAGTTGTGTGTAAAGCAGGAGTGTGTCATCAAGCCATTTCCCCCCTTTTGTTTCTGGAA
TTATGTCAGACCTACGTGCCCATTGAGGGAAAAGTAATAGCACCATCCAATTGTTTGAGAAGTC
ACACTTCAGGATCCCTGAGAAGTACATCAACAGTGTCCTGTAATTCTTATAGTCCTTGCAAGGG
AAAGCTGGTCTTGTGGGTGTTCTTCCACTCAAGATAAAAGTGCACACACAATGTGTGTAAAACG
TCAAGCTTTCTAGTAATGGGTATAACTTTAAGATTTGCTTCCCAGCAACCACACCATGTAGTTG
ATGAGTCAAGATTAGCTCTGTGAATATTAAACTGAAGTTAAGAAGCCACTTGCTGCAAACAAGC
CTGTTATTTCTCAATGAAGAGAGATAGTTGATACAAAAACTACATTGGGACATGCTGCTCAAGC
AAGGTATATATCCAGAAGGTTGTATATCCGATCACTGGTAGCCTGCCAAAGCTATAGAAATCTA
GGACTGTGCTGGTCAGAATCAAACCAAAGATTTCTATCTCTTTCTGAAAGAGGGCATATGTACC
AGTTTGTAGTTCCAAGGACTGTAACAAATATGGAGAGCCCTGCACTCATCAGTGAGATCAGTCC
TACCTGCGGGAATAGCAATTCAAGATGCTTCTCTTCCTCTTCAACATCCCTAAAGCACTCTAGC
ACTCCTAAATGCACTCTCCACAAATTAGCACTTGATTGTATGGCATCTTTTAATCCTTCATAGT
TCAGTGTTGGAAGCTTTTATCAGTCACCACCACCTCCCCCAAAAAAGATGCTTCAGTTGTGAAG
AAATATAGTTCTGTTCCTGACAGCACAGCACTGGATGTCGTACTGAACACACACAAGGCACTCC
TGATGGACTTCTAACAGGACTATCATATTTGTGCTGGAGTCTGTGAATCATGTGAGTACCTGAA
CTGTGGTACCTCCAGACCTATAGGCCATACTGTACCGTATCCTAGGTCAGTGTTATTTTTGTCC
CAAATAAGCAGAAGCTTGGTTAACCACCTGCAGAGACTGCAAATGTGGATCAGCAAGCAGATGC
CACAGAATGTCAGAAACGCTTCCTGTCGTCCACTCACAGAAGAAAACCGTGAACACTAACTATA
AAGTTTTGTTTGTATGACATCATTCCACGGCAAAGATCTTGTTCCTGGCCAGAGTTCTTTTCAG
TCAGCTGCTGAATAGTGGTGTTTTGAGCACTTGCTGAGTTGTTCAAAACTTAGCTAATGCTGTT
CAAAAGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039089696 ⟹ XP_038945624

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	22,080,319 - 22,101,389 (+)	NCBI
mRatBN7.2	12	16,966,296 - 16,987,680 (+)	NCBI

RefSeq Acc Id:

XM_039089697 ⟹ XP_038945625

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	22,080,319 - 22,101,389 (+)	NCBI
mRatBN7.2	12	16,966,287 - 16,981,012 (+)	NCBI

RefSeq Acc Id:

XR_005491663

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	22,080,319 - 22,101,389 (+)	NCBI
mRatBN7.2	12	16,966,299 - 16,987,680 (+)	NCBI

RefSeq Acc Id:

XR_005491664

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	22,080,319 - 22,101,389 (+)	NCBI
mRatBN7.2	12	16,966,299 - 16,987,680 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001020931	(Get FASTA)	NCBI Sequence Viewer
	XP_038945624	(Get FASTA)	NCBI Sequence Viewer
	XP_038945625	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH99191	(Get FASTA)	NCBI Sequence Viewer
	EDL83888	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000051042
	ENSRNOP00000051042.3
	ENSRNOP00000081334
GenBank Protein	Q4KLI1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001020931 ⟸ NM_001025760

- UniProtKB:

Q4KLI1 (UniProtKB/Swiss-Prot), A6KSS2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDASLQETPPPDPEVFRQRFRRFCY
QNTFGPREALNRLKELCHQWLRPEVNTKEQILELLVLEQFLSILPKELQVWLQEYRPDSGEEAV
TLLEDLELDLSGQQVPGQVHGPEMLARGVVPLDPVQESSSFDHHEAAQSHFKHSSRKPRLLSPR
ALPATHVPAPQHEGNPRDQAMASALLTADSQAMVKIEDMAVSLILEEWGCQNLARRNLNRDSRQ
MNLGTVFSQGSENRNGSESTSKAEVKGDSTSHGEIAGRFQKEFGEKREQQGRVIERQQKNPEEK
TGKEKKAPGPPTAKEKKPTTGERGPREKGKGLGRSFSLSANFNNTPEEIPSGAKTHRCDECGKC
FTRSSSLIRHKIIHTGEKPYECNECGKAFSLNSNLVLHQRIHTGEKPHECNECGKAFSHSSNLI
LHQRIHSGEKPYECNECGKAFSQSSDLTKHQRIHTGEKPYECSECGKAFNRNSYLILHRRIHTR
EKPYKCTKCGKAFTRSSTLTLHHRIHARERASEYSPASLDTFGAFLKSCV

hide sequence

Ensembl Acc Id:

ENSRNOP00000051042 ⟸ ENSRNOT00000045379

RefSeq Acc Id:	XP_038945625 ⟸ XM_039089697
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038945624 ⟸ XM_039089696
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZS14 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000081334 ⟸ ENSRNOT00000099099

Protein Domains

C2H2-type KRAB SCAN box

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4KLI1-F1-model_v2	AlphaFold	Q4KLI1	1-562	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698490

Promoter ID:

EPDNEW_R9015

Type:

multiple initiation site

Name:

Zkscan1_1

Description:

zinc finger with KRAB and SCAN domains 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	19,231,075 - 19,231,135	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1560616	AgrOrtholog
BioCyc Gene	G2FUF-19827	BioCyc
Ensembl Genes	ENSRNOG00000001335	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000045379	ENTREZGENE
	ENSRNOT00000045379.4	UniProtKB/Swiss-Prot
	ENSRNOT00000099099	ENTREZGENE
Gene3D-CATH	1.10.4020.10	UniProtKB/Swiss-Prot
	6.10.140.140	UniProtKB/Swiss-Prot
	Classic Zinc Finger	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7383463	IMAGE-MGC_LOAD
InterPro	KRAB	UniProtKB/Swiss-Prot
	KRAB_dom_sf	UniProtKB/Swiss-Prot
	SCAN_dom	UniProtKB/Swiss-Prot
	SCAN_sf	UniProtKB/Swiss-Prot
	Znf_C2H2_sf	UniProtKB/Swiss-Prot
	Znf_C2H2_type	UniProtKB/Swiss-Prot
KEGG Report	rno:498160	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:116363	IMAGE-MGC_LOAD
NCBI Gene	498160	ENTREZGENE
PANTHER	TRANSCRIPTIONAL REPRESSOR PROTEIN YY	UniProtKB/Swiss-Prot
	ZINC FINGER PROTEIN 3	UniProtKB/Swiss-Prot
Pfam	KRAB	UniProtKB/Swiss-Prot
	SCAN	UniProtKB/Swiss-Prot
	zf-C2H2	UniProtKB/Swiss-Prot
PhenoGen	Zkscan1	PhenoGen
PROSITE	SCAN_BOX	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000001335	RatGTEx
SMART	KRAB	UniProtKB/Swiss-Prot
	SCAN	UniProtKB/Swiss-Prot
	ZnF_C2H2	UniProtKB/Swiss-Prot
Superfamily-SCOP	Retrovirus capsid dimerization domain-like	UniProtKB/Swiss-Prot
	SSF109640	UniProtKB/Swiss-Prot
	SSF57667	UniProtKB/Swiss-Prot
UniProt	A0A8I5ZS14	ENTREZGENE, UniProtKB/TrEMBL
	A6KSS2	ENTREZGENE, UniProtKB/TrEMBL
	Q4KLI1	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Zkscan1	zinc finger with KRAB and SCAN domains 1	MGC116363	zinc finger protein 36 (KOX 18)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	MGC116363	zinc finger protein 36 (KOX 18)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar