Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rnf182 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RNF182 mRNA | CTD | PMID:22079256 | Rnf182 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RNF182 mRNA | CTD | PMID:32109520 | Rnf182 | Rat | 4,4'-diaminodiphenylmethane | affects expression | ISO | Rnf182 (Mus musculus) | 6480464 | 4,4'-diaminodiphenylmethane affects the expression of RNF182 mRNA | CTD | PMID:18648102 | Rnf182 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | Rnf182 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of RNF182 exon | CTD | PMID:33297965 | Rnf182 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of RNF182 mRNA | CTD | PMID:24780913 | Rnf182 | Rat | acrylamide | decreases expression | ISO | Rnf182 (Mus musculus) | 6480464 | Acrylamide results in decreased expression of RNF182 mRNA | CTD | PMID:30807115 | Rnf182 | Rat | aflatoxin B1 | decreases methylation | ISO | RNF182 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of RNF182 gene | CTD | PMID:27153756 | Rnf182 | Rat | all-trans-retinoic acid | decreases expression | ISO | RNF182 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RNF182 mRNA | CTD | PMID:21934132|PMID:33167477 | Rnf182 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RNF182 mRNA | CTD | PMID:35163327 | Rnf182 | Rat | antirheumatic drug | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of RNF182 mRNA | CTD | PMID:24449571 | Rnf182 | Rat | arsane | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rnf182 | Rat | arsenic atom | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rnf182 | Rat | arsenous acid | decreases expression | ISO | Rnf182 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of RNF182 mRNA | CTD | PMID:35676786 | Rnf182 | Rat | benzo[a]pyrene | multiple interactions | ISO | Rnf182 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RNF182 mRNA] | CTD | PMID:22228805 | Rnf182 | Rat | benzo[a]pyrene | affects methylation | ISO | RNF182 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RNF182 5' UTR | CTD | PMID:27901495 | Rnf182 | Rat | benzo[a]pyrene | increases methylation | ISO | RNF182 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RNF182 3' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Rnf182 | Rat | benzo[a]pyrene | increases expression | ISO | Rnf182 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RNF182 mRNA | CTD | PMID:22228805 | Rnf182 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RNF182 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RNF182 mRNA | CTD | PMID:19150397 | Rnf182 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RNF182 mRNA | CTD | PMID:25181051|PMID:36779543 | Rnf182 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RNF182 mRNA | CTD | PMID:30816183|PMID:34947998 | Rnf182 | Rat | butanal | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of RNF182 mRNA | CTD | PMID:26079696 | Rnf182 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Rnf182 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of RNF182 intron | CTD | PMID:28392331 | Rnf182 | Rat | diarsenic trioxide | decreases expression | ISO | Rnf182 (Mus musculus) | 6480464 | Arsenic Trioxide results in decreased expression of RNF182 mRNA | CTD | PMID:35676786 | Rnf182 | Rat | dorsomorphin | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Rnf182 | Rat | doxorubicin | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of RNF182 mRNA | CTD | PMID:30031762 | Rnf182 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of RNF182 mRNA | CTD | PMID:30307764 | Rnf182 | Rat | fipronil | decreases expression | EXP | | 6480464 | fipronil results in decreased expression of RNF182 mRNA | CTD | PMID:34044035 | Rnf182 | Rat | folic acid | decreases expression | ISO | Rnf182 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of RNF182 mRNA | CTD | PMID:25629700 | Rnf182 | Rat | manganese atom | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rnf182 | Rat | manganese(0) | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rnf182 | Rat | manganese(II) chloride | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rnf182 | Rat | Monobutylphthalate | increases expression | EXP | | 6480464 | monobutyl phthalate results in increased expression of RNF182 mRNA | CTD | PMID:29162477 | Rnf182 | Rat | panobinostat | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Rnf182 | Rat | panobinostat | decreases expression | ISO | RNF182 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of RNF182 mRNA | CTD | PMID:26272509 | Rnf182 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of RNF182 mRNA | CTD | PMID:33387578 | Rnf182 | Rat | pentanal | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | pentanal results in increased expression of RNF182 mRNA | CTD | PMID:26079696 | Rnf182 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RNF182 mRNA | CTD | PMID:35163327 | Rnf182 | Rat | potassium chromate | decreases expression | ISO | RNF182 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of RNF182 mRNA | CTD | PMID:22079256 | Rnf182 | Rat | potassium chromate | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RNF182 mRNA | CTD | PMID:22079256 | Rnf182 | Rat | propanal | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of RNF182 mRNA | CTD | PMID:26079696 | Rnf182 | Rat | rotenone | decreases expression | ISO | RNF182 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of RNF182 mRNA | CTD | PMID:29955902 | Rnf182 | Rat | SB 431542 | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | Rnf182 | Rat | silicon dioxide | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of RNF182 mRNA | CTD | PMID:25895662 | Rnf182 | Rat | sodium arsenite | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Rnf182 | Rat | sodium arsenite | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of RNF182 mRNA | CTD | PMID:35954277 | Rnf182 | Rat | sodium arsenite | decreases expression | ISO | Rnf182 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of RNF182 mRNA | CTD | PMID:37682722 | Rnf182 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of RNF182 mRNA | CTD | PMID:19281266 | Rnf182 | Rat | sotorasib | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RNF182 mRNA | CTD | PMID:36139627 | Rnf182 | Rat | sulforaphane | decreases expression | ISO | RNF182 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of RNF182 mRNA | CTD | PMID:31838189 | Rnf182 | Rat | testosterone | decreases expression | ISO | RNF182 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of RNF182 mRNA | CTD | PMID:33359661 | Rnf182 | Rat | titanium dioxide | increases methylation | ISO | Rnf182 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of RNF182 gene | CTD | PMID:35295148 | Rnf182 | Rat | titanium dioxide | decreases methylation | ISO | Rnf182 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of RNF182 promoter | CTD | PMID:35295148 | Rnf182 | Rat | trametinib | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of RNF182 mRNA | CTD | PMID:36139627 | Rnf182 | Rat | trichostatin A | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of RNF182 mRNA | CTD | PMID:24935251 | Rnf182 | Rat | trichostatin A | multiple interactions | ISO | RNF182 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Rnf182 | Rat | trichostatin A | decreases expression | ISO | RNF182 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of RNF182 mRNA | CTD | PMID:24935251|PMID:26272509 | Rnf182 | Rat | valproic acid | affects expression | ISO | Rnf182 (Mus musculus) | 6480464 | Valproic Acid affects the expression of RNF182 mRNA | CTD | PMID:17292431 | Rnf182 | Rat | valproic acid | affects expression | ISO | RNF182 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RNF182 mRNA | CTD | PMID:25979313 | Rnf182 | Rat | valproic acid | increases expression | ISO | RNF182 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RNF182 mRNA | CTD | 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