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Gene: Lrrc14 (leucine rich repeat containing 14) Rattus norvegicus

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Symbol:

Lrrc14

Name:

leucine rich repeat containing 14

RGD ID:

1560202

Description:

Predicted to enable kinase binding activity. Predicted to be involved in negative regulation of NF-kappaB transcription factor activity and negative regulation of toll-like receptor signaling pathway. Predicted to be active in cytoplasm. Orthologous to human LRRC14 (leucine rich repeat containing 14); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

leucine-rich repeat-containing protein 14; MGC108882; similar to Leucine-rich repeat-containing 14

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LRRC14 (leucine rich repeat containing 14)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Lrrc14 (leucine rich repeat containing 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lrrc14 (leucine rich repeat containing 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LRRC14 (leucine rich repeat containing 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LRRC14 (leucine rich repeat containing 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lrrc14 (leucine rich repeat containing 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LRRC14 (leucine rich repeat containing 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LRRC14 (leucine rich repeat containing 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lrrc14 (leucine rich repeat containing 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	LRRC14 (leucine rich repeat containing 14)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Lrrc14 (leucine rich repeat containing 14)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch73-174h16.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	lrrc14	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	110,311,384 - 110,317,757 (+)	NCBI		GRCr8
mRatBN7.2	7	108,430,755 - 108,437,118 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	108,430,792 - 108,437,111 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	110,172,674 - 110,179,050 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	112,396,248 - 112,402,624 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	112,357,001 - 112,363,361 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	117,773,219 - 117,779,555 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	117,773,230 - 117,779,505 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	117,761,186 - 117,767,499 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	114,760,919 - 114,766,477 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	104,781,396 - 104,786,954 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc14	Rat	Baller-Gerold syndrome		ISO	LRRC14 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Baller-Gerold syndrome	ClinVar	PMID:12734318 more ...
Lrrc14	Rat	Recombinant Chromosome 8 Syndrome		ISO	LRRC14 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Recombinant 8 syndrome	ClinVar	PMID:31690835

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc14	Rat	1,2-dimethylhydrazine	increases expression	ISO	Lrrc14 (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in increased expression of LRRC14 mRNA	CTD	PMID:22206623
Lrrc14	Rat	17beta-estradiol	increases expression	ISO	Lrrc14 (Mus musculus)	6480464	Estradiol results in increased expression of LRRC14 mRNA	CTD	PMID:39298647
Lrrc14	Rat	2-methylcholine	affects expression	ISO	LRRC14 (Homo sapiens)	6480464	beta-methylcholine affects the expression of LRRC14 mRNA	CTD	PMID:21179406
Lrrc14	Rat	4,4'-sulfonyldiphenol	decreases methylation	ISO	Lrrc14 (Mus musculus)	6480464	bisphenol S results in decreased methylation of LRRC14 exon	CTD	PMID:33297965
Lrrc14	Rat	acrylamide	increases expression	EXP		6480464	Acrylamide results in increased expression of LRRC14 mRNA	CTD	PMID:28959563
Lrrc14	Rat	antirheumatic drug	increases expression	ISO	LRRC14 (Homo sapiens)	6480464	Antirheumatic Agents results in increased expression of LRRC14 mRNA	CTD	PMID:24449571
Lrrc14	Rat	arsane	multiple interactions	ISO	LRRC14 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of LRRC14 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of LRRC14 mRNA	CTD	PMID:39836092
Lrrc14	Rat	arsenic atom	multiple interactions	ISO	LRRC14 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of LRRC14 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of LRRC14 mRNA	CTD	PMID:39836092
Lrrc14	Rat	atrazine	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	Atrazine results in decreased expression of LRRC14 mRNA	CTD	PMID:22378314
Lrrc14	Rat	benzo[a]pyrene	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased expression of LRRC14 mRNA	CTD	PMID:20106945 and PMID:32234424
Lrrc14	Rat	benzo[a]pyrene	increases methylation	ISO	LRRC14 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of LRRC14 3' UTR	CTD	PMID:27901495
Lrrc14	Rat	benzo[a]pyrene	increases expression	ISO	Lrrc14 (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of LRRC14 mRNA	CTD	PMID:22228805
Lrrc14	Rat	beta-lapachone	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	beta-lapachone results in decreased expression of LRRC14 mRNA	CTD	PMID:38218311
Lrrc14	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of LRRC14 mRNA	CTD	PMID:25181051
Lrrc14	Rat	bisphenol A	increases expression	ISO	Lrrc14 (Mus musculus)	6480464	bisphenol A results in increased expression of LRRC14 mRNA	CTD	PMID:33221593
Lrrc14	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of LRRC14 mRNA	CTD	PMID:30816183 and PMID:32528016
Lrrc14	Rat	butanal	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	butyraldehyde results in decreased expression of LRRC14 mRNA	CTD	PMID:26079696
Lrrc14	Rat	cadmium dichloride	decreases expression	EXP		6480464	Cadmium Chloride results in decreased expression of LRRC14 mRNA	CTD	PMID:33453195
Lrrc14	Rat	cobalt dichloride	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	cobaltous chloride results in decreased expression of LRRC14 mRNA	CTD	PMID:19376846
Lrrc14	Rat	copper(II) sulfate	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	Copper Sulfate results in decreased expression of LRRC14 mRNA	CTD	PMID:19549813
Lrrc14	Rat	cyclosporin A	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	Cyclosporine results in decreased expression of LRRC14 mRNA	CTD	PMID:20106945
Lrrc14	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of LRRC14 mRNA	CTD	PMID:33387578
Lrrc14	Rat	leflunomide	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	leflunomide results in decreased expression of LRRC14 mRNA	CTD	PMID:28988120
Lrrc14	Rat	leflunomide	decreases expression	ISO	Lrrc14 (Mus musculus)	6480464	leflunomide results in decreased expression of LRRC14 mRNA	CTD	PMID:19751817
Lrrc14	Rat	manganese atom	multiple interactions	ISO	LRRC14 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of LRRC14 mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LRRC14 mRNA	CTD	PMID:39836092
Lrrc14	Rat	manganese(0)	multiple interactions	ISO	LRRC14 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of LRRC14 mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LRRC14 mRNA	CTD	PMID:39836092
Lrrc14	Rat	manganese(II) chloride	multiple interactions	ISO	LRRC14 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of LRRC14 mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of LRRC14 mRNA	CTD	PMID:39836092
Lrrc14	Rat	methylmercury chloride	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	methylmercuric chloride results in decreased expression of LRRC14 mRNA	CTD	PMID:28001369
Lrrc14	Rat	N-ethyl-N-nitrosourea	increases mutagenesis	ISO	Lrrc14 (Mus musculus)	6480464	Ethylnitrosourea results in increased mutagenesis of LRRC14 mRNA	CTD	PMID:27776689
Lrrc14	Rat	ochratoxin A	decreases expression	EXP		6480464	ochratoxin A results in decreased expression of LRRC14 mRNA	CTD	PMID:37162024
Lrrc14	Rat	ochratoxin A	increases methylation	EXP		6480464	ochratoxin A results in increased methylation of LRRC14 gene	CTD	PMID:37162024
Lrrc14	Rat	ozone	multiple interactions	ISO	LRRC14 (Homo sapiens)	6480464	[Air Pollutants results in increased abundance of Ozone] which affects the expression of LRRC14 mRNA	CTD	PMID:35430440
Lrrc14	Rat	paracetamol	increases expression	ISO	LRRC14 (Homo sapiens)	6480464	Acetaminophen results in increased expression of LRRC14 mRNA	CTD	PMID:22230336
Lrrc14	Rat	silicon dioxide	decreases expression	ISO	Lrrc14 (Mus musculus)	6480464	Silicon Dioxide results in decreased expression of LRRC14 mRNA	CTD	PMID:19073995 and PMID:33720480
Lrrc14	Rat	sodium arsenite	decreases expression	ISO	LRRC14 (Homo sapiens)	6480464	sodium arsenite results in decreased expression of LRRC14 mRNA	CTD	PMID:38568856
Lrrc14	Rat	sodium arsenite	multiple interactions	ISO	LRRC14 (Homo sapiens)	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of LRRC14 mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of LRRC14 mRNA	CTD	PMID:39836092
Lrrc14	Rat	Soman	decreases expression	EXP		6480464	Soman results in decreased expression of LRRC14 mRNA	CTD	PMID:19281266
Lrrc14	Rat	thioacetamide	decreases expression	EXP		6480464	Thioacetamide results in decreased expression of LRRC14 mRNA	CTD	PMID:34492290
Lrrc14	Rat	titanium dioxide	decreases methylation	ISO	Lrrc14 (Mus musculus)	6480464	titanium dioxide results in decreased methylation of LRRC14 gene	CTD	PMID:35295148
Lrrc14	Rat	Triptolide	increases expression	ISO	Lrrc14 (Mus musculus)	6480464	triptolide results in increased expression of LRRC14 mRNA	CTD	PMID:32835833
Lrrc14	Rat	triptonide	increases expression	ISO	Lrrc14 (Mus musculus)	6480464	triptonide results in increased expression of LRRC14 mRNA	CTD	PMID:33045310
Lrrc14	Rat	urethane	affects expression	ISO	LRRC14 (Homo sapiens)	6480464	Urethane affects the expression of LRRC14 mRNA	CTD	PMID:28818685
Lrrc14	Rat	valproic acid	increases methylation	ISO	LRRC14 (Homo sapiens)	6480464	Valproic Acid results in increased methylation of LRRC14 gene	CTD	PMID:29154799
Lrrc14	Rat	zoledronic acid	increases expression	ISO	LRRC14 (Homo sapiens)	6480464	zoledronic acid results in increased expression of LRRC14 mRNA	CTD	PMID:20977926

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc14	Rat	negative regulation of NF-kappaB transcription factor activity	involved_in	ISS	UniProtKB:Q15048	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Lrrc14	Rat	negative regulation of NF-kappaB transcription factor activity	involved_in	ISO	LRRC14 (Homo sapiens)	1624291	PMID:27426725	RGD	PMID:27426725
Lrrc14	Rat	negative regulation of toll-like receptor signaling pathway	involved_in	ISS	UniProtKB:Q15048	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Lrrc14	Rat	negative regulation of toll-like receptor signaling pathway	involved_in	IBA	PANTHER:PTN000369105 and UniProtKB:Q15048	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc14	Rat	negative regulation of toll-like receptor signaling pathway	involved_in	ISO	LRRC14 (Homo sapiens)	1624291	PMID:27426725	RGD	PMID:27426725
Lrrc14	Rat	negative regulation of toll-like receptor signaling pathway	involved_in	IEA	UniProtKB:Q15048 and ensembl:ENSP00000292524	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc14	Rat	cytoplasm	located_in	ISO	LRRC14 (Homo sapiens)	1624291	PMID:27426725	RGD	PMID:27426725
Lrrc14	Rat	cytoplasm	located_in	IEA	UniProtKB:Q15048 and ensembl:ENSP00000292524	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Lrrc14	Rat	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Lrrc14	Rat	cytoplasm	located_in	ISS	UniProtKB:Q15048	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Lrrc14	Rat	cytoplasm	is_active_in	IBA	MGI:1890541 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc14	Rat	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	1600115	GO_REF:0000044	UniProt	GO_REF:0000044

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Lrrc14	Rat	kinase binding	enables	IEA	UniProtKB:Q15048 and ensembl:ENSP00000292524	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Lrrc14	Rat	kinase binding	enables	IBA	PANTHER:PTN000369105 and UniProtKB:Q15048	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Lrrc14	Rat	kinase binding	enables	ISO	LRRC14 (Homo sapiens)	1624291	UniProtKB:O14920 more ...	RGD	PMID:27426725
Lrrc14	Rat	protein binding	enables	ISO	LRRC14 (Homo sapiens)	1624291	UniProtKB:Q13617 more ...	RGD	PMID:21145461 and PMID:33961781

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
5.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

PMID:27426725

Lrrc14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	110,311,384 - 110,317,757 (+)	NCBI		GRCr8
mRatBN7.2	7	108,430,755 - 108,437,118 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	108,430,792 - 108,437,111 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	110,172,674 - 110,179,050 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	112,396,248 - 112,402,624 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	112,357,001 - 112,363,361 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	117,773,219 - 117,779,555 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	117,773,230 - 117,779,505 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	117,761,186 - 117,767,499 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	114,760,919 - 114,766,477 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	104,781,396 - 104,786,954 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

LRRC14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	144,517,992 - 144,525,178 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	144,517,992 - 144,525,172 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	145,743,376 - 145,750,556 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	145,714,199 - 145,721,365 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	145,714,198 - 145,721,365	NCBI
Celera	8	141,919,071 - 141,926,237 (+)	NCBI		Celera
Cytogenetic Map	8	q24.3	NCBI
HuRef	8	140,856,834 - 140,864,047 (+)	NCBI		HuRef
CHM1_1	8	145,781,538 - 145,788,752 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	145,688,176 - 145,695,358 (+)	NCBI		T2T-CHM13v2.0

Lrrc14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	76,594,820 - 76,599,297 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	76,594,823 - 76,601,899 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	76,710,615 - 76,715,097 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	76,710,623 - 76,717,699 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	76,541,170 - 76,545,521 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	76,537,995 - 76,542,346 (+)	NCBI		MGSCv36	mm8
Celera	15	78,204,350 - 78,208,701 (+)	NCBI		Celera
Cytogenetic Map	15	D3	NCBI
cM Map	15	36.28	NCBI

Lrrc14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955454	3,142,636 - 3,146,470 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955454	3,142,621 - 3,146,470 (+)	NCBI	ChiLan1.0	ChiLan1.0

LRRC14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	162,011,911 - 162,014,202 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	137,539,464 - 137,543,633 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1 Ensembl	8	144,274,769 - 144,278,442 (+)	Ensembl	panpan1.1		panPan2

LRRC14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	37,937,437 - 37,941,202 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	37,937,111 - 37,941,703 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	37,897,740 - 37,901,510 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	38,410,725 - 38,414,495 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	38,408,727 - 38,414,495 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	38,102,671 - 38,106,439 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	38,211,083 - 38,214,853 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	38,687,562 - 38,691,332 (+)	NCBI		UU_Cfam_GSD_1.0

Lrrc14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	325,324 - 328,813 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936470	7,751,426 - 7,755,272 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	279,764 - 287,062 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	279,756 - 287,085 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	371,155 - 378,053 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRRC14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	138,732,276 - 138,736,348 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	138,734,046 - 138,735,804 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666039	1,115,429 - 1,122,666 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624735	12,337,564 - 12,345,260 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Lrrc14
30 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	399
Count of miRNA genes:	217
Interacting mature miRNAs:	256
Transcripts:	ENSRNOT00000021673
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	43747012	135012528	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	80221299	124373579	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	102297359	133492884	Rat
2298475	Eau6	Experimental allergic uveoretinitis QTL 6		0.0029	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	7	84257275	129257275	Rat
71114	Niddm14	Non-insulin dependent diabetes mellitus QTL 14	4.5		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	7	84257275	129257275	Rat
1357336	Gluco6	Glucose level QTL 6	3.4		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	7	94811326	116294265	Rat
1358361	Sradr5	Stress Responsive Adrenal Weight QTL 5	5.55		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	7	43747012	108555253	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	69736356	112729554	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	91412594	129807172	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	103146217	116738842	Rat
634331	Pia17	Pristane induced arthritis QTL 17	4.7		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	7	73829340	130221005	Rat
1358914	Bp266	Blood pressure QTL 266			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	44421311	118198041	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	83153392	128153392	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	64002457	135012528	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	90482196	135012528	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	81737938	126737938	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	80221299	109401111	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	96670164	135012528	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
2306821	Bp335	Blood pressure QTL 335		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	106571501	135012528	Rat
1558655	Swd4	Spike wave discharge measurement QTL 4	3.68	0.0002	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge severity grade (CMO:0001988)	7	86983365	131983365	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	924703	115097879	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	80221299	125221299	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	41333674	119109060	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	94811085	116738842	Rat
731174	Uae23	Urinary albumin excretion QTL 23	2.4	0.0042	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	7	104603555	135012528	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	68938720	113886318	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	80221299	112308525	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	75918751	120918751	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	68938720	113886318	Rat
2299163	Iddm34	Insulin dependent diabetes mellitus QTL 34	2.71		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	7	91281130	135012528	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	68938720	113886318	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	69736226	117455174	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	83591953	134666232	Rat

AW531492

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	108,437,385 - 108,437,536 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	117,779,823 - 117,779,973	NCBI	Rnor6.0
Rnor_5.0	7	117,767,802 - 117,767,952	UniSTS	Rnor5.0
RGSC_v3.4	7	114,766,794 - 114,766,944	UniSTS	RGSC3.4
Celera	7	104,787,271 - 104,787,421	UniSTS
RH 3.4 Map	7	792.9	UniSTS
Cytogenetic Map	7	q34	UniSTS

RH140300

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	108,436,677 - 108,436,860 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	117,779,115 - 117,779,297	NCBI	Rnor6.0
Rnor_5.0	7	117,767,094 - 117,767,276	UniSTS	Rnor5.0
RGSC_v3.4	7	114,766,086 - 114,766,268	UniSTS	RGSC3.4
Celera	7	104,786,563 - 104,786,745	UniSTS
RH 3.4 Map	7	795.5	UniSTS
Cytogenetic Map	7	q34	UniSTS

AW530743

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	7	108,437,071 - 108,437,265 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	117,779,509 - 117,779,702	NCBI	Rnor6.0
Rnor_5.0	7	117,767,488 - 117,767,681	UniSTS	Rnor5.0
RGSC_v3.4	7	114,766,480 - 114,766,673	UniSTS	RGSC3.4
Celera	7	104,786,957 - 104,787,150	UniSTS
RH 3.4 Map	7	793.5	UniSTS
Cytogenetic Map	7	q34	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001024354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001401224	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017595053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039079759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264131	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC092583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021673 ⟹ ENSRNOP00000021673

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	108,434,912 - 108,437,111 (+)	Ensembl
Rnor_6.0 Ensembl	7	117,773,948 - 117,779,505 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000077562 ⟹ ENSRNOP00000069176

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	108,430,806 - 108,437,100 (+)	Ensembl
Rnor_6.0 Ensembl	7	117,773,230 - 117,779,318 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097197 ⟹ ENSRNOP00000083734

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	7	108,430,792 - 108,437,100 (+)	Ensembl

RefSeq Acc Id:

NM_001024354 ⟹ NP_001019525

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,312,150 - 110,317,708 (+)	NCBI
mRatBN7.2	7	108,431,511 - 108,437,069 (+)	NCBI
Rnor_6.0	7	117,773,948 - 117,779,506 (+)	NCBI
Rnor_5.0	7	117,761,186 - 117,767,499 (+)	NCBI
RGSC_v3.4	7	114,760,919 - 114,766,477 (+)	RGD
Celera	7	104,781,396 - 104,786,954 (+)	RGD

Sequence:

show sequence

GTGTTTTGTATGCGGCTTCTCAGCTGGAACACTTTGGCAGTTTTGGCTTGGATCTTTGTGAATCCTGTGAATTTAAGACCTGGTGTCTCTGTGCAGTGGTTTCTCAGTGAAGAGAAGGTACCCGAATA
AGAAGCAAGGACCACAGAGGGGGCCTGTCTGCCCAGTCCAGCACCATGCACACGCTTGTGTTCCTCAGCACACGCCAGGTGCTTCAGTGCCAGCCAGCTGCCTGCCAGGCCTTGCCCCTGCTGCCCCG
AGAACTCTTCCCTCTGCTGTTCAAGGTGGCCTTCATGGACAAGAAGACAGCCGTGCTGCGTGAGCTGGTGCACACGTGGCCCTTTCCCCTCCTCAGTTTCCAGCAGCTGCTGCAGGAGTGTGCCCACT
GCAGTCGAGCCCTGCTGCAGGAACGGCTCAGCACAGAAAGCATGCAGGCTGTGATCCTGGGACTGACCGCCCGGATACATGCTCGAGAAGCAGAGGCTGGCACACAGCCCGTTTGCAGGAAGCATACA
CTGCGGGTACTGGACATGACTGGCCTCCTGGATGATGGTGTGGAGCAGGATCCAGGAACCATGAGCATGTGGGACTGTACAGCGGCGGTAGCCAGAACTTGTATTGCCCAGCAGCAGGTCGGGACTGC
TAAGCCAGGGCTGTCACCAGTCCCCGTGGAAATTCGTGTAGACCTTCGGGTAAACCGGGCCTCCTATACATTCCTTCGTGAGGCACTCCAGAGTAGTGTGGACAGCCTGCTGCGGCTCTGCTGCCGGG
ACCTCCGGGCTGAGGATCTGCCCATGCGTAACACTGTGGCCCTACTACAGCTTCTAGATGCAGGCTGTCTGCGCCGTATAGACCTGCGCTTCAATAACCTGGGCTTGCGTGGCCTGTCTGTCATTATC
CCACATGTGGCCCGCTTTCAGCACCTAGCCAGCCTGAGGCTGCATTATGTGCATGGGGACTCCAGACAGCCCTCCGTGGATGGTGAGGACAACTTTCGCTACTTCCTGGCCCAGATGGGCCGGTTCAT
CTGTCTTCGGGAGCTCAGCATTGGCTCTTCTCTCCTCTCAGGCAGGCTGGATCAACTGCTCAGCACCCTGCAGAGGCCCCTGGAAAGCCTAGAGCTGGCCTTCTGTGCACTGTTGCCTGAGGACCTAC
GCTTCCTGGCTCAGAGCTCTCATGCTGCCCACCTCAAAAAGCTGGACTTGAGTGGCAATGACTTGTCAGGCAACCAGCTGACACCCTTCCAGGGTCTGCTGCAGGCAGTAGCAGCCACACTGCTGCAT
CTTGAGCTGACTGAGTGCCAGATTGCTGATGCCCAGTTGTTGGCCACACTGCCCACCCTGACTCGCTGTGCCAGTCTCCGATACCTTGGTCTCTATGGCAACCCTTTGTCTATGGCAGGACTTAAAGA
GCTGCTTCGGGACTCTGTGATTCAGGCTGAGCTACGTACTGTGGTGCACCCTTTCCCTGTGGACTGCTATGAGGGTCTTCCTTGGCCGCCACCTGCCTCTGTCCTTCTGGAAGCCTCCATCAATGAGG
AGAAGTTTGCCCGTGTAGAAGCTGAGTTACACCAGCTGCTGTTAGCTTCAGGCCGTGCCCATGTACTCTGGACCACAGACATCTATGGCCGGCTGGCTGCAGACTATTTTAACCTCTGATCTCCAGGT
CTTGGTGAAGTCTTAGGTTTTCTGCAGAGTTTGCCTTTCTCCTGGGTACACCTTGAGTCACCTCTACTTTCTGCAGTGTCCTTCACCTGCTTATCTGGCTGCCTCTCGGTGTCTCAGGCCTGTGCTCC
CCTGTTCTGTATGATGTACTTGATGGCTCTGCTGAGTTGCGGTGTCTCTGTAGAAAACGGTTCCTGGACACATCCCATGCCCTCAGCAGGGGTGCAGTACATTGAGGTAGATGTTAGGATGATCTGCT
CCAGGGCATCTTTGGGTCTTATACTGTGTACCCTGCCTGGCACCCTAGTACCTGGCTCTGGAGGGTGTGAGTAAGGTACAAATGTGCAGTATCTGAAATGTGAATTTATGGGCTTTTTGAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001401224 ⟹ NP_001388153

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,394 - 110,317,757 (+)	NCBI
mRatBN7.2	7	108,430,755 - 108,437,118 (+)	NCBI

RefSeq Acc Id:

XM_006241862 ⟹ XP_006241924

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,450 - 110,317,757 (+)	NCBI
mRatBN7.2	7	108,430,802 - 108,437,118 (+)	NCBI
Rnor_6.0	7	117,773,530 - 117,779,555 (+)	NCBI
Rnor_5.0	7	117,761,186 - 117,767,499 (+)	NCBI

Sequence:

show sequence

GAGACCGCTGTGTCCTGTGTGCAGTAGCATCACCCAGAAGCAATTTTTTCTTGGGGACCAGGCCGGCTGCTTTCGTTTCCTCTTATGACAGGTGCTTGATTGGCTTGTCCTGTCGGTTAGGCAGCCCT
CCCAAGATTATCTTAAGGTAGAACCAGATCAAGGGTAGTCACCTGGGGTTTCCCAGGGACCGGTACCTTAAGGACTTGTACAAGGTGTTAGAAGTAAGCAAACCCCGGGTTTCTGCAGTCTTTCTGGT
CTCCACTCTTGTCCCGTGCTGCGGCTTTCCATAAGGCTTATTAGGCCTTGGTTTTCCATTGTGTTATAGGGTGAGAATTGTAACTGAAGTTCTGAGGGTAAGGTGTTTTGCCCACAGGAAGTCTACTG
ACCCTGTCTGTAGCAGGAATCATTCAGCCTCAGTGTGTTTTGTATGCGGCTTCTCAGCTGGAACACTTTGGCAGTTTTGGCTTGGATCTTTGTGAATCCTGTGAATTTAAGACCTGGTGTCTCTGTGC
AGTGGTTTCTCAGTGAAGAGAAGGTACCCGAATAAGAAGCAAGGACCACAGAGGCAAACATCCAAATCTGCTGGAACTCAATATTGGGCGGCCAGCTGGGGCCTGTCTGCCCAGTCCAGCACCATGCA
CACGCTTGTGTTCCTCAGCACACGCCAGGTGCTTCAGTGCCAGCCAGCTGCCTGCCAGGCCTTGCCCCTGCTGCCCCGAGAACTCTTCCCTCTGCTGTTCAAGGTGGCCTTCATGGACAAGAAGACAG
CCGTGCTGCGTGAGCTGGTGCACACGTGGCCCTTTCCCCTCCTCAGTTTCCAGCAGCTGCTGCAGGAGTGTGCCCACTGCAGTCGAGCCCTGCTGCAGGAACGGCTCAGCACAGAAAGCATGCAGGCT
GTGATCCTGGGACTGACCGCCCGGATACATGCTCGAGAAGCAGAGGCTGGCACACAGCCCGTTTGCAGGAAGCATACACTGCGGGTACTGGACATGACTGGCCTCCTGGATGATGGTGTGGAGCAGGA
TCCAGGAACCATGAGCATGTGGGACTGTACAGCGGCGGTAGCCAGAACTTGTATTGCCCAGCAGCAGGTCGGGACTGCTAAGCCAGGGCTGTCACCAGTCCCCGTGGAAATTCGTGTAGACCTTCGGG
TAAACCGGGCCTCCTATACATTCCTTCGTGAGGCACTCCAGAGTAGTGTGGACAGCCTGCTGCGGCTCTGCTGCCGGGACCTCCGGGCTGAGGATCTGCCCATGCGTAACACTGTGGCCCTACTACAG
CTTCTAGATGCAGGCTGTCTGCGCCGTATAGACCTGCGCTTCAATAACCTGGGCTTGCGTGGCCTGTCTGTCATTATCCCACATGTGGCCCGCTTTCAGCACCTAGCCAGCCTGAGGCTGCATTATGT
GCATGGGGACTCCAGACAGCCCTCCGTGGATGGTGAGGACAACTTTCGCTACTTCCTGGCCCAGATGGGCCGGTTCATCTGTCTTCGGGAGCTCAGCATTGGCTCTTCTCTCCTCTCAGGCAGGCTGG
ATCAACTGCTCAGCACCCTGCAGAGGCCCCTGGAAAGCCTAGAGCTGGCCTTCTGTGCACTGTTGCCTGAGGACCTACGCTTCCTGGCTCAGAGCTCTCATGCTGCCCACCTCAAAAAGCTGGACTTG
AGTGGCAATGACTTGTCAGGCAACCAGCTGACACCCTTCCAGGGTCTGCTGCAGGCAGTAGCAGCCACACTGCTGCATCTTGAGCTGACTGAGTGCCAGATTGCTGATGCCCAGTTGTTGGCCACACT
GCCCACCCTGACTCGCTGTGCCAGTCTCCGATACCTTGGTCTCTATGGCAACCCTTTGTCTATGGCAGGACTTAAAGAGCTGCTTCGGGACTCTGTGATTCAGGCTGAGCTACGTACTGTGGTGCACC
CTTTCCCTGTGGACTGCTATGAGGGTCTTCCTTGGCCGCCACCTGCCTCTGTCCTTCTGGAAGCCTCCATCAATGAGGAGAAGTTTGCCCGTGTAGAAGCTGAGTTACACCAGCTGCTGTTAGCTTCA
GGCCGTGCCCATGTACTCTGGACCACAGACATCTATGGCCGGCTGGCTGCAGACTATTTTAACCTCTGATCTCCAGGTCTTGGTGAAGTCTTAGGTTTTCTGCAGAGTTTGCCTTTCTCCTGGGTACA
CCTTGAGTCACCTCTACTTTCTGCAGTGTCCTTCACCTGCTTATCTGGCTGCCTCTCGGTGTCTCAGGCCTGTGCTCCCCTGTTCTGTATGATGTACTTGATGGCTCTGCTGAGTTGCGGTGTCTCTG
TAGAAAACGGTTCCTGGACACATCCCATGCCCTCAGCAGGGGTGCAGTACATTGAGGTAGATGTTAGGATGATCTGCTCCAGGGCATCTTTGGGTCTTATACTGTGTACCCTGCCTGGCACCCTAGTA
CCTGGCTCTGGAGGGTGTGAGTAAGGTACAAATGTGCAGTATCTGAAATGTGAATTTATGGGCTTTTTGATGTGTGTGTCCTAATTGGATGGGAAAGACTTACCTGCTTTTCTAGTGTT

hide sequence

RefSeq Acc Id:

XM_039079758 ⟹ XP_038935686

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,693 - 110,317,757 (+)	NCBI
mRatBN7.2	7	108,430,802 - 108,437,118 (+)	NCBI

RefSeq Acc Id:

XM_039079759 ⟹ XP_038935687

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,450 - 110,317,757 (+)	NCBI
mRatBN7.2	7	108,430,779 - 108,437,118 (+)	NCBI

RefSeq Acc Id:

XM_063264128 ⟹ XP_063120198

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,451 - 110,317,757 (+)	NCBI

RefSeq Acc Id:

XM_063264130 ⟹ XP_063120200

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,451 - 110,317,757 (+)	NCBI

RefSeq Acc Id:

XM_063264131 ⟹ XP_063120201

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,384 - 110,317,757 (+)	NCBI

RefSeq Acc Id:

XM_063264132 ⟹ XP_063120202

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,451 - 110,317,757 (+)	NCBI

RefSeq Acc Id:

XM_063264133 ⟹ XP_063120203

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	110,311,693 - 110,317,757 (+)	NCBI


Protein RefSeqs	NP_001019525	(Get FASTA)	NCBI Sequence Viewer
	NP_001388153	(Get FASTA)	NCBI Sequence Viewer
	XP_006241924	(Get FASTA)	NCBI Sequence Viewer
	XP_038935686	(Get FASTA)	NCBI Sequence Viewer
	XP_038935687	(Get FASTA)	NCBI Sequence Viewer
	XP_063120198	(Get FASTA)	NCBI Sequence Viewer
	XP_063120200	(Get FASTA)	NCBI Sequence Viewer
	XP_063120201	(Get FASTA)	NCBI Sequence Viewer
	XP_063120202	(Get FASTA)	NCBI Sequence Viewer
	XP_063120203	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH92583	(Get FASTA)	NCBI Sequence Viewer
	EDM15939	(Get FASTA)	NCBI Sequence Viewer
	EDM15940	(Get FASTA)	NCBI Sequence Viewer
	EDM15941	(Get FASTA)	NCBI Sequence Viewer
	EDM15942	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000069176
	ENSRNOP00000083734
	ENSRNOP00000098700
GenBank Protein	Q569B5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001019525 ⟸ NM_001024354
- Peptide Label:	isoform 2
- UniProtKB:	Q569B5 (UniProtKB/Swiss-Prot), A0A8L2UJL0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTAVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERLSTESMQAVILGLTARIHAREAEAGTQPVCRKHTLRVLDMTGLLDDGVE QDPGTMSMWDCTAAVARTCIAQQQVGTAKPGLSPVPVEIRVDLRVNRASYTFLREALQSSVDSLLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRIDLRFNNLGLRGLSVIIPHVARFQHLASLRLH YVHGDSRQPSVDGEDNFRYFLAQMGRFICLRELSIGSSLLSGRLDQLLSTLQRPLESLELAFCALLPEDLRFLAQSSHAAHLKKLDLSGNDLSGNQLTPFQGLLQAVAATLLHLELTECQIADAQLLA TLPTLTRCASLRYLGLYGNPLSMAGLKELLRDSVIQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFNL hide sequence

RefSeq Acc Id:	XP_006241924 ⟸ XM_006241862
- Peptide Label:	isoform X3
- UniProtKB:	Q569B5 (UniProtKB/Swiss-Prot), A0A8L2UJL0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MHTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTAVLRELVHTWPFPLLSFQQLLQECAHCSRALLQERLSTESMQAVILGLTARIHAREAEAGTQPVCRKHTLRVLDMTGLLDDGVE QDPGTMSMWDCTAAVARTCIAQQQVGTAKPGLSPVPVEIRVDLRVNRASYTFLREALQSSVDSLLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRIDLRFNNLGLRGLSVIIPHVARFQHLASLRLH YVHGDSRQPSVDGEDNFRYFLAQMGRFICLRELSIGSSLLSGRLDQLLSTLQRPLESLELAFCALLPEDLRFLAQSSHAAHLKKLDLSGNDLSGNQLTPFQGLLQAVAATLLHLELTECQIADAQLLA TLPTLTRCASLRYLGLYGNPLSMAGLKELLRDSVIQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELHQLLLASGRAHVLWTTDIYGRLAADYFNL hide sequence

Ensembl Acc Id:

ENSRNOP00000021673 ⟸ ENSRNOT00000021673

Ensembl Acc Id:

ENSRNOP00000069176 ⟸ ENSRNOT00000077562

RefSeq Acc Id:	XP_038935687 ⟸ XM_039079759
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2UJL0 (UniProtKB/TrEMBL)

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q569B5-F1-model_v2	AlphaFold	Q569B5	1-493	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13695445

Promoter ID:

EPDNEW_R5962

Type:

multiple initiation site

Name:

Lrrc14_1

Description:

leucine rich repeat containing 14

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	117,773,257 - 117,773,317	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-32906	BioCyc
Ensembl Genes	ENSRNOG00000016128	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000077562	ENTREZGENE
	ENSRNOT00000097197	ENTREZGENE
	ENSRNOT00000173835	ENTREZGENE
Gene3D-CATH	3.80.10.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7376401	IMAGE-MGC_LOAD
InterPro	Leu-rich_rpt	UniProtKB/Swiss-Prot
	LRR_dom_sf	UniProtKB/Swiss-Prot
	PRAME_domain	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108882	IMAGE-MGC_LOAD
NCBI Gene	500900	ENTREZGENE
PANTHER	PTHR14224:SF9	UniProtKB/Swiss-Prot
	SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3	UniProtKB/Swiss-Prot
Pfam	LRR_6	UniProtKB/Swiss-Prot
PhenoGen	Lrrc14	PhenoGen
RatGTEx	ENSRNOG00000016128	RatGTEx
Superfamily-SCOP	RNI-like	UniProtKB/Swiss-Prot
UniProt	A0A0G2JUP6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZZT2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2UJL0	ENTREZGENE, UniProtKB/TrEMBL
	LRC14_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Lrrc14	leucine rich repeat containing 14	MGC108882	similar to Leucine-rich repeat-containing 14	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-02-09	MGC108882	similar to Leucine-rich repeat-containing 14			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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