Ranbp2 (RAN binding protein 2) - Rat Genome Database

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Gene: Ranbp2 (RAN binding protein 2) Rattus norvegicus
Analyze
Symbol: Ranbp2
Name: RAN binding protein 2
RGD ID: 1560047
Description: Predicted to enable SUMO ligase activity and small GTPase binding activity. Predicted to contribute to GTPase activator activity. Involved in response to amphetamine. Located in cytoplasmic periphery of the nuclear pore complex. Part of nuclear pore cytoplasmic filaments. Human ortholog(s) of this gene implicated in brain disease and inflammatory myofibroblastic tumor. Orthologous to human RANBP2 (RAN binding protein 2); PARTICIPATES IN CRM1 export pathway; mitochondria transport pathway; RNA transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; DDT.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: E3 SUMO-protein ligase RanBP2; LOC294429; RGD1560047; similar to Ran-binding protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82026,984,520 - 27,036,573 (+)NCBIGRCr8
mRatBN7.22026,442,156 - 26,493,481 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2026,442,217 - 26,493,481 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2027,444,577 - 27,495,869 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02026,830,924 - 26,882,082 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02027,578,942 - 27,630,203 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02028,027,054 - 28,076,664 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.02028,365,538 - 28,375,676 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2028,365,988 - 28,375,791 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2028,027,054 - 28,076,664 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02029,846,539 - 29,896,149 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02030,181,409 - 30,191,111 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42037,271,467 - 37,322,723 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2027,892,535 - 27,943,825 (+)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. Aslanukov A, etal., PLoS Genet. 2006 Oct;2(10):e177. Epub 2006 Sep 1.
2. Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Cho KI, etal., Cell Mol Life Sci. 2012 Oct;69(20):3511-27. doi: 10.1007/s00018-012-1071-9. Epub 2012 Jul 21.
3. RanGTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex. Delphin C, etal., Mol Biol Cell. 1997 Dec;8(12):2379-90.
4. SAGE analysis highlights the importance of p53csv, ddx5, mapkapk2 and ranbp2 to multiple myeloma tumorigenesis. Felix RS, etal., Cancer Lett. 2009 Jun 8;278(1):41-8. doi: 10.1016/j.canlet.2008.12.022. Epub 2009 Jan 25.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Cellular distribution of AMPA receptor subunits and mGlu5 following acute and repeated administration of morphine or methamphetamine. Herrold AA, etal., J Neurochem. 2013 Aug;126(4):503-17. doi: 10.1111/jnc.12323. Epub 2013 Jun 18.
7. Vasopressin V1a receptor is required for nucleocytoplasmic transport of mineralocorticoid receptor. Hori K, etal., Am J Physiol Renal Physiol. 2012 Oct;303(7):F1080-8. doi: 10.1152/ajprenal.00052.2012. Epub 2012 Jul 18.
8. Regulation of mitochondrial transport in neurons. Lin MY and Sheng ZH, Exp Cell Res. 2015 May 15;334(1):35-44. doi: 10.1016/j.yexcr.2015.01.004. Epub 2015 Jan 19.
9. Fusion of ALK to the Ran-binding protein 2 (RANBP2) gene in inflammatory myofibroblastic tumor. Ma Z, etal., Genes Chromosomes Cancer. 2003 May;37(1):98-105.
10. A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Mahajan R, etal., Cell. 1997 Jan 10;88(1):97-107.
11. Mammalian karyopherin alpha 1 beta and alpha 2 beta heterodimers: alpha 1 or alpha 2 subunit binds nuclear localization signal and beta subunit interacts with peptide repeat-containing nucleoporins. Moroianu J, etal., Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6532-6.
12. Mice lacking Ran binding protein 1 are viable and show male infertility. Nagai M, etal., FEBS Lett. 2011 Mar 9;585(5):791-6. doi: 10.1016/j.febslet.2011.02.002. Epub 2011 Feb 26.
13. Postage for the messenger: designating routes for nuclear mRNA export. Natalizio BJ and Wente SR, Trends Cell Biol. 2013 Aug;23(8):365-73. doi: 10.1016/j.tcb.2013.03.006. Epub 2013 Apr 11.
14. Infection-triggered familial or recurrent cases of acute necrotizing encephalopathy caused by mutations in a component of the nuclear pore, RANBP2. Neilson DE, etal., Am J Hum Genet. 2009 Jan;84(1):44-51. doi: 10.1016/j.ajhg.2008.12.009.
15. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. GOA pipeline RGD automated data pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. Parkin ubiquitinates and promotes the degradation of RanBP2. Um JW, etal., J Biol Chem. 2006 Feb 10;281(6):3595-603. Epub 2005 Dec 6.
21. Nup358, a cytoplasmically exposed nucleoporin with peptide repeats, Ran-GTP binding sites, zinc fingers, a cyclophilin A homologous domain, and a leucine-rich region. Wu J, etal., J Biol Chem. 1995 Jun 9;270(23):14209-13.
Additional References at PubMed
PMID:7603572   PMID:11792325   PMID:11839768   PMID:15378033   PMID:15608651   PMID:16688858   PMID:17098863   PMID:17264123   PMID:17887960   PMID:18394993   PMID:19946888   PMID:20386726  
PMID:20676357   PMID:22155184   PMID:25002582   PMID:25294810  


Genomics

Comparative Map Data
Ranbp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82026,984,520 - 27,036,573 (+)NCBIGRCr8
mRatBN7.22026,442,156 - 26,493,481 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2026,442,217 - 26,493,481 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2027,444,577 - 27,495,869 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02026,830,924 - 26,882,082 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02027,578,942 - 27,630,203 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02028,027,054 - 28,076,664 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.02028,365,538 - 28,375,676 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2028,365,988 - 28,375,791 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2028,027,054 - 28,076,664 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02029,846,539 - 29,896,149 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02030,181,409 - 30,191,111 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42037,271,467 - 37,322,723 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2027,892,535 - 27,943,825 (+)NCBICelera
Cytogenetic Map20q11NCBI
RANBP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382108,719,482 - 109,842,301 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2108,719,482 - 108,785,810 (+)EnsemblGRCh38hg38GRCh38
GRCh372109,335,938 - 109,402,265 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362108,702,369 - 108,768,699 (+)NCBINCBI36Build 36hg18NCBI36
Build 342108,794,454 - 108,859,768NCBI
Celera2103,645,916 - 103,712,243 (+)NCBICelera
Cytogenetic Map2q13NCBI
HuRef2102,934,349 - 103,000,733 (+)NCBIHuRef
CHM1_12109,340,280 - 109,406,595 (+)NCBICHM1_1
T2T-CHM13v2.02109,180,084 - 110,303,989 (+)NCBIT2T-CHM13v2.0
Ranbp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391058,282,674 - 58,329,977 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1058,282,742 - 58,330,178 (+)EnsemblGRCm39 Ensembl
GRCm381058,446,852 - 58,494,155 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1058,446,920 - 58,494,356 (+)EnsemblGRCm38mm10GRCm38
MGSCv371057,909,600 - 57,956,903 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361057,842,209 - 57,889,512 (+)NCBIMGSCv36mm8
Celera1059,184,895 - 59,203,874 (+)NCBICelera
Celera712,211,992 - 12,212,429 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1029.34NCBI
Ranbp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547012,180,544 - 12,249,555 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547012,180,426 - 12,247,737 (+)NCBIChiLan1.0ChiLan1.0
LOC100989340
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21220,849,954 - 20,915,591 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A20,852,719 - 20,920,058 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A94,961,024 - 95,029,437 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A110,010,961 - 110,039,769 (+)NCBIpanpan1.1PanPan1.1panPan2
RANBP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11035,088,175 - 35,181,248 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1035,088,872 - 35,181,129 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1035,010,394 - 35,103,514 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01035,940,061 - 36,033,454 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1035,940,082 - 36,033,437 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11035,669,581 - 35,762,815 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01035,952,703 - 36,045,859 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01036,144,312 - 36,238,211 (-)NCBIUU_Cfam_GSD_1.0
Ranbp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629292,063,973 - 92,136,842 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936829261,129 - 332,999 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936829261,017 - 333,910 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100511376
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,531,359 - 47,601,495 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1347,531,362 - 47,601,328 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,693,982 - 49,735,050 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RANBP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11412,250,986 - 12,318,801 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1412,251,007 - 12,319,735 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660807,392,456 - 7,462,274 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101698338
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474911,862,760 - 11,923,958 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474911,862,670 - 11,923,291 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ranbp2
136 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:274
Count of miRNA genes:86
Interacting mature miRNAs:114
Transcripts:ENSRNOT00000001044, ENSRNOT00000071386
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat

Markers in Region
RH133637  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22026,493,023 - 26,493,220 (+)MAPPERmRatBN7.2
Rnor_6.02028,076,207 - 28,076,403NCBIRnor6.0
Rnor_5.02029,895,692 - 29,895,888UniSTSRnor5.0
RGSC_v3.42037,271,728 - 37,271,924UniSTSRGSC3.4
Celera2027,943,368 - 27,943,564UniSTS
Cytogenetic Map20q11UniSTS
RH136086  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22026,491,655 - 26,492,359 (+)MAPPERmRatBN7.2
Rnor_6.02028,074,839 - 28,075,542NCBIRnor6.0
Rnor_5.02029,894,324 - 29,895,027UniSTSRnor5.0
RGSC_v3.42037,272,589 - 37,273,292UniSTSRGSC3.4
Celera2027,941,999 - 27,942,703UniSTS
Cytogenetic Map20q11UniSTS
Ranbp2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22026,471,991 - 26,473,458 (+)MAPPERmRatBN7.2
Rnor_6.02028,055,177 - 28,056,643NCBIRnor6.0
Rnor_5.02029,874,662 - 29,876,128UniSTSRnor5.0
RGSC_v3.42037,291,490 - 37,292,956UniSTSRGSC3.4
Celera2027,922,329 - 27,923,795UniSTS
Cytogenetic Map20q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
18 20 66 165 140 138 76 49 76 12 327 159 125 58 94 62

Sequence


Ensembl Acc Id: ENSRNOT00000001044   ⟹   ENSRNOP00000001044
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2026,442,217 - 26,493,481 (+)Ensembl
Rnor_6.0 Ensembl2028,027,126 - 28,075,723 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000071386   ⟹   ENSRNOP00000063941
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2026,442,217 - 26,493,481 (+)Ensembl
Rnor_6.0 Ensembl2028,027,054 - 28,076,664 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000089619
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2028,365,988 - 28,375,791 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114220   ⟹   ENSRNOP00000077936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2026,442,217 - 26,493,481 (+)Ensembl
RefSeq Acc Id: NM_001191604   ⟹   NP_001178533
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82026,985,314 - 27,036,573 (+)NCBI
mRatBN7.22026,442,217 - 26,493,481 (+)NCBI
Rnor_6.02028,027,054 - 28,076,664 (+)NCBI
Rnor_5.02029,846,539 - 29,896,149 (+)NCBI
Celera2027,892,535 - 27,943,825 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098597   ⟹   XP_038954525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82026,984,520 - 27,036,567 (+)NCBI
mRatBN7.22026,442,156 - 26,493,481 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001178533 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954525 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001044.6
  ENSRNOP00000063941.2
  ENSRNOP00000077936.1
RefSeq Acc Id: NP_001178533   ⟸   NM_001191604
- UniProtKB: M0R3M4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063941   ⟸   ENSRNOT00000071386
Ensembl Acc Id: ENSRNOP00000001044   ⟸   ENSRNOT00000001044
RefSeq Acc Id: XP_038954525   ⟸   XM_039098597
- Peptide Label: isoform X1
- UniProtKB: A0A8I5YC36 (UniProtKB/TrEMBL),   M0R3M4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077936   ⟸   ENSRNOT00000114220
Protein Domains
PPIase cyclophilin-type   RanBD1   RanBP2-type

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701581
Promoter ID:EPDNEW_R12105
Type:initiation region
Name:Ranbp2_1
Description:RAN binding protein 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02028,027,038 - 28,027,098EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560047 AgrOrtholog
BioCyc Gene G2FUF-3785 BioCyc
Ensembl Genes ENSRNOG00000000796 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000056428 Ensembl
Ensembl Transcript ENSRNOT00000001044.7 UniProtKB/TrEMBL
  ENSRNOT00000071386.4 UniProtKB/TrEMBL
  ENSRNOT00000114220.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.40.100.10 UniProtKB/TrEMBL
  Zinc finger, RanBP2-type UniProtKB/TrEMBL
InterPro Cyclophilin-like_dom UniProtKB/TrEMBL
  IR1-M UniProtKB/TrEMBL
  Pep-Pro_Isoase_cyclophilin_CS UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  PPIase_cyclophilin UniProtKB/TrEMBL
  RanBP UniProtKB/TrEMBL
  RanBP1-like UniProtKB/TrEMBL
  TPR-like_helical UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
  Znf_RanBP2 UniProtKB/TrEMBL
  Znf_RanBP2_sf UniProtKB/TrEMBL
NCBI Gene 294429 ENTREZGENE
PANTHER E3 SUMO-PROTEIN LIGASE RANBP2 UniProtKB/TrEMBL
  PTHR23138 UniProtKB/TrEMBL
Pfam IR1-M UniProtKB/TrEMBL
  Pro_isomerase UniProtKB/TrEMBL
  Ran_BP1 UniProtKB/TrEMBL
  zf-RanBP UniProtKB/TrEMBL
PhenoGen Ranbp2 PhenoGen
PRINTS CSAPPISMRASE UniProtKB/TrEMBL
PROSITE CSA_PPIASE_1 UniProtKB/TrEMBL
  CSA_PPIASE_2 UniProtKB/TrEMBL
  RANBD1 UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
  ZF_RANBP2_1 UniProtKB/TrEMBL
  ZF_RANBP2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000796 RatGTEx
  ENSRNOG00000056428 RatGTEx
SMART RanBD UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
  ZnF_RBZ UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
  SSF50891 UniProtKB/TrEMBL
  SSF90209 UniProtKB/TrEMBL
UniProt A0A8I5YC36 ENTREZGENE, UniProtKB/TrEMBL
  D4A054_RAT UniProtKB/TrEMBL
  M0R3M4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-28 Ranbp2  RAN binding protein 2  RGD1560047_predicted  similar to Ran-binding protein 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1560047_predicted  similar to Ran-binding protein 2 (predicted)  LOC294429  similar to Ran-binding protein 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC294429  similar to Ran-binding protein 2      Symbol and Name status set to provisional 70820 PROVISIONAL