Tigar (TP53 induced glycolysis regulatory phosphatase) - Rat Genome Database

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Gene: Tigar (TP53 induced glycolysis regulatory phosphatase) Rattus norvegicus
Analyze
Symbol: Tigar
Name: TP53 induced glycolysis regulatory phosphatase
RGD ID: 1560038
Description: Predicted to enable fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in several processes, including cellular response to cobalt ion; regulation of nucleobase-containing compound metabolic process; and response to ischemia. Predicted to act upstream of or within several processes, including fructose 2,6-bisphosphate metabolic process; negative regulation of metabolic process; and positive regulation of cardiac muscle cell apoptotic process. Predicted to be located in mitochondrial outer membrane and nucleus. Predicted to be active in cytosol. Orthologous to human TIGAR (TP53 induced glycolysis regulatory phosphatase); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fructose-2,6-bisphosphatase TIGAR; hypothetical protein LOC502894; LOC502894; TP53-induced glycolysis and apoptosis regulator; uncharacterized protein LOC502894
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Tigar-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84161,613,306 - 161,632,248 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4161,613,306 - 161,632,229 (-)EnsemblGRCr8
mRatBN7.24159,927,136 - 159,946,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl687,509,809 - 87,510,466 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl4159,927,139 - 159,946,029 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4166,156,946 - 166,175,860 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04161,939,848 - 161,958,766 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04160,573,896 - 160,592,815 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04159,635,145 - 159,654,108 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4159,635,153 - 159,654,063 (-)Ensemblrn6Rnor6.0
Rnor_5.04231,948,786 - 231,966,869 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44163,481,393 - 163,502,412 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4148,642,195 - 148,661,115 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-colchicine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
actinomycin D  (ISO)
adefovir pivoxil  (ISO)
adenine  (ISO)
aflatoxin B1  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
brequinar  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cantharidin  (ISO)
captan  (ISO)
carbamazepine  (ISO)
chloroacetaldehyde  (ISO)
chlorpyrifos  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethyl methanesulfonate  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
hydrogen peroxide  (ISO)
ifosfamide  (ISO)
ivermectin  (ISO)
kainic acid  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methoxyacetic acid  (ISO)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
NADP zwitterion  (EXP,ISO)
NADP(+)  (EXP,ISO)
nickel atom  (ISO)
niclosamide  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
phenylmercury acetate  (ISO)
potassium bromate  (ISO)
progesterone  (ISO)
promegestone  (ISO)
propanal  (ISO)
quercetin  (ISO)
reactive oxygen species  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
Triptolide  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA,ISO)
cytosol  (IBA,IEA,ISO)
mitochondrial outer membrane  (IEA,ISO)
mitochondrion  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16839880   PMID:19015259   PMID:20935145   PMID:22044588   PMID:23185017   PMID:23726973   PMID:24872551   PMID:25928429   PMID:31160088   PMID:31317559   PMID:33858654  


Genomics

Comparative Map Data
Tigar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84161,613,306 - 161,632,248 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4161,613,306 - 161,632,229 (-)EnsemblGRCr8
mRatBN7.24159,927,136 - 159,946,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl687,509,809 - 87,510,466 (+)EnsemblmRatBN7.2
mRatBN7.2 Ensembl4159,927,139 - 159,946,029 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4166,156,946 - 166,175,860 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04161,939,848 - 161,958,766 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04160,573,896 - 160,592,815 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04159,635,145 - 159,654,108 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4159,635,153 - 159,654,063 (-)Ensemblrn6Rnor6.0
Rnor_5.04231,948,786 - 231,966,869 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44163,481,393 - 163,502,412 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4148,642,195 - 148,661,115 (-)NCBICelera
Cytogenetic Map4q42NCBI
TIGAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38124,321,213 - 4,360,028 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl124,307,763 - 4,360,028 (+)Ensemblhg38GRCh38
GRCh37124,430,379 - 4,469,194 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,300,620 - 4,339,455 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34124,300,631 - 4,332,599NCBI
Celera126,052,425 - 6,091,264 (+)NCBICelera
Cytogenetic Map12p13.32NCBI
HuRef124,287,018 - 4,325,825 (+)NCBIHuRef
CHM1_1124,429,992 - 4,468,805 (+)NCBICHM1_1
T2T-CHM13v2.0124,327,996 - 4,366,805 (+)NCBIT2T-CHM13v2.0
Tigar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396127,062,079 - 127,086,564 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6127,062,079 - 127,086,520 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm386127,085,116 - 127,109,552 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6127,085,116 - 127,109,557 (-)Ensemblmm10GRCm38
MGSCv376127,035,134 - 127,059,570 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366127,052,982 - 127,075,160 (-)NCBIMGSCv36mm8
MGSCv366127,984,031 - 128,005,972 (-)NCBIMGSCv36mm8
Celera6128,766,834 - 128,786,116 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map661.92NCBI
Tigar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554132,129,678 - 2,154,380 (+)Ensembl
ChiLan1.0NW_0049554132,129,719 - 2,153,873 (+)NCBIChiLan1.0ChiLan1.0
TIGAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2109,860,833 - 9,893,058 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1129,857,630 - 9,896,658 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0124,429,945 - 4,462,142 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1124,353,272 - 4,386,758 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl124,353,272 - 4,385,380 (+)EnsemblpanPan2panpan1.1
TIGAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12740,521,751 - 40,549,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2740,523,314 - 40,549,332 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha276,132,902 - 6,160,282 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02740,877,557 - 40,905,336 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2740,877,558 - 40,905,335 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12740,815,806 - 40,843,030 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02740,791,244 - 40,818,291 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,543,778 - 5,570,944 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tigar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945104,632,126 - 104,665,630 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366064,518,584 - 4,540,114 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366064,518,525 - 4,540,109 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIGAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl566,044,686 - 66,067,377 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1566,044,679 - 66,067,571 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2568,266,609 - 68,289,947 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TIGAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1114,354,911 - 4,381,762 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl114,355,053 - 4,381,273 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660633,861,799 - 3,888,740 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tigar
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248601,417,131 - 1,457,717 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248601,416,419 - 1,455,953 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tigar
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1620,799,726 - 20,814,642 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tigar
76 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4157292416184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155834926184426481Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155834926184426481Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4160623982184426481Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4148834094168870974Rat

Markers in Region
D4Mit25  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24159,940,316 - 159,940,457 (+)MAPPERmRatBN7.2
Rnor_6.04159,648,325 - 159,648,465NCBIRnor6.0
Rnor_5.04231,953,550 - 231,953,690UniSTSRnor5.0
RGSC_v3.44163,495,152 - 163,495,293RGDRGSC3.4
RGSC_v3.44163,495,153 - 163,495,293UniSTSRGSC3.4
Celera4148,655,370 - 148,655,510UniSTS
RGSC_v3.14163,740,089 - 163,740,229RGD
RH 3.4 Map41003.6RGD
RH 3.4 Map41003.6UniSTS
Cytogenetic Map4q42UniSTS
D4Got310  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr84161,626,889 - 161,627,079 (+)Marker Load Pipeline
mRatBN7.24159,940,720 - 159,940,910 (+)MAPPERmRatBN7.2
Rnor_6.04159,648,729 - 159,648,916NCBIRnor6.0
Rnor_5.04231,953,099 - 231,953,286UniSTSRnor5.0
RGSC_v3.44163,495,557 - 163,496,365UniSTSRGSC3.4
RGSC_v3.44163,495,557 - 163,495,744UniSTSRGSC3.4
Celera4148,655,774 - 148,655,961UniSTS
Cytogenetic Map4q42UniSTS
RH128614  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24159,927,286 - 159,927,487 (+)MAPPERmRatBN7.2
Rnor_6.04159,635,296 - 159,635,496NCBIRnor6.0
Rnor_5.04231,966,518 - 231,966,718UniSTSRnor5.0
RGSC_v3.44163,481,539 - 163,481,739UniSTSRGSC3.4
Celera4148,642,341 - 148,642,541UniSTS
RH 3.4 Map41009.1UniSTS
Cytogenetic Map4q42UniSTS
BF386144  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24159,928,629 - 159,928,796 (-)MAPPERmRatBN7.2
mRatBN7.24159,928,629 - 159,928,796 (+)MAPPERmRatBN7.2
mRatBN7.2687,510,667 - 87,510,834 (-)MAPPERmRatBN7.2
mRatBN7.2687,510,667 - 87,510,834 (+)MAPPERmRatBN7.2
Rnor_6.0691,332,590 - 91,332,756NCBIRnor6.0
Rnor_6.04159,636,639 - 159,636,805NCBIRnor6.0
Rnor_5.04231,965,209 - 231,965,375UniSTSRnor5.0
Rnor_5.06100,794,516 - 100,794,682UniSTSRnor5.0
RGSC_v3.44163,482,882 - 163,483,048UniSTSRGSC3.4
RGSC_v3.4691,001,278 - 91,001,444UniSTSRGSC3.4
Celera686,015,520 - 86,015,686UniSTS
Celera4148,643,684 - 148,643,850UniSTS
RH 3.4 Map6549.8UniSTS
Cytogenetic Map4q42UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 91 59 6 355 191 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000091662   ⟹   ENSRNOP00000074722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4161,613,306 - 161,632,229 (-)Ensembl
mRatBN7.2 Ensembl4159,927,144 - 159,946,025 (-)Ensembl
Rnor_6.0 Ensembl4159,635,153 - 159,654,063 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098356   ⟹   ENSRNOP00000088153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4159,927,143 - 159,946,029 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111057   ⟹   ENSRNOP00000092807
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4159,927,139 - 159,945,993 (-)Ensembl
RefSeq Acc Id: NM_001025064   ⟹   NP_001020235
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,613,306 - 161,632,229 (-)NCBI
mRatBN7.24159,927,136 - 159,946,061 (-)NCBI
Rnor_6.04159,635,150 - 159,654,063 (-)NCBI
Rnor_5.04231,948,786 - 231,966,869 (+)NCBI
RGSC_v3.44163,481,393 - 163,502,412 (-)RGD
Celera4148,642,195 - 148,661,115 (-)RGD
Sequence:
RefSeq Acc Id: NM_001395051   ⟹   NP_001381980
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,613,306 - 161,632,229 (-)NCBI
mRatBN7.24159,927,136 - 159,946,061 (-)NCBI
RefSeq Acc Id: XM_039108258   ⟹   XP_038964186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,613,311 - 161,632,248 (-)NCBI
mRatBN7.24159,927,138 - 159,946,077 (-)NCBI
RefSeq Acc Id: NP_001020235   ⟸   NM_001025064
- Peptide Label: isoform 2
- UniProtKB: Q566D2 (UniProtKB/TrEMBL),   A0A8I6A442 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074722   ⟸   ENSRNOT00000091662
RefSeq Acc Id: XP_038964186   ⟸   XM_039108258
- Peptide Label: isoform X1
- UniProtKB: Q566D2 (UniProtKB/TrEMBL),   A0A8I6A442 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000088153   ⟸   ENSRNOT00000098356
Ensembl Acc Id: ENSRNOP00000092807   ⟸   ENSRNOT00000111057
RefSeq Acc Id: NP_001381980   ⟸   NM_001395051
- Peptide Label: isoform 1
- UniProtKB: A0A8I6AIY8 (UniProtKB/TrEMBL),   A6ILX2 (UniProtKB/TrEMBL),   A0A0G2K8S8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q566D2-F1-model_v2 AlphaFold Q566D2 1-178 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693420
Promoter ID:EPDNEW_R3945
Type:initiation region
Name:Tigar_1
Description:TP53 induced glycolysis regulatory phosphatase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04159,654,056 - 159,654,116EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560038 AgrOrtholog
BioCyc Gene G2FUF-42949 BioCyc
BioCyc Pathway PWY66-423 [fructose 2,6-bisphosphate biosynthesis] BioCyc
BioCyc Pathway Image PWY66-423 BioCyc
Ensembl Genes ENSRNOG00000046064 Ensembl
  ENSRNOG00000051816 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000091662 ENTREZGENE
  ENSRNOT00000091662.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1240 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7319640 IMAGE-MGC_LOAD
InterPro His_Pase_superF_clade-1 UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/TrEMBL
  PG/BPGM_mutase_AS UniProtKB/TrEMBL
  Phosphoglycerate_Mutase UniProtKB/TrEMBL
KEGG Report rno:502894 UniProtKB/TrEMBL
MGC_CLONE MGC:105772 IMAGE-MGC_LOAD
NCBI Gene 502894 ENTREZGENE
PANTHER FRUCTOSE-2,6-BISPHOSPHATASE TIGAR UniProtKB/TrEMBL
  FRUCTOSE-2,6-BISPHOSPHATASE TIGAR UniProtKB/TrEMBL
Pfam His_Phos_1 UniProtKB/TrEMBL
PhenoGen Tigar PhenoGen
PROSITE PG_MUTASE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046064 RatGTEx
  ENSRNOG00000051816 RatGTEx
SMART PGAM UniProtKB/TrEMBL
Superfamily-SCOP SSF53254 UniProtKB/TrEMBL
UniProt A0A0G2K8S8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A442 ENTREZGENE
  A0A8I6AIY8 ENTREZGENE
  A6ILX2 ENTREZGENE, UniProtKB/TrEMBL
  Q566D2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-17 Tigar  TP53 induced glycolysis regulatory phosphatase  LOC502894  hypothetical protein LOC502894  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC502894  hypothetical protein LOC502894      Symbol and Name status set to provisional 70820 PROVISIONAL