Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rmdn2 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RMDN2 mRNA] | CTD | PMID:31150632 | Rmdn2 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Rmdn2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RMDN2 mRNA | CTD | PMID:36331819 | Rmdn2 | Rat | 1,2-dichloroethane | decreases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of RMDN2 mRNA | CTD | PMID:28960355 | Rmdn2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of RMDN2 mRNA | CTD | PMID:22206623 | Rmdn2 | Rat | 1-naphthyl isothiocyanate | decreases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in decreased expression of RMDN2 mRNA | CTD | PMID:25380136 | Rmdn2 | Rat | 17beta-estradiol | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of RMDN2 mRNA | CTD | PMID:19167446 | Rmdn2 | Rat | 17beta-estradiol | increases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Estradiol results in increased expression of RMDN2 mRNA | CTD | PMID:39298647 | Rmdn2 | Rat | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of RMDN2 mRNA | CTD | PMID:32145629 | Rmdn2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of RMDN2 mRNA | CTD | PMID:27291303 | Rmdn2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Rmdn2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of RMDN2 mRNA | CTD | PMID:16214954 | Rmdn2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RMDN2 mRNA | CTD | PMID:30096437 | Rmdn2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RMDN2 mRNA | CTD | PMID:26377647 | Rmdn2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RMDN2 mRNA | CTD | PMID:21215274|PMID:33387578 | Rmdn2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of RMDN2 mRNA] | CTD | PMID:21215274 | Rmdn2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RMDN2 mRNA | CTD | PMID:19770486 | Rmdn2 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RMDN2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Rmdn2 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in decreased expression of RMDN2 mRNA | CTD | PMID:25380136 | Rmdn2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of RMDN2 mRNA | CTD | PMID:39298647 | Rmdn2 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of RMDN2 mRNA | CTD | PMID:31881176 | Rmdn2 | Rat | aflatoxin B1 | decreases methylation | ISO | RMDN2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of RMDN2 gene | CTD | PMID:27153756 | Rmdn2 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | RMDN2 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of RMDN2 intron | CTD | PMID:30157460 | Rmdn2 | Rat | aflatoxin M1 | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of RMDN2 mRNA | CTD | PMID:30928695 | Rmdn2 | Rat | all-trans-retinoic acid | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RMDN2 mRNA | CTD | PMID:33167477 | Rmdn2 | Rat | antirheumatic drug | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of RMDN2 mRNA | CTD | PMID:24449571 | Rmdn2 | Rat | aristolochic acid A | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of RMDN2 mRNA | CTD | PMID:33212167 | Rmdn2 | Rat | arsenous acid | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of RMDN2 mRNA | CTD | PMID:26705709 | Rmdn2 | Rat | benzo[a]pyrene | increases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RMDN2 mRNA | CTD | PMID:19770486 | Rmdn2 | Rat | benzo[a]pyrene | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of RMDN2 mRNA | CTD | PMID:26238291 | Rmdn2 | Rat | bisphenol A | affects expression | ISO | RMDN2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of RMDN2 mRNA | CTD | PMID:20170705 | Rmdn2 | Rat | bisphenol A | decreases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of RMDN2 mRNA | CTD | PMID:33221593 | Rmdn2 | Rat | bisphenol A | increases methylation | ISO | RMDN2 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of RMDN2 gene | CTD | PMID:31601247 | Rmdn2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RMDN2 mRNA | CTD | PMID:32145629 | Rmdn2 | Rat | bisphenol A | multiple interactions | ISO | RMDN2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] affects the methylation of RMDN2 gene; [INS protein co-treated with more ... | CTD | PMID:28628672|PMID:31601247 | Rmdn2 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of RMDN2 gene | CTD | PMID:28505145 | Rmdn2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RMDN2 mRNA | CTD | PMID:25181051 | Rmdn2 | Rat | bisphenol A | increases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of RMDN2 mRNA | CTD | PMID:23798566 | Rmdn2 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of RMDN2 promoter | CTD | PMID:22457795 | Rmdn2 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of RMDN2 mRNA | CTD | PMID:25993096 | Rmdn2 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of RMDN2 mRNA | CTD | PMID:33453195 | Rmdn2 | Rat | carbon nanotube | decreases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of RMDN2 mRNA | CTD | PMID:25554681|PMID:25620056 | Rmdn2 | Rat | CGP 52608 | multiple interactions | ISO | RMDN2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RMDN2 gene] | CTD | PMID:28238834 | Rmdn2 | Rat | chlordecone | increases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Chlordecone results in increased expression of RMDN2 mRNA | CTD | PMID:29980752 | Rmdn2 | Rat | chlorpyrifos | decreases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of RMDN2 mRNA | CTD | PMID:37019170 | Rmdn2 | Rat | chromium(6+) | affects expression | ISO | Rmdn2 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of RMDN2 mRNA | CTD | PMID:28472532 | Rmdn2 | Rat | copper(II) sulfate | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of RMDN2 mRNA | CTD | PMID:19549813 | Rmdn2 | Rat | coumestrol | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of RMDN2 mRNA | CTD | PMID:19167446 | Rmdn2 | Rat | coumestrol | multiple interactions | ISO | RMDN2 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RMDN2 mRNA | CTD | PMID:19167446 | Rmdn2 | Rat | cyclosporin A | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of RMDN2 mRNA | CTD | PMID:25562108 | Rmdn2 | Rat | decabromodiphenyl ether | decreases expression | EXP | | 6480464 | decabromobiphenyl ether results in decreased expression of RMDN2 mRNA | CTD | PMID:23640034 | Rmdn2 | Rat | dexamethasone | multiple interactions | ISO | RMDN2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Rmdn2 | Rat | diarsenic trioxide | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of RMDN2 mRNA | CTD | PMID:26705709 | Rmdn2 | Rat | dioxygen | multiple interactions | ISO | Rmdn2 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of RMDN2 mRNA | CTD | PMID:30529165 | Rmdn2 | Rat | disodium selenite | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of RMDN2 mRNA | CTD | PMID:18175754 | Rmdn2 | Rat | Enterolactone | multiple interactions | ISO | RMDN2 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of RMDN2 mRNA | CTD | PMID:19167446 | Rmdn2 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of RMDN2 mRNA | CTD | PMID:24136188 | Rmdn2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of RMDN2 mRNA | CTD | PMID:24136188 | Rmdn2 | Rat | flutamide | decreases expression | EXP | | 6480464 | Flutamide results in decreased expression of RMDN2 mRNA | CTD | PMID:24793618 | Rmdn2 | Rat | FR900359 | decreases phosphorylation | ISO | RMDN2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of RMDN2 protein | CTD | PMID:37730182 | Rmdn2 | Rat | fulvestrant | multiple interactions | ISO | RMDN2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] affects the methylation of RMDN2 gene | CTD | PMID:31601247 | Rmdn2 | Rat | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of RMDN2 mRNA | CTD | PMID:26194646 | Rmdn2 | Rat | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of RMDN2 mRNA | CTD | PMID:24136188 | Rmdn2 | Rat | hydrogen peroxide | affects expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of RMDN2 mRNA | CTD | PMID:20044591 | Rmdn2 | Rat | indometacin | multiple interactions | ISO | RMDN2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... | CTD | PMID:28628672 | Rmdn2 | Rat | lead(0) | increases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Lead results in increased expression of RMDN2 mRNA | CTD | PMID:19921347 | Rmdn2 | Rat | levofloxacin | decreases expression | EXP | | 6480464 | Levofloxacin results in decreased expression of RMDN2 mRNA | CTD | PMID:24136188 | Rmdn2 | Rat | N-methyl-4-phenylpyridinium | decreases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of RMDN2 mRNA | CTD | PMID:28801915 | Rmdn2 | Rat | N-nitrosodimethylamine | decreases expression | EXP | | 6480464 | Dimethylnitrosamine results in decreased expression of RMDN2 mRNA | CTD | PMID:25380136 | Rmdn2 | Rat | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of RMDN2 mRNA | CTD | PMID:24136188 | Rmdn2 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of RMDN2 mRNA | CTD | PMID:22110744 | Rmdn2 | Rat | nimesulide | decreases expression | EXP | | 6480464 | nimesulide results in decreased expression of RMDN2 mRNA | CTD | PMID:24136188 | Rmdn2 | Rat | orphenadrine | affects expression | EXP | | 6480464 | Orphenadrine affects the expression of RMDN2 mRNA | CTD | PMID:23665939 | Rmdn2 | Rat | paracetamol | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of RMDN2 mRNA | CTD | PMID:29067470 | Rmdn2 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of RMDN2 mRNA | CTD | PMID:32680482 | Rmdn2 | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | RMDN2 (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of RMDN2 mRNA | CTD | PMID:27153767 | Rmdn2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Rmdn2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RMDN2 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Rmdn2 | Rat | pirinixic acid | decreases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of RMDN2 mRNA | CTD | PMID:23811191 | Rmdn2 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of RMDN2 mRNA | CTD | PMID:28374803 | Rmdn2 | Rat | silicon dioxide | increases expression | EXP | | 6480464 | Silicon Dioxide results in increased expression of RMDN2 mRNA | CTD | PMID:22431001 | Rmdn2 | Rat | sodium dichromate | decreases expression | EXP | | 6480464 | sodium bichromate results in decreased expression of RMDN2 mRNA | CTD | PMID:25993096 | Rmdn2 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of RMDN2 mRNA] | CTD | PMID:31150632 | Rmdn2 | Rat | tetrachloromethane | decreases expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of RMDN2 mRNA | CTD | PMID:31919559 | Rmdn2 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of RMDN2 mRNA | CTD | PMID:31150632 | Rmdn2 | Rat | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of RMDN2 mRNA | CTD | PMID:30012374 | Rmdn2 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of RMDN2 mRNA | CTD | PMID:33387578 | Rmdn2 | Rat | triphenyl phosphate | decreases expression | EXP | | 6480464 | triphenyl phosphate results in decreased expression of RMDN2 mRNA | CTD | PMID:30589522 | Rmdn2 | Rat | trovafloxacin | decreases expression | EXP | | 6480464 | trovafloxacin results in decreased expression of RMDN2 mRNA | CTD | PMID:24136188 | Rmdn2 | Rat | valdecoxib | decreases expression | EXP | | 6480464 | valdecoxib results in decreased expression of RMDN2 mRNA | CTD | PMID:24136188 | Rmdn2 | Rat | valproic acid | affects expression | ISO | Rmdn2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of RMDN2 mRNA | CTD | PMID:17292431 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















