Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Akap3 | Rat | spermatogenic failure 82 | | ISO | AKAP3 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Akap3 | Rat | spermatogenic failure 82 | | ISO | AKAP3 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum. | Brown PR, etal., Biol Reprod 2003 Jun;68(6):2241-8. Epub 2003 Jan 22. |
| 2. | A-kinase anchoring proteins: from protein complexes to physiology and disease. | Carnegie GK, etal., IUBMB Life. 2009 Apr;61(4):394-406. |
| 3. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 4. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
| 5. | GOA pipeline | RGD automated data pipeline |
| 6. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 7. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| 8. | Comprehensive gene review and curation | RGD comprehensive gene curation |
| 9. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
| 10. | Localized effects of cAMP mediated by distinct routes of protein kinase A. | Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67. |
| PMID:10319321 | PMID:11278869 | PMID:15257753 | PMID:16687649 | PMID:21630459 | PMID:27869233 | PMID:30745215 |
| Akap3 (Rattus norvegicus - Norway rat) |
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| AKAP3 (Homo sapiens - human) |
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| Akap3 (Mus musculus - house mouse) |
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| Akap3 (Chinchilla lanigera - long-tailed chinchilla) |
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| AKAP3 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| AKAP3 (Canis lupus familiaris - dog) |
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| Akap3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| AKAP3 (Sus scrofa - pig) |
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| AKAP3 (Chlorocebus sabaeus - green monkey) |
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| Akap3 (Heterocephalus glaber - naked mole-rat) |
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| Akap3 (Rattus rattus - black rat) |
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Variants in Akap3
71 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| AI577267 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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| 12 | 10 | 58 | 145 | 84 | 83 | 52 | 45 | 52 | 4 | 271 | 132 | 8 | 126 | 68 | 90 | 31 | 15 | 15 |
| RefSeq Transcripts | NM_001005557 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| XM_006237488 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006237489 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006237491 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_006237492 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008763288 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008763289 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_008763290 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017592653 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_017592654 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039107683 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_039107684 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063286142 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063286143 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063286144 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063286145 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063286146 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| XM_063286147 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | BC081924 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| CH473964 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| JAXUCZ010000004 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| Ensembl Acc Id: | ENSRNOT00000079225 ⟹ ENSRNOP00000071639 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000086525 ⟹ ENSRNOP00000072217 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| RefSeq Acc Id: | NM_001005557 ⟹ NP_001005557 | ||||||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_006237488 ⟹ XP_006237550 | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_006237489 ⟹ XP_006237551 | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_006237492 ⟹ XP_006237554 | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_008763289 ⟹ XP_008761511 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_008763290 ⟹ XP_008761512 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_017592653 ⟹ XP_017448142 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_017592654 ⟹ XP_017448143 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_039107683 ⟹ XP_038963611 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039107684 ⟹ XP_038963612 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063286142 ⟹ XP_063142212 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063286143 ⟹ XP_063142213 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063286144 ⟹ XP_063142214 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063286145 ⟹ XP_063142215 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063286146 ⟹ XP_063142216 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063286147 ⟹ XP_063142217 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Protein RefSeqs | NP_001005557 | (Get FASTA) | NCBI Sequence Viewer |
| XP_006237550 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006237551 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_006237554 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008761511 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_008761512 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017448142 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_017448143 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038963611 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_038963612 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063142212 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063142213 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063142214 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063142215 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063142216 | (Get FASTA) | NCBI Sequence Viewer | |
| XP_063142217 | (Get FASTA) | NCBI Sequence Viewer | |
| GenBank Protein | AAH81924 | (Get FASTA) | NCBI Sequence Viewer |
| EDM01825 | (Get FASTA) | NCBI Sequence Viewer | |
| Ensembl Protein | ENSRNOP00000072217 | ||
| ENSRNOP00000072217.2 |
| RefSeq Acc Id: | NP_001005557 ⟸ NM_001005557 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_006237554 ⟸ XM_006237492 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_006237550 ⟸ XM_006237488 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_006237551 ⟸ XM_006237489 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_008761512 ⟸ XM_008763290 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_008761511 ⟸ XM_008763289 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_017448143 ⟸ XM_017592654 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_017448142 ⟸ XM_017592653 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000071639 ⟸ ENSRNOT00000079225 |
| Ensembl Acc Id: | ENSRNOP00000072217 ⟸ ENSRNOT00000086525 |
| RefSeq Acc Id: | XP_038963612 ⟸ XM_039107684 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_038963611 ⟸ XM_039107683 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | Q66HC6 (UniProtKB/TrEMBL), A0A0G2K2E9 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063142214 ⟸ XM_063286144 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K2E9 (UniProtKB/TrEMBL), Q66HC6 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063142217 ⟸ XM_063286147 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K2E9 (UniProtKB/TrEMBL), Q66HC6 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063142215 ⟸ XM_063286145 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K2E9 (UniProtKB/TrEMBL), Q66HC6 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063142213 ⟸ XM_063286143 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K2E9 (UniProtKB/TrEMBL), Q66HC6 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063142216 ⟸ XM_063286146 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K2E9 (UniProtKB/TrEMBL), Q66HC6 (UniProtKB/TrEMBL) |
| RefSeq Acc Id: | XP_063142212 ⟸ XM_063286142 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | A0A0G2K2E9 (UniProtKB/TrEMBL), Q66HC6 (UniProtKB/TrEMBL) |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-Q66HC6-F1-model_v2 | AlphaFold | Q66HC6 | 1-858 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| RGD ID: | 13693417 | ||||||||
| Promoter ID: | EPDNEW_R3942 | ||||||||
| Type: | initiation region | ||||||||
| Name: | Akap3_1 | ||||||||
| Description: | A-kinase anchoring protein 3 | ||||||||
| SO ACC ID: | SO:0000170 | ||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
| Experiment Methods: | Single-end sequencing. | ||||||||
| Position: |
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| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1359735 | AgrOrtholog |
| BioCyc Gene | G2FUF-42960 | BioCyc |
| Ensembl Genes | ENSRNOG00000059227 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000086525 | ENTREZGENE |
| ENSRNOT00000086525.3 | UniProtKB/TrEMBL | |
| IMAGE_CLONE | IMAGE:7112940 | IMAGE-MGC_LOAD |
| InterPro | AKAP_110 | UniProtKB/TrEMBL |
| AKAP_110_C | UniProtKB/TrEMBL | |
| SPHK1-interactor_AKAP_110 | UniProtKB/TrEMBL | |
| KEGG Report | rno:312720 | UniProtKB/TrEMBL |
| MGC_CLONE | MGC:93915 | IMAGE-MGC_LOAD |
| NCBI Gene | 312720 | ENTREZGENE |
| PANTHER | A-KINASE ANCHOR PROTEIN 3 | UniProtKB/TrEMBL |
| AKAP_110 | UniProtKB/TrEMBL | |
| Pfam | AKAP_110 | UniProtKB/TrEMBL |
| PhenoGen | Akap3 | PhenoGen |
| RatGTEx | ENSRNOG00000059227 | RatGTEx |
| SMART | AKAP_110 | UniProtKB/TrEMBL |
| UniProt | A0A0G2K2E9 | ENTREZGENE, UniProtKB/TrEMBL |
| Q66HC6 | ENTREZGENE, UniProtKB/TrEMBL |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2015-11-25 | Akap3 | A-kinase anchoring protein 3 | Akap3 | A kinase (PRKA) anchor protein 3 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2006-03-30 | Akap3 | A kinase (PRKA) anchor protein 3 | A-kinase anchor protein 3 | Name updated | 1299863 | APPROVED | |
| 2005-07-29 | Akap3 | A-kinase anchor protein 3 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |