Btrc Rat Gene (beta-transducin repeat containing)

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Keyword

Gene:
Btrc ( Rattus norvegicus )
beta-transducin repeat containing
Description: E3 ligase that activates NF-kappaB by increasing the rate of IkappaBalpha degradation
Synonyms: MGC105884; beta-TrCP1;  (details...)
ArrayIDs: 6704032; 6083046; 6606794; 6721785; 6328019; 5970454; 6389035; A_44_P336626; 6126876; 6026232; A_43_P18668; 1374654_at; 5667767; 6183588; 5865822; 6539449; rc_AI179552_at; 6688833; 6279545; 6200829; 6271033; 5834163; 6644206; 6162424; GE17567; 6582236; 5887037; 5797820;  (details...)
Gene Type: protein-coding

Additional Data

Homologs

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Btrc Rat Celera Assembly 1 240018532 - 240184606
RGSC genome assembly v3.4 1 250529174 - 250693952
Cytogenetic 1 q54
genome assembly 3.1 1 250789742 - 250954519

View comparative maps:      NCBI MapViewer

Genome
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Browsers:

Annotation
Molecular Function

Gene Ontology

protein binding (details...)
Pathway

Ontology

canonical Wnt signaling pathway (details...)

External Links
Databases
DATABASE ID SOURCE
SMART: WD40 IPI
SMART: FBOX IPI
PROSITE: FBOX IPI
PROSITE: WD_REPEATS_1 IPI
PROSITE: WD_REPEATS_REGION IPI
PROSITE: WD_REPEATS_2 IPI
UNIPARC: UPI00015FF97B IPI
UNIPARC: UPI00004525C6 IPI
KEGG Report: rno:361765 ENTREZGENE
HomoloGene Group ID: 39330 ENTREZGENE
Pfam: WD40 IPI
Pfam: F-box IPI
KEGG Pathway: 04340 ENTREZGENE
KEGG Pathway: 04310 ENTREZGENE
KEGG Pathway: 04120 ENTREZGENE
InterPro: F-box. IPI
InterPro: G-protein_beta_WD-40_rep_reg. IPI
InterPro: WD40/YVTN_repeat-like_dom. IPI
InterPro: WD40_repeat. IPI
InterPro: WD40_repeat-like_dom. IPI
InterPro: WD40_repeat_CS. IPI
InterPro: WD40_repeat_dom. IPI
InterPro: WD40_repeat_sg. IPI
InterPro: WD40_repeat_2. IPI
Ensembl Protein: ENSRNOP00000022426 IPI
Ensembl Protein: ENSRNOP00000062209 IPI
IPI: IPI00372531 IPI
IPI: IPI00951294 IPI
Gene3D-CATH: WD40/YVTN_repeat-like IPI
Entrez Gene: Btrc ENTREZGENE
IMAGE_CLONE: IMAGE:7131883 IMAGE-MGC_LOAD
MGC_CLONE: MGC:105884 IMAGE-MGC_LOAD
UniProt: Q5U4E5_RAT IPI
Ensembl Genes: ENSRNOG00000016280 IPI
Superfamily-SCOP: WD40_like IPI
PRINTS: GPROTEINBRPT. IPI
Sequences
Nucleotide: CH473986 Get FASTA Search GEO Profiles
Nucleotide: BC085125 Get FASTA Search GEO Profiles
Nucleotide: EV771066 Get FASTA Search GEO Profiles
Nucleotide: CB584165 Get FASTA Search GEO Profiles
Nucleotide: NM_001007148 Get FASTA Search GEO Profiles
(View all 5 Nucleotide Accessions)
Protein: NP_001007149 Get FASTA
Protein: EDL94307 Get FASTA
Protein: Q5U4E5 Get FASTA
Protein: AAH85125 Get FASTA
(View all 4 Protein Accessions)
Clusters
UniGene: 21800

References
Curated References
5 references in RGD related to Btrc

Other References
2 other references at PubMed related to Btrc

Database Information
RGD ID 1359721
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

30-MAR-06: Btrc beta-transducin repeat containing APPROVED Symbol and Name status set to approved 1299863

29-JUL-05: Btrc beta-transducin repeat containing PROVISIONAL Symbol and Name status set to provisional 70820