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Gene: Ift74 (intraflagellar transport 74) Rattus norvegicus

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Symbol:

Ift74

Name:

intraflagellar transport 74

RGD ID:

1359704

Description:

Predicted to enable beta-tubulin binding activity and chromatin binding activity. Predicted to be involved in intraciliary transport involved in cilium assembly. Predicted to act upstream of or within several processes, including keratinocyte development; negative regulation of keratinocyte proliferation; and non-motile cilium assembly. Predicted to be located in centrosome and nucleus. Predicted to be part of intraciliary transport particle A and intraciliary transport particle B. Predicted to be active in cilium. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 22; Joubert syndrome; and spermatogenic failure 58. Orthologous to human IFT74 (intraflagellar transport 74); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amitrole; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Ccdc2; coiled-coil domain containing 2; intraflagellar transport 74 homolog; intraflagellar transport 74 homolog (Chlamydomonas); intraflagellar transport protein 74 homolog; MGC94371

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	IFT74 (intraflagellar transport 74)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ift74 (intraflagellar transport 74)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ift74 (intraflagellar transport 74)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	IFT74 (intraflagellar transport 74)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	IFT74 (intraflagellar transport 74)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ift74 (intraflagellar transport 74)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	IFT74 (intraflagellar transport 74)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	IFT74 (intraflagellar transport 74)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ift74 (intraflagellar transport 74)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	IFT74 (intraflagellar transport 74)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ift74 (intraflagellar transport 74)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ift74 (intraflagellar transport 74)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ift-74	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ift-74	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ift74	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ift74	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	114,576,106 - 114,679,581 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	114,593,397 - 114,679,581 (+)	Ensembl				GRCr8
mRatBN7.2	5	109,460,372 - 109,563,839 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	109,474,255 - 109,563,833 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	112,052,931 - 112,142,409 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	113,778,717 - 113,868,197 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	113,840,948 - 113,930,430 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	5	114,531,068 - 114,620,613 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	5	116,377,590 - 116,467,138 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	5	115,552,900 - 115,642,445 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	5	109,253,376 - 109,342,921 (+)	NCBI		F344_StmMcwi
Rnor_6.0	5	113,579,065 - 113,682,485 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	113,592,919 - 113,682,484 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	117,523,747 - 117,629,816 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	114,913,347 - 115,003,963 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	108,101,293 - 108,191,093 (+)	NCBI		Celera
RGSC_v3.1	5	114,918,572 - 115,009,188 (+)	NCBI
Cytogenetic Map	5	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asphyxiating thoracic dystrophy (ISO)

autism spectrum disorder (ISO)

Bardet-Biedl syndrome (ISO)

Bardet-Biedl syndrome 22 (ISO)

fundus dystrophy (ISO)

genetic disease (ISO)

Joubert Syndrome 40 (ISO)

microcephaly (ISO)

optic atrophy (ISO)

retinitis pigmentosa 1 (ISO)

short-rib thoracic dysplasia 6 with or without polydactyly (ISO)

spermatogenic failure 58 (ISO)

visceral heterotaxy (ISS)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

asbestos (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

diuron (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

enzalutamide (ISO)

epoxiconazole (ISO)

formaldehyde (ISO)

indole-3-methanol (EXP)

indometacin (ISO)

isoprenaline (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (EXP)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

SB 431542 (ISO)

selenium atom (ISO)

sodium dichromate (EXP)

succimer (ISO)

sunitinib (ISO)

temozolomide (ISO)

thalidomide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cilium assembly (IEA,ISO)

determination of left/right symmetry (ISO)

epidermis development (ISO)

heart development (ISO)

intraciliary transport (IEA)

intraciliary transport involved in cilium assembly (IBA,IEA,ISO)

keratinocyte development (ISO)

negative regulation of epithelial cell proliferation (ISO)

non-motile cilium assembly (ISO)

Notch signaling pathway (ISO)

positive regulation of cell adhesion mediated by integrin (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

Cellular Component

centriolar satellite (IEA,ISO)

centrosome (IEA,ISO)

ciliary basal body (IEA,ISO)

cilium (IBA,IEA,ISO)

Golgi apparatus (IEA,ISO)

intraciliary transport particle A (IEA,ISO)

intraciliary transport particle B (IBA,IEA,ISO)

nucleus (IEA,ISO)

Molecular Function

beta-tubulin binding (IBA,IEA,ISO)

chromatin binding (IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling.	Bell SE, etal., J Cell Sci 2001 Aug;114(Pt 15):2755-73.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:16705683	PMID:19253336	PMID:20545763	PMID:21703454	PMID:23810713	PMID:23990561	PMID:24596149	PMID:25443296	PMID:25807483

Genomics

Comparative Map Data

Ift74
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	114,576,106 - 114,679,581 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	114,593,397 - 114,679,581 (+)	Ensembl				GRCr8
mRatBN7.2	5	109,460,372 - 109,563,839 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	109,474,255 - 109,563,833 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	112,052,931 - 112,142,409 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	113,778,717 - 113,868,197 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	113,840,948 - 113,930,430 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	5	114,531,068 - 114,620,613 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	5	116,377,590 - 116,467,138 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	5	115,552,900 - 115,642,445 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	5	109,253,376 - 109,342,921 (+)	NCBI		F344_StmMcwi
Rnor_6.0	5	113,579,065 - 113,682,485 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	113,592,919 - 113,682,484 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	117,523,747 - 117,629,816 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	114,913,347 - 115,003,963 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	108,101,293 - 108,191,093 (+)	NCBI		Celera
RGSC_v3.1	5	114,918,572 - 115,009,188 (+)	NCBI
Cytogenetic Map	5	q33	NCBI

IFT74
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	26,947,110 - 27,066,134 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	26,947,039 - 27,066,134 (+)	Ensembl			hg38	GRCh38
GRCh37	9	26,947,108 - 27,066,132 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	26,937,037 - 27,052,931 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	9	26,946,409 - 27,052,802	NCBI
Celera	9	26,875,190 - 26,991,082 (+)	NCBI		Celera
Cytogenetic Map	9	p21.2	NCBI
HuRef	9	26,899,912 - 27,015,729 (+)	NCBI		HuRef
CHM1_1	9	26,946,816 - 27,062,719 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	9	26,957,713 - 27,076,715 (+)	NCBI		T2T-CHM13v2.0

Ift74
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	94,491,503 - 94,581,470 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	94,502,728 - 94,581,466 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	94,603,266 - 94,693,233 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	94,614,491 - 94,693,229 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	94,281,211 - 94,359,924 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	94,146,847 - 94,185,247 (+)	NCBI		MGSCv36	mm8
Celera	4	93,023,677 - 93,103,044 (+)	NCBI		Celera
Cytogenetic Map	4	C5	NCBI
cM Map	4	43.34	NCBI

Ift74
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	7,775,981 - 7,872,423 (-)	Ensembl
ChiLan1.0	NW_004955472	7,779,705 - 7,872,423 (-)	NCBI	ChiLan1.0	ChiLan1.0

IFT74
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	97,482,355 - 97,588,966 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	97,485,095 - 97,597,750 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	26,802,459 - 26,912,292 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	27,409,962 - 27,514,756 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	27,415,565 - 27,514,558 (+)	Ensembl			panPan2	panpan1.1

IFT74
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	45,159,124 - 45,242,019 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	45,161,086 - 45,242,012 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	43,834,528 - 43,919,561 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	46,103,920 - 46,188,986 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	46,105,889 - 46,188,982 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	44,761,014 - 44,845,589 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	44,650,812 - 44,735,508 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	45,397,519 - 45,482,097 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Ift74
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	160,007,880 - 160,079,709 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936611	2,588,695 - 2,660,532 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936611	2,588,711 - 2,660,496 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IFT74
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	196,086,072 - 196,173,880 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	196,084,498 - 196,173,880 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	218,533,803 - 218,621,870 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IFT74
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	12	52,983,050 - 53,103,525 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM

Ift74
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	31,188,987 - 31,306,815 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624736	31,188,963 - 31,308,872 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Ift74
856 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	129
Count of miRNA genes:	105
Interacting mature miRNAs:	109
Transcripts:	ENSRNOT00000011336
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357396	Bw44	Body weight QTL 44	4.19		body mass (VT:0001259)	body weight (CMO:0000012)	5	73779642	118779642	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	102105698	152749382	Rat
2303586	Gluco52	Glucose level QTL 52	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	100826632	145826632	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	44924861	153890773	Rat
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	38207390	136631402	Rat
1298070	Scl18	Serum cholesterol level QTL 18	3.7		blood LDL cholesterol amount (VT:0000181)	calculated plasma low density lipoprotein cholesterol level (CMO:0001245)	5	84630798	129630798	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	99905133	172190305	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	48523123	134369373	Rat
2302381	Bw84	Body weight QTL 84	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
1357402	Bw46	Body weight QTL 46	4.47		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	5	73779642	118779642	Rat
1298077	Bp157	Blood pressure QTL 157			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	114474223	121056531	Rat
7411582	Foco3	Food consumption QTL 3	7.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	65089051	166764498	Rat
1598859	Cm66	Cardiac mass QTL 66	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	84630798	129630798	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	112142946	157142946	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	112142946	157142946	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	110770739	155770739	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	51657967	166600247	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	112142946	157142946	Rat
1582212	Livw2	Liver weight QTL 2	3.5	0.0004	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	5	104018576	124314782	Rat
7411564	Bw135	Body weight QTL 135		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	92583776	137583776	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	98972960	143972960	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55124766	172190305	Rat
7411601	Foco12	Food consumption QTL 12	19.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	92583776	137583776	Rat
2303618	Vencon1	Ventilatory control QTL 1	3.8		respiration trait (VT:0001943)	oxygen consumption (CMO:0002169)	5	100826632	145826632	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	111236572	156236572	Rat
7394708	Emca11	Estrogen-induced mammary cancer QTL 11			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	73176602	118176602	Rat
1598846	Bp293	Blood pressure QTL 293	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	84630798	129630798	Rat
7394710	Emca12	Estrogen-induced mammary cancer QTL 12			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	94034903	139034903	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	114131300	159131300	Rat
1358909	Kidm25	Kidney mass QTL 25	1.87		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	95062526	133270832	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	60601597	137492949	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	112142946	157142946	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	112142946	157142946	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	36460764	136631402	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	74335621	156302135	Rat
1600362	Mcs19	Mammary carcinoma susceptibility QTL 19	2.5		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	82032155	127032155	Rat
1298086	Bp156	Blood pressure QTL 156			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	89369373	134369373	Rat
2290005	Mcs24	Mammary carcinoma susceptibility QTL 24			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	69835120	114835120	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	70969494	136328156	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	114131300	159131300	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	97492524	133270832	Rat
2312671	Scl64	Serum cholesterol level QTL 64		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	73779642	118779642	Rat
6903316	Bw113	Body weight QTL 113	2	0.0103	body mass (VT:0001259)	body weight (CMO:0000012)	5	92881678	137881678	Rat
1358889	Bp261	Blood pressure QTL 261	2.86		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	95062526	133270832	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	104262817	153890625	Rat

Markers in Region

RH128708

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	109,563,602 - 109,563,801 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	113,682,249 - 113,682,447	NCBI	Rnor6.0
Rnor_5.0	5	117,629,580 - 117,629,778	UniSTS	Rnor5.0
RGSC_v3.4	5	115,003,727 - 115,003,925	UniSTS	RGSC3.4
Celera	5	108,190,857 - 108,191,055	UniSTS
RH 3.4 Map	5	780.5	UniSTS
Cytogenetic Map	5	q33	UniSTS

AI232423

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	109,497,180 - 109,497,290 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	113,615,820 - 113,615,929	NCBI	Rnor6.0
Rnor_5.0	5	117,565,249 - 117,565,358	UniSTS	Rnor5.0
RGSC_v3.4	5	114,937,310 - 114,937,419	UniSTS	RGSC3.4
Celera	5	108,124,371 - 108,124,480	UniSTS
RH 3.4 Map	5	780.5	UniSTS
Cytogenetic Map	5	q33	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001007001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017593367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039109896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063287637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC133043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083611	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000011336 ⟹ ENSRNOP00000011336

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	114,593,397 - 114,679,581 (+)	Ensembl
mRatBN7.2 Ensembl	5	109,474,255 - 109,563,833 (+)	Ensembl
Rnor_6.0 Ensembl	5	113,592,919 - 113,682,484 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099310 ⟹ ENSRNOP00000097814

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	114,593,397 - 114,654,242 (+)	Ensembl
mRatBN7.2 Ensembl	5	109,474,255 - 109,538,505 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000172970 ⟹ ENSRNOP00000111300

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	114,593,397 - 114,679,581 (+)	Ensembl

RefSeq Acc Id:

NM_001007001 ⟹ NP_001007002

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	114,590,014 - 114,679,581 (+)	NCBI
mRatBN7.2	5	109,474,280 - 109,563,839 (+)	NCBI
Dahl_SR_JrHsd	5	114,531,068 - 114,620,613 (+)	NCBI
Lyon_Normotensive	5	116,377,590 - 116,467,138 (+)	NCBI
Lyon_Hypertensive	5	115,552,900 - 115,642,445 (+)	NCBI
F344_StmMcwi	5	109,253,376 - 109,342,921 (+)	NCBI
Rnor_6.0	5	113,592,919 - 113,682,485 (+)	NCBI
Rnor_5.0	5	117,523,747 - 117,629,816 (+)	NCBI
RGSC_v3.4	5	114,913,347 - 115,003,963 (+)	RGD
Celera	5	108,101,293 - 108,191,093 (+)	RGD

Sequence:

show sequence

CTGAGGCCTGGCGCCCTGGCTGTGCTCTGGTGTGTGGTGAGACCGGAACTGACTCTCGGTTAGG
CTCCTCAGAAAGAAGTTCCTGTCGTAGAGTCCTAGTGGCGTCCCATTCGCACCAAGCAAGTGGT
TGAAGTGAACAATGGCCAGTAATCACAAATCTGCAGCACCTCGCCCTATTTCTCGGGGTGGAAT
AGGACTAACAGGAAGGCCTCCTTCTGGAATAAGACCCCCATCTGGGACTGTTCGAGTGGCCACT
GCAATGCCACCAGCAACAGCAAGACCAGGTTCCCGTGGTGGTCCCCTAGGGACTGGCGGAGTTT
TGTCATCTCAAATCAAAGTTGCTGATCGTCCTGTAACCCAGCAAGGTTTGAGTGGAATGAAGAC
TGGCATGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTACTATCTTGGACTTCTTAGGAGC
AAAATAAGTGAACTTACAACTGAAATTAATAAACTTCAGAAAGAGATAGAAATGTACAACCAAG
AAAATTCAGTATATTTGTCATATGAAAAGAGGGCAGAGACATTAGCTGTGGAAATTAAAGACTT
TCAAGGACAACTAGCAGACTACAATATGTTGGTAGATAAACTTAATACCAATACCGAAATGGAA
GAAGTAATGAATGATTACAACATGCTTAAAGCTCAAAATGATCGAGAAACACAAAGTATGGATG
TCATATTTACCGAAAGACAAGCGAAAGAAAAACAAATCAGAAGTGTAGAAGAAGAAGTTGAACA
AGAAAAGCAGGCAGCAGATGGCATTATCAAAAATATGTCTCCTGAAAAACAAGTCAAGTACATA
GAAATGAAAACCACGAATGAGAAACTATTGCAGGAATTAGATACACTTCAGCAACAACTAGATT
CACTGAACATTAAAAAGGAGAGCCTAGAAACTGAAATAGCACACTCCCAGGTAAAACAAGAGGC
TGTATTGCTATATGAAAAACTTTATGAGTTAGAGTCCCATCGAGATCAAATGATTGCAGAAGAC
AAAAGCATGGGATCGCCAATGGAGGAAAGGGAGAGATTGCTTAAGCAGGTTAAAGAAGATAATC
AGGAAATAGCCAGCATGGAGAGACAGTTAACAGATATAAAGGAAAAAATAAATCAGTTTAGTGA
AGAGATTAGACAACTTGACATGGATTTAGAGGAACACCAAGGTGAAATGAATCAAAAATACAAG
GAGCTTAAAAAAAGGGAAGAAAATATGGATGCTTTTATAGAGACTTTTGAGGAAACGAAGAATC
AGGAACTAGAGCGGAAGGCACAGATAGAAACCAGCATCATCACACTCTTAGAGCATTGCAGTCG
GAATATAAATCGTATGAAACAGATATCCTCCATCACCAACCAAGAGCTAAAGATGATGCAGGAT
GACCTCAGTTTTAAATCAACTGAAATGCAGAAGTCACAGACAACAGCTAGGAATTTGACCTCAG
ACAGTCAGCGTCTACAGCTGGATCTCCAGAAAATGGAACTTTTGGAAAGTAAGATGACAGAAGA
GCAACAGTCTCTGAAAAACAAAATCAAGCAAATGACTGCTGACCTGGAGACATACAGTGACCTG
GCAGCTTTAAAATCATCAGCTGAAGAGAAGAAGAAGAAATTACATCAAGAAAGAACAGTATTGT
CAACCCACAGAAATGCCTTTAAGAAAATAATGGAGAAGCTGACTACAGATTATGAGGCACTGAA
AACACAACTTCAAGACAATGAGACACATGCTCAGCTTACAAACTTGGAGAGGAAGTGGCAGCAT
CTGGAGCAAAATAATTTTGTAATGAAAGAGTTCATAGCAACCAAGAGTCAGGAGAGTGATTACC
AGCCAGTGATTAAAAATGTGATGAAGCAGATTGCAGAGTACAATAAAACCATCATGGATGCTCT
CCATAGTGCCAGCAGAAGCTGAAACGAAGTCCACTGAATCTACAAGAATCCACAAGCATGCTAA
AAGTAAATTAGCTTCCTCTTGAAGAGTTAGACCCCAGGTTTTTAAATGCCATGGTTTTGTGATC
TCCTTGACGGAGAGATATCTTGCATAGTTAAATAATTCAATAAATGTTTGCATATAACTCAAAA
AAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017593367 ⟹ XP_017448856

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	114,576,106 - 114,679,581 (+)	NCBI
mRatBN7.2	5	109,460,372 - 109,563,836 (+)	NCBI
Rnor_6.0	5	113,579,065 - 113,682,485 (+)	NCBI

Sequence:

show sequence

TGTGCGTCGGGCTGCAAGGCAACGCGGACCGAAACTTTCTCCCCTTCTGCGCCCTGGATCGCGG
GACGAAGAAGGGACGTGGTTGAAGTGAACAATGGCCAGTAATCACAAATCTGCAGCACCTCGCC
CTATTTCTCGGGGTGGAATAGGACTAACAGGAAGGCCTCCTTCTGGAATAAGACCCCCATCTGG
GACTGTTCGAGTGGCCACTGCAATGCCACCAGCAACAGCAAGACCAGGTTCCCGTGGTGGTCCC
CTAGGGACTGGCGGAGTTTTGTCATCTCAAATCAAAGTTGCTGATCGTCCTGTAACCCAGCAAG
GTTTGAGTGGAATGAAGACTGGCATGAAAGGTCCCCAGAGGCAAATTTTAGACAAATCTTACTA
TCTTGGACTTCTTAGGAGCAAAATAAGTGAACTTACAACTGAAATTAATAAACTTCAGAAAGAG
ATAGAAATGTACAACCAAGAAAATTCAGTATATTTGTCATATGAAAAGAGGGCAGAGACATTAG
CTGTGGAAATTAAAGACTTTCAAGGACAACTAGCAGACTACAATATGTTGGTAGATAAACTTAA
TACCAATACCGAAATGGAAGAAGTAATGAATGATTACAACATGCTTAAAGCTCAAAATGATCGA
GAAACACAAAGTATGGATGTCATATTTACCGAAAGACAAGCGAAAGAAAAACAAATCAGAAGTG
TAGAAGAAGAAGTTGAACAAGAAAAGCAGGCAGCAGATGGCATTATCAAAAATATGTCTCCTGA
AAAACAAGTCAAGTACATAGAAATGAAAACCACGAATGAGAAACTATTGCAGGAATTAGATACA
CTTCAGCAACAACTAGATTCACTGAACATTAAAAAGGAGAGCCTAGAAACTGAAATAGCACACT
CCCAGGTAAAACAAGAGGCTGTATTGCTATATGAAAAACTTTATGAGTTAGAGTCCCATCGAGA
TCAAATGATTGCAGAAGACAAAAGCATGGGATCGCCAATGGAGGAAAGGGAGAGATTGCTTAAG
CAGGTTAAAGAAGATAATCAGGAAATAGCCAGCATGGAGAGACAGTTAACAGATATAAAGGAAA
AAATAAATCAGTTTAGTGAAGAGATTAGACAACTTGACATGGATTTAGAGGAACACCAAGGTGA
AATGAATCAAAAATACAAGGAGCTTAAAAAAAGGGAAGAAAATATGGATGCTTTTATAGAGACT
TTTGAGGAAACGAAGAATCAGGAACTAGAGCGGAAGGCACAGATAGAAACCAGCATCATCACAC
TCTTAGAGCATTGCAGTCGGAATATAAATCGTATGAAACAGATATCCTCCATCACCAACCAAGA
GCTAAAGATGATGCAGGATGACCTCAGTTTTAAATCAACTGAAATGCAGAAGTCACAGACAACA
GCTAGGAATTTGACCTCAGACAGTCAGCGTCTACAGCTGGATCTCCAGAAAATGGAACTTTTGG
AAAGTAAGATGACAGAAGAGCAACAGTCTCTGAAAAACAAAATCAAGCAAATGACTGCTGACCT
GGAGACATACAGTGACCTGGCAGCTTTAAAATCATCAGCTGAAGAGAAGAAGAAGAAATTACAT
CAAGAAAGAACAGTATTGTCAACCCACAGAAATGCCTTTAAGAAAATAATGGAGAAGCTGACTA
CAGATTATGAGGCACTGAAAACACAACTTCAAGACAATGAGACACATGCTCAGCTTACAAACTT
GGAGAGGAAGTGGCAGCATCTGGAGCAAAATAATTTTGTAATGAAAGAGTTCATAGCAACCAAG
AGTCAGGAGAGTGATTACCAGCCAGTGATTAAAAATGTGATGAAGCAGATTGCAGAGTACAATA
AAACCATCATGGATGCTCTCCATAGTGCCAGCAGAAGCTGAAACGAAGTCCACTGAATCTACAA
GAATCCACAAGCATGCTAAAAGTAAATTAGCTTCCTCTTGAAGAGTTAGACCCCAGGTTTTTAA
ATGCCATGGTTTTGTGATCTCCTTGACGGAGAGATATCTTGCATAGTTAAATAATTCAATAAAT
GTTTGCATATAACTCA

hide sequence

RefSeq Acc Id:

XM_039109896 ⟹ XP_038965824

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	114,596,616 - 114,679,581 (+)	NCBI
mRatBN7.2	5	109,480,882 - 109,563,836 (+)	NCBI

RefSeq Acc Id:

XM_063287637 ⟹ XP_063143707

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	114,593,395 - 114,679,581 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001007002	(Get FASTA)	NCBI Sequence Viewer
	XP_017448856	(Get FASTA)	NCBI Sequence Viewer
	XP_038965824	(Get FASTA)	NCBI Sequence Viewer
	XP_063143707	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83611	(Get FASTA)	NCBI Sequence Viewer
	EDL97758	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000011336
	ENSRNOP00000011336.3
	ENSRNOP00000097814.1
	ENSRNOP00000111300.1

RefSeq Acc Id:

NP_001007002 ⟸ NM_001007001

- UniProtKB:

Q5XIR2 (UniProtKB/TrEMBL), F7FIM8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASNHKSAAPRPISRGGIGLTGRPPSGIRPPSGTVRVATAMPPATARPGSRGGPLGTGGVLSSQ
IKVADRPVTQQGLSGMKTGMKGPQRQILDKSYYLGLLRSKISELTTEINKLQKEIEMYNQENSV
YLSYEKRAETLAVEIKDFQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQNDRETQSMDVIFT
ERQAKEKQIRSVEEEVEQEKQAADGIIKNMSPEKQVKYIEMKTTNEKLLQELDTLQQQLDSLNI
KKESLETEIAHSQVKQEAVLLYEKLYELESHRDQMIAEDKSMGSPMEERERLLKQVKEDNQEIA
SMERQLTDIKEKINQFSEEIRQLDMDLEEHQGEMNQKYKELKKREENMDAFIETFEETKNQELE
RKAQIETSIITLLEHCSRNINRMKQISSITNQELKMMQDDLSFKSTEMQKSQTTARNLTSDSQR
LQLDLQKMELLESKMTEEQQSLKNKIKQMTADLETYSDLAALKSSAEEKKKKLHQERTVLSTHR
NAFKKIMEKLTTDYEALKTQLQDNETHAQLTNLERKWQHLEQNNFVMKEFIATKSQESDYQPVI
KNVMKQIAEYNKTIMDALHSASRS

hide sequence

RefSeq Acc Id:	XP_017448856 ⟸ XM_017593367
- Peptide Label:	isoform X1
- UniProtKB:	Q5XIR2 (UniProtKB/TrEMBL), F7FIM8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASNHKSAAPRPISRGGIGLTGRPPSGIRPPSGTVRVATAMPPATARPGSRGGPLGTGGVLSSQ IKVADRPVTQQGLSGMKTGMKGPQRQILDKSYYLGLLRSKISELTTEINKLQKEIEMYNQENSV YLSYEKRAETLAVEIKDFQGQLADYNMLVDKLNTNTEMEEVMNDYNMLKAQNDRETQSMDVIFT ERQAKEKQIRSVEEEVEQEKQAADGIIKNMSPEKQVKYIEMKTTNEKLLQELDTLQQQLDSLNI KKESLETEIAHSQVKQEAVLLYEKLYELESHRDQMIAEDKSMGSPMEERERLLKQVKEDNQEIA SMERQLTDIKEKINQFSEEIRQLDMDLEEHQGEMNQKYKELKKREENMDAFIETFEETKNQELE RKAQIETSIITLLEHCSRNINRMKQISSITNQELKMMQDDLSFKSTEMQKSQTTARNLTSDSQR LQLDLQKMELLESKMTEEQQSLKNKIKQMTADLETYSDLAALKSSAEEKKKKLHQERTVLSTHR NAFKKIMEKLTTDYEALKTQLQDNETHAQLTNLERKWQHLEQNNFVMKEFIATKSQESDYQPVI KNVMKQIAEYNKTIMDALHSASRS hide sequence

Ensembl Acc Id:

ENSRNOP00000011336 ⟸ ENSRNOT00000011336

RefSeq Acc Id:	XP_038965824 ⟸ XM_039109896
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000097814 ⟸ ENSRNOT00000099310

RefSeq Acc Id:	XP_063143707 ⟸ XM_063287637
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000111300 ⟸ ENSRNOT00000172970

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIR2-F1-model_v2	AlphaFold	Q5XIR2	1-600	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693841

Promoter ID:

EPDNEW_R4365

Type:

initiation region

Name:

Ift74_1

Description:

intraflagellar transport 74

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	113,592,973 - 113,593,033	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359704	AgrOrtholog
BioCyc Gene	G2FUF-40706	BioCyc
Ensembl Genes	ENSRNOG00000008075	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000011336	ENTREZGENE
	ENSRNOT00000011336.6	UniProtKB/TrEMBL
	ENSRNOT00000099310.2	UniProtKB/TrEMBL
	ENSRNOT00000172970.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.1490	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7133514	IMAGE-MGC_LOAD
InterPro	IFT74	UniProtKB/TrEMBL
KEGG Report	rno:313365	UniProtKB/TrEMBL
MGC_CLONE	MGC:94371	IMAGE-MGC_LOAD
NCBI Gene	313365	ENTREZGENE
PANTHER	INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG	UniProtKB/TrEMBL
	PTHR31432	UniProtKB/TrEMBL
PhenoGen	Ift74	PhenoGen
RatGTEx	ENSRNOG00000008075	RatGTEx
UniProt	A0A8I6ANR2_RAT	UniProtKB/TrEMBL
	A0ABK0M2L6_RAT	UniProtKB/TrEMBL
	F7FIM8	ENTREZGENE, UniProtKB/TrEMBL
	Q5XIR2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-07-09	Ift74	intraflagellar transport 74	Ift74	intraflagellar transport 74 homolog (Chlamydomonas)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Ift74	intraflagellar transport 74 homolog (Chlamydomonas)	Ccdc2	coiled-coil domain containing 2	Symbol and Name updated	1299863	APPROVED
2005-07-29	Ccdc2	coiled-coil domain containing 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - MGI

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