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Gene: Slc12a7 (solute carrier family 12 member 7) Rattus norvegicus

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Symbol:

Slc12a7

Name:

solute carrier family 12 member 7

RGD ID:

1359672

Description:

Predicted to enable potassium:chloride symporter activity and protein kinase binding activity. Involved in cell volume homeostasis. Predicted to be located in membrane and synapse. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Orthologous to human SLC12A7 (solute carrier family 12 member 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

electroneutral potassium-chloride cotransporter 4; furosemide-sensitive KCl cotransporter 4; K-Cl cotransporter 4; K-Cl cotransporter KCC4; Kcc4; LOC308069; solute carrier family 12 (potassium/chloride transporter), member 7; solute carrier family 12 (potassium/chloride transporters), member 7; solute carrier family 12, member 7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	31,301,243 - 31,382,825 (-)	NCBI		GRCr8
mRatBN7.2	1	29,472,692 - 29,554,246 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	29,472,692 - 29,554,302 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	29,273,827 - 29,327,212 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	35,273,677 - 35,327,062 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	29,474,455 - 29,527,840 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	32,086,755 - 32,167,950 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	32,086,755 - 32,141,036 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	33,511,432 - 33,592,624 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	30,281,826 - 30,334,183 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	30,283,750 - 30,337,129 (-)	NCBI
Celera	1	28,120,766 - 28,174,109 (-)	NCBI		Celera
Cytogenetic Map	1	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc12a7	Rat	autosomal dominant dyskeratosis congenita 2		ISO	RGD:1348814	8554872	ClinVar Annotator: match by term: Dyskeratosis congenita, autosomal dominant 2	ClinVar	PMID:12629597\|PMID:16247010\|PMID:17460043\|PMID:28492532
Slc12a7	Rat	dopamine transporter deficiency syndrome		ISO	RGD:1348814	8554872	ClinVar Annotator: match by term: Parkinsonism-dystonia, infantile	ClinVar	PMID:21112253\|PMID:28492532
Slc12a7	Rat	interstitial lung disease 2		ISO	RGD:1348814	8554872	ClinVar Annotator: match by term: Interstitial lung disease 2	ClinVar	PMID:12629597\|PMID:28492532

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc12a7	Rat	autism spectrum disorder		ISO	RGD:1348814	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:35663546
Slc12a7	Rat	urinary bladder cancer		ISO	RGD:1348814	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:26039340

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc12a7	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	RGD:1550903	6480464	[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SLC12A7 mRNA	CTD	PMID:22206623
Slc12a7	Rat	1-Hydroxypyrene	decreases expression	ISO	RGD:1348814	6480464	1-hydroxypyrene results in decreased expression of SLC12A7 mRNA	CTD	PMID:21854004
Slc12a7	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	EXP		6480464	Tetrachlorodibenzodioxin results in increased expression of SLC12A7 mRNA	CTD	PMID:16960034
Slc12a7	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:1550903	6480464	Tetrachlorodibenzodioxin results in increased expression of SLC12A7 mRNA	CTD	PMID:16960034\|PMID:21496263
Slc12a7	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:1348814	6480464	Tetrachlorodibenzodioxin results in increased expression of SLC12A7 mRNA	CTD	PMID:19684285\|PMID:20106945\|PMID:21496263\|PMID:21632981
Slc12a7	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1550903	6480464	Tetrachlorodibenzodioxin affects the expression of SLC12A7 mRNA	CTD	PMID:21570461
Slc12a7	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1348814	6480464	Tetrachlorodibenzodioxin affects the expression of SLC12A7 mRNA	CTD	PMID:22298810
Slc12a7	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of SLC12A7 mRNA	CTD	PMID:19692669
Slc12a7	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	ISO	RGD:1550903	6480464	Tetrachlorodibenzodioxin results in decreased expression of SLC12A7 mRNA	CTD	PMID:19684285
Slc12a7	Rat	2,4-dinitrotoluene	affects expression	EXP		6480464	2,4-dinitrotoluene affects the expression of SLC12A7 mRNA	CTD	PMID:21346803
Slc12a7	Rat	2,6-dinitrotoluene	affects expression	EXP		6480464	2,6-dinitrotoluene affects the expression of SLC12A7 mRNA	CTD	PMID:21346803
Slc12a7	Rat	2-palmitoylglycerol	increases expression	ISO	RGD:1348814	6480464	2-palmitoylglycerol results in increased expression of SLC12A7 mRNA	CTD	PMID:37199045
Slc12a7	Rat	4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid	decreases activity	ISO	RGD:1550903	6480464	4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of SLC12A7 protein	CTD	PMID:10913127
Slc12a7	Rat	4-hydroxyphenyl retinamide	increases expression	ISO	RGD:1550903	6480464	Fenretinide results in increased expression of SLC12A7 mRNA	CTD	PMID:28973697
Slc12a7	Rat	4-tert-Octylphenol	increases expression	EXP		6480464	4-tert-octylphenol results in increased expression of SLC12A7 mRNA	CTD	PMID:17011747
Slc12a7	Rat	6-propyl-2-thiouracil	increases expression	EXP		6480464	Propylthiouracil results in increased expression of SLC12A7 mRNA	CTD	PMID:24780913
Slc12a7	Rat	amphetamine	decreases expression	EXP		6480464	Amphetamine results in decreased expression of SLC12A7 mRNA	CTD	PMID:30779732
Slc12a7	Rat	antirheumatic drug	decreases expression	ISO	RGD:1348814	6480464	Antirheumatic Agents results in decreased expression of SLC12A7 mRNA	CTD	PMID:24449571
Slc12a7	Rat	arsane	affects methylation	ISO	RGD:1348814	6480464	Arsenic affects the methylation of SLC12A7 gene	CTD	PMID:25304211
Slc12a7	Rat	arsenic atom	affects methylation	ISO	RGD:1348814	6480464	Arsenic affects the methylation of SLC12A7 gene	CTD	PMID:25304211
Slc12a7	Rat	atrazine	decreases expression	EXP		6480464	Atrazine results in decreased expression of SLC12A7 mRNA	CTD	PMID:36841081
Slc12a7	Rat	atrazine	affects methylation	EXP		6480464	Atrazine affects the methylation of SLC12A7 gene	CTD	PMID:35440735
Slc12a7	Rat	Azoxymethane	multiple interactions	ISO	RGD:1550903	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC12A7 more ...	CTD	PMID:29950665
Slc12a7	Rat	barium(0)	decreases activity	ISO	RGD:1550903	6480464	Barium results in decreased activity of SLC12A7 protein	CTD	PMID:10913127
Slc12a7	Rat	benzo[a]pyrene	multiple interactions	ISO	RGD:1550903	6480464	Benzo(a)pyrene promotes the reaction [AHR protein binds to SLC12A7 promoter]	CTD	PMID:19654925
Slc12a7	Rat	benzo[a]pyrene	increases methylation	ISO	RGD:1348814	6480464	Benzo(a)pyrene results in increased methylation of SLC12A7 exon	CTD	PMID:27901495
Slc12a7	Rat	benzo[a]pyrene	affects methylation	ISO	RGD:1348814	6480464	Benzo(a)pyrene affects the methylation of SLC12A7 promoter	CTD	PMID:27901495
Slc12a7	Rat	benzo[a]pyrene	decreases methylation	ISO	RGD:1348814	6480464	Benzo(a)pyrene results in decreased methylation of SLC12A7 3' UTR	CTD	PMID:27901495
Slc12a7	Rat	beta-lapachone	decreases expression	ISO	RGD:1348814	6480464	beta-lapachone results in decreased expression of SLC12A7 mRNA	CTD	PMID:38218311
Slc12a7	Rat	bis(2-ethylhexyl) phthalate	multiple interactions	ISO	RGD:1550903	6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ...	CTD	PMID:39150890
Slc12a7	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of SLC12A7 mRNA	CTD	PMID:25181051
Slc12a7	Rat	bisphenol A	affects methylation	ISO	RGD:1348814	6480464	bisphenol A affects the methylation of SLC12A7 gene	CTD	PMID:31601247
Slc12a7	Rat	bisphenol A	increases methylation	EXP		6480464	bisphenol A results in increased methylation of SLC12A7 gene	CTD	PMID:28505145
Slc12a7	Rat	bisphenol F	decreases expression	ISO	RGD:1550903	6480464	bisphenol F results in decreased expression of SLC12A7 mRNA	CTD	PMID:38685157
Slc12a7	Rat	bumetanide	decreases activity	ISO	RGD:1550903	6480464	Bumetanide results in decreased activity of SLC12A7 protein	CTD	PMID:10913127
Slc12a7	Rat	Butylbenzyl phthalate	multiple interactions	ISO	RGD:1550903	6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ...	CTD	PMID:39150890
Slc12a7	Rat	C60 fullerene	affects expression	EXP		6480464	fullerene C60 affects the expression of SLC12A7 mRNA	CTD	PMID:19167457
Slc12a7	Rat	cadmium dichloride	increases expression	ISO	RGD:1348814	6480464	Cadmium Chloride results in increased expression of SLC12A7 mRNA	CTD	PMID:38568856
Slc12a7	Rat	chromium(6+)	affects expression	ISO	RGD:1550903	6480464	chromium hexavalent ion affects the expression of SLC12A7 mRNA	CTD	PMID:28472532
Slc12a7	Rat	cisplatin	multiple interactions	ISO	RGD:1348814	6480464	[Cisplatin co-treated with jinfukang] results in increased expression of SLC12A7 mRNA	CTD	PMID:27392435
Slc12a7	Rat	Cuprizon	decreases expression	EXP		6480464	Cuprizone results in decreased expression of SLC12A7 mRNA	CTD	PMID:27523638
Slc12a7	Rat	Cuprizon	increases expression	EXP		6480464	Cuprizone results in increased expression of SLC12A7 mRNA	CTD	PMID:26577399
Slc12a7	Rat	cyclosporin A	increases expression	ISO	RGD:1348814	6480464	Cyclosporine results in increased expression of SLC12A7 mRNA	CTD	PMID:20106945
Slc12a7	Rat	cyclosporin A	decreases methylation	ISO	RGD:1348814	6480464	Cyclosporine results in decreased methylation of SLC12A7 promoter	CTD	PMID:27989131
Slc12a7	Rat	dextran sulfate	multiple interactions	ISO	RGD:1550903	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC12A7 more ...	CTD	PMID:29950665
Slc12a7	Rat	diazinon	increases methylation	ISO	RGD:1348814	6480464	Diazinon results in increased methylation of SLC12A7 gene	CTD	PMID:22964155
Slc12a7	Rat	dibutyl phthalate	decreases expression	EXP		6480464	Dibutyl Phthalate results in decreased expression of SLC12A7 mRNA	CTD	PMID:21266533
Slc12a7	Rat	dibutyl phthalate	multiple interactions	ISO	RGD:1550903	6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ...	CTD	PMID:39150890
Slc12a7	Rat	diethyl phthalate	multiple interactions	ISO	RGD:1550903	6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ...	CTD	PMID:39150890
Slc12a7	Rat	diethylstilbestrol	increases expression	EXP		6480464	Diethylstilbestrol results in increased expression of SLC12A7 mRNA	CTD	PMID:17011747
Slc12a7	Rat	diethylstilbestrol	decreases expression	EXP		6480464	Diethylstilbestrol results in decreased expression of SLC12A7 mRNA	CTD	PMID:21658437
Slc12a7	Rat	diisobutyl phthalate	multiple interactions	ISO	RGD:1550903	6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ...	CTD	PMID:39150890
Slc12a7	Rat	diisononyl phthalate	multiple interactions	ISO	RGD:1550903	6480464	[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with diisononyl phthalate co-treated with Dibutyl Phthalate co-treated more ...	CTD	PMID:39150890
Slc12a7	Rat	dorsomorphin	multiple interactions	ISO	RGD:1348814	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Slc12a7	Rat	endosulfan	decreases expression	EXP		6480464	Endosulfan results in decreased expression of SLC12A7 mRNA	CTD	PMID:29391264
Slc12a7	Rat	epoxiconazole	decreases expression	ISO	RGD:1550903	6480464	epoxiconazole results in decreased expression of SLC12A7 mRNA	CTD	PMID:35436446
Slc12a7	Rat	ethanol	increases expression	ISO	RGD:1550903	6480464	Ethanol results in increased expression of SLC12A7 mRNA	CTD	PMID:30319688
Slc12a7	Rat	fenamidone	increases expression	ISO	RGD:1550903	6480464	fenamidone results in increased expression of SLC12A7 mRNA	CTD	PMID:27029645
Slc12a7	Rat	fipronil	increases expression	EXP		6480464	fipronil results in increased expression of SLC12A7 mRNA	CTD	PMID:34044035
Slc12a7	Rat	flutamide	decreases expression	EXP		6480464	Flutamide results in decreased expression of SLC12A7 mRNA	CTD	PMID:24136188
Slc12a7	Rat	folic acid	multiple interactions	ISO	RGD:1550903	6480464	[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SLC12A7 mRNA	CTD	PMID:22206623
Slc12a7	Rat	FR900359	affects phosphorylation	ISO	RGD:1348814	6480464	FR900359 affects the phosphorylation of SLC12A7 protein	CTD	PMID:37730182
Slc12a7	Rat	furosemide	decreases activity	ISO	RGD:1550903	6480464	Furosemide results in decreased activity of SLC12A7 protein	CTD	PMID:10913127
Slc12a7	Rat	hydrogen cyanide	decreases expression	ISO	RGD:1550903	6480464	Hydrogen Cyanide results in decreased expression of SLC12A7 mRNA	CTD	PMID:33914522
Slc12a7	Rat	leflunomide	increases expression	ISO	RGD:1348814	6480464	leflunomide results in increased expression of SLC12A7 mRNA	CTD	PMID:28988120
Slc12a7	Rat	Licochalcone B	decreases expression	ISO	RGD:1348814	6480464	licochalcone B results in decreased expression of SLC12A7 mRNA	CTD	PMID:33647349
Slc12a7	Rat	menadione	affects expression	ISO	RGD:1348814	6480464	Vitamin K 3 affects the expression of SLC12A7 mRNA	CTD	PMID:20044591
Slc12a7	Rat	methotrexate	decreases expression	ISO	RGD:1348814	6480464	Methotrexate results in decreased expression of SLC12A7 mRNA	CTD	PMID:24449571
Slc12a7	Rat	N-methyl-4-phenylpyridinium	increases expression	ISO	RGD:1348814	6480464	1-Methyl-4-phenylpyridinium results in increased expression of SLC12A7 mRNA	CTD	PMID:24810058
Slc12a7	Rat	nickel sulfate	increases expression	ISO	RGD:1348814	6480464	nickel sulfate results in increased expression of SLC12A7 mRNA	CTD	PMID:22714537
Slc12a7	Rat	okadaic acid	increases expression	ISO	RGD:1348814	6480464	Okadaic Acid results in increased expression of SLC12A7 mRNA	CTD	PMID:38832940
Slc12a7	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in increased expression of SLC12A7 mRNA	CTD	PMID:25729387
Slc12a7	Rat	p-tert-Amylphenol	increases expression	EXP		6480464	4-tert-octylphenol results in increased expression of SLC12A7 mRNA	CTD	PMID:17011747
Slc12a7	Rat	paracetamol	affects expression	ISO	RGD:1550903	6480464	Acetaminophen affects the expression of SLC12A7 mRNA	CTD	PMID:17562736
Slc12a7	Rat	paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of SLC12A7 mRNA	CTD	PMID:33387578
Slc12a7	Rat	perfluorohexanesulfonic acid	decreases expression	ISO	RGD:1550903	6480464	perfluorohexanesulfonic acid results in decreased expression of SLC12A7 mRNA	CTD	PMID:37995155
Slc12a7	Rat	pirinixic acid	decreases expression	ISO	RGD:1550903	6480464	pirinixic acid results in decreased expression of SLC12A7 mRNA	CTD	PMID:18445702
Slc12a7	Rat	pirinixic acid	increases expression	ISO	RGD:1550903	6480464	pirinixic acid results in increased expression of SLC12A7 mRNA	CTD	PMID:18301758
Slc12a7	Rat	potassium cyanide	decreases expression	ISO	RGD:1550903	6480464	Potassium Cyanide results in decreased expression of SLC12A7 mRNA	CTD	PMID:33914522
Slc12a7	Rat	pregnenolone 16alpha-carbonitrile	decreases expression	EXP		6480464	Pregnenolone Carbonitrile results in decreased expression of SLC12A7 mRNA	CTD	PMID:19162173
Slc12a7	Rat	propiconazole	decreases expression	ISO	RGD:1550903	6480464	propiconazole results in decreased expression of SLC12A7 mRNA	CTD	PMID:21278054
Slc12a7	Rat	resveratrol	increases expression	ISO	RGD:1550903	6480464	resveratrol results in increased expression of SLC12A7 protein	CTD	PMID:25505154
Slc12a7	Rat	rotenone	increases expression	ISO	RGD:1348814	6480464	Rotenone results in increased expression of SLC12A7 mRNA	CTD	PMID:29955902
Slc12a7	Rat	SB 431542	multiple interactions	ISO	RGD:1348814	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Slc12a7	Rat	silicon dioxide	increases expression	ISO	RGD:1348814	6480464	Silicon Dioxide results in increased expression of SLC12A7 mRNA	CTD	PMID:25351596
Slc12a7	Rat	sulforaphane	increases expression	ISO	RGD:1348814	6480464	sulforaphane results in increased expression of SLC12A7 mRNA	CTD	PMID:31838189
Slc12a7	Rat	sunitinib	decreases expression	ISO	RGD:1348814	6480464	Sunitinib results in decreased expression of SLC12A7 mRNA	CTD	PMID:31533062
Slc12a7	Rat	tetrachloromethane	decreases expression	EXP		6480464	Carbon Tetrachloride results in decreased expression of SLC12A7 mRNA	CTD	PMID:31150632
Slc12a7	Rat	thioacetamide	decreases expression	EXP		6480464	Thioacetamide results in decreased expression of SLC12A7 mRNA	CTD	PMID:34492290
Slc12a7	Rat	titanium dioxide	multiple interactions	ISO	RGD:1550903	6480464	[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of SLC12A7 more ...	CTD	PMID:29950665
Slc12a7	Rat	titanium dioxide	decreases methylation	ISO	RGD:1550903	6480464	titanium dioxide results in decreased methylation of SLC12A7 gene; titanium dioxide results in decreased methylation more ...	CTD	PMID:35295148
Slc12a7	Rat	topotecan	increases expression	EXP		6480464	Topotecan results in increased expression of SLC12A7 mRNA	CTD	PMID:25729387
Slc12a7	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in increased expression of SLC12A7 mRNA	CTD	PMID:25729387
Slc12a7	Rat	trichlormethiazide	decreases activity	ISO	RGD:1550903	6480464	Trichlormethiazide results in decreased activity of SLC12A7 protein	CTD	PMID:10913127
Slc12a7	Rat	triphenyl phosphate	affects expression	ISO	RGD:1348814	6480464	triphenyl phosphate affects the expression of SLC12A7 mRNA	CTD	PMID:37042841
Slc12a7	Rat	Triptolide	increases expression	EXP		6480464	triptolide results in increased expression of SLC12A7 protein	CTD	PMID:32519852
Slc12a7	Rat	valproic acid	affects expression	ISO	RGD:1348814	6480464	Valproic Acid affects the expression of SLC12A7 mRNA	CTD	PMID:25979313
Slc12a7	Rat	valproic acid	multiple interactions	ISO	RGD:1348814	6480464	[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ...	CTD	PMID:27188386
Slc12a7	Rat	valproic acid	decreases expression	ISO	RGD:1348814	6480464	Valproic Acid results in decreased expression of SLC12A7 mRNA; Valproic Acid results in decreased expression more ...	CTD	PMID:23179753\|PMID:26272509\|PMID:29501571
Slc12a7	Rat	vanadium atom	decreases expression	ISO	RGD:1348814	6480464	Vanadium results in decreased expression of SLC12A7 mRNA	CTD	PMID:19000753
Slc12a7	Rat	vanadium(0)	decreases expression	ISO	RGD:1348814	6480464	Vanadium results in decreased expression of SLC12A7 mRNA	CTD	PMID:19000753
Slc12a7	Rat	vinclozolin	increases methylation	EXP		6480464	vinclozolin results in increased methylation of SLC12A7 gene	CTD	PMID:31079544\|PMID:31682807

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc12a7	Rat	cell volume homeostasis		IMP		1558104		RGD
Slc12a7	Rat	cell volume homeostasis	involved_in	IBA	MGI:101924\|PANTHER:PTN000214719\|RGD:1359672\|RGD:620809\|UniProtKB:Q13621\|UniProtKB:Q9UHW9	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc12a7	Rat	cellular response to glucose stimulus	involved_in	ISO	RGD:1550903	1624291	PMID:24089410	RGD	PMID:24089410
Slc12a7	Rat	chemical synaptic transmission	involved_in	IBA	MGI:1862037\|PANTHER:PTN000930408	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc12a7	Rat	chloride ion homeostasis	involved_in	IBA	MGI:101924\|MGI:2135960\|PANTHER:PTN000214719\|UniProtKB:Q9H2X9\|ZFIN:ZDB-GENE-060503-425	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc12a7	Rat	chloride transmembrane transport	involved_in	IEA	GO:0015377	1600115	GO_REF:0000108	GOC	GO_REF:0000108
Slc12a7	Rat	chloride transmembrane transport	involved_in	IBA	MGI:101924\|PANTHER:PTN000214719\|WB:WBGene00006504	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc12a7	Rat	monoatomic ion transport	involved_in	IEA	UniProtKB-KW:KW-0406	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc12a7	Rat	monoatomic ion transport	involved_in	IEA	InterPro:IPR000076\|InterPro:IPR004842\|InterPro:IPR018491	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc12a7	Rat	monoatomic ion transport	involved_in	IEA	InterPro:IPR004842	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc12a7	Rat	potassium ion homeostasis	involved_in	IBA	MGI:101924\|MGI:2135960\|PANTHER:PTN000214719\|SGD:S000000439	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc12a7	Rat	potassium ion import across plasma membrane	involved_in	ISO	RGD:1550903	1624291	PMID:12657561	RGD	PMID:12657561
Slc12a7	Rat	potassium ion import across plasma membrane	involved_in	IBA	MGI:101924\|MGI:1342283\|PANTHER:PTN000214719\|UniProtKB:Q9UHW9	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc12a7	Rat	potassium ion transmembrane transport	involved_in	IEA	GO:0015379	1600115	GO_REF:0000108	GOC	GO_REF:0000108
Slc12a7	Rat	potassium ion transmembrane transport	involved_in	ISO	RGD:1550903	1624291	PMID:11551954	RGD	PMID:11551954
Slc12a7	Rat	potassium ion transmembrane transport	involved_in	ISS	UniProtKB:Q9WVL3	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Slc12a7	Rat	potassium ion transport	involved_in	IEA	UniProtKB-KW:KW-0633	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc12a7	Rat	transmembrane transport	involved_in	IEA	InterPro:IPR004841	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc12a7	Rat	membrane	located_in	IEA	UniProtKB-SubCell:SL-0162	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Slc12a7	Rat	membrane	located_in	IEA	InterPro:IPR004841\|InterPro:IPR004842	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc12a7	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc12a7	Rat	membrane	located_in	IEA	InterPro:IPR000076\|InterPro:IPR004841\|InterPro:IPR004842\|InterPro:IPR018491	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc12a7	Rat	plasma membrane	located_in	IEA	UniProtKB-SubCell:SL-0039	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Slc12a7	Rat	plasma membrane	located_in	IEA	UniProtKB-KW:KW-1003	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc12a7	Rat	plasma membrane	is_active_in	IBA	MGI:1862037\|MGI:2135960\|PANTHER:PTN000930407\|RGD:620811\|UniProtKB:Q9UHW9\|WB:WBGene00019289	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc12a7	Rat	protein-containing complex	part_of	ISO	RGD:1348814	1624291	PMID:28246125	RGD	PMID:28246125
Slc12a7	Rat	synapse	located_in	IEA	GO:0007268	1600115	GO_REF:0000108	GOC	GO_REF:0000108

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Slc12a7	Rat	chloride:monoatomic cation symporter activity	enables	IEA	InterPro:IPR004842	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc12a7	Rat	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc12a7	Rat	potassium:chloride symporter activity		TAS		1558104		RGD
Slc12a7	Rat	potassium:chloride symporter activity	enables	ISO	RGD:1550903	1624291	PMID:11551954, PMID:12106695, PMID:12657561	RGD	PMID:11551954\|PMID:12106695\|PMID:12657561
Slc12a7	Rat	potassium:chloride symporter activity	enables	IBA	FB:FBgn0036279\|FB:FBgn0261794\|MGI:103150\|MGI:1309465\|MGI:1342283\|MGI:1862037\|MGI:2135960\|PANTHER:PTN000214719\|RGD:3685\|RGD:620809\|RGD:620811\|SGD:S000000439\|UniProtKB:P55011\|UniProtKB:Q13621\|UniProtKB:Q9H2X9\|UniProtKB:Q9UHW9\|UniProtKB:Q9UP95\|WB:WBGene00006504\|WB:WBGene00019205	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Slc12a7	Rat	potassium:chloride symporter activity	enables	IEA	InterPro:IPR000076	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Slc12a7	Rat	potassium:chloride symporter activity	enables	ISS	UniProtKB:Q9WVL3	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Slc12a7	Rat	protein binding	enables	ISO	RGD:1348814,UniProtKB:Q9Y666-2	1624291	UniProtKB:P08034\|UniProtKB:P41143\|UniProtKB:P55061\|UniProtKB:Q14973\|UniProtKB:Q3KNW5\|UniProtKB:Q5J8X5\|UniProtKB:Q5XKR4\|UniProtKB:Q969K7\|UniProtKB:Q96EC8\|UniProtKB:Q96Q45-2\|UniProtKB:Q9BVK8\|UniProtKB:Q9BZJ8\|UniProtKB:Q9NQQ7-3 PMID:32296183	RGD	PMID:32296183
Slc12a7	Rat	protein kinase binding	enables	ISO	RGD:1348814	1624291	UniProtKB:Q9UEW8 PMID:24393035	RGD	PMID:24393035
Slc12a7	Rat	symporter activity	enables	IEA	UniProtKB-KW:KW-0769	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Slc12a7	Rat	transmembrane transporter activity	enables	IEA	InterPro:IPR018491	1600115	GO_REF:0000002	InterPro	GO_REF:0000002

#	Reference Title	Reference Citation
1.	Expression of K+-Cl- cotransporters in the alpha-cells of rat endocrine pancreas.	Davies SL, etal., Biochim Biophys Acta 2004 Nov 17;1667(1):7-14.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

PMID:12657561	PMID:16872584	PMID:18984587	PMID:19923415	PMID:19932740	PMID:23376777	PMID:24089410	PMID:24393035	PMID:28246125

Slc12a7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	31,301,243 - 31,382,825 (-)	NCBI		GRCr8
mRatBN7.2	1	29,472,692 - 29,554,246 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	29,472,692 - 29,554,302 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	29,273,827 - 29,327,212 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	35,273,677 - 35,327,062 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	29,474,455 - 29,527,840 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	32,086,755 - 32,167,950 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	32,086,755 - 32,141,036 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	33,511,432 - 33,592,624 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	30,281,826 - 30,334,183 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	30,283,750 - 30,337,129 (-)	NCBI
Celera	1	28,120,766 - 28,174,109 (-)	NCBI		Celera
Cytogenetic Map	1	p11	NCBI

SLC12A7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	1,050,384 - 1,155,899 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	1,050,384 - 1,112,063 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	1,050,499 - 1,112,178 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	1,103,489 - 1,165,172 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	1,103,499 - 1,165,109	NCBI
Celera	5	1,087,603 - 1,137,533 (-)	NCBI		Celera
Cytogenetic Map	5	p15.33	NCBI
HuRef	5	1,032,225 - 1,074,697 (-)	NCBI		HuRef
CHM1_1	5	1,050,309 - 1,109,639 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	955,618 - 1,061,601 (-)	NCBI		T2T-CHM13v2.0

Slc12a7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	73,881,172 - 73,964,873 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	73,881,213 - 73,964,873 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	73,733,052 - 73,816,754 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	73,733,094 - 73,816,754 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	73,901,145 - 73,954,191 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	74,229,699 - 74,282,745 (+)	NCBI		MGSCv36	mm8
Celera	13	76,093,026 - 76,146,073 (+)	NCBI		Celera
Cytogenetic Map	13	C1	NCBI
cM Map	13	40.15	NCBI

Slc12a7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955504	530,343 - 568,569 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955504	529,183 - 589,728 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC12A7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	1,297,648 - 1,358,631 (-)	NCBI		NHGRI_mPanPan1-v2
PanPan1.1 Ensembl	5	1,094,769 - 1,147,759 (-)	Ensembl	panpan1.1		panPan2

SLC12A7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	34	11,411,521 - 11,442,175 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	34	11,411,626 - 11,440,957 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	34	15,916,047 - 15,953,273 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	34	11,306,873 - 11,344,109 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	34	11,278,297 - 11,369,935 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	34	11,357,510 - 11,394,729 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	34	11,337,208 - 11,374,410 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	34	11,548,126 - 11,585,343 (+)	NCBI		UU_Cfam_GSD_1.0

Slc12a7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	244,468,120 - 244,505,057 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936815	636,184 - 665,019 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936815	629,185 - 666,342 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC12A7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	79,357,010 - 79,396,656 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	79,356,868 - 79,396,652 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SLC12A7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	890,213 - 989,650 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	890,202 - 964,263 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	35,446,259 - 35,506,531 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc12a7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	506,040 - 544,365 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624751	508,902 - 544,319 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Slc12a7
249 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	255
Count of miRNA genes:	158
Interacting mature miRNAs:	198
Transcripts:	ENSRNOT00000022635
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1357397	Bw41	Body weight QTL 41	4.19	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	22340647	49361612	Rat
1578650	Bmd6	Bone mineral density QTL 6	12.2		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	1	509108	43284926	Rat
1578651	Bmd7	Bone mineral density QTL 7	14.2		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	1	509108	43284926	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	11481312	82174945	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
7421626	Bp360	Blood pressure QTL 360		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	4393289	49393289	Rat
1357400	Bw62	Body weight QTL62	4.05		inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	1	22340647	67340647	Rat
2313070	Bss52	Bone structure and strength QTL 52	4.4	0.0001	body length (VT:0001256)	body length (CMO:0000013)	1	1	32356093	Rat
1357401	Bw43	Body weight QTL 43	3.75		body mass (VT:0001259)	body weight (CMO:0000012)	1	22340647	49361612	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
631494	Bp95	Blood pressure QTL 95	40	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	16206210	49268520	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11481312	82174945	Rat
5684998	Bss101	Bone structure and strength QTL 101	3.6		tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	1	15431621	49361612	Rat
5684999	Bss102	Bone structure and strength QTL 102	5.5	7e-07	tibia strength trait (VT:1000284)	tibia stiffness (CMO:0001735)	1	15431621	49361612	Rat
1300167	Hrtrt2	Heart rate QTL 2	4.35		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	11481312	75088344	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11481312	82174945	Rat
2317755	Glom22	Glomerulus QTL 22	3.8		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	11481482	32355910	Rat
1578756	Iddm22	Insulin dependent diabetes mellitus QTL 22	2.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	11835181	56835181	Rat
631508	Sald1	Serum aldosterone level QTL 1	3.7		blood aldosterone amount (VT:0005346)	serum aldosterone level (CMO:0000487)	1	9856001	54856001	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	28879780	78430678	Rat
2313090	Bmd69	Bone mineral density QTL 69	4.4	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	1	32356093	Rat
724520	Bp145	Blood pressure QTL 145	2.1	0.0024	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	20784828	65784828	Rat
1558642	Prcr2	Prostate cancer resistance QTL 2	4.3		prostate integrity trait (VT:0010571)	area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)	1	20763158	44095856	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11481312	82174945	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11481312	82174945	Rat
738020	Pia8	Pristane induced arthritis QTL 8	4.7		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	1	65833076	Rat
1600360	Mcs16	Mammary carcinoma susceptibility QTL 16	2.4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	2244390	43433040	Rat
1578669	Bss9	Bone structure and strength QTL 9	6.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	1	509108	43284926	Rat
2302038	Pia31	Pristane induced arthritis QTL 31	5.5	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)	1	10992065	55992065	Rat
634353	Rends2	Renal damage susceptibility QTL 2		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	1	19333571	56983283	Rat
2313053	Bss51	Bone structure and strength QTL 51	3.8	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	1	32356093	Rat

D1Rat9

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	1	31,350,043 - 31,350,168 (+)	Marker Load Pipeline
mRatBN7.2	1	29,521,493 - 29,521,616 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	32,135,556 - 32,135,680	NCBI	Rnor6.0
Rnor_5.0	1	33,560,233 - 33,560,357	UniSTS	Rnor5.0
RGSC_v3.4	1	30,329,603 - 30,329,728	RGD	RGSC3.4
RGSC_v3.4	1	30,329,604 - 30,329,728	UniSTS	RGSC3.4
RGSC_v3.1	1	30,332,549 - 30,332,673	RGD
Celera	1	28,169,528 - 28,169,652	UniSTS
RH 3.4 Map	1	347.42	RGD
RH 3.4 Map	1	347.42	UniSTS
RH 2.0 Map	1	221.4	RGD
SHRSP x BN Map	1	15.98	RGD
FHH x ACI Map	1	23.2999	RGD
Cytogenetic Map	1	p11	UniSTS

D1Cebr11

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	29,515,545 - 29,515,709 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	32,129,608 - 32,129,771	NCBI	Rnor6.0
Rnor_5.0	1	33,554,285 - 33,554,448	UniSTS	Rnor5.0
RGSC_v3.4	1	30,323,656 - 30,323,819	UniSTS	RGSC3.4
Celera	1	28,163,580 - 28,163,743	UniSTS
Cytogenetic Map	1	p11	UniSTS

D1Cebr12

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	29,506,202 - 29,506,405 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	32,120,265 - 32,120,467	NCBI	Rnor6.0
Rnor_5.0	1	33,544,942 - 33,545,144	UniSTS	Rnor5.0
RGSC_v3.4	1	30,314,313 - 30,314,515	UniSTS	RGSC3.4
Celera	1	28,154,237 - 28,154,439	UniSTS
Cytogenetic Map	1	p11	UniSTS

RH128389

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	29,472,942 - 29,473,135 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	32,087,006 - 32,087,198	NCBI	Rnor6.0
Rnor_5.0	1	33,511,683 - 33,511,875	UniSTS	Rnor5.0
RGSC_v3.4	1	30,281,055 - 30,281,247	UniSTS	RGSC3.4
Celera	1	28,121,017 - 28,121,209	UniSTS
Cytogenetic Map	1	p11	UniSTS

RH133369

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	29,472,794 - 29,472,980 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	32,086,858 - 32,087,043	NCBI	Rnor6.0
Rnor_5.0	1	33,511,535 - 33,511,720	UniSTS	Rnor5.0
RGSC_v3.4	1	30,280,907 - 30,281,092	UniSTS	RGSC3.4
Celera	1	28,120,869 - 28,121,054	UniSTS
Cytogenetic Map	1	p11	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001013144	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006227789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288386	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC142421	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AH013297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY429042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC086339	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000022635 ⟹ ENSRNOP00000022635

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	29,472,692 - 29,526,073 (-)	Ensembl
Rnor_6.0 Ensembl	1	32,086,755 - 32,140,137 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078039 ⟹ ENSRNOP00000074714

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	29,472,692 - 29,554,302 (-)	Ensembl
Rnor_6.0 Ensembl	1	32,088,259 - 32,141,036 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000081339 ⟹ ENSRNOP00000071618

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	29,472,694 - 29,526,072 (-)	Ensembl
Rnor_6.0 Ensembl	1	32,086,757 - 32,140,136 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112535 ⟹ ENSRNOP00000088698

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	29,472,702 - 29,526,095 (-)	Ensembl

RefSeq Acc Id:

NM_001013144 ⟹ NP_001013162

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	31,301,243 - 31,354,625 (-)	NCBI
mRatBN7.2	1	29,472,692 - 29,526,073 (-)	NCBI
Rnor_6.0	1	32,086,755 - 32,140,137 (-)	NCBI
Rnor_5.0	1	33,511,432 - 33,592,624 (-)	NCBI
Celera	1	28,120,766 - 28,174,109 (-)	NCBI

Sequence:

show sequence

GCTCCGGGGCAGCGTGTGGCTGCGAGGGACGCAGAGTCTAACGGAGCCATGCCCACGAACTTTACGGTGGTGCCGGTGGAGGCGCGCGCCGACGGCGCCGGGGACGAAGCTGCTGAGCGCACGGAAGA
ACCCGGGTCTCCCGAGAGCGCGGATCCTGCCTGCCCTACGCCGGGAGATGGAAACCCCAGGGAGAACAGCCCATTCATCAATAATGTGGAGGTGGAAAGAGAGAGCTACTTCGAGGGGAAGAACATGG
CGCTTTTTGAGGAAGAGATGGACAGCAACCCCATGGTATCATCACTGCTGAACAAGCTGGCCAACTATACCAACCTGAGCCAGGGTGTGGTAGAGCATGAGGAAGATGAGGACAGCCGGAGGCGGGAG
ATCAAGGCCCCACGCATGGGCACCTTCATCGGAGTCTACCTACCGTGCCTGCAGAACATCTTGGGTGTAATCCTTTTCCTGCGCCTGACCTGGATTGTGGGGGCGGCTGGCGTTCTGGAGTCCTTCCT
CATCGTGGCCATGTGCTGCACCTGTACAATGCTGACAGCCATCTCCATGAGTGCCATCGCTACCAACGGTGTGGTCCCAGCGGGAGGCTCATACTACATGATCTCCCGTTCGCTGGGGCCTGAGTTTG
GAGGGGCTGTTGGCCTCTGCTTCTACTTGGGCACAACGTTCGCAGGCGCCATGTACATCCTGGGAACCATCGAGATCTTCCTGACCTACATCTCTCCAAGTGCAGCCATCTTCCAGGCAGAGACAGCA
GACGGCGAGGCGGCCGCGCTGCTGAACAACATGCGTGTGTATGGCAGCTGCGCACTGGCGCTCATGGCCGTGGTGGTCTTCGTCGGAGTCAAATATGTCAACAAGCTGGCCCTGGTCTTCTTAGCCTG
TGTTGTGCTTTCTATCCTGGCCATCTATGCTGGTGTCATCAAGACAGCCTTCGCCCCACCTGACATCCCGGTCTGCCTTCTAGGGAACCGCACGCTGGCGAATCGCAACTTTGATACCTGTGCCAAAA
TGCAGGTTGTCAGCAATGGCACAGTCACCACCGCGCTCTGGCGCCTCTTCTGCAACGGCTCCAGCTTGGGTGCCTCCTGCGATGAGTACTTTGTGCAGAACAATGTCACTGAGATCCAGGGCATTCCT
GGTGTGGCCAGTGGTGTCTTCCTGGATAACCTGTGGAGCACGTATTCGGACAAGGGGGCATTTGTGGAAAAGAAGGGCGTGTCCTCGGTGCCTGTGTCCGAGGAGAGCCGGCCTGGTGGATTGCCATA
TGTCCTCACAGACATCATGACCTACTTCACCATGCTAGTCGGCATCTACTTCCCCTCCGTAACGGGGATCATGGCAGGATCCAACCGCTCCGGGGACCTCAAAGATGCCCAGAAGTCCATCCCAACAG
GGACCATTCTGGCCATTGTGACTACATCTTTCATTTATCTTTCCTGCATTGTGCTGTTTGGGGCCTGCATCGAGGGTGTAGTCTTGCGAGATAAGTTTGGGGAGGCCCTGCAAGGGAACTTGGTCATT
GGCATGCTGGCTTGGCCATCTCCCTGGGTCATCGTGATTGGCTCCTTCTTCTCCACCTGTGGTGCTGGCCTGCAGAGCCTAACTGGGGCACCCCGCCTGCTGCAGGCCATTGCACGCGACGGCATCAT
CCCCTTCCTGCAGGTGTTTGGCCATGGAAAGGCCAACGGGGAGCCCACGTGGGCCCTGCTGCTCACGGCCCTCATCTGTGAGACCGGCATCCTCATCGCCTCCCTGGACAGCGTGGCTCCCATCCTGT
CCATGTTCTTCCTCATGTGCTACATGTTCGTCAACCTGGCCTGTGCTGTTCAGACCCTGCTGCGCACACCCAACTGGCGTCCACGTTTCAAGTTCTACCACTGGACCCTCTCCTTCCTTGGGATGAGT
CTCTGCCTTGCGCTCATGTTCATCTGCTCCTGGTACTACGCCCTCTTCGCCATGCTCATCGCGGGCTGCATCTACAAGTACATCGAGTACCGAGGGGCTGAGAAGGAGTGGGGGGATGGCATCAGGGG
CCTGTCACTGAATGCTGCCCGCTATGCCCTGCTGCGTGTGGAACATGGGCCCCCACATACCAAGAACTGGAGGCCCCAGGTATTGGTGATGCTGAACCTGGACTCTGAGCAGTGTGTAAAGCACCCCC
GCCTGCTGTCCTTCACCTCTCAGCTGAAGGCTGGCAAGGGCCTGACCATCGTGGGATCTGTGCTGGAGGGCACCTACTTAGACAAGCATGTGGAGGCCCAGCGGGCTGAGGAGAATATCCGGTCTCTG
ATGAGTGCAGAGAAGATGAAAGGCTTCTGCCAGCTGGTGGTGTCGTCCAACCTGCGAGACGGTGCATCCCACTTGATCCAGTCAGCTGGCCTTGGTGGCATGAAGCACAACACTGTCCTCATGGCCTG
GCCAGAGGCTTGGAAGCAGGCAGATAACCCTTTCTCCTGGAAGAACTTTGTGGACACTGTCCGTGACACTACAGCAGCACATCAGGCACTGTTGGTGGCCAAGAACATCGACTTGTTCCCGCAGAACC
AGGAGCGCTTCAGCGACGGCAACATCGATGTGTGGTGGATCGTGCACGATGGGGGGATGCTCATGCTTCTGCCGTTCCTGCTGCGCCAGCACAAGGTGTGGCGAAAGTGCCGGATGCGCATCTTCACG
GTCGCCCAGGTGGACGATAACAGCATCCAGATGAAGAAGGACCTGCAGATGTTCCTGTACCATCTCAGGATCAGCGCCGAGGTGGAGGTGGTAGAGATGGTTGAAAATGACATTTCTGCATTCACCTA
TGAGAAGACGCTAATGATGGAGCAGAGGTCACAGATGCTGAAACAGATGCAGTTGTCAAAGAATGAGCGGGAGAGAGAGGCCCAGCTGATTCACGACAGGAACACTGCATCCCACACCGTAGCAACGG
CTAGAACTGAAGCCCCACCAACACCTGACAAAGTGCAGATGACATGGACGAAAGAGAAACTCATTGCAGAGAAACACAGGAACAAGGACACCGGCACATCAGGCTTCAAAGACCTTTTCAGCCTAAAG
CCGGACCAGTCCAACGTCAGAAGGATGCATACTGCTGTGAAGCTCAATGGTGTGGTTCTCAACAAGTCCCAGGATGCTCAACTCGTCCTGCTGAATATGCCAGGCCCCCCAAAAAGTCGGCAGGGCGA
CGAGAACTACATGGAATTTCTTGAGGTCTTGACCGAAGGGCTGAACAGGGTCCTCCTGGTCAGGGGTGGTGGCCGGGAAGTCATCACCATCTACTCCTAACACCTGAAGCCTGGACACACATGGATGG
GGTCAGGACTTCGCGAGCTGCCTGTGACCAGGCTGGGGCTCACCAGGTGCTGCTGACTGATGGCCTACCCTAGCACCTGTTGCCTGGCCAACCAAGATGTTGCAGTGATCCTGGTCACCCTGACACAC
ATGGCTTCCCACAGACATAATACTCCGTAGGCTTCCTCCAAGCAGAGGATGCTACATGGGGAGTATCTAGAGCTGTTCTGACAGGAATGGCTCCTTAACATTGTCGTGGGCAACGGTAGGTATACCCA
GGGGATCTGGGGCAGCTCTGGCGCCTCTGTACCTTTCACGAACCTGACAGATGAACCAGAACACGTGAACAAGCACACAGTTCCTTGGGGCTAGAATGTCACTGAGCGGTTCTCCATTGGCTTCTGCC
TTCTTCGTTCCTTGGAGCATCCCTGATGTGCTTTCTGTACAGTAGGCACACTGAGGACTGTTCACCCTCACGCACACCTCACCTCCTTATTTCCTCCCCGCTCTCCTCAGACACGGCTCAGGGTACCA
CTGGAAAGTGACATAGTGTTTACAGGATAGGAGTGGGTCACCATTAGAGCCGGTGGTGCCTGCCAGCTCTGTTCCCATCTGAGTTGATGCCCTAGGAGCTCCTGCAGAGAGAACCTTTGTTCTGCAGG
GCTCTCTGCAGTGAGCCCGCGTTCTCTTCTCACGGGAACTCAGTCACTTTACTTCATAAGCACTGAGCTGGGACCTCAAGCGGGTGACTACCGGGAGCCACAGTGTGACAAACAGCAGGAACACTGAG
AACTCTGCACATAGTCCATGATGACAGCAAGGCACCTTCCAGAGTGTGAACCATGCACACAGCTTCACATATGACATGCCGTCCCATCCCTCACCCTCCTGGAGAGAACAGCCAGGCCCAGCCCAGTA
CCCTCGGCATCGGCAGCCACAGCCCTGGGTCTTTCTGGCTGAGTCTCTTGTCTCCTGCTGTGGAGCCTTGCTCAGCCGGGGCCATGGGCGCCTCTGCACTTTCTAAGGAGCTGACAGATGATTTGCAC
TTTACCCTTGGGCATTCTGTTCTGTAGGTCATGGTTTGTTCACAGGCTGTGGGCAACAGCAGTGATCCGTTCCTCACATTGTGTGTGGCATATTTATTTATTTAACCCTCCCTGGGGAAGCTTGATAG
AGATAGCTTCTGTGTGGATGCCCCGTGCTGCCAGGCTCTGGGCATCTCTGGCTTCCTCCGAGAGAATCAACCCCGTCCACACTCACGACGTTCTGGTTAGGGTAGAAGCCAAGTTTGCACCTGCACAG
TTTCTTCAGACTTTGTTAGGCAGCCAGAGGTAGGCTTGCCAAGTAACTGCTGCCCGGTGTGTGTCCCCATCAGGGTAGTGATTTCCACACCTGCTTTTGACTCAGCACTGGACTTGGCTCAGACTCCT
GAGCCCTCGATGTCTAGAGCAGAGCAGGTGGGGCGCTGCTCCCAGCTGTCAGGAATGCCTTGGGCAGGTGGCCCTTTCAGGTTCTGGGTCACTGCTTACAAGAGCTGCCTGTCAAGAGTGTCCAGCCT
CCTTATCTCGCAGACTCCGTGTTCCTGGTAACTGTGGCCATTCAGATCAGTTTCATGTTTTCCTTTTTATAGGCTTTTGCCTTTGTATGACTTTGTTAGTAGAAGAGTAAAGTTCTATAAAATATAAA
TGTTTAAGGAA

hide sequence

RefSeq Acc Id:

XM_006227789 ⟹ XP_006227851

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	31,301,243 - 31,382,825 (-)	NCBI
mRatBN7.2	1	29,472,692 - 29,554,245 (-)	NCBI
Rnor_6.0	1	32,086,755 - 32,167,950 (-)	NCBI
Rnor_5.0	1	33,511,432 - 33,592,624 (-)	NCBI

Sequence:

show sequence

CCGCTCCCCGAGACCCACGGTCAGCACCGGCAGACCTTCGCATCCAGCAGTCATCGCGGCGCCT
GGCGTTCCGACGCCAACATGTCCCAGCGCTTCGTGGTGATCCCAGCACAGAGCGGGACGGGGGACGCGGGACCCAGGGCAGAAGGTGGCAGCGGCGGCAGCCAGCGCCTGTGCTCGGATCCCGACCCC
GACCCCGACCCTGACCCCGACCCCGATCCCAGCCTGGCGGCCGCTCTGAAAACACAAGAAGTAGATGCGCTGCCCATTCTGCGCTACTGCCGCGAGCCCAGCCGCTATGGAGATGGAAACCCCAGGGA
GAACAGCCCATTCATCAATAATGTGGAGGTGGAAAGAGAGAGCTACTTCGAGGGGAAGAACATGGCGCTTTTTGAGGAAGAGATGGACAGCAACCCCATGGTATCATCACTGCTGAACAAGCTGGCCA
ACTATACCAACCTGAGCCAGGGTGTGGTAGAGCATGAGGAAGATGAGGACAGCCGGAGGCGGGAGATCAAGGCCCCACGCATGGGCACCTTCATCGGAGTCTACCTACCGTGCCTGCAGAACATCTTG
GGTGTAATCCTTTTCCTGCGCCTGACCTGGATTGTGGGGGCGGCTGGCGTTCTGGAGTCCTTCCTCATCGTGGCCATGTGCTGCACCTGTACAATGCTGACAGCCATCTCCATGAGTGCCATCGCTAC
CAACGGTGTGGTCCCAGCGGGAGGCTCATACTACATGATCTCCCGTTCGCTGGGGCCTGAGTTTGGAGGGGCTGTTGGCCTCTGCTTCTACTTGGGCACAACGTTCGCAGGCGCCATGTACATCCTGG
GAACCATCGAGATCTTCCTGACCTACATCTCTCCAAGTGCAGCCATCTTCCAGGCAGAGACAGCAGACGGCGAGGCGGCCGCGCTGCTGAACAACATGCGTGTGTATGGCAGCTGCGCACTGGCGCTC
ATGGCCGTGGTGGTCTTCGTCGGAGTCAAATATGTCAACAAGCTGGCCCTGGTCTTCTTAGCCTGTGTTGTGCTTTCTATCCTGGCCATCTATGCTGGTGTCATCAAGACAGCCTTCGCCCCACCTGA
CATCCCGGTCTGCCTTCTAGGGAACCGCACGCTGGCGAATCGCAACTTTGATACCTGTGCCAAAATGCAGGTTGTCAGCAATGGCACAGTCACCACCGCGCTCTGGCGCCTCTTCTGCAACGGCTCCA
GCTTGGGTGCCTCCTGCGATGAGTACTTTGTGCAGAACAATGTCACTGAGATCCAGGGCATTCCTGGTGTGGCCAGTGGTGTCTTCCTGGATAACCTGTGGAGCACGTATTCGGACAAGGGGGCATTT
GTGGAAAAGAAGGGCGTGTCCTCGGTGCCTGTGTCCGAGGAGAGCCGGCCTGGTGGATTGCCATATGTCCTCACAGACATCATGACCTACTTCACCATGCTAGTCGGCATCTACTTCCCCTCCGTAAC
GGGGATCATGGCAGGATCCAACCGCTCCGGGGACCTCAAAGATGCCCAGAAGTCCATCCCAACAGGGACCATTCTGGCCATTGTGACTACATCTTTCATTTATCTTTCCTGCATTGTGCTGTTTGGGG
CCTGCATCGAGGGTGTAGTCTTGCGAGATAAGTTTGGGGAGGCCCTGCAAGGGAACTTGGTCATTGGCATGCTGGCTTGGCCATCTCCCTGGGTCATCGTGATTGGCTCCTTCTTCTCCACCTGTGGT
GCTGGCCTGCAGAGCCTAACTGGGGCACCCCGCCTGCTGCAGGCCATTGCACGCGACGGCATCATCCCCTTCCTGCAGGTGTTTGGCCATGGAAAGGCCAACGGGGAGCCCACGTGGGCCCTGCTGCT
CACGGCCCTCATCTGTGAGACCGGCATCCTCATCGCCTCCCTGGACAGCGTGGCTCCCATCCTGTCCATGTTCTTCCTCATGTGCTACATGTTCGTCAACCTGGCCTGTGCTGTTCAGACCCTGCTGC
GCACACCCAACTGGCGTCCACGTTTCAAGTTCTACCACTGGACCCTCTCCTTCCTTGGGATGAGTCTCTGCCTTGCGCTCATGTTCATCTGCTCCTGGTACTACGCCCTCTTCGCCATGCTCATCGCG
GGCTGCATCTACAAGTACATCGAGTACCGAGGGGCTGAGAAGGAGTGGGGGGATGGCATCAGGGGCCTGTCACTGAATGCTGCCCGCTATGCCCTGCTGCGTGTGGAACATGGGCCCCCACATACCAA
GAACTGGAGGCCCCAGGTATTGGTGATGCTGAACCTGGACTCTGAGCAGTGTGTAAAGCACCCCCGCCTGCTGTCCTTCACCTCTCAGCTGAAGGCTGGCAAGGGCCTGACCATCGTGGGATCTGTGC
TGGAGGGCACCTACTTAGACAAGCATGTGGAGGCCCAGCGGGCTGAGGAGAATATCCGGTCTCTGATGAGTGCAGAGAAGATGAAAGGCTTCTGCCAGCTGGTGGTGTCGTCCAACCTGCGAGACGGT
GCATCCCACTTGATCCAGTCAGCTGGCCTTGGTGGCATGAAGCACAACACTGTCCTCATGGCCTGGCCAGAGGCTTGGAAGCAGGCAGATAACCCTTTCTCCTGGAAGAACTTTGTGGACACTGTCCG
TGACACTACAGCAGCACATCAGGCACTGTTGGTGGCCAAGAACATCGACTTGTTCCCGCAGAACCAGGAGCGCTTCAGCGACGGCAACATCGATGTGTGGTGGATCGTGCACGATGGGGGGATGCTCA
TGCTTCTGCCGTTCCTGCTGCGCCAGCACAAGGTGTGGCGAAAGTGCCGGATGCGCATCTTCACGGTCGCCCAGGTGGACGATAACAGCATCCAGATGAAGAAGGACCTGCAGATGTTCCTGTACCAT
CTCAGGATCAGCGCCGAGGTGGAGGTGGTAGAGATGGTTGAAAATGACATTTCTGCATTCACCTATGAGAAGACGCTAATGATGGAGCAGAGGTCACAGATGCTGAAACAGATGCAGTTGTCAAAGAA
TGAGCGGGAGAGAGAGGCCCAGCTGATTCACGACAGGAACACTGCATCCCACACCGTAGCAACGGCTAGAACTGAAGCCCCACCAACACCTGACAAAGTGCAGATGACATGGACGAAAGAGAAACTCA
TTGCAGAGAAACACAGGAACAAGGACACCGGCACATCAGGCTTCAAAGACCTTTTCAGCCTAAAGCCGGACCAGTCCAACGTCAGAAGGATGCATACTGCTGTGAAGCTCAATGGTGTGGTTCTCAAC
AAGTCCCAGGATGCTCAACTCGTCCTGCTGAATATGCCAGGCCCCCCAAAAAGTCGGCAGGGCGACGAGAACTACATGGAATTTCTTGAGGTCTTGACCGAAGGGCTGAACAGGGTCCTCCTGGTCAG
GGGTGGTGGCCGGGAAGTCATCACCATCTACTCCTAACACCTGAAGCCTGGACACACATGGATGGGGTCAGGACTTCGCGAGCTGCCTGTGACCAGGCTGGGGCTCACCAGGTGCTGCTGACTGATGG
CCTACCCTAGCACCTGTTGCCTGGCCAACCAAGATGTTGCAGTGATCCTGGTCACCCTGACACACATGGCTTCCCACAGACATAATACTCCGTAGGCTTCCTCCAAGCAGAGGATGCTACATGGGGAG
TATCTAGAGCTGTTCTGACAGGAATGGCTCCTTAACATTGTCGTGGGCAACGGTAGGTATACCCAGGGGATCTGGGGCAGCTCTGGCGCCTCTGTACCTTTCACGAACCTGACAGATGAACCAGAACA
CGTGAACAAGCACACAGTTCCTTGGGGCTAGAATGTCACTGAGCGGTTCTCCATTGGCTTCTGCCTTCTTCGTTCCTTGGAGCATCCCTGATGTGCTTTCTGTACAGTAGGCACACTGAGGACTGTTC
ACCCTCACGCACACCTCACCTCCTTATTTCCTCCCCGCTCTCCTCAGACACGGCTCAGGGTACCACTGGAAAGTGACATAGTGTTTACAGGATAGGAGTGGGTCACCATTAGAGCCGGTGGTGCCTGC
CAGCTCTGTTCCCATCTGAGTTGATGCCCTAGGAGCTCCTGCAGAGAGAACCTTTGTTCTGCAGGGCTCTCTGCAGTGAGCCCGCGTTCTCTTCTCACGGGAACTCAGTCACTTTACTTCATAAGCAC
TGAGCTGGGACCTCAAGCGGGTGACTACCGGGAGCCACAGTGTGACAAACAGCAGGAACACTGAGAACTCTGCACATAGTCCATGATGACAGCAAGGCACCTTCCAGAGTGTGAACCATGCACACAGC
TTCACATATGACATGCCGTCCCATCCCTCACCCTCCTGGAGAGAACAGCCAGGCCCAGCCCAGTACCCTCGGCATCGGCAGCCACAGCCCTGGGTCTTTCTGGCTGAGTCTCTTGTCTCCTGCTGTGG
AGCCTTGCTCAGCCGGGGCCATGGGCGCCTCTGCACTTTCTAAGGAGCTGACAGATGATTTGCACTTTACCCTTGGGCATTCTGTTCTGTAGGTCATGGTTTGTTCACAGGCTGTGGGCAACAGCAGT
GATCCGTTCCTCACATTGTGTGTGGCATATTTATTTATTTAACCCTCCCTGGGGAAGCTTGATAGAGATAGCTTCTGTGTGGATGCCCCGTGCTGCCAGGCTCTGGGCATCTCTGGCTTCCTCCGAGA
GAATCAACCCCGTCCACACTCACGACGTTCTGGTTAGGGTAGAAGCCAAGTTTGCACCTGCACAGTTTCTTCAGACTTTGTTAGGCAGCCAGAGGTAGGCTTGCCAAGTAACTGCTGCCCGGTGTGTG
TCCCCATCAGGGTAGTGATTTCCACACCTGCTTTTGACTCAGCACTGGACTTGGCTCAGACTCCTGAGCCCTCGATGTCTAGAGCAGAGCAGGTGGGGCGCTGCTCCCAGCTGTCAGGAATGCCTTGG
GCAGGTGGCCCTTTCAGGTTCTGGGTCACTGCTTACAAGAGCTGCCTGTCAAGAGTGTCCAGCCTCCTTATCTCGCAGACTCCGTGTTCCTGGTAACTGTGGCCATTCAGATCAGTTTCATGTTTTCC
TTTTTATAGGCTTTTGCCTTTGTATGACTTTGTTAGTAGAAGAGTAAAGTTCTATAAAATATAAATGTTTAAGGAA

hide sequence

RefSeq Acc Id:

XM_063288386 ⟹ XP_063144456

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	31,301,243 - 31,382,805 (-)	NCBI

RefSeq Acc Id:

XM_063288392 ⟹ XP_063144462

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	31,301,243 - 31,354,918 (-)	NCBI


Protein RefSeqs	NP_001013162	(Get FASTA)	NCBI Sequence Viewer
	XP_006227851	(Get FASTA)	NCBI Sequence Viewer
	XP_063144456	(Get FASTA)	NCBI Sequence Viewer
	XP_063144462	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH86339	(Get FASTA)	NCBI Sequence Viewer
	AAQ93479	(Get FASTA)	NCBI Sequence Viewer
	AAQ93480	(Get FASTA)	NCBI Sequence Viewer
	AAQ93481	(Get FASTA)	NCBI Sequence Viewer
	AAR10805	(Get FASTA)	NCBI Sequence Viewer
	EDL87666	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000074714
	ENSRNOP00000088698
GenBank Protein	Q5RK27	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001013162 ⟸ NM_001013144

- UniProtKB:

Q6TUA1 (UniProtKB/Swiss-Prot), Q6T7Y5 (UniProtKB/Swiss-Prot), Q6TUA2 (UniProtKB/Swiss-Prot), Q5RK27 (UniProtKB/Swiss-Prot), A6JUW3 (UniProtKB/TrEMBL), A0A8L2QBZ1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPTNFTVVPVEARADGAGDEAAERTEEPGSPESADPACPTPGDGNPRENSPFINNVEVERESYFEGKNMALFEEEMDSNPMVSSLLNKLANYTNLSQGVVEHEEDEDSRRREIKAPRMGTFIGVYLPC
LQNILGVILFLRLTWIVGAAGVLESFLIVAMCCTCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEIFLTYISPSAAIFQAETADGEAAALLNNMRVYGS
CALALMAVVVFVGVKYVNKLALVFLACVVLSILAIYAGVIKTAFAPPDIPVCLLGNRTLANRNFDTCAKMQVVSNGTVTTALWRLFCNGSSLGASCDEYFVQNNVTEIQGIPGVASGVFLDNLWSTYS
DKGAFVEKKGVSSVPVSEESRPGGLPYVLTDIMTYFTMLVGIYFPSVTGIMAGSNRSGDLKDAQKSIPTGTILAIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSF
FSTCGAGLQSLTGAPRLLQAIARDGIIPFLQVFGHGKANGEPTWALLLTALICETGILIASLDSVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMSLCLALMFICSWYYALF
AMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALLRVEHGPPHTKNWRPQVLVMLNLDSEQCVKHPRLLSFTSQLKAGKGLTIVGSVLEGTYLDKHVEAQRAEENIRSLMSAEKMKGFCQLVVSS
NLRDGASHLIQSAGLGGMKHNTVLMAWPEAWKQADNPFSWKNFVDTVRDTTAAHQALLVAKNIDLFPQNQERFSDGNIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQVDDNSIQMKKDLQ
MFLYHLRISAEVEVVEMVENDISAFTYEKTLMMEQRSQMLKQMQLSKNEREREAQLIHDRNTASHTVATARTEAPPTPDKVQMTWTKEKLIAEKHRNKDTGTSGFKDLFSLKPDQSNVRRMHTAVKLN
GVVLNKSQDAQLVLLNMPGPPKSRQGDENYMEFLEVLTEGLNRVLLVRGGGREVITIYS

hide sequence

RefSeq Acc Id:	XP_006227851 ⟸ XM_006227789
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2K8S1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSQRFVVIPAQSGTGDAGPRAEGGSGGSQRLCSDPDPDPDPDPDPDPSLAAALKTQEVDALPIL RYCREPSRYGDGNPRENSPFINNVEVERESYFEGKNMALFEEEMDSNPMVSSLLNKLANYTNLSQGVVEHEEDEDSRRREIKAPRMGTFIGVYLPCLQNILGVILFLRLTWIVGAAGVLESFLIVAMC CTCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEIFLTYISPSAAIFQAETADGEAAALLNNMRVYGSCALALMAVVVFVGVKYVNKLALVFLACVVLSI LAIYAGVIKTAFAPPDIPVCLLGNRTLANRNFDTCAKMQVVSNGTVTTALWRLFCNGSSLGASCDEYFVQNNVTEIQGIPGVASGVFLDNLWSTYSDKGAFVEKKGVSSVPVSEESRPGGLPYVLTDI MTYFTMLVGIYFPSVTGIMAGSNRSGDLKDAQKSIPTGTILAIVTTSFIYLSCIVLFGACIEGVVLRDKFGEALQGNLVIGMLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIARDGIIPFLQV FGHGKANGEPTWALLLTALICETGILIASLDSVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMSLCLALMFICSWYYALFAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNA ARYALLRVEHGPPHTKNWRPQVLVMLNLDSEQCVKHPRLLSFTSQLKAGKGLTIVGSVLEGTYLDKHVEAQRAEENIRSLMSAEKMKGFCQLVVSSNLRDGASHLIQSAGLGGMKHNTVLMAWPEAWK QADNPFSWKNFVDTVRDTTAAHQALLVAKNIDLFPQNQERFSDGNIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQVDDNSIQMKKDLQMFLYHLRISAEVEVVEMVENDISAFTYEKTLM MEQRSQMLKQMQLSKNEREREAQLIHDRNTASHTVATARTEAPPTPDKVQMTWTKEKLIAEKHRNKDTGTSGFKDLFSLKPDQSNVRRMHTAVKLNGVVLNKSQDAQLVLLNMPGPPKSRQGDENYME FLEVLTEGLNRVLLVRGGGREVITIYS hide sequence

Ensembl Acc Id:

ENSRNOP00000074714 ⟸ ENSRNOT00000078039

Ensembl Acc Id:

ENSRNOP00000071618 ⟸ ENSRNOT00000081339

Ensembl Acc Id:

ENSRNOP00000022635 ⟸ ENSRNOT00000022635

Protein Domains

Amino acid permease/ SLC12A SLC12A transporter C-terminal

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5RK27-F1-model_v2	AlphaFold	Q5RK27	1-1083	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13689565

Promoter ID:

EPDNEW_R90

Type:

initiation region

Name:

Slc12a7_1

Description:

solute carrier family 12 member 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	32,140,151 - 32,140,211	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-61930	BioCyc
Ensembl Genes	ENSRNOG00000016372	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000078039	ENTREZGENE
	ENSRNOT00000112535	ENTREZGENE
Gene3D-CATH	Amino acid/polyamine transporter I	UniProtKB/Swiss-Prot
InterPro	AA-permease/SLC12A_dom	UniProtKB/Swiss-Prot
	KCL_cotranspt	UniProtKB/Swiss-Prot
	SLC12_C	UniProtKB/Swiss-Prot
	SLC12A_fam	UniProtKB/Swiss-Prot
KEGG Report	rno:308069	UniProtKB/Swiss-Prot
NCBI Gene	308069	ENTREZGENE
PANTHER	PTHR11827	UniProtKB/Swiss-Prot
	PTHR11827:SF47	UniProtKB/Swiss-Prot
Pfam	AA_permease	UniProtKB/Swiss-Prot
	SLC12	UniProtKB/Swiss-Prot
PhenoGen	Slc12a7	PhenoGen
PRINTS	KCLTRNSPORT	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000016372	RatGTEx
UniProt	A0A0G2K0X6_RAT	UniProtKB/TrEMBL
	A0A0G2K8S1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A5L8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2QBZ1	ENTREZGENE, UniProtKB/TrEMBL
	A6JUW3	ENTREZGENE, UniProtKB/TrEMBL
	Q5RK27	ENTREZGENE
	Q6T7Y5	ENTREZGENE
	Q6TUA1	ENTREZGENE
	Q6TUA2	ENTREZGENE
	S12A7_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	Q6T7Y5	UniProtKB/Swiss-Prot
	Q6TUA1	UniProtKB/Swiss-Prot
	Q6TUA2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-25	Slc12a7	solute carrier family 12 member 7	Slc12a7	solute carrier family 12 (potassium/chloride transporter), member 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-02	Slc12a7	solute carrier family 12 (potassium/chloride transporter), member 7	Slc12a7	solute carrier family 12 (potassium/chloride transporters), member 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-19	Slc12a7	solute carrier family 12 (potassium/chloride transporters), member 7	Slc12a7	solute carrier family 12, member 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Slc12a7	solute carrier family 12, member 7	Slc12a7	solute carrier family 12 (potassium/chloride transporters), member 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-11-17	Slc12a7	solute carrier family 12 (potassium/chloride transporters), member 7			Symbol and Name updated	1299863	APPROVED
2005-07-29	LOC308069	K-Cl cotransporter KCC4			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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