Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Klhdc8b | Rat | Hodgkin's lymphoma | | ISO | KLHDC8B (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Klhdc8b | Rat | Hodgkin's lymphoma | | ISO | KLHDC8B (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
3. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
4. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
5. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
Klhdc8b (Rattus norvegicus - Norway rat) |
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KLHDC8B (Homo sapiens - human) |
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Klhdc8b (Mus musculus - house mouse) |
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Klhdc8b (Chinchilla lanigera - long-tailed chinchilla) |
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KLHDC8B (Pan paniscus - bonobo/pygmy chimpanzee) |
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KLHDC8B (Canis lupus familiaris - dog) |
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Klhdc8b (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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KLHDC8B (Sus scrofa - pig) |
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KLHDC8B (Chlorocebus sabaeus - green monkey) |
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Klhdc8b (Heterocephalus glaber - naked mole-rat) |
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Variants in Klhdc8b
18 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH140155 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_001007685 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_039081332 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063265323 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC128721 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC083777 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000008 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000071381 ⟹ ENSRNOP00000066316 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000101706 ⟹ ENSRNOP00000095128 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000105799 ⟹ ENSRNOP00000090705 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001007685 ⟹ NP_001007686 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039081332 ⟹ XP_038937260 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063265323 ⟹ XP_063121393 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001007686 | (Get FASTA) | NCBI Sequence Viewer |
XP_038937260 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063121393 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH83777 | (Get FASTA) | NCBI Sequence Viewer |
Ensembl Protein | ENSRNOP00000066316.2 | ||
ENSRNOP00000090705.1 | |||
ENSRNOP00000095128.1 | |||
ENSRNOP00055018807 | |||
ENSRNOP00060036893 | |||
ENSRNOP00065007514 | |||
GenBank Protein | Q5XIA9 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_001007686 ⟸ NM_001007685 |
- UniProtKB: | Q5XIA9 (UniProtKB/Swiss-Prot), A6I356 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000066316 ⟸ ENSRNOT00000071381 |
RefSeq Acc Id: | XP_038937260 ⟸ XM_039081332 |
- Peptide Label: | isoform X2 |
Ensembl Acc Id: | ENSRNOP00000095128 ⟸ ENSRNOT00000101706 |
Ensembl Acc Id: | ENSRNOP00000090705 ⟸ ENSRNOT00000105799 |
RefSeq Acc Id: | XP_063121393 ⟸ XM_063265323 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6B214 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q5XIA9-F1-model_v2 | AlphaFold | Q5XIA9 | 1-354 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13696301 | ||||||||
Promoter ID: | EPDNEW_R6825 | ||||||||
Type: | single initiation site | ||||||||
Name: | Klhdc8b_1 | ||||||||
Description: | kelch domain containing 8B | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1359445 | AgrOrtholog |
BioCyc Gene | G2FUF-29141 | BioCyc |
Ensembl Genes | ENSRNOG00000047867 | Ensembl, UniProtKB/TrEMBL |
ENSRNOG00055013515 | UniProtKB/Swiss-Prot | |
ENSRNOG00060025740 | UniProtKB/Swiss-Prot | |
ENSRNOG00065006652 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000071381.3 | UniProtKB/TrEMBL |
ENSRNOT00000101706.1 | UniProtKB/TrEMBL | |
ENSRNOT00000105799.1 | UniProtKB/TrEMBL | |
ENSRNOT00055023169 | UniProtKB/Swiss-Prot | |
ENSRNOT00060044532 | UniProtKB/Swiss-Prot | |
ENSRNOT00065010282 | UniProtKB/Swiss-Prot | |
Gene3D-CATH | 2.120.10.80 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
IMAGE_CLONE | IMAGE:7193594 | IMAGE-MGC_LOAD |
InterPro | Gal_Oxase/kelch_b-propeller | UniProtKB/TrEMBL |
Kelch-typ_b-propeller | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Kelch_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Kelch_domain_containing_8 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:306589 | UniProtKB/Swiss-Prot |
MGC_CLONE | MGC:94736 | IMAGE-MGC_LOAD |
NCBI Gene | 306589 | ENTREZGENE |
PANTHER | KELCH DOMAIN-CONTAINING PROTEIN 8B | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RING-TYPE DOMAIN-CONTAINING PROTEIN | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | Kelch_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Kelch_6 | UniProtKB/TrEMBL | |
PhenoGen | Klhdc8b | PhenoGen |
RatGTEx | ENSRNOG00000047867 | RatGTEx |
ENSRNOG00055013515 | RatGTEx | |
ENSRNOG00060025740 | RatGTEx | |
ENSRNOG00065006652 | RatGTEx | |
SMART | Kelch | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | SSF117281 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF50965 | UniProtKB/TrEMBL | |
UniProt | A0A8I6AAM5_RAT | UniProtKB/TrEMBL |
A0A8I6B214 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8L2QZF1_RAT | UniProtKB/TrEMBL | |
A6I356 | ENTREZGENE, UniProtKB/TrEMBL | |
KLD8B_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2008-03-06 | Klhdc8b | kelch domain containing 8B | MGC94736 | similar to hypothetical protein MGC35097 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-07-29 | MGC94736 | similar to hypothetical protein MGC35097 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |