Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Desi2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Desi2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of DESI2 mRNA | CTD | PMID:22206623 | Desi2 | Rat | 17beta-estradiol | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | Estradiol results in increased expression of DESI2 mRNA | CTD | PMID:39298647 | Desi2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Desi2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DESI2 mRNA | CTD | PMID:21570461 | Desi2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DESI2 mRNA | CTD | PMID:34747641 | Desi2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of DESI2 mRNA | CTD | PMID:21346803 | Desi2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of DESI2 mRNA | CTD | PMID:39298647 | Desi2 | Rat | all-trans-retinoic acid | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DESI2 mRNA | CTD | PMID:16054129|PMID:21934132 | Desi2 | Rat | antirheumatic drug | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of DESI2 mRNA | CTD | PMID:24449571 | Desi2 | Rat | arsenous acid | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of DESI2 mRNA | CTD | PMID:20458559|PMID:22521957 | Desi2 | Rat | benzene | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Benzene results in increased expression of DESI2 mRNA | CTD | PMID:15929907 | Desi2 | Rat | benzo[a]pyrene | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of DESI2 mRNA | CTD | PMID:22228805 | Desi2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DESI2 mRNA | CTD | PMID:20018196 | Desi2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DESI2 mRNA | CTD | PMID:25181051 | Desi2 | Rat | bisphenol A | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of DESI2 mRNA | CTD | PMID:40036665 | Desi2 | Rat | cadmium atom | multiple interactions | ISO | Desi2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DESI2 more ... | CTD | PMID:37236586 | Desi2 | Rat | cadmium dichloride | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of DESI2 mRNA | CTD | PMID:26472689 | Desi2 | Rat | cadmium dichloride | multiple interactions | ISO | Desi2 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DESI2 more ... | CTD | PMID:37236586 | Desi2 | Rat | carbon nanotube | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | Nanotubes, Carbon results in increased expression of DESI2 mRNA | CTD | PMID:25554681|PMID:25620056 | Desi2 | Rat | cobalt dichloride | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of DESI2 mRNA | CTD | PMID:19376846 | Desi2 | Rat | copper(II) sulfate | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of DESI2 mRNA | CTD | PMID:19549813 | Desi2 | Rat | coumarin | increases phosphorylation | ISO | DESI2 (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of DESI2 protein | CTD | PMID:35688186 | Desi2 | Rat | coumestrol | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of DESI2 mRNA | CTD | PMID:19167446 | Desi2 | Rat | crocidolite asbestos | decreases expression | ISO | Desi2 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of DESI2 mRNA | CTD | PMID:29279043 | Desi2 | Rat | cyclosporin A | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DESI2 mRNA | CTD | PMID:20106945 | Desi2 | Rat | diarsenic trioxide | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of DESI2 mRNA | CTD | PMID:20458559|PMID:22521957 | Desi2 | Rat | dibenz[a,h]anthracene | decreases expression | ISO | Desi2 (Mus musculus) | 6480464 | 1,2,5,6-dibenzanthracene results in decreased expression of DESI2 mRNA | CTD | PMID:26377693 | Desi2 | Rat | diethylstilbestrol | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of DESI2 mRNA | CTD | PMID:36621641 | Desi2 | Rat | dorsomorphin | multiple interactions | ISO | DESI2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Desi2 | Rat | elemental selenium | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Selenium results in decreased expression of DESI2 mRNA | CTD | PMID:19244175 | Desi2 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of DESI2 mRNA | CTD | PMID:24136188 | Desi2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of DESI2 mRNA | CTD | PMID:24136188 | Desi2 | Rat | furan | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | furan results in increased expression of DESI2 mRNA | CTD | PMID:24183702 | Desi2 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of DESI2 mRNA | CTD | PMID:24136188 | Desi2 | Rat | inulin | multiple interactions | ISO | Desi2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of DESI2 mRNA | CTD | PMID:36331819 | Desi2 | Rat | irinotecan | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Irinotecan analog results in decreased expression of DESI2 mRNA | CTD | PMID:18927307 | Desi2 | Rat | ketoconazole | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Ketoconazole results in decreased expression of DESI2 mRNA | CTD | PMID:36621641 | Desi2 | Rat | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of DESI2 mRNA | CTD | PMID:24136188 | Desi2 | Rat | menadione | affects expression | ISO | DESI2 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of DESI2 mRNA | CTD | PMID:20044591 | Desi2 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of DESI2 mRNA | CTD | PMID:24136188 | Desi2 | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of DESI2 mRNA | CTD | PMID:24136188 | Desi2 | Rat | paracetamol | affects expression | ISO | Desi2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of DESI2 mRNA | CTD | PMID:17562736 | Desi2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of DESI2 mRNA | CTD | PMID:33387578 | Desi2 | Rat | paracetamol | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of DESI2 mRNA | CTD | PMID:21420995|PMID:29067470 | Desi2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Desi2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of DESI2 mRNA | CTD | PMID:36331819 | Desi2 | Rat | phenobarbital | decreases expression | ISO | Desi2 (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of DESI2 mRNA | CTD | PMID:19270015 | Desi2 | Rat | phenobarbital | affects expression | ISO | Desi2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of DESI2 mRNA | CTD | PMID:23091169 | Desi2 | Rat | pirinixic acid | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DESI2 mRNA | CTD | PMID:23811191 | Desi2 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of DESI2 mRNA | CTD | PMID:28903501 | Desi2 | Rat | propiconazole | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | propiconazole results in increased expression of DESI2 mRNA | CTD | PMID:21278054 | Desi2 | Rat | raloxifene | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | Raloxifene Hydrochloride results in increased expression of DESI2 mRNA | CTD | PMID:33269387 | Desi2 | Rat | Salinomycin | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | salinomycin results in decreased expression of DESI2 mRNA | CTD | PMID:19682730 | Desi2 | Rat | SB 431542 | multiple interactions | ISO | DESI2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Desi2 | Rat | selenium atom | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Selenium results in decreased expression of DESI2 mRNA | CTD | PMID:19244175 | Desi2 | Rat | silicon dioxide | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of DESI2 mRNA | CTD | PMID:22300531|PMID:25351596 | Desi2 | Rat | sodium arsenite | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of DESI2 mRNA | CTD | PMID:38568856 | Desi2 | Rat | sodium arsenite | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of DESI2 mRNA | CTD | PMID:39719251 | Desi2 | Rat | sunitinib | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of DESI2 mRNA | CTD | PMID:31533062 | Desi2 | Rat | testosterone enanthate | affects expression | ISO | DESI2 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of DESI2 mRNA | CTD | PMID:17440010 | Desi2 | Rat | tetrachloromethane | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of DESI2 mRNA | CTD | PMID:31919559 | Desi2 | Rat | titanium dioxide | decreases expression | ISO | Desi2 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of DESI2 mRNA | CTD | PMID:29264374 | Desi2 | Rat | trichostatin A | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of DESI2 mRNA | CTD | PMID:26272509 | Desi2 | Rat | trichostatin A | multiple interactions | ISO | DESI2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... | CTD | PMID:27188386 | Desi2 | Rat | trimellitic anhydride | increases expression | ISO | Desi2 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of DESI2 mRNA | CTD | PMID:19042947 | Desi2 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of DESI2 mRNA | CTD | PMID:30589522 | Desi2 | Rat | triphenyl phosphate | affects expression | ISO | DESI2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of DESI2 mRNA | CTD | PMID:37042841 | Desi2 | Rat | urethane | increases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Urethane results in increased expression of DESI2 mRNA | CTD | PMID:28818685 | Desi2 | Rat | valproic acid | decreases methylation | ISO | DESI2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of DESI2 gene | CTD | PMID:29154799 | Desi2 | Rat | valproic acid | decreases expression | ISO | DESI2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DESI2 mRNA | CTD | PMID:28001369 | Desi2 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of DESI2 mRNA | CTD | PMID:19015723 | Desi2 | Rat | vorinostat | multiple interactions | ISO | DESI2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... | CTD | PMID:27188386 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















