Desi2 (desumoylating isopeptidase 2) - Rat Genome Database

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Pathways
Gene: Desi2 (desumoylating isopeptidase 2) Rattus norvegicus
Analyze
Symbol: Desi2
Name: desumoylating isopeptidase 2
RGD ID: 1359392
Description: Predicted to enable deubiquitinase activity and long-chain fatty acyl-CoA hydrolase activity. Predicted to be involved in macromolecule depalmitoylation and proteolysis. Predicted to be located in cytoplasm. Orthologous to human DESI2 (desumoylating isopeptidase 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CGI-146; DeSI-2; deubiquitinase DESI2; Fam152a; family with sequence similarity 152, member A; palmitoyl protein thioesterase DESI2; PNAS-4; PPPDE peptidase domain containing 1; PPPDE peptidase domain-containing protein 1; Pppde1; S-depalmitoylase DESI2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81392,493,765 - 92,543,307 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1392,493,989 - 92,564,981 (+)EnsemblGRCr8
mRatBN7.21389,961,767 - 90,011,255 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1389,961,934 - 90,016,416 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1392,467,195 - 92,510,053 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01393,867,337 - 93,910,193 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,048,646 - 91,091,598 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01396,111,800 - 96,156,693 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1396,111,800 - 96,154,685 (+)Ensemblrn6Rnor6.0
Rnor_5.013100,553,747 - 100,599,426 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41393,895,171 - 93,903,458 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1389,520,725 - 89,563,808 (+)NCBICelera
RGSC_v3.11394,084,106 - 94,092,392 (+)NCBI
Cytogenetic Map13q25NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:21553223   PMID:22370726   PMID:28483520   PMID:33794264  


Genomics

Comparative Map Data
Desi2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81392,493,765 - 92,543,307 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1392,493,989 - 92,564,981 (+)EnsemblGRCr8
mRatBN7.21389,961,767 - 90,011,255 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1389,961,934 - 90,016,416 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1392,467,195 - 92,510,053 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01393,867,337 - 93,910,193 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,048,646 - 91,091,598 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01396,111,800 - 96,156,693 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1396,111,800 - 96,154,685 (+)Ensemblrn6Rnor6.0
Rnor_5.013100,553,747 - 100,599,426 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41393,895,171 - 93,903,458 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1389,520,725 - 89,563,808 (+)NCBICelera
RGSC_v3.11394,084,106 - 94,092,392 (+)NCBI
Cytogenetic Map13q25NCBI
DESI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381244,653,126 - 244,709,033 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1244,653,091 - 244,709,033 (+)Ensemblhg38GRCh38
GRCh371244,816,428 - 244,872,335 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361242,882,975 - 242,938,958 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1218,106,243 - 218,162,211 (+)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1215,199,549 - 215,255,506 (+)NCBIHuRef
CHM1_11246,088,656 - 246,144,628 (+)NCBICHM1_1
T2T-CHM13v2.01244,069,385 - 244,125,271 (+)NCBIT2T-CHM13v2.0
Desi2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,014,983 - 178,080,164 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,014,983 - 178,084,867 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381178,187,417 - 178,252,598 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,187,417 - 178,257,301 (+)Ensemblmm10GRCm38
MGSCv371180,117,548 - 180,182,729 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361180,024,385 - 180,089,269 (+)NCBIMGSCv36mm8
Celera1185,247,627 - 185,312,483 (+)NCBICelera
Cytogenetic Map1H4NCBI
cM Map182.93NCBI
Desi2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554067,880,648 - 7,894,629 (+)Ensembl
ChiLan1.0NW_0049554067,881,815 - 7,894,690 (+)NCBIChiLan1.0ChiLan1.0
DESI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v214,448,197 - 4,507,060 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114,670,620 - 4,726,951 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01220,246,390 - 220,302,577 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11225,626,913 - 225,682,778 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1225,626,913 - 225,682,772 (+)EnsemblpanPan2panpan1.1
DESI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1735,688,519 - 35,734,283 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl735,687,888 - 35,731,186 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha735,161,634 - 35,208,048 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0735,516,735 - 35,563,360 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl735,516,660 - 35,563,350 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1735,352,288 - 35,398,850 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0735,367,194 - 35,413,792 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0735,632,821 - 35,679,443 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Desi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934448,566,633 - 48,617,795 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365266,129,500 - 6,180,668 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365266,130,714 - 6,180,546 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DESI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1017,365,689 - 17,416,635 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11017,365,649 - 17,416,642 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21019,696,102 - 19,747,165 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DESI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12581,670,135 - 81,733,696 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2581,670,170 - 81,733,812 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605583,892,549 - 83,956,201 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Desi2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477114,879,277 - 14,927,002 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477114,879,275 - 14,927,352 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Desi2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11056,546,922 - 56,591,376 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Desi2
192 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:213
Count of miRNA genes:149
Interacting mature miRNAs:165
Transcripts:ENSRNOT00000005967
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1383286150109350286Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
1302791Stl29Serum triglyceride level QTL 293.30.0011blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)138933312992500981Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
RH133177  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,004,865 - 90,005,075 (+)MAPPERmRatBN7.2
Rnor_6.01396,154,763 - 96,154,972NCBIRnor6.0
Rnor_5.013100,597,496 - 100,597,705UniSTSRnor5.0
RGSC_v3.41393,903,532 - 93,903,741UniSTSRGSC3.4
Celera1389,563,882 - 89,564,091UniSTS
RH 3.4 Map13607.5UniSTS
Cytogenetic Map13q25UniSTS
RH144438  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,004,372 - 90,004,497 (+)MAPPERmRatBN7.2
Rnor_6.01396,154,270 - 96,154,394NCBIRnor6.0
Rnor_5.013100,597,003 - 100,597,127UniSTSRnor5.0
RGSC_v3.41393,903,039 - 93,903,163UniSTSRGSC3.4
Celera1389,563,389 - 89,563,513UniSTS
RH 3.4 Map13608.5UniSTS
Cytogenetic Map13q25UniSTS
BI293545  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21389,977,262 - 89,977,412 (+)MAPPERmRatBN7.2
Rnor_6.01396,127,116 - 96,127,265NCBIRnor6.0
Rnor_5.013100,570,275 - 100,570,424UniSTSRnor5.0
Celera1389,536,259 - 89,536,408UniSTS
RH 3.4 Map13605.9UniSTS
Cytogenetic Map13q25UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001013873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC083584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000005967   ⟹   ENSRNOP00000005967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,494,188 - 92,537,255 (+)Ensembl
mRatBN7.2 Ensembl1389,961,934 - 90,004,788 (+)Ensembl
Rnor_6.0 Ensembl1396,111,800 - 96,154,685 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087964   ⟹   ENSRNOP00000069021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,493,989 - 92,564,981 (+)Ensembl
mRatBN7.2 Ensembl1389,961,934 - 90,016,416 (+)Ensembl
Rnor_6.0 Ensembl1396,122,120 - 96,153,823 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000096311   ⟹   ENSRNOP00000090662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,523,702 - 92,537,255 (+)Ensembl
mRatBN7.2 Ensembl1389,991,647 - 90,004,805 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098343   ⟹   ENSRNOP00000091146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,494,994 - 92,537,255 (+)Ensembl
mRatBN7.2 Ensembl1389,971,669 - 90,004,805 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108395   ⟹   ENSRNOP00000091139
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,522,997 - 92,537,255 (+)Ensembl
mRatBN7.2 Ensembl1389,990,942 - 90,004,805 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000115830   ⟹   ENSRNOP00000090046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,494,158 - 92,537,255 (+)Ensembl
mRatBN7.2 Ensembl1389,962,414 - 90,004,805 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000130824   ⟹   ENSRNOP00000103188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,494,149 - 92,535,934 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000149431   ⟹   ENSRNOP00000100406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,523,884 - 92,548,465 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000149433   ⟹   ENSRNOP00000107831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1392,494,140 - 92,535,934 (+)Ensembl
RefSeq Acc Id: NM_001013873   ⟹   NP_001013895
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,989 - 92,536,844 (+)NCBI
mRatBN7.21389,961,934 - 90,004,792 (+)NCBI
Rnor_6.01396,111,800 - 96,154,689 (+)NCBI
Rnor_5.013100,553,747 - 100,599,426 (+)NCBI
RGSC_v3.41393,895,171 - 93,903,458 (+)RGD
Celera1389,520,725 - 89,563,808 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250317   ⟹   XP_006250379
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,948 - 92,543,307 (+)NCBI
mRatBN7.21389,961,812 - 90,011,255 (+)NCBI
Rnor_6.01396,111,960 - 96,156,693 (+)NCBI
Rnor_5.013100,553,747 - 100,599,426 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598724   ⟹   XP_017454213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,948 - 92,543,307 (+)NCBI
mRatBN7.21389,962,245 - 90,011,255 (+)NCBI
Rnor_6.01396,111,960 - 96,156,693 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017598725   ⟹   XP_017454214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,494,498 - 92,543,307 (+)NCBI
mRatBN7.21389,962,854 - 90,011,255 (+)NCBI
Rnor_6.01396,112,259 - 96,156,693 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090529   ⟹   XP_038946457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,494,500 - 92,543,307 (+)NCBI
mRatBN7.21389,962,854 - 90,011,255 (+)NCBI
RefSeq Acc Id: XM_039090530   ⟹   XP_038946458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,765 - 92,543,307 (+)NCBI
mRatBN7.21389,961,767 - 90,011,255 (+)NCBI
RefSeq Acc Id: XM_039090532   ⟹   XP_038946460
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,493,766 - 92,532,185 (+)NCBI
mRatBN7.21389,961,772 - 90,003,485 (+)NCBI
RefSeq Acc Id: XM_063272134   ⟹   XP_063128204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,499,411 - 92,543,307 (+)NCBI
RefSeq Acc Id: XM_063272135   ⟹   XP_063128205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,499,411 - 92,543,307 (+)NCBI
RefSeq Acc Id: XM_063272136   ⟹   XP_063128206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,495,233 - 92,543,307 (+)NCBI
RefSeq Acc Id: XM_063272137   ⟹   XP_063128207
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81392,499,401 - 92,543,307 (+)NCBI
RefSeq Acc Id: NP_001013895   ⟸   NM_001013873
- UniProtKB: Q5XIT6 (UniProtKB/Swiss-Prot),   A0A8I6GJD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250379   ⟸   XM_006250317
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AD20 (UniProtKB/TrEMBL),   A0A8I6AER3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454213   ⟸   XM_017598724
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AF15 (UniProtKB/TrEMBL),   A0A8I6GJD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017454214   ⟸   XM_017598725
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AF15 (UniProtKB/TrEMBL),   A0A8I6GJD8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069021   ⟸   ENSRNOT00000087964
Ensembl Acc Id: ENSRNOP00000005967   ⟸   ENSRNOT00000005967
RefSeq Acc Id: XP_038946458   ⟸   XM_039090530
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038946460   ⟸   XM_039090532
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038946457   ⟸   XM_039090529
- Peptide Label: isoform X3
- UniProtKB: A0A8I6GJD8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000090046   ⟸   ENSRNOT00000115830
Ensembl Acc Id: ENSRNOP00000090662   ⟸   ENSRNOT00000096311
Ensembl Acc Id: ENSRNOP00000091146   ⟸   ENSRNOT00000098343
Ensembl Acc Id: ENSRNOP00000091139   ⟸   ENSRNOT00000108395
RefSeq Acc Id: XP_063128206   ⟸   XM_063272136
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AD20 (UniProtKB/TrEMBL),   A0A8I6AER3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128207   ⟸   XM_063272137
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063128204   ⟸   XM_063272134
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AF15 (UniProtKB/TrEMBL),   A0A8I6GJD8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128205   ⟸   XM_063272135
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AF15 (UniProtKB/TrEMBL),   A0A8I6GJD8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000107831   ⟸   ENSRNOT00000149433
Ensembl Acc Id: ENSRNOP00000103188   ⟸   ENSRNOT00000130824
Ensembl Acc Id: ENSRNOP00000100406   ⟸   ENSRNOT00000149431
Protein Domains
PPPDE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XIT6-F1-model_v2 AlphaFold Q5XIT6 1-194 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699046
Promoter ID:EPDNEW_R9571
Type:initiation region
Name:Desi2_1
Description:desumoylating isopeptidase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01396,111,976 - 96,112,036EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359392 AgrOrtholog
BioCyc Gene G2FUF-17177 BioCyc
Ensembl Genes ENSRNOG00000004524 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005967 ENTREZGENE
  ENSRNOT00000005967.8 UniProtKB/Swiss-Prot
  ENSRNOT00000098343 ENTREZGENE
  ENSRNOT00000130824 ENTREZGENE
  ENSRNOT00000149433 ENTREZGENE
Gene3D-CATH 3.90.1720.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7131107 IMAGE-MGC_LOAD
InterPro PPPDE_dom UniProtKB/Swiss-Prot
  PPPDE_sf UniProtKB/Swiss-Prot
KEGG Report rno:289277 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94230 IMAGE-MGC_LOAD
NCBI Gene 289277 ENTREZGENE
PANTHER DEUBIQUITINASE DESI2 UniProtKB/Swiss-Prot
  PTHR12378 UniProtKB/Swiss-Prot
Pfam Peptidase_C97 UniProtKB/Swiss-Prot
PhenoGen Desi2 PhenoGen
PROSITE PPPDE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004524 RatGTEx
SMART DUF862 UniProtKB/Swiss-Prot
UniProt A0A0G2JUA0_RAT UniProtKB/TrEMBL
  A0A8I6AD20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AER3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AF15 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJD8 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LEU4_RAT UniProtKB/TrEMBL
  A0ABK0LJK0_RAT UniProtKB/TrEMBL
  A0ABK0LWD6_RAT UniProtKB/TrEMBL
  DESI2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Desi2  desumoylating isopeptidase 2  Pppde1  PPPDE peptidase domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-02-23 Pppde1  PPPDE peptidase domain containing 1  Fam152a  family with sequence similarity 152, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Fam152a  family with sequence similarity 152, member A  PNAS-4  CGI-146 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-29 PNAS-4  CGI-146 protein      Symbol and Name status set to provisional 70820 PROVISIONAL