Abhd6 (abhydrolase domain containing 6, acylglycerol lipase) - Rat Genome Database

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Gene: Abhd6 (abhydrolase domain containing 6, acylglycerol lipase) Rattus norvegicus
Analyze
Symbol: Abhd6
Name: abhydrolase domain containing 6, acylglycerol lipase
RGD ID: 1359323
Description: Predicted to enable monoacylglycerol lipase activity and phospholipase activity. Predicted to be involved in several processes, including monoacylglycerol catabolic process; negative regulation of cold-induced thermogenesis; and phospholipid metabolic process. Predicted to act upstream of or within long-term synaptic depression; negative regulation of cell migration; and regulation of endocannabinoid signaling pathway. Predicted to be located in late endosome membrane; lysosomal membrane; and mitochondrion. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Orthologous to human ABHD6 (abhydrolase domain containing 6, acylglycerol lipase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2-arachidonoylglycerol hydrolase; abhydrolase domain containing 6; abhydrolase domain-containing protein 6; MGC94917; monoacylglycerol lipase ABHD6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81519,289,967 - 19,337,500 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1519,289,969 - 19,337,193 (-)EnsemblGRCr8
mRatBN7.21516,859,740 - 16,907,094 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1516,859,738 - 16,906,985 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1519,034,098 - 19,081,627 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01519,992,574 - 20,040,102 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01518,247,481 - 18,295,013 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01518,647,903 - 18,695,133 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1518,647,844 - 18,695,133 (-)Ensemblrn6Rnor6.0
Rnor_5.01522,614,361 - 22,661,344 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41518,846,512 - 18,894,003 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1516,815,723 - 16,863,221 (-)NCBICelera
RGSC_v3.11518,846,513 - 18,894,003 (-)NCBI
Cytogenetic Map15p14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-arachidonoylglycerol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
azoxystrobin  (ISO)
Benoxacor  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
Cyclopamine  (ISO)
cyclosporin A  (ISO)
diazinon  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloroacetic acid  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
finasteride  (EXP)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
inulin  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
oxaliplatin  (EXP)
oxycodone  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. null JRS Domain-based curation
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
7. alpha/beta-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes. Zhao S, etal., Cell Rep. 2016 Mar 29;14(12):2872-88. doi: 10.1016/j.celrep.2016.02.076. Epub 2016 Mar 17.
Additional References at PubMed
PMID:15489334   PMID:18096503   PMID:20657592   PMID:22632720   PMID:22969151   PMID:23376485   PMID:24095738   PMID:26491015   PMID:34468198  


Genomics

Comparative Map Data
Abhd6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81519,289,967 - 19,337,500 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1519,289,969 - 19,337,193 (-)EnsemblGRCr8
mRatBN7.21516,859,740 - 16,907,094 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1516,859,738 - 16,906,985 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1519,034,098 - 19,081,627 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01519,992,574 - 20,040,102 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01518,247,481 - 18,295,013 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01518,647,903 - 18,695,133 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1518,647,844 - 18,695,133 (-)Ensemblrn6Rnor6.0
Rnor_5.01522,614,361 - 22,661,344 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41518,846,512 - 18,894,003 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1516,815,723 - 16,863,221 (-)NCBICelera
RGSC_v3.11518,846,513 - 18,894,003 (-)NCBI
Cytogenetic Map15p14NCBI
ABHD6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38358,237,792 - 58,294,734 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl358,237,516 - 58,295,693 (+)Ensemblhg38GRCh38
GRCh37358,223,519 - 58,280,461 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36358,198,349 - 58,255,501 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34358,198,348 - 58,255,499NCBI
Celera358,237,772 - 58,295,009 (+)NCBICelera
Cytogenetic Map3p14.3NCBI
HuRef358,320,101 - 58,376,917 (+)NCBIHuRef
CHM1_1358,173,601 - 58,230,753 (+)NCBICHM1_1
T2T-CHM13v2.0358,278,191 - 58,335,141 (+)NCBIT2T-CHM13v2.0
Abhd6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391414,413,000 - 14,466,885 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1414,413,010 - 14,466,871 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38148,002,888 - 8,056,773 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl148,002,902 - 8,056,763 (+)Ensemblmm10GRCm38
MGSCv37148,835,416 - 8,889,069 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36146,794,781 - 6,848,434 (+)NCBIMGSCv36mm8
Celera143,626,234 - 3,679,797 (+)NCBICelera
Cytogenetic Map14A1NCBI
cM Map144.69NCBI
Abhd6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554301,808,924 - 1,861,441 (-)Ensembl
ChiLan1.0NW_0049554301,809,969 - 1,861,441 (-)NCBIChiLan1.0ChiLan1.0
ABHD6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2258,207,823 - 58,262,962 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1358,212,597 - 58,267,740 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0358,172,334 - 58,227,531 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1359,586,537 - 59,641,824 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl359,586,573 - 59,641,824 (+)EnsemblpanPan2panpan1.1
ABHD6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12032,301,120 - 32,331,030 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2032,302,104 - 32,330,998 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2032,230,178 - 32,271,085 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02032,573,573 - 32,614,688 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2032,573,597 - 32,614,474 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12032,029,624 - 32,070,713 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02032,386,128 - 32,427,061 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02032,557,760 - 32,599,072 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Abhd6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118169,549,211 - 169,593,878 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364732,687,746 - 2,732,473 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364732,687,784 - 2,732,413 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1340,009,737 - 40,060,394 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11339,982,536 - 40,055,467 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21343,989,292 - 44,015,528 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ABHD6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12219,530,543 - 19,593,083 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2219,542,161 - 19,582,310 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041147,247,753 - 147,302,666 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248225,336,427 - 5,376,721 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248225,332,197 - 5,376,372 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Abhd6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11278,443,697 - 78,487,602 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Abhd6
437 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:337
Count of miRNA genes:197
Interacting mature miRNAs:233
Transcripts:ENSRNOT00000012271
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat

Markers in Region
D15Rat138  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21516,887,573 - 16,887,753 (+)MAPPERmRatBN7.2
Rnor_6.01518,675,740 - 18,675,919NCBIRnor6.0
Rnor_5.01522,642,195 - 22,642,374NCBIRnor5.0
RGSC_v3.41518,874,347 - 18,874,526UniSTSRGSC3.4
Celera1516,843,876 - 16,844,055UniSTS
SHRSP x BN Map1515.3399UniSTS
SHRSP x BN Map1515.3399RGD
Cytogenetic Map15p14UniSTS
RH128805  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81519,290,130 - 19,290,318 (+)Marker Load Pipeline
mRatBN7.21516,859,903 - 16,860,091 (+)MAPPERmRatBN7.2
Rnor_6.01518,648,069 - 18,648,256NCBIRnor6.0
Rnor_5.01522,614,527 - 22,614,714UniSTSRnor5.0
RGSC_v3.41518,846,676 - 18,846,863UniSTSRGSC3.4
Celera1516,815,887 - 16,816,074UniSTS
RH 3.4 Map15139.7UniSTS
Cytogenetic Map15p14UniSTS
AV065425  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21516,860,720 - 16,860,812 (+)MAPPERmRatBN7.2
Rnor_6.01518,648,886 - 18,648,977NCBIRnor6.0
Rnor_5.01522,615,344 - 22,615,435UniSTSRnor5.0
RGSC_v3.41518,847,493 - 18,847,584UniSTSRGSC3.4
Celera1516,816,704 - 16,816,795UniSTS
Cytogenetic Map15p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012271   ⟹   ENSRNOP00000012271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1519,289,969 - 19,337,193 (-)Ensembl
mRatBN7.2 Ensembl1516,859,738 - 16,906,985 (-)Ensembl
Rnor_6.0 Ensembl1518,647,907 - 18,695,133 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000080794   ⟹   ENSRNOP00000074573
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1519,289,969 - 19,317,495 (-)Ensembl
mRatBN7.2 Ensembl1516,859,738 - 16,884,547 (-)Ensembl
Rnor_6.0 Ensembl1518,647,844 - 18,675,431 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000155947   ⟹   ENSRNOP00000109306
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1519,289,969 - 19,337,123 (-)Ensembl
RefSeq Acc Id: NM_001007680   ⟹   NP_001007681
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81519,289,967 - 19,337,193 (-)NCBI
mRatBN7.21516,859,740 - 16,906,970 (-)NCBI
Rnor_6.01518,647,905 - 18,695,133 (-)NCBI
Rnor_5.01522,614,361 - 22,661,344 (-)NCBI
RGSC_v3.41518,846,512 - 18,894,003 (-)RGD
Celera1516,815,723 - 16,863,221 (-)RGD
Sequence:
RefSeq Acc Id: XM_006251767   ⟹   XP_006251829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81519,289,967 - 19,337,154 (-)NCBI
mRatBN7.21516,859,740 - 16,906,909 (-)NCBI
Rnor_6.01518,647,903 - 18,695,081 (-)NCBI
Rnor_5.01522,614,361 - 22,661,344 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093252   ⟹   XP_038949180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81519,289,967 - 19,305,070 (-)NCBI
mRatBN7.21516,859,740 - 16,874,845 (-)NCBI
RefSeq Acc Id: XM_063274199   ⟹   XP_063130269
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81519,289,967 - 19,317,490 (-)NCBI
RefSeq Acc Id: XM_063274201   ⟹   XP_063130271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81519,291,931 - 19,337,500 (-)NCBI
RefSeq Acc Id: NP_001007681   ⟸   NM_001007680
- UniProtKB: Q5XI64 (UniProtKB/Swiss-Prot),   A6K0C2 (UniProtKB/TrEMBL),   A0A8L2R9X1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251829   ⟸   XM_006251767
- Peptide Label: isoform X1
- UniProtKB: Q5XI64 (UniProtKB/Swiss-Prot),   A6K0C2 (UniProtKB/TrEMBL),   A0A8L2R9X1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074573   ⟸   ENSRNOT00000080794
Ensembl Acc Id: ENSRNOP00000012271   ⟸   ENSRNOT00000012271
RefSeq Acc Id: XP_038949180   ⟸   XM_039093252
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063130269   ⟸   XM_063274199
- Peptide Label: isoform X2
- UniProtKB: A0A8L2R9X1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130271   ⟸   XM_063274201
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000109306   ⟸   ENSRNOT00000155947
Protein Domains
AB hydrolase-1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5XI64-F1-model_v2 AlphaFold Q5XI64 1-337 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699591
Promoter ID:EPDNEW_R10114
Type:multiple initiation site
Name:Abhd6_1
Description:abhydrolase domain containing 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01518,695,116 - 18,695,176EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359323 AgrOrtholog
BioCyc Gene G2FUF-14285 BioCyc
BioCyc Pathway LIPAS-PWY [triacylglycerol degradation] BioCyc
  PWY-7420 [monoacylglycerol metabolism (yeast)] BioCyc
BioCyc Pathway Image LIPAS-PWY BioCyc
  PWY-7420 BioCyc
Ensembl Genes ENSRNOG00000008167 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000012271 ENTREZGENE
  ENSRNOT00000012271.5 UniProtKB/Swiss-Prot
  ENSRNOT00000080794 ENTREZGENE
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7112208 IMAGE-MGC_LOAD
InterPro AB_hydrolase UniProtKB/Swiss-Prot
  AB_hydrolase_1 UniProtKB/Swiss-Prot
  AB_hydrolase_sf UniProtKB/Swiss-Prot
  Epox_hydrolase-like UniProtKB/Swiss-Prot
KEGG Report rno:305795 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94917 IMAGE-MGC_LOAD
NCBI Gene 305795 ENTREZGENE
PANTHER MONOACYLGLYCEROL LIPASE UniProtKB/Swiss-Prot
  MONOACYLGLYCEROL LIPASE ABHD6 UniProtKB/Swiss-Prot
Pfam Abhydrolase_1 UniProtKB/Swiss-Prot
PhenoGen Abhd6 PhenoGen
PRINTS ABHYDROLASE UniProtKB/Swiss-Prot
  EPOXHYDRLASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008167 RatGTEx
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot
UniProt A0A8L2R9X1 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0M2W1_RAT UniProtKB/TrEMBL
  A6K0C2 ENTREZGENE, UniProtKB/TrEMBL
  ABHD6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-13 Abhd6  abhydrolase domain containing 6, acylglycerol lipase  Abhd6  abhydrolase domain containing 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Abhd6  abhydrolase domain containing 6      Symbol and Name status set to approved 1299863 APPROVED
2005-07-29 Abhd6  abhydrolase domain containing 6      Symbol and Name status set to provisional 70820 PROVISIONAL