Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (S)-nicotine | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Nicotine results in increased expression of PTBP2 mRNA | CTD | PMID:16949557 | 1,2-dimethylhydrazine | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PTBP2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of PTBP2 mRNA | CTD | PMID:17557909 | 17alpha-ethynylestradiol | affects expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of PTBP2 mRNA | CTD | PMID:17555576 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PTBP2 mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of PTBP2 protein | CTD | PMID:34915118 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PTBP2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | bisphenol S results in decreased expression of PTBP2 mRNA | CTD | PMID:30616060 | 4-hydroxyphenyl retinamide | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of PTBP2 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PTBP2 mRNA | CTD | PMID:30047161 | aflatoxin B1 | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of PTBP2 mRNA | CTD | PMID:19770486 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of PTBP2 mRNA | CTD | PMID:30047161 | antirheumatic drug | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of PTBP2 mRNA | CTD | PMID:24449571 | aristolochic acid A | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of PTBP2 protein | CTD | PMID:33212167 | aristolochic acid A | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of PTBP2 mRNA | CTD | PMID:33212167 | atrazine | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Atrazine results in increased expression of PTBP2 mRNA | CTD | PMID:22378314 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of PTBP2 gene | CTD | PMID:28931070 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of PTBP2 gene | CTD | PMID:28505145 | bisphenol A | decreases methylation | ISO | PTBP2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of PTBP2 gene | CTD | PMID:31601247 | bisphenol A | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PTBP2 mRNA | CTD | PMID:33221593 | bisphenol A | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PTBP2 mRNA | CTD | PMID:28628672 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of PTBP2 mRNA | CTD | PMID:33453195 | chlorpyrifos | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of PTBP2 mRNA | CTD | PMID:37019170 | cisplatin | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of PTBP2 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of PTBP2 mRNA | CTD | PMID:27392435 | clobetasol | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Clobetasol results in decreased expression of PTBP2 mRNA | CTD | PMID:27462272 | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of PTBP2 mRNA | CTD | PMID:30556269 | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of PTBP2 mRNA | CTD | PMID:30556269 | Cuprizon | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Cuprizone results in decreased expression of PTBP2 protein | CTD | PMID:34122009 | cyclosporin A | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PTBP2 mRNA | CTD | PMID:27989131 | delta-tocotrienol | multiple interactions | ISO | Ptbp2 (Mus musculus) | 6480464 | tocotrienol and delta inhibits the reaction [Lipopolysaccharides results in decreased expression of PTBP2 mRNA] | CTD | PMID:22185406 | delta-tocotrienol | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | tocotrienol and delta results in increased expression of PTBP2 mRNA | CTD | PMID:22185406 | dexamethasone | multiple interactions | ISO | Ptbp2 (Mus musculus) | 6480464 | Dexamethasone inhibits the reaction [Lipopolysaccharides results in decreased expression of PTBP2 mRNA] | CTD | PMID:22185406 | dexamethasone | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PTBP2 mRNA | CTD | PMID:28628672 | dexamethasone | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of PTBP2 mRNA | CTD | PMID:22185406 | dibutyl phthalate | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of PTBP2 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of PTBP2 mRNA | CTD | PMID:24893172 | diethylstilbestrol | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of PTBP2 mRNA | CTD | PMID:36621641 | dioxygen | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of PTBP2 mRNA | CTD | PMID:24205000 | dorsomorphin | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PTBP2 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PTBP2 mRNA | CTD | PMID:29803840 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of PTBP2 mRNA | CTD | PMID:27387713 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of PTBP2 mRNA | CTD | PMID:33387578 | gold atom | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Gold results in decreased expression of PTBP2 mRNA | CTD | PMID:25523186 | gold(0) | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Gold results in decreased expression of PTBP2 mRNA | CTD | PMID:25523186 | indometacin | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of PTBP2 mRNA | CTD | PMID:28628672 | levonorgestrel | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PTBP2 mRNA | CTD | PMID:19074003 | lipopolysaccharide | multiple interactions | ISO | Ptbp2 (Mus musculus) | 6480464 | Dexamethasone inhibits the reaction [Lipopolysaccharides results in decreased expression of PTBP2 mRNA] more ... | CTD | PMID:22185406 | lipopolysaccharide | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Lipopolysaccharides results in decreased expression of PTBP2 mRNA | CTD | PMID:22185406 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of PTBP2 mRNA | CTD | PMID:30047161 | methyl methanesulfonate | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of PTBP2 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PTBP2 mRNA | CTD | PMID:28001369 | mifepristone | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Mifepristone results in increased expression of PTBP2 mRNA | CTD | PMID:17584828 | nicotine | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Nicotine results in increased expression of PTBP2 mRNA | CTD | PMID:16949557 | obeticholic acid | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | obeticholic acid results in decreased expression of PTBP2 mRNA | CTD | PMID:27939613 | paracetamol | affects expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PTBP2 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of PTBP2 mRNA | CTD | PMID:33387578 | phenobarbital | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of PTBP2 mRNA | CTD | PMID:19270015 | phenobarbital | affects expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of PTBP2 mRNA | CTD | PMID:23091169 | phenylmercury acetate | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of PTBP2 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PTBP2 mRNA | CTD | PMID:27188386 | phenytoin | increases expression | EXP | | 6480464 | Phenytoin results in increased expression of PTBP2 mRNA | CTD | PMID:20345932 | pirinixic acid | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of PTBP2 mRNA | CTD | PMID:18301758 and PMID:18445702 | potassium dichromate | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of PTBP2 mRNA | CTD | PMID:23608068 | pregnenolone 16alpha-carbonitrile | decreases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in decreased expression of PTBP2 mRNA | CTD | PMID:30047161 | progesterone | affects expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Progesterone affects the expression of PTBP2 mRNA | CTD | PMID:17251523 | quercetin | multiple interactions | ISO | Ptbp2 (Mus musculus) | 6480464 | Quercetin inhibits the reaction [Lipopolysaccharides results in decreased expression of PTBP2 mRNA] | CTD | PMID:22185406 | quercetin | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of PTBP2 mRNA | CTD | PMID:21632981 | quercetin | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Quercetin results in decreased expression of PTBP2 mRNA | CTD | PMID:22185406 | SB 431542 | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | silver atom | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Silver results in decreased expression of PTBP2 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Silver results in decreased expression of PTBP2 mRNA | CTD | PMID:27131904 | sodium arsenate | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of PTBP2 mRNA | CTD | PMID:21795629 and PMID:27751817 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of PTBP2 mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of PTBP2 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of PTBP2 mRNA | CTD | PMID:17555576 | temozolomide | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of PTBP2 mRNA | CTD | PMID:31758290 | tert-butyl hydroperoxide | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of PTBP2 mRNA | CTD | PMID:15336504 | testosterone | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of PTBP2 mRNA | CTD | PMID:33359661 | testosterone undecanoate | multiple interactions | ISO | PTBP2 (Homo sapiens) | 6480464 | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of PTBP2 mRNA | CTD | PMID:19074003 | tetrachloromethane | affects expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of PTBP2 mRNA | CTD | PMID:17484886 | tetrachloromethane | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of PTBP2 mRNA | CTD | PMID:31919559 | thimerosal | increases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Thimerosal results in increased expression of PTBP2 mRNA | CTD | PMID:27188386 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PTBP2 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of PTBP2 gene | CTD | PMID:27618143 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of PTBP2 mRNA | CTD | PMID:33387578 | tris(2-butoxyethyl) phosphate | affects expression | ISO | PTBP2 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of PTBP2 mRNA | CTD | PMID:29024780 | trovafloxacin | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of PTBP2 mRNA | CTD | PMID:35537566 | tungsten | increases expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Tungsten results in increased expression of PTBP2 mRNA | CTD | PMID:30912803 | valproic acid | decreases methylation | ISO | PTBP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of PTBP2 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PTBP2 mRNA | CTD | PMID:23179753 more ... | valproic acid | affects expression | ISO | PTBP2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PTBP2 mRNA | CTD | PMID:24849673 and PMID:25979313 | valproic acid | affects expression | ISO | Ptbp2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of PTBP2 mRNA | CTD | PMID:17963808 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of PTBP2 mRNA | CTD | PMID:23869203 | |