Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | RCHY1 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | |
|
Imported Disease Annotations - ClinVarTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | genetic disease | | ISO | RCHY1 (Homo sapiens) | 8554872 | ClinVar Annotator: match by term: Inborn genetic diseases | ClinVar | | |
|
|
|
|
|
|
|
|
|
|
|
|
# | Reference Title | Reference Citation |
1. | Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit. | Abe K, etal., Biomed Res. 2008 Feb;29(1):53-60. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
4. | Modes of p53 regulation. | Kruse JP and Gu W, Cell. 2009 May 15;137(4):609-22. doi: 10.1016/j.cell.2009.04.050. |
5. | Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. | Leng RP, etal., Cell 2003 Mar 21;112(6):779-91. |
6. | Dynamic changes of PIRH2 and p27kip1 expression in injured rat sciatic nerve. | Li H, etal., Neurol Sci. 2012 Aug;33(4):749-57. doi: 10.1007/s10072-011-0809-8. Epub 2011 Sep 30. |
7. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
8. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
9. | GOA pipeline | RGD automated data pipeline |
10. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
11. | Comprehensive gene review and curation | RGD comprehensive gene curation |
12. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
13. | Changes in Pirh2 and p27kip1 expression following traumatic brain injury in adult rats. | Wu X, etal., J Mol Neurosci. 2012 Jan;46(1):184-91. doi: 10.1007/s12031-011-9572-9. Epub 2011 Jul 5. |
Rchy1 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RCHY1 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rchy1 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rchy1 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RCHY1 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RCHY1 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rchy1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RCHY1 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
RCHY1 (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rchy1 (Heterocephalus glaber - naked mole-rat) |
|
.
Variants in Rchy1
100 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH127475 |
|
alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 43 | 57 | 41 | 19 | 41 | 8 | 11 | 74 | 35 | 41 | 11 | 8 |
Low | |||||||||||||
Below cutoff |
RefSeq Transcripts | NM_001007618 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_039091675 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC136013 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BC083739 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC105864 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH474060 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ216834 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000014 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000003470 ⟹ ENSRNOP00000003470 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | ENSRNOT00000104798 ⟹ ENSRNOP00000084319 | ||||||||
Type: | CODING | ||||||||
Position: |
|
RefSeq Acc Id: | NM_001007618 ⟹ NP_001007619 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
|
||||||||||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_039091675 ⟹ XP_038947603 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
Protein RefSeqs | NP_001007619 | (Get FASTA) | NCBI Sequence Viewer |
XP_038947603 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAH83739 | (Get FASTA) | NCBI Sequence Viewer |
EDL88590 | (Get FASTA) | NCBI Sequence Viewer | |
EDL88591 | (Get FASTA) | NCBI Sequence Viewer | |
EDL88592 | (Get FASTA) | NCBI Sequence Viewer | |
EDL88593 | (Get FASTA) | NCBI Sequence Viewer | |
EDL88594 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000003470 | ||
ENSRNOP00000003470.3 | |||
ENSRNOP00000084319.1 |
RefSeq Acc Id: | NP_001007619 ⟸ NM_001007618 |
- UniProtKB: | Q5XIE4 (UniProtKB/TrEMBL), A6KKB6 (UniProtKB/TrEMBL), A0A8I5ZWY8 (UniProtKB/TrEMBL), A6KKB7 (UniProtKB/TrEMBL), F7F3N3 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000003470 ⟸ ENSRNOT00000003470 |
RefSeq Acc Id: | XP_038947603 ⟸ XM_039091675 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A6KKC0 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | ENSRNOP00000084319 ⟸ ENSRNOT00000104798 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q5XIE4-F1-model_v2 | AlphaFold | Q5XIE4 | 1-261 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13699218 | ||||||||
Promoter ID: | EPDNEW_R9743 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Rchy1_1 | ||||||||
Description: | ring finger and CHY zinc finger domain containing 1 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
|
Database | Acc Id | Source(s) |
AGR Gene | RGD:1359180 | AgrOrtholog |
BioCyc Gene | G2FUF-16238 | BioCyc |
Ensembl Genes | ENSRNOG00000002546 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000003470 | ENTREZGENE |
ENSRNOT00000003470.5 | UniProtKB/TrEMBL | |
ENSRNOT00000104798.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.20.28.10 | UniProtKB/TrEMBL |
3.30.40.10 | UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7191744 | IMAGE-MGC_LOAD |
InterPro | RCHY1_zinc-ribbon | UniProtKB/TrEMBL |
Znf_CHY | UniProtKB/TrEMBL | |
Znf_CHY_sf | UniProtKB/TrEMBL | |
Znf_CTCHY | UniProtKB/TrEMBL | |
Znf_CTCHY_sf | UniProtKB/TrEMBL | |
Znf_RING | UniProtKB/TrEMBL | |
Znf_RING/FYVE/PHD | UniProtKB/TrEMBL | |
MGC_CLONE | MGC:94651 | IMAGE-MGC_LOAD |
NCBI Gene | 289508 | ENTREZGENE |
PANTHER | RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 | UniProtKB/TrEMBL |
RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 | UniProtKB/TrEMBL | |
Pfam | zf-CHY | UniProtKB/TrEMBL |
zf-RING_2 | UniProtKB/TrEMBL | |
zinc_ribbon_6 | UniProtKB/TrEMBL | |
PhenoGen | Rchy1 | PhenoGen |
PROSITE | ZF_CHY | UniProtKB/TrEMBL |
ZF_CTCHY | UniProtKB/TrEMBL | |
ZF_RING_2 | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000002546 | RatGTEx |
SMART | RING | UniProtKB/TrEMBL |
Superfamily-SCOP | RING/U-box | UniProtKB/TrEMBL |
SSF161219 | UniProtKB/TrEMBL | |
SSF161245 | UniProtKB/TrEMBL | |
UniProt | A0A8I5ZWY8 | ENTREZGENE, UniProtKB/TrEMBL |
A6KKB6 | ENTREZGENE, UniProtKB/TrEMBL | |
A6KKB7 | ENTREZGENE, UniProtKB/TrEMBL | |
A6KKB8_RAT | UniProtKB/TrEMBL | |
A6KKC0 | ENTREZGENE, UniProtKB/TrEMBL | |
F7F3N3 | ENTREZGENE, UniProtKB/TrEMBL | |
Q5XIE4 | ENTREZGENE | |
UniProt Secondary | Q5XIE4 | UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2016-01-21 | Rchy1 | ring finger and CHY zinc finger domain containing 1 | Rchy1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2012-10-10 | Rchy1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | Rchy1 | ring finger and CHY zinc finger domain containing 1 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2006-03-30 | Rchy1 | ring finger and CHY zinc finger domain containing 1 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
2005-07-29 | Rchy1 | ring finger and CHY zinc finger domain containing 1 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |