Or1n1b (olfactory receptor family 1 subfamily N member 1B) - Rat Genome Database

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Gene: Or1n1b (olfactory receptor family 1 subfamily N member 1B) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or1n1b
Name: olfactory receptor family 1 subfamily N member 1B
RGD ID: 1334305
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR1N1 (olfactory receptor family 1 subfamily N member 1); INTERACTS WITH acrylamide; ammonium chloride; cadmium atom.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 416; olfactory receptor gene Olr416; olfactory receptor Olr416; Olr416; taste bud receptor protein TB 334; TB 334
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8340,835,491 - 40,836,426 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl340,835,491 - 40,836,426 (-)EnsemblGRCr8
mRatBN7.2320,444,604 - 20,445,539 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl320,442,636 - 20,448,217 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx323,512,644 - 23,513,579 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0332,097,550 - 32,098,485 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0330,322,421 - 30,323,356 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0320,913,668 - 20,914,603 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl320,913,668 - 20,914,603 (-)Ensemblrn6Rnor6.0
Rnor_5.0326,155,331 - 26,156,266 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4316,409,232 - 16,410,167 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera315,115,805 - 15,116,740 (-)NCBICelera
RGSC_v3.1316,305,603 - 16,306,539 (-)NCBI
Cytogenetic Map3p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8921883  


Genomics

Variants

.
Variants in Or1n1b
2 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:26
Count of miRNA genes:26
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000049651
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32905627547904329Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)33777225855937853Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)32862533967641995Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)33540319997383526Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)longest distance run on treadmill (CMO:0001406)3612543751125437Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)33083238444921701Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31527234860272348Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33642511681425116Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)33779691953640235Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)32267715050766390Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)33779691982796919Rat
10450811Scl73Serum cholesterol level QTL 734.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
2292615Ept17Estrogen-induced pituitary tumorigenesis QTL 176.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat
10450808Scl72Serum cholesterol level QTL 724.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33870893167641995Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)3576639050766390Rat
10450806Scl71Serum cholesterol level QTL 715.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)3290432947904329Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33870893167641995Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33870893167641995Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)336721849110333156Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)33870893167641995Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33870893167641995Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893167641995Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33870893167641995Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31141509147Rat
2325840Bp345Blood pressure QTL 3450.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)33870893183708931Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)33736373482363734Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3655634751556347Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)33610140381101403Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)32905627547904329Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)33779691947904329Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)33779691959119581Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35675975141509147Rat
1358185Ept6Estrogen-induced pituitary tumorigenesis QTL 66.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)3655634751556347Rat


Expression

RNA-SEQ Expression

circulatory system
endoderm
mesenchyme
mesoderm
renal system
reproductive system
respiratory system
4 1 5 4 1 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000049651   ⟹   ENSRNOP00000045723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl320,913,668 - 20,914,603 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119750   ⟹   ENSRNOP00000085113
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl320,442,636 - 20,448,217 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000143836   ⟹   ENSRNOP00000109660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl340,835,491 - 40,836,426 (-)Ensembl
RefSeq Acc Id: NM_001000387   ⟹   NP_001000387
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8340,835,491 - 40,836,426 (-)NCBI
mRatBN7.2320,444,604 - 20,445,539 (-)NCBI
Rnor_6.0320,913,668 - 20,914,603 (-)NCBI
Rnor_5.0326,155,331 - 26,156,266 (-)NCBI
RGSC_v3.4316,409,232 - 16,410,167 (-)RGD
Celera315,115,805 - 15,116,740 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000387 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC52909 (Get FASTA)   NCBI Sequence Viewer  
  EDL93115 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000109660
  ENSRNOP00000109660.1
RefSeq Acc Id: NP_001000387   ⟸   NM_001000387
- UniProtKB: Q62942 (UniProtKB/TrEMBL),   F1M9D5 (UniProtKB/TrEMBL),   A6JUI2 (UniProtKB/TrEMBL),   A0A8I6A383 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000045723   ⟸   ENSRNOT00000049651
Ensembl Acc Id: ENSRNOP00000085113   ⟸   ENSRNOT00000119750
Ensembl Acc Id: ENSRNOP00000109660   ⟸   ENSRNOT00000143836
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62942-F1-model_v2 AlphaFold Q62942 1-311 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334305 AgrOrtholog
BioCyc Gene G2FUF-49984 BioCyc
Ensembl Genes ENSRNOG00000029069 Ensembl
  ENSRNOG00000068962 Ensembl
  ENSRNOG00000084314 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000143836 ENTREZGENE
  ENSRNOT00000143836.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:296678 UniProtKB/TrEMBL
NCBI Gene 296678 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1n1b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029069 RatGTEx
  ENSRNOG00000068962 RatGTEx
  ENSRNOG00000084314 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6A383 ENTREZGENE, UniProtKB/TrEMBL
  A6JUI2 ENTREZGENE, UniProtKB/TrEMBL
  F1M9D5 ENTREZGENE
  Q62942 ENTREZGENE
UniProt Secondary F1M9D5 UniProtKB/TrEMBL
  Q62942 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or1n1b  olfactory receptor family 1 subfamily N member 1B  Olr416  olfactory receptor 416  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr416  olfactory receptor 416   Olr416_predicted  olfactory receptor 416 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr416_predicted  olfactory receptor 416 (predicted)      Symbol and Name status set to approved 70820 APPROVED