Or13c7e (olfactory receptor family 13 subfamily C member 7E) - Rat Genome Database

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Gene: Or13c7e (olfactory receptor family 13 subfamily C member 7E) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or13c7e
Name: olfactory receptor family 13 subfamily C member 7E
RGD ID: 1334264
Description: Predicted to enable G protein-coupled receptor activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in nucleoplasm and plasma membrane; INTERACTS WITH ammonium chloride; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 837; olfactory receptor gene Olr837; olfactory receptor Olr837; Olr837
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8562,828,302 - 62,829,249 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl562,828,302 - 62,829,249 (-)EnsemblGRCr8
mRatBN7.2558,032,535 - 58,033,482 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl558,031,445 - 58,035,562 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx560,013,100 - 60,014,047 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0561,831,909 - 61,832,856 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0561,802,529 - 61,803,476 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0559,278,263 - 59,279,210 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl559,278,263 - 59,279,210 (-)Ensemblrn6Rnor6.0
Rnor_5.0563,801,775 - 63,802,722 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4560,266,819 - 60,267,766 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera556,601,312 - 56,614,372 (-)NCBICelera
RGSC_v3.1560,266,997 - 60,267,945 (-)NCBI
Cytogenetic Map5q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or13c7e
4 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:26
Interacting mature miRNAs:27
Transcripts:ENSRNOT00000041134
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
8 2 15 31 16 24 2 9 2 6 66 41 9 12 13 38 22 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000041134   ⟹   ENSRNOP00000047260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,031,445 - 58,035,115 (-)Ensembl
Rnor_6.0 Ensembl559,278,263 - 59,279,210 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000052426   ⟹   ENSRNOP00000041214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,031,445 - 58,035,296 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106541   ⟹   ENSRNOP00000088948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,031,445 - 58,035,562 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000154349   ⟹   ENSRNOP00000111049
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl562,828,302 - 62,829,249 (-)Ensembl
RefSeq Acc Id: NM_001000897   ⟹   NP_001000897
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8562,828,302 - 62,829,249 (-)NCBI
mRatBN7.2558,032,535 - 58,033,482 (-)NCBI
Rnor_6.0559,278,263 - 59,279,210 (-)NCBI
Rnor_5.0563,801,775 - 63,802,722 (-)NCBI
RGSC_v3.4560,266,819 - 60,267,766 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000897 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC64588 (Get FASTA)   NCBI Sequence Viewer  
  EDL98774 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000111049
  ENSRNOP00000111049.1
RefSeq Acc Id: NP_001000897   ⟸   NM_001000897
- UniProtKB: G3V9G9 (UniProtKB/TrEMBL),   A6IJ54 (UniProtKB/TrEMBL),   D3ZLK0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047260   ⟸   ENSRNOT00000041134
Ensembl Acc Id: ENSRNOP00000041214   ⟸   ENSRNOT00000052426
Ensembl Acc Id: ENSRNOP00000088948   ⟸   ENSRNOT00000106541
Ensembl Acc Id: ENSRNOP00000111049   ⟸   ENSRNOT00000154349
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V9G9-F1-model_v2 AlphaFold G3V9G9 1-315 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334264 AgrOrtholog
BioCyc Gene G2FUF-41486 BioCyc
Ensembl Genes ENSRNOG00000033505 Ensembl
  ENSRNOG00000065792 Ensembl
  ENSRNOG00000089753 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000154349 ENTREZGENE
  ENSRNOT00000154349.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405207 UniProtKB/TrEMBL
NCBI Gene 405207 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or13c7e PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000033505 RatGTEx
  ENSRNOG00000065792 RatGTEx
  ENSRNOG00000089753 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6IJ54 ENTREZGENE, UniProtKB/TrEMBL
  D3ZLK0 ENTREZGENE, UniProtKB/TrEMBL
  G3V9G9 ENTREZGENE
UniProt Secondary G3V9G9 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or13c7e  olfactory receptor family 13 subfamily C member 7E  Olr837  olfactory receptor 837  Symbol and Name Changed 1299863 APPROVED
2005-12-06 Olr837  olfactory receptor 837  Olr837_predicted  olfactory receptor 837 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-02-04 Olr837_predicted  olfactory receptor 837 (predicted)      Symbol and Name status set to approved 70820 APPROVED