Or10al27 (olfactory receptor family 10 subfamily AL member 27) - Rat Genome Database

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Gene: Or10al27 (olfactory receptor family 10 subfamily AL member 27) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or10al27
Name: olfactory receptor family 10 subfamily AL member 27
RGD ID: 1334132
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane; INTERACTS WITH benomyl; cadmium dichloride; DDE.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC103689944; olfactory receptor 10C1-like; olfactory receptor 1700; olfactory receptor gene Olr1700; olfactory receptor Olr1700; olfactory receptor-like protein; Olr1700; SCR D-7; seven transmembrane domain odorant receptor-like protein
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr820794,490 - 795,491 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl20743,522 - 816,076 (-)EnsemblGRCr8
mRatBN7.220789,272 - 790,237 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl20761,025 - 765,744 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl20734,965 - 811,125 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx20796,365 - 797,330 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.020799,823 - 800,788 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.020723,098 - 724,063 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,089,163 - 1,090,128 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,098,343 - 1,099,336 (-)Ensemblrn6Rnor6.0
Rnor_5.020964,117 - 964,926 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.0201,086,065 - 1,087,030 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.420747,810 - 748,775 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera201,557,017 - 1,557,871 (-)NCBICelera
RGSC_v3.120747,809 - 748,775 (-)NCBI
Cytogenetic Map20p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
benomyl  (EXP)
cadmium dichloride  (EXP)
DDE  (EXP)
DDT  (EXP)
flutamide  (EXP)
thioacetamide  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9545261  


Genomics

Variants

.
Variants in Or10al27
18 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2016693431Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2016693431Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013629303Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
1 1 1 2 4 7 1 3 1 1 9 4 1 2 20 6

Sequence


Ensembl Acc Id: ENSRNOT00000071766   ⟹   ENSRNOP00000066650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl201,098,343 - 1,099,336 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114598   ⟹   ENSRNOP00000085963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20761,025 - 765,744 (-)Ensembl
RefSeq Acc Id: NM_001001113   ⟹   NP_001001113
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr820794,526 - 795,491 (-)NCBI
mRatBN7.220789,272 - 790,237 (-)NCBI
Rnor_6.0201,089,163 - 1,090,128 (-)NCBI
Rnor_5.0201,086,065 - 1,087,030 (-)NCBI
RGSC_v3.420747,810 - 748,775 (-)RGD
Celera201,557,017 - 1,566,949 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039098923   ⟹   XP_038954851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr820794,490 - 795,491 (-)NCBI
mRatBN7.220789,272 - 790,237 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001001113 (Get FASTA)   NCBI Sequence Viewer  
  XP_038954851 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC17224 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063503.4
RefSeq Acc Id: NP_001001113   ⟸   NM_001001113
- UniProtKB: O70268 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066650   ⟸   ENSRNOT00000071766
RefSeq Acc Id: XP_038954851   ⟸   XM_039098923
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000085963   ⟸   ENSRNOT00000114598
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RAU1-F1-model_v2 AlphaFold M0RAU1 1-321 view protein structure
AF-G3V9Z0-F1-model_v2 AlphaFold G3V9Z0 1-342 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334132 AgrOrtholog
BioCyc Gene G2FUF-5056 BioCyc
Ensembl Genes ENSRNOG00000046355 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000050316 Ensembl
Ensembl Transcript ENSRNOT00000066600.5 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene 406012 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or10al27 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046355 RatGTEx
  ENSRNOG00000050316 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt G3V9Z0_RAT UniProtKB/TrEMBL
  O70268 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-15 Or10al27  olfactory receptor family 10 subfamily AL member 27  Olr1700  olfactory receptor 1700  Name and Symbol changed 629549 APPROVED
2021-03-09 Olr1700  olfactory receptor 1700  LOC103689944  olfactory receptor 10C1-like  Data merged from RGD:9269809 737654 PROVISIONAL
2014-08-25 LOC103689944  olfactory receptor 10C1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1700  olfactory receptor 1700   Olr1700_predicted  olfactory receptor 1700 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1700_predicted  olfactory receptor 1700 (predicted)      Symbol and Name status set to approved 70820 APPROVED