Or5v1b (olfactory receptor family 5 subfamily V member 1B) - Rat Genome Database

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Pathways
Gene: Or5v1b (olfactory receptor family 5 subfamily V member 1B) Rattus norvegicus
Analyze
Symbol: Or5v1b
Name: olfactory receptor family 5 subfamily V member 1B
RGD ID: 1334062
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR5V1 (olfactory receptor family 5 subfamily V member 1); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); arsane (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: MOR249-2; olfactory receptor 1730; olfactory receptor 30; Olr1730; Or30; ratchr20-1246310-1247263_ORF
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,163,321 - 1,164,274 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl201,163,321 - 1,164,274 (+)EnsemblGRCr8
mRatBN7.2201,158,073 - 1,159,026 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,151,540 - 1,159,222 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx201,193,522 - 1,194,475 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,197,008 - 1,197,961 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,153,628 - 1,154,581 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,647,469 - 1,648,422 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,647,441 - 1,648,449 (+)Ensemblrn6Rnor6.0
Rnor_5.0203,692,456 - 3,693,409 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4201,246,310 - 1,247,263 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera201,891,645 - 1,892,598 (+)NCBICelera
RGSC_v3.1201,246,309 - 1,247,258 (+)NCBI
Cytogenetic Map20p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, etal., Genome Res 2004 Apr;14(4):631-9.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or5v1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8201,163,321 - 1,164,274 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl201,163,321 - 1,164,274 (+)EnsemblGRCr8
mRatBN7.2201,158,073 - 1,159,026 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl201,151,540 - 1,159,222 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx201,193,522 - 1,194,475 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0201,197,008 - 1,197,961 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0201,153,628 - 1,154,581 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0201,647,469 - 1,648,422 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl201,647,441 - 1,648,449 (+)Ensemblrn6Rnor6.0
Rnor_5.0203,692,456 - 3,693,409 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4201,246,310 - 1,247,263 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera201,891,645 - 1,892,598 (+)NCBICelera
RGSC_v3.1201,246,309 - 1,247,258 (+)NCBI
Cytogenetic Map20p12NCBI
OR5V1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,353,749 - 29,368,865 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,353,749 - 29,431,967 (-)Ensemblhg38GRCh38
GRCh37629,321,526 - 29,336,642 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,430,986 - 29,432,033 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34629,430,985 - 29,432,033NCBI
Celera630,929,186 - 30,930,233 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef629,130,619 - 29,131,666 (-)NCBIHuRef
CHM1_1629,325,270 - 29,326,317 (-)NCBICHM1_1
T2T-CHM13v2.0629,228,525 - 29,243,652 (-)NCBIT2T-CHM13v2.0
Or5v1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391737,815,851 - 37,844,816 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1737,818,921 - 37,843,340 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381737,525,753 - 37,537,652 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1737,508,030 - 37,532,449 (+)Ensemblmm10GRCm38
MGSCv371737,666,902 - 37,667,942 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361737,138,032 - 37,138,985 (+)NCBIMGSCv36mm8
Celera1740,971,961 - 40,973,001 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1719.16NCBI
LOC100972682
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2543,986,009 - 44,000,824 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1639,950,375 - 39,965,190 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0629,173,223 - 29,174,264 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1629,831,339 - 29,832,380 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl629,831,339 - 29,832,304 (-)EnsemblpanPan2panpan1.1
OR13L2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11757,996,386 - 57,997,345 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1757,996,386 - 57,997,345 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1757,464,971 - 57,465,930 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01758,999,636 - 59,000,595 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1758,999,636 - 59,000,595 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11757,873,332 - 57,874,291 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01757,926,669 - 57,927,628 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01758,653,284 - 58,654,243 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC100152520
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.2725,794,642 - 25,795,595 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103221889
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11743,228,075 - 43,231,547 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1743,228,604 - 43,229,566 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604429,006,036 - 29,009,081 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Or5v1b
4 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61474Eae1Experimental allergic encephalomyelitis QTL 13nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)2016693431Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2016693431Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013629303Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
23 17 8 2 10 2 1 31 15 17 14 26 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000000986   ⟹   ENSRNOP00000000986
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl20964,172 - 965,125 (-)Ensembl
Rnor_6.0 Ensembl201,647,441 - 1,648,449 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000108245   ⟹   ENSRNOP00000085660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl201,163,321 - 1,164,274 (+)Ensembl
mRatBN7.2 Ensembl201,151,540 - 1,159,222 (+)Ensembl
RefSeq Acc Id: NM_001000279   ⟹   NP_001000279
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8201,163,321 - 1,164,274 (+)NCBI
mRatBN7.2201,158,073 - 1,159,026 (+)NCBI
Rnor_6.0201,647,469 - 1,648,422 (+)NCBI
Rnor_5.0203,692,456 - 3,693,409 (+)NCBI
RGSC_v3.4201,246,310 - 1,247,263 (+)RGD
Celera201,891,645 - 1,892,598 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000279 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000085660
  ENSRNOP00000085660.1
RefSeq Acc Id: NP_001000279   ⟸   NM_001000279
- UniProtKB: A0A8I6A2T4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000000986   ⟸   ENSRNOT00000000986
Ensembl Acc Id: ENSRNOP00000085660   ⟸   ENSRNOT00000108245
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334062 AgrOrtholog
BioCyc Gene G2FUF-5018 BioCyc
Ensembl Genes ENSRNOG00000000759 Ensembl
  ENSRNOG00000065028 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000108245 ENTREZGENE
  ENSRNOT00000108245.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_GPCR UniProtKB/TrEMBL
KEGG Report rno:294187 UniProtKB/TrEMBL
NCBI Gene 294187 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or5v1b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000759 RatGTEx
  ENSRNOG00000065028 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6A2T4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or5v1b  olfactory receptor family 5 subfamily V member 1B  Olr1730  olfactory receptor 1730  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1730  olfactory receptor 1730   Olr1730_predicted  olfactory receptor 1730 (predicted)  'predicted' is removed 2292626 APPROVED
2005-03-02 Olr1730_predicted  olfactory receptor 1730 (predicted)  Or30  olfactory receptor 30  Symbol and Name status set to approved 737654 APPROVED
2005-02-14 Or30  olfactory receptor 30      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-02-04 Olr1730_predicted  olfactory receptor 1730 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL