Or7h7b (olfactory receptor family 7 subfamily H member 7B) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Or7h7b (olfactory receptor family 7 subfamily H member 7B) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or7h7b
Name: olfactory receptor family 7 subfamily H member 7B
RGD ID: 1333761
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane; INTERACTS WITH ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1193; olfactory receptor gene Olr1193; olfactory receptor Olr1193; Olr1193
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,136,138 - 27,137,100 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl827,136,138 - 27,137,100 (-)EnsemblGRCr8
mRatBN7.2818,859,888 - 18,860,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl818,859,888 - 18,860,850 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx822,874,546 - 22,875,508 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,172,385 - 21,173,347 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,089,618 - 19,090,580 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,305,250 - 21,306,212 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,305,250 - 21,306,212 (+)Ensemblrn6Rnor6.0
Rnor_5.0821,367,597 - 21,368,559 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4819,330,568 - 19,331,530 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera820,267,165 - 20,268,127 (-)NCBICelera
RGSC_v3.1819,330,567 - 19,331,530 (-)NCBI
Cytogenetic Map8q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or7h7b
1 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:15
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000050206
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8132882639Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat


Expression

RNA-SEQ Expression

appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
6 16 82 11 13 3 10 3 2 57 29 80 19 33 10 6 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001000594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000050206   ⟹   ENSRNOP00000063746
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl827,136,138 - 27,137,100 (-)Ensembl
mRatBN7.2 Ensembl818,859,888 - 18,860,850 (-)Ensembl
Rnor_6.0 Ensembl821,305,250 - 21,306,212 (+)Ensembl
RefSeq Acc Id: NM_001000594   ⟹   NP_001000594
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,136,138 - 27,137,100 (-)NCBI
mRatBN7.2818,859,888 - 18,860,850 (-)NCBI
Rnor_6.0821,305,250 - 21,306,212 (+)NCBI
Rnor_5.0821,367,597 - 21,368,559 (+)NCBI
RGSC_v3.4819,330,568 - 19,331,530 (-)RGD
Celera820,267,165 - 20,268,127 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000594 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063746
  ENSRNOP00000063746.1
  ENSRNOP00000080888.2
RefSeq Acc Id: NP_001000594   ⟸   NM_001000594
- UniProtKB: D3ZR67 (UniProtKB/TrEMBL),   A0A8I6G591 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063746   ⟸   ENSRNOT00000050206
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZR67-F1-model_v2 AlphaFold D3ZR67 1-320 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333761 AgrOrtholog
BioCyc Gene G2FUF-31479 BioCyc
Ensembl Genes ENSRNOG00000028864 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000087058 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050206 ENTREZGENE
  ENSRNOT00000050206.4 UniProtKB/TrEMBL
  ENSRNOT00000097492.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:367032 UniProtKB/TrEMBL
NCBI Gene 367032 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or7h7b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028864 RatGTEx
  ENSRNOG00000087058 RatGTEx
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I6G591 ENTREZGENE, UniProtKB/TrEMBL
  D3ZR67 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or7h7b  olfactory receptor family 7 subfamily H member 7B  Olr1193  olfactory receptor 1193  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1193  olfactory receptor 1193   Olr1193_predicted  olfactory receptor 1193 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1193_predicted  olfactory receptor 1193 (predicted)      Symbol and Name status set to approved 70820 APPROVED