Or7a37 (olfactory receptor family 7 subfamily A member 37) - Rat Genome Database

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Gene: Or7a37 (olfactory receptor family 7 subfamily A member 37) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or7a37
Name: olfactory receptor family 7 subfamily A member 37
RGD ID: 1333657
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR7A2P (olfactory receptor family 7 subfamily A member 2 pseudogene); INTERACTS WITH ammonium chloride; bisphenol A; cadmium dichloride.
Type: protein-coding (Ensembl: pseudogene)
RefSeq Status: VALIDATED
Previously known as: olfactory receptor 1078; olfactory receptor-like protein F3; Olr1078; ratchr7-12106889-12105960_ORF
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,228,606 - 11,229,607 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl711,228,606 - 11,229,607 (-)EnsemblGRCr8
mRatBN7.2710,578,008 - 10,579,009 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,577,151 - 10,592,390 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx713,444,438 - 13,445,439 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,321,882 - 15,322,883 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,165,680 - 13,166,681 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,466,347 - 13,492,277 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,466,347 - 13,467,348 (-)Ensemblrn6Rnor6.0
Rnor_5.0713,670,274 - 13,671,275 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4712,105,888 - 12,106,889 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera78,717,866 - 8,718,867 (-)NCBICelera
RGSC_v3.1712,105,887 - 12,106,889 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Buck L and Axel R, Cell 1991 Apr 5;65(1):175-87.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or7a37
1 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)71051708662346019Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)71011291660150541Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7946087754460877Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
1300138Hrtrt9Heart rate QTL 94.72heart pumping trait (VT:2000009)heart rate (CMO:0000002)71049882055498820Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat


Expression

RNA-SEQ Expression

circulatory system
ectoderm
mesenchyme
mesoderm
nervous system
renal system
reproductive system
sensory system
visual system
2 3 6 2 3 4 3 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000083574   ⟹   ENSRNOP00000074563
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl710,577,151 - 10,592,390 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl713,466,347 - 13,467,348 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000149271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl711,228,606 - 11,229,607 (-)Ensembl
RefSeq Acc Id: NM_207597   ⟹   NP_997480
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8711,228,606 - 11,229,607 (-)NCBI
mRatBN7.2710,578,008 - 10,579,009 (-)NCBI
Rnor_6.0713,466,347 - 13,467,348 (-)NCBI
Rnor_5.0713,670,274 - 13,671,275 (-)NCBI
RGSC_v3.4712,105,888 - 12,106,889 (-)RGD
Celera78,717,866 - 8,718,867 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_997480 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41739 (Get FASTA)   NCBI Sequence Viewer  
  EDL89440 (Get FASTA)   NCBI Sequence Viewer  
  P23265 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_997480   ⟸   NM_207597
- UniProtKB: P23265 (UniProtKB/Swiss-Prot),   A0A0G2K8D3 (UniProtKB/TrEMBL),   A6K920 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074563   ⟸   ENSRNOT00000083574
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P23265-F1-model_v2 AlphaFold P23265 1-333 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333657 AgrOrtholog
BioCyc Gene G2FUF-34858 BioCyc
Ensembl Genes ENSRNOG00000059517 Ensembl
  ENSRNOG00000062310 Ensembl
  ENSRNOG00000074319 Ensembl
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Olfact_rcpt UniProtKB/Swiss-Prot
KEGG Report rno:299593 UniProtKB/Swiss-Prot
NCBI Gene 299593 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/Swiss-Prot
Pfam 7tm_4 UniProtKB/Swiss-Prot
PhenoGen Or7a37 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  OLFACTORYR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000059517 RatGTEx
  ENSRNOG00000062310 RatGTEx
  ENSRNOG00000074319 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A0A0G2K8D3 ENTREZGENE
  A6K920 ENTREZGENE, UniProtKB/TrEMBL
  O1078_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or7a37  olfactory receptor family 7 subfamily A member 37  Olr1078  olfactory receptor 1078  Symbol and Name Changed 1299863 APPROVED
2005-02-04 Olr1078  olfactory receptor 1078      Symbol and Name status set to approved 70820 APPROVED