Or10w1 (olfactory receptor family 10 subfamily W member 1) - Rat Genome Database

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Gene: Or10w1 (olfactory receptor family 10 subfamily W member 1) Rattus norvegicus
Analyze
Symbol: Or10w1
Name: olfactory receptor family 10 subfamily W member 1
RGD ID: 1333289
Description: Predicted to enable odorant binding activity and olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR10W1 (olfactory receptor family 10 subfamily W member 1); INTERACTS WITH bisphenol A; benzo[a]pyrene (ortholog); crocidolite asbestos (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 372; olfactory receptor gene Olr372; olfactory receptor Olr372; Olr372
RGD Orthologs
Human
Mouse
Bonobo
Dog
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81220,231,270 - 220,232,220 (+)NCBIGRCr8
mRatBN7.21210,806,724 - 210,807,674 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,806,709 - 210,807,674 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1219,181,115 - 219,182,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01226,072,376 - 226,073,326 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01218,935,595 - 218,936,545 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,521,485 - 230,522,435 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,521,485 - 230,522,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01237,660,221 - 237,661,171 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41216,770,361 - 216,771,311 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11216,928,790 - 216,929,741 (+)NCBI
Celera1208,205,389 - 208,206,339 (+)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or10w1Ratintellectual disability  ISOOR10W1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or10w1Ratbenzo[a]pyrene increases methylationISOOR10W1 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of OR10W1 exonCTDPMID:27901495
Or10w1Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of OR10W1 mRNACTDPMID:25181051
Or10w1Ratcrocidolite asbestos decreases expressionISOOr10w1 (Mus musculus)6480464Asbestos and Crocidolite results in decreased expression of OR10W1 mRNACTDPMID:23917077
Or10w1Ratsodium arsenite decreases expressionISOOR10W1 (Homo sapiens)6480464sodium arsenite results in decreased expression of OR10W1 mRNACTDPMID:25879800


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or10w1Ratdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Or10w1Ratdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or10w1RatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or10w1RatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or10w1RatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276 and InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or10w1Ratsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or10w1Ratsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or10w1Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or10w1Ratmembrane located_inIEAInterPro:IPR000276 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Or10w1Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
Or10w1Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or10w1RatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or10w1RatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or10w1Ratodorant binding enablesIBAMGI:3030853 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or10w1Ratolfactory receptor activity enablesIBAMGI:3030069 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Or10w1Ratolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or10w1Ratolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or10w1Rattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


Or10w1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81220,231,270 - 220,232,220 (+)NCBIGRCr8
mRatBN7.21210,806,724 - 210,807,674 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1210,806,709 - 210,807,674 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1219,181,115 - 219,182,065 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01226,072,376 - 226,073,326 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01218,935,595 - 218,936,545 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01230,521,485 - 230,522,435 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1230,521,485 - 230,522,435 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01237,660,221 - 237,661,171 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41216,770,361 - 216,771,311 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11216,928,790 - 216,929,741 (+)NCBI
Celera1208,205,389 - 208,206,339 (+)NCBICelera
Cytogenetic Map1q43NCBI
OR10W1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,266,792 - 58,268,260 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,266,792 - 58,268,260 (-)EnsemblGRCh38hg38GRCh38
GRCh371158,034,264 - 58,035,732 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,790,840 - 57,792,308 (-)NCBINCBI36Build 36hg18NCBI36
Celera1155,392,678 - 55,394,146 (-)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1154,382,049 - 54,383,517 (-)NCBIHuRef
CHM1_11157,900,236 - 57,901,704 (-)NCBICHM1_1
T2T-CHM13v2.01158,216,198 - 58,217,666 (-)NCBIT2T-CHM13v2.0
Or10w1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391913,631,810 - 13,632,760 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1913,628,455 - 13,636,909 (+)EnsemblGRCm39 Ensembl
GRCm381913,654,446 - 13,655,396 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1913,651,091 - 13,659,545 (+)EnsemblGRCm38mm10GRCm38
MGSCv371913,728,936 - 13,729,886 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361913,721,465 - 13,722,415 (+)NCBIMGSCv36mm8
Celera1914,325,582 - 14,326,532 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map198.75NCBI
LOC100983484
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2959,416,225 - 59,417,693 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11160,442,347 - 60,443,815 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01153,506,860 - 53,508,316 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11156,969,864 - 56,971,320 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1156,970,007 - 56,970,924 (-)Ensemblpanpan1.1panPan2
OR10W1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,111,132 - 38,112,049 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,111,132 - 38,112,049 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1837,655,401 - 37,656,345 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01838,785,739 - 38,786,683 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1838,785,766 - 38,786,683 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11838,369,614 - 38,370,558 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01837,942,141 - 37,943,085 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01838,569,315 - 38,570,259 (+)NCBIUU_Cfam_GSD_1.0
LOC103235140
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,011,517 - 15,014,121 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl115,012,923 - 15,013,837 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038112,335,726 - 112,337,362 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.

.
Variants in Or10w1
7 total Variants

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:23
Interacting mature miRNAs:23
Transcripts:ENSRNOT00000047374
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 92 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8693637Alc29Alcohol consumption QTL 292.70.258drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)1207987464234238494Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat

1 to 10 of 92 rows





RefSeq Transcripts NM_001001048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000017572   ⟹   ENSRNOP00000017572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1210,806,709 - 210,807,674 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000047374   ⟹   ENSRNOP00000040506
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1230,521,485 - 230,522,435 (+)Ensembl
RefSeq Acc Id: NM_001001048   ⟹   NP_001001048
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81220,231,270 - 220,232,220 (+)NCBI
mRatBN7.21210,806,724 - 210,807,674 (+)NCBI
Rnor_6.01230,521,485 - 230,522,435 (+)NCBI
Rnor_5.01237,660,221 - 237,661,171 (+)NCBI
RGSC_v3.41216,770,361 - 216,771,311 (+)RGD
Celera1208,205,389 - 208,206,339 (+)RGD
Sequence:
Protein RefSeqs NP_001001048 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM12943 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017572
  ENSRNOP00000017572.4
RefSeq Acc Id: NP_001001048   ⟸   NM_001001048
- UniProtKB: D3ZE76 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000040506   ⟸   ENSRNOT00000047374
Ensembl Acc Id: ENSRNOP00000017572   ⟸   ENSRNOT00000017572
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-D4AA57-F1-model_v2 AlphaFold D4AA57 1-316 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 21 of 21 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-56247 BioCyc
Ensembl Genes ENSRNOG00000047343 Ensembl
  ENSRNOG00000063952 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017572 ENTREZGENE
  ENSRNOT00000017572.5 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene 405934 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or10w1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047343 RatGTEx
  ENSRNOG00000063952 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt D3ZE76 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or10w1  olfactory receptor family 10 subfamily W member 1  Olr372  olfactory receptor 372  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr372  olfactory receptor 372   Olr372_predicted  olfactory receptor 372 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr372_predicted  olfactory receptor 372 (predicted)      Symbol and Name status set to approved 70820 APPROVED