Or51b4b (olfactory receptor family 51 subfamily B member 4B) - Rat Genome Database

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Gene: Or51b4b (olfactory receptor family 51 subfamily B member 4B) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or51b4b
Name: olfactory receptor family 51 subfamily B member 4B
RGD ID: 1332980
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be active in plasma membrane. Orthologous to human OR51B4 (olfactory receptor family 51 subfamily B member 4); INTERACTS WITH 17beta-estradiol; bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 129; olfactory receptor gene Olr129; olfactory receptor Olr129; Olr129
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81167,720,537 - 167,721,472 (-)NCBIGRCr8
mRatBN7.21158,308,648 - 158,309,583 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1158,308,648 - 158,309,583 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1166,313,300 - 166,314,235 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01173,493,311 - 173,494,246 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,381,507 - 166,382,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01169,031,222 - 169,032,157 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1169,031,222 - 169,032,157 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01175,193,580 - 175,194,515 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41161,677,418 - 161,678,353 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11161,758,707 - 161,759,643 (-)NCBI
Celera1156,319,444 - 156,320,379 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51b4bRat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in increased expression of OR51B4B mRNACTDPMID:26496021
Or51b4bRatbisphenol A multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in increased expression of OR51B4B mRNACTDPMID:26496021


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51b4bRatdetection of chemical stimulus involved in sensory perception of smell  IEARGD:51314831303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or51b4bRatdetection of chemical stimulus involved in sensory perception of smell involved_inIEAGO:00049841600115GO_REF:0000108GOCGO_REF:0000108
Or51b4bRatG protein-coupled receptor signaling pathway  IEARGD:51314831303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or51b4bRatG protein-coupled receptor signaling pathway involved_inIEAInterPro:IPR000276|InterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or51b4bRatG protein-coupled receptor signaling pathway involved_inIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or51b4bRatsensory perception of smell involved_inIEAUniProtKB-KW:KW-05521600115GO_REF:0000043UniProtGO_REF:0000043
Or51b4bRatsignal transduction involved_inIEAUniProtKB-KW:KW-08071600115GO_REF:0000043UniProtGO_REF:0000043

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51b4bRatmembrane located_inIEAInterPro:IPR000276|InterPro:IPR000725|InterPro:IPR0174521600115GO_REF:0000002InterProGO_REF:0000002
Or51b4bRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Or51b4bRatmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Or51b4bRatplasma membrane is_active_inIBAMGI:2157548|PANTHER:PTN002816874|UniProtKB:Q9H2551600115GO_REF:0000033GO_CentralGO_REF:0000033
Or51b4bRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Or51b4bRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51b4bRatG protein-coupled receptor activity enablesIEAUniProtKB-KW:KW-02971600115GO_REF:0000043UniProtGO_REF:0000043
Or51b4bRatG protein-coupled receptor activity enablesIEAInterPro:IPR0002761600115GO_REF:0000002InterProGO_REF:0000002
Or51b4bRatolfactory receptor activity  IEARGD:51314831303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or51b4bRatolfactory receptor activity enablesIEAInterPro:IPR0007251600115GO_REF:0000002InterProGO_REF:0000002
Or51b4bRatolfactory receptor activity enablesIBAPANTHER:PTN002816874|UniProtKB:Q9H2551600115GO_REF:0000033GO_CentralGO_REF:0000033

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or51b4bRattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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Variants in Or51b4b
12 total Variants

Predicted Target Of
Summary Value
Count of predictions:86
Count of miRNA genes:62
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000034624
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 78 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
4889419Cstrr2Cold stress response QTL 20.05urine catecholamine amount (VT:0010502)absolute change in urine norepinephrine level (CMO:0001634)1155866514158592016Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat

1 to 10 of 78 rows



reproductive system
4


RefSeq Transcripts NM_001001027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC113925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000034624   ⟹   ENSRNOP00000031107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,308,648 - 158,309,583 (-)Ensembl
Rnor_6.0 Ensembl1169,031,222 - 169,032,157 (-)Ensembl
RefSeq Acc Id: NM_001001027   ⟹   NP_001001027
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,720,537 - 167,721,472 (-)NCBI
mRatBN7.21158,308,648 - 158,309,583 (-)NCBI
Rnor_6.01169,031,222 - 169,032,157 (-)NCBI
Rnor_5.01175,193,580 - 175,194,515 (-)NCBI
RGSC_v3.41161,677,418 - 161,678,353 (-)RGD
Celera1156,319,444 - 156,320,379 (-)RGD
Sequence:
Protein RefSeqs NP_001001027 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000031107
  ENSRNOP00000031107.2
RefSeq Acc Id: NP_001001027   ⟸   NM_001001027
- UniProtKB: D3ZFT4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000031107   ⟸   ENSRNOT00000034624
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZFT4-F1-model_v2 AlphaFold D3ZFT4 1-311 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-58128 BioCyc
Ensembl Genes ENSRNOG00000025163 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000034624 ENTREZGENE
  ENSRNOT00000034624.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfactory_rcpt UniProtKB/TrEMBL
KEGG Report rno:405912 UniProtKB/TrEMBL
NCBI Gene 405912 ENTREZGENE
PANTHER OLFACTORY RECEPTOR 51B4 UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 56B1-RELATED UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or51b4b PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025163 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt D3ZFT4 ENTREZGENE, UniProtKB/TrEMBL
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or51b4b  olfactory receptor family 51 subfamily B member 4B  Olr129  olfactory receptor 129  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr129  olfactory receptor 129   Olr129_predicted  olfactory receptor 129 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr129_predicted  olfactory receptor 129 (predicted)      Symbol and Name status set to approved 70820 APPROVED