Or6c212 (olfactory receptor family 6 subfamily C member 212) - Rat Genome Database

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Gene: Or6c212 (olfactory receptor family 6 subfamily C member 212) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or6c212
Name: olfactory receptor family 6 subfamily C member 212
RGD ID: 1332976
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane; INTERACTS WITH bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 950; olfactory receptor gene Olr950; olfactory receptor Olr950; Olr950
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr874,221,265 - 4,222,242 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl74,221,265 - 4,222,242 (+)EnsemblGRCr8
mRatBN7.273,572,252 - 3,573,229 (+)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx76,400,269 - 6,401,246 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.078,275,951 - 8,276,928 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
Rnor_6.077,616,522 - 7,617,499 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl77,616,522 - 7,617,499 (-)Ensemblrn6Rnor6.0
Rnor_5.077,719,276 - 7,720,253 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.474,838,935 - 4,839,912NCBIRGSC_v3.4RGSC_v3.4rn4
RGSC_v3.174,838,934 - 4,839,912NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or6c212
5 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:88
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000051053
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat


Expression

RNA-SEQ Expression

endocrine system
endoderm
exocrine system
hepatobiliary system
mesenchyme
renal system
reproductive system
respiratory system
1 2 1 1 2 1 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001001370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000051053   ⟹   ENSRNOP00000050931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl77,616,522 - 7,617,499 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097539   ⟹   ENSRNOP00000080967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl74,221,265 - 4,222,242 (+)Ensembl
RefSeq Acc Id: NM_001001370   ⟹   NP_001001370
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr874,221,265 - 4,222,242 (+)NCBI
mRatBN7.273,572,252 - 3,573,229 (+)NCBI
Rnor_6.077,616,522 - 7,617,499 (-)NCBI
Rnor_5.077,719,276 - 7,720,253 (-)NCBI
RGSC_v3.474,838,935 - 4,839,912 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001001370 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000080967
RefSeq Acc Id: NP_001001370   ⟸   NM_001001370
- UniProtKB: D3ZG09 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000050931   ⟸   ENSRNOT00000051053
Ensembl Acc Id: ENSRNOP00000080967   ⟸   ENSRNOT00000097539

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZG09-F1-model_v2 AlphaFold D3ZG09 1-325 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1332976 AgrOrtholog
BioCyc Gene G2FUF-35230 BioCyc
Ensembl Genes ENSRNOG00000032325 Ensembl
  ENSRNOG00000078286 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000097539 ENTREZGENE
NCBI Gene 288878 ENTREZGENE
PhenoGen Or6c212 PhenoGen
RatGTEx ENSRNOG00000032325 RatGTEx
  ENSRNOG00000078286 RatGTEx
UniProt D3ZG09 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or6c212  olfactory receptor family 6 subfamily C member 212  Olr950  olfactory receptor 950  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr950  olfactory receptor 950   Olr950_predicted  olfactory receptor 950 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr950_predicted  olfactory receptor 950 (predicted)      Symbol and Name status set to approved 70820 APPROVED