Or1f19e (olfactory receptor family 1 subfamily F member 19E) - Rat Genome Database

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Gene: Or1f19e (olfactory receptor family 1 subfamily F member 19E) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or1f19e
Name: olfactory receptor family 1 subfamily F member 19E
RGD ID: 1332925
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR1F1 (olfactory receptor family 1 subfamily F member 1); INTERACTS WITH ammonium chloride; cadmium dichloride.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1370; olfactory receptor gene Olr1370; olfactory receptor Olr1370; Olr1370
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81012,686,666 - 12,687,607 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1012,686,666 - 12,687,607 (-)EnsemblGRCr8
mRatBN7.21012,182,022 - 12,182,963 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,182,022 - 12,182,963 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1016,871,654 - 16,872,595 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01016,360,462 - 16,361,403 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01011,908,952 - 11,909,893 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01012,521,289 - 12,522,230 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1012,521,289 - 12,522,230 (-)Ensemblrn6Rnor6.0
Rnor_5.01012,346,086 - 12,347,027 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41012,388,787 - 12,389,728 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1011,907,713 - 11,908,654 (-)NCBICelera
RGSC_v3.11012,388,786 - 12,389,728 (-)NCBI
Cytogenetic Map10q12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:6
Count of miRNA genes:6
Interacting mature miRNAs:6
Transcripts:ENSRNOT00000073401
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10666111835509383Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10666092373950353Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10589381150893811Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10125055464349221Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10589381150893811Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10687714251877142Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135730538Rat
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10130004247Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10589381150893811Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10686461896620484Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1092219745922197Rat
2317754Glom25Glomerulus QTL 253.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)10210370847103708Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10589381150893811Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10117749933Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138832698Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
hemolymphoid system
mesenchyme
mesoderm
renal system
reproductive system
1 1 1 6 1 3 5

Sequence


Ensembl Acc Id: ENSRNOT00000073401   ⟹   ENSRNOP00000064440
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1012,686,666 - 12,687,607 (-)Ensembl
mRatBN7.2 Ensembl1012,182,022 - 12,182,963 (-)Ensembl
Rnor_6.0 Ensembl1012,521,289 - 12,522,230 (-)Ensembl
RefSeq Acc Id: NM_001000979   ⟹   NP_001000979
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81012,686,666 - 12,687,607 (-)NCBI
mRatBN7.21012,182,022 - 12,182,963 (-)NCBI
Rnor_6.01012,521,289 - 12,522,230 (-)NCBI
Rnor_5.01012,346,086 - 12,347,027 (-)NCBI
RGSC_v3.41012,388,787 - 12,389,728 (-)RGD
Celera1011,907,713 - 11,908,654 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000979 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC64597 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064440
  ENSRNOP00000064440.1
RefSeq Acc Id: NP_001000979   ⟸   NM_001000979
- UniProtKB: M0R4Y8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064440   ⟸   ENSRNOT00000073401
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R4Y8-F1-model_v2 AlphaFold M0R4Y8 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1332925 AgrOrtholog
BioCyc Gene G2FUF-25967 BioCyc
Ensembl Genes ENSRNOG00000046347 Ensembl
  ENSRNOG00000069687 Ensembl
  ENSRNOG00000074334 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000073401 ENTREZGENE
  ENSRNOT00000073401.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:405334 UniProtKB/TrEMBL
NCBI Gene 405334 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or1f19e PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046347 RatGTEx
  ENSRNOG00000069687 RatGTEx
  ENSRNOG00000074334 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt M0R4Y8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or1f19e  olfactory receptor family 1 subfamily F member 19E  Olr1370  olfactory receptor 1370  Symbol and Name Changed 1299863 APPROVED
2005-12-06 Olr1370  olfactory receptor 1370  Olr1370_predicted  olfactory receptor 1370 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-02-04 Olr1370_predicted  olfactory receptor 1370 (predicted)      Symbol and Name status set to approved 70820 APPROVED