Or6c3d (olfactory receptor family 6 subfamily C member 3D) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Or6c3d (olfactory receptor family 6 subfamily C member 3D) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or6c3d
Name: olfactory receptor family 6 subfamily C member 3D
RGD ID: 1332890
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in plasma membrane. Orthologous to human OR6C3 (olfactory receptor family 6 subfamily C member 3); INTERACTS WITH atrazine.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 894; olfactory receptor gene Olr894; olfactory receptor Olr894; Olr894
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr872,754,897 - 2,755,832 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl72,754,897 - 2,755,832 (+)EnsemblGRCr8
mRatBN7.272,126,405 - 2,127,340 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl74,540,253 - 4,542,686 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl72,126,405 - 2,127,340 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx74,952,882 - 4,953,817 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.076,828,551 - 6,829,486 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.077,112,949 - 7,113,884 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.075,167,967 - 5,168,902 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl75,167,967 - 5,168,902 (-)Ensemblrn6Rnor6.0
Rnor_5.075,158,514 - 5,159,449 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.473,294,433 - 3,295,368 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera711,064,862 - 11,065,797 (+)NCBICelera
RGSC_v3.173,294,432 - 3,295,368 (-)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
atrazine  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline

Genomics

Variants

.
Variants in Or6c3d
1 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat


Expression

RNA-SEQ Expression

ectoderm
mesenchyme
nervous system
renal system
1 1 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000090661   ⟹   ENSRNOP00000070676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl72,754,897 - 2,755,832 (+)Ensembl
mRatBN7.2 Ensembl72,126,405 - 2,127,340 (+)Ensembl
Rnor_6.0 Ensembl75,167,967 - 5,168,902 (-)Ensembl
RefSeq Acc Id: NM_001000940   ⟹   NP_001000940
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr872,754,897 - 2,755,832 (+)NCBI
mRatBN7.272,126,405 - 2,127,340 (+)NCBI
Rnor_6.075,167,967 - 5,168,902 (-)NCBI
Rnor_5.075,158,514 - 5,159,449 (-)NCBI
RGSC_v3.473,294,433 - 3,295,368 (-)RGD
Celera711,064,862 - 11,065,797 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000940 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070676
  ENSRNOP00000070676.1
RefSeq Acc Id: NP_001000940   ⟸   NM_001000940
- UniProtKB: A0A0G2JYJ3 (UniProtKB/TrEMBL),   A0A8I6G2N5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070676   ⟸   ENSRNOT00000090661
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JYJ3-F1-model_v2 AlphaFold A0A0G2JYJ3 1-311 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1332890 AgrOrtholog
BioCyc Gene G2FUF-35292 BioCyc
Ensembl Genes ENSRNOG00000061448 Ensembl
  ENSRNOG00000065664 Ensembl
  ENSRNOG00000065705 Ensembl
  ENSRNOG00000085412 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000090661 ENTREZGENE
  ENSRNOT00000090661.3 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
  Olfact_rcpt_6C-like UniProtKB/TrEMBL
KEGG Report rno:405277 UniProtKB/TrEMBL
NCBI Gene 405277 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 6C3 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or6c3d PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000061448 RatGTEx
  ENSRNOG00000065664 RatGTEx
  ENSRNOG00000065705 RatGTEx
  ENSRNOG00000085412 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0G2JYJ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G2N5 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or6c3d  olfactory receptor family 6 subfamily C member 3D  Olr894  olfactory receptor 894  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr894  olfactory receptor 894   Olr894_predicted  olfactory receptor 894 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr894_predicted  olfactory receptor 894 (predicted)      Symbol and Name status set to approved 70820 APPROVED