Or8g51 (olfactory receptor family 8 subfamily G member 51) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Or8g51 (olfactory receptor family 8 subfamily G member 51) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or8g51 (Ensembl: LOC100909423)
Name: olfactory receptor family 8 subfamily G member 51 (Ensembl:olfactory receptor 150-like)
RGD ID: 1332639
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of smell.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC100909423; olfactory receptor 1257; olfactory receptor 150-like; olfactory receptor gene Olr1257; olfactory receptor Olr1257; Olr1257; ratchr8-40846636-40845701_ORF
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8847,699,417 - 47,700,352 (-)NCBIGRCr8
mRatBN7.2838,802,241 - 38,803,176 (-)NCBImRatBN7.2mRatBN7.2
UTH_Rnor_SHR_Utx844,285,146 - 44,286,081 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0842,569,220 - 42,570,155 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0840,431,277 - 40,432,212 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0842,429,993 - 42,430,928 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0842,417,375 - 42,420,834 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4840,836,935 - 40,837,870NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1840,845,700 - 40,846,636NCBI
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or8g51Ratdetection of chemical stimulus involved in sensory perception of smell  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 
Or8g51RatG protein-coupled receptor signaling pathway  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or8g51Ratolfactory receptor activity  IEA (All species)1303377CREATED_DATE field changed to comply with GOC standards. Original CREATED_DATE: 2005-02-17RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Or8g51Rattaste/olfaction phenotype  IEA 1303377 RGD 

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


.

.
Variants in Or8g51
10 total Variants

Predicted Target Of
Summary Value
Count of predictions:155
Count of miRNA genes:56
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000071070, ENSRNOT00000071677, ENSRNOT00000072172
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 54 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83084815442692818Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)830848154101699754Rat
1300146Rf17Renal function QTL 172.9renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)82824291273242912Rat

1 to 10 of 54 rows



reproductive system
2


RefSeq Transcripts NM_001000596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC112348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000071070   ⟹   ENSRNOP00000067670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3158,984,879 - 158,985,814 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000072172   ⟹   ENSRNOP00000067692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl842,429,993 - 42,430,928 (-)Ensembl
RefSeq Acc Id: NM_001000596   ⟹   NP_001000596
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8847,699,417 - 47,700,352 (-)NCBI
mRatBN7.2838,802,241 - 38,803,176 (-)NCBI
Rnor_6.0842,429,993 - 42,430,928 (-)NCBI
Rnor_5.0842,417,375 - 42,420,834 (-)NCBI
RGSC_v3.4840,836,935 - 40,837,870 (-)RGD
Sequence:
Protein RefSeqs NP_001000596 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000076731
RefSeq Acc Id: NP_001000596   ⟸   NM_001000596
- UniProtKB: A6KUF5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067692   ⟸   ENSRNOT00000072172
Ensembl Acc Id: ENSRNOP00000067670   ⟸   ENSRNOT00000071070
G-protein coupled receptors family 1 profile

Name Modeler Protein Id AA Range Protein Structure
AF-M0RDG9-F1-model_v2 AlphaFold M0RDG9 1-311 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 22 of 22 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-30940 BioCyc
Ensembl Genes ENSRNOG00000045625 Ensembl
  ENSRNOG00000046510 Ensembl
  ENSRNOG00000074737 ENTREZGENE
Ensembl Transcript ENSRNOT00000094640 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
NCBI Gene 367061 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or8g51 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000045625 RatGTEx
  ENSRNOG00000046510 RatGTEx
  ENSRNOG00000074737 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6KUF5 ENTREZGENE, UniProtKB/TrEMBL
1 to 22 of 22 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or8g51  olfactory receptor family 8 subfamily G member 51  Olr1257  olfactory receptor 1257  Symbol and Name Changed 1299863 APPROVED
2021-03-09 Olr1257  olfactory receptor 1257  LOC100909423  olfactory receptor 150-like  Data merged from RGD:6503544 737654 PROVISIONAL
2012-07-05 LOC100909423  olfactory receptor 150-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Olr1257  olfactory receptor 1257   Olr1257_predicted  olfactory receptor 1257 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1257_predicted  olfactory receptor 1257 (predicted)      Symbol and Name status set to approved 70820 APPROVED