Sowahb (sosondowah ankyrin repeat domain family member B) - Rat Genome Database

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Gene: Sowahb (sosondowah ankyrin repeat domain family member B) Rattus norvegicus
Analyze
Symbol: Sowahb
Name: sosondowah ankyrin repeat domain family member B
RGD ID: 1311994
Description: Orthologous to human SOWAHB (sosondowah ankyrin repeat domain family member B); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ankrd56; ankyrin repeat domain 56; ankyrin repeat domain-containing protein SOWAHB; hypothetical LOC289501; LOC289501; RGD1311994
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81415,313,561 - 15,317,396 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1415,309,246 - 15,321,591 (+)EnsemblGRCr8
mRatBN7.21415,029,203 - 15,033,038 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1415,029,395 - 15,031,698 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1415,038,041 - 15,041,876 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01416,357,056 - 16,360,891 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01415,052,292 - 15,056,127 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01416,491,023 - 16,495,764 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1416,491,573 - 16,493,876 (+)Ensemblrn6Rnor6.0
Rnor_5.01416,417,015 - 16,421,756 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41416,587,783 - 16,590,086 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1414,431,239 - 14,435,980 (+)NCBICelera
RGSC_v3.11416,587,782 - 16,590,086 (+)NCBI
Cytogenetic Map14p22NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Sowahb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81415,313,561 - 15,317,396 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1415,309,246 - 15,321,591 (+)EnsemblGRCr8
mRatBN7.21415,029,203 - 15,033,038 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1415,029,395 - 15,031,698 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1415,038,041 - 15,041,876 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01416,357,056 - 16,360,891 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01415,052,292 - 15,056,127 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01416,491,023 - 16,495,764 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1416,491,573 - 16,493,876 (+)Ensemblrn6Rnor6.0
Rnor_5.01416,417,015 - 16,421,756 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41416,587,783 - 16,590,086 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1414,431,239 - 14,435,980 (+)NCBICelera
RGSC_v3.11416,587,782 - 16,590,086 (+)NCBI
Cytogenetic Map14p22NCBI
SOWAHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38476,894,152 - 76,898,144 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl476,894,152 - 76,898,144 (-)Ensemblhg38GRCh38
GRCh37477,815,305 - 77,819,297 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36478,035,106 - 78,038,026 (-)NCBIBuild 36Build 36hg18NCBI36
Celera475,117,434 - 75,120,354 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef473,568,396 - 73,571,316 (-)NCBIHuRef
CHM1_1477,792,588 - 77,795,508 (-)NCBICHM1_1
T2T-CHM13v2.0480,234,914 - 80,238,906 (-)NCBIT2T-CHM13v2.0
Sowahb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39593,188,981 - 93,192,910 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl593,188,982 - 93,192,881 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38593,041,123 - 93,045,022 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl593,041,123 - 93,045,022 (-)Ensemblmm10GRCm38
MGSCv37593,470,149 - 93,474,048 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36594,116,375 - 94,120,155 (-)NCBIMGSCv36mm8
Celera591,194,083 - 91,197,982 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map547.29NCBI
Sowahb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554331,539,001 - 1,541,370 (-)Ensembl
ChiLan1.0NW_0049554331,537,658 - 1,541,574 (-)NCBIChiLan1.0ChiLan1.0
SOWAHB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2353,169,135 - 53,180,147 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1453,357,354 - 53,374,524 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0447,256,096 - 47,317,472 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1453,142,782 - 53,156,323 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl453,144,284 - 53,146,343 (+)EnsemblpanPan2panpan1.1
SOWAHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1321,473,709 - 1,476,660 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl321,474,316 - 1,476,535 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3240,409,534 - 40,412,391 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0321,497,526 - 1,500,406 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl321,498,144 - 1,500,379 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1321,495,048 - 1,497,905 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0321,450,923 - 1,453,790 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03238,721,951 - 38,724,808 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sowahb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528510,699,976 - 10,703,776 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936676804,782 - 807,112 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936676804,411 - 807,653 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOWAHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl872,539,307 - 72,543,298 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1872,538,804 - 72,543,316 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2876,737,802 - 76,742,371 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SOWAHB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1725,389,247 - 25,400,161 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl725,397,385 - 25,399,766 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660373,742,522 - 3,753,488 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sowahb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475714,104,865 - 14,107,099 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475714,104,605 - 14,108,490 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Sowahb
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1115,853,789 - 5,856,476 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sowahb
39 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:24
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000002995
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14395787821572472Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14395787818558812Rat
7411573Bw139Body weight QTL 1394.70.001body mass (VT:0001259)body weight gain (CMO:0000420)14140068101Rat
9589814Gluco67Glucose level QTL 674.540.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14140068101Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14939329839411170Rat
631212Bw5Body weight QTL55.43retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)141133490630674469Rat
2302277Gluco38Glucose level QTL 385.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)141133471628389666Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14395787831121464Rat
71117Niddm17Non-insulin dependent diabetes mellitus QTL 172.35blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14117877928Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14395787824886169Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141415516Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14131893212Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
1300140Srn3Serum renin concentration QTL 33.19blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)141513759431238250Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 9 59 131 89 90 59 18 59 6 267 105 10 113 81 91 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002995   ⟹   ENSRNOP00000002995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1415,313,432 - 15,317,057 (+)Ensembl
mRatBN7.2 Ensembl1415,029,395 - 15,031,698 (+)Ensembl
Rnor_6.0 Ensembl1416,491,573 - 16,493,876 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000132877   ⟹   ENSRNOP00000100499
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1415,309,246 - 15,321,591 (+)Ensembl
RefSeq Acc Id: NM_001398870   ⟹   NP_001385799
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81415,313,561 - 15,317,396 (+)NCBI
mRatBN7.21415,029,203 - 15,033,038 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001385799 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002995.7
  ENSRNOP00000100499
  ENSRNOP00000100499.1
Ensembl Acc Id: ENSRNOP00000002995   ⟸   ENSRNOT00000002995
RefSeq Acc Id: NP_001385799   ⟸   NM_001398870
- UniProtKB: D4A4Q1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100499   ⟸   ENSRNOT00000132877

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A4Q1-F1-model_v2 AlphaFold D4A4Q1 1-767 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311994 AgrOrtholog
BioCyc Gene G2FUF-16279 BioCyc
Ensembl Genes ENSRNOG00000002202 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002995.8 UniProtKB/TrEMBL
  ENSRNOT00000132877 ENTREZGENE
  ENSRNOT00000132877.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
NCBI Gene 289501 ENTREZGENE
PANTHER ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHB UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
PhenoGen Sowahb PhenoGen
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002202 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt A0ABK0LBQ6_RAT UniProtKB/TrEMBL
  D4A4Q1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-13 Sowahb  sosondowah ankyrin repeat domain family member B  Ankrd56  ankyrin repeat domain 56  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Ankrd56  ankyrin repeat domain 56  RGD1311994_predicted  hypothetical LOC289501 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1311994_predicted  hypothetical LOC289501 (predicted)  LOC289501_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC289501_predicted  hypothetical LOC289501 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL