Siglec1 (sialic acid binding Ig like lectin 1) - Rat Genome Database

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Gene: Siglec1 (sialic acid binding Ig like lectin 1) Rattus norvegicus
Analyze
Symbol: Siglec1
Name: sialic acid binding Ig like lectin 1
RGD ID: 1311953
Description: Predicted to enable virion binding activity. Predicted to be involved in clathrin-dependent endocytosis of virus by host cell; negative regulation of phagocytosis; and negative regulation of type I interferon production. Predicted to act upstream of or within positive regulation of T cell apoptotic process and positive regulation of extrinsic apoptotic signaling pathway. Predicted to be located in endocytic vesicle. Predicted to be active in early endosome; late endosome; and plasma membrane. Orthologous to human SIGLEC1 (sialic acid binding Ig like lectin 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: sialic acid binding Ig-like lectin 1, sialoadhesin; sialoadhesin; Sn
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,740,171 - 138,759,966 (-)NCBIGRCr8
mRatBN7.23118,287,988 - 118,307,125 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,287,988 - 118,306,850 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,182,321 - 122,201,175 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,781,499 - 130,800,293 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,438,431 - 128,457,285 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,612,067 - 123,631,718 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,612,067 - 123,631,109 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,111,340 - 130,130,084 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,769,404 - 118,787,908 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,676,987 - 118,692,769 (-)NCBI
Celera3117,098,468 - 117,117,016 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11971865   PMID:12857889   PMID:20084110   PMID:21359217   PMID:22526486   PMID:22630829   PMID:23408841  


Genomics

Comparative Map Data
Siglec1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83138,740,171 - 138,759,966 (-)NCBIGRCr8
mRatBN7.23118,287,988 - 118,307,125 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3118,287,988 - 118,306,850 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3122,182,321 - 122,201,175 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03130,781,499 - 130,800,293 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03128,438,431 - 128,457,285 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03123,612,067 - 123,631,718 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,612,067 - 123,631,109 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,111,340 - 130,130,084 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,769,404 - 118,787,908 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13118,676,987 - 118,692,769 (-)NCBI
Celera3117,098,468 - 117,117,016 (-)NCBICelera
Cytogenetic Map3q36NCBI
SIGLEC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,686,970 - 3,712,600 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl203,686,970 - 3,712,600 (-)EnsemblGRCh38hg38GRCh38
GRCh37203,667,617 - 3,693,247 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,615,617 - 3,635,775 (-)NCBINCBI36Build 36hg18NCBI36
Build 34203,617,206 - 3,635,775NCBI
Celera203,729,495 - 3,749,653 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef203,615,947 - 3,636,103 (-)NCBIHuRef
CHM1_1203,667,931 - 3,688,082 (-)NCBICHM1_1
T2T-CHM13v2.0203,717,911 - 3,743,544 (-)NCBIT2T-CHM13v2.0
Siglec1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,911,140 - 130,928,697 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2130,911,140 - 130,928,685 (-)EnsemblGRCm39 Ensembl
GRCm382131,067,801 - 131,086,778 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,069,220 - 131,086,765 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,894,956 - 130,912,501 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362130,760,184 - 130,778,206 (-)NCBIMGSCv36mm8
Celera2132,293,968 - 132,311,385 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.26NCBI
Siglec1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,536,266 - 14,560,632 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,539,284 - 14,560,614 (-)NCBIChiLan1.0ChiLan1.0
SIGLEC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,650,680 - 4,679,583 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1204,647,500 - 4,676,408 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0203,769,118 - 3,795,678 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1203,526,791 - 3,551,070 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,526,791 - 3,552,309 (-)Ensemblpanpan1.1panPan2
SIGLEC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,636,143 - 17,667,791 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,636,026 - 17,666,854 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,465,992 - 17,496,959 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02418,055,099 - 18,086,072 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2418,055,165 - 18,080,168 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12417,649,935 - 17,680,868 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02417,761,270 - 17,792,416 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02418,088,684 - 18,119,668 (+)NCBIUU_Cfam_GSD_1.0
Siglec1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640166,542,946 - 166,568,774 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648514,979,819 - 14,998,004 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648514,979,838 - 14,999,047 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIGLEC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1731,994,632 - 32,021,239 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11731,994,505 - 32,021,239 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,328,314 - 36,347,405 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SIGLEC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1234,371,605 - 34,417,105 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl234,371,519 - 34,392,034 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607110,057,143 - 10,078,848 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Siglec1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,783,327 - 4,798,378 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247414,781,347 - 4,802,893 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Siglec1
175 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:170
Count of miRNA genes:117
Interacting mature miRNAs:136
Transcripts:ENSRNOT00000028855
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
12879848Bw181Body weght QTL 1810.015body mass (VT:0001259)body weight (CMO:0000012)370348525121056321Rat
2301414Kidm37Kidney mass QTL 370.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)370653097121056321Rat
1600376Arunc5Aerobic running capacity QTL 50.21exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)373376539118376539Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat

Markers in Region
Sn  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,297,352 - 118,297,875 (+)MAPPERmRatBN7.2
Rnor_6.03123,621,432 - 123,621,954NCBIRnor6.0
Rnor_5.03130,120,705 - 130,121,227UniSTSRnor5.0
RGSC_v3.43118,778,769 - 118,779,291UniSTSRGSC3.4
Celera3117,107,833 - 117,108,345UniSTS
Cytogenetic Map3q36UniSTS
RH135254  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23118,289,009 - 118,289,210 (+)MAPPERmRatBN7.2
Rnor_6.03123,613,089 - 123,613,289NCBIRnor6.0
Rnor_5.03130,112,362 - 130,112,562UniSTSRnor5.0
RGSC_v3.43118,770,426 - 118,770,626UniSTSRGSC3.4
Celera3117,099,490 - 117,099,690UniSTS
RH 3.4 Map31014.7UniSTS
Cytogenetic Map3q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 11 3
Low 1 22 51 35 8 35 8 10 8 15 19 11 8
Below cutoff 2 21 4 4 4 1 56 20 18

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000028855   ⟹   ENSRNOP00000028855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,287,988 - 118,306,850 (-)Ensembl
Rnor_6.0 Ensembl3123,612,067 - 123,630,929 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000091493   ⟹   ENSRNOP00000072470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3118,287,988 - 118,306,850 (-)Ensembl
Rnor_6.0 Ensembl3123,612,257 - 123,631,109 (-)Ensembl
RefSeq Acc Id: NM_001107777   ⟹   NP_001101247
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,741,019 - 138,759,881 (-)NCBI
mRatBN7.23118,287,988 - 118,306,850 (-)NCBI
Rnor_6.03123,612,067 - 123,630,929 (-)NCBI
Rnor_5.03130,111,340 - 130,130,084 (-)NCBI
RGSC_v3.43118,769,404 - 118,787,908 (-)RGD
Celera3117,098,468 - 117,117,016 (-)RGD
Sequence:
RefSeq Acc Id: XM_006235024   ⟹   XP_006235086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,740,171 - 138,759,965 (-)NCBI
mRatBN7.23118,288,481 - 118,307,125 (-)NCBI
Rnor_6.03123,612,824 - 123,631,718 (-)NCBI
Rnor_5.03130,111,340 - 130,130,084 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591746   ⟹   XP_017447235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,740,171 - 138,759,965 (-)NCBI
mRatBN7.23118,288,481 - 118,307,125 (-)NCBI
Rnor_6.03123,612,824 - 123,631,718 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591747   ⟹   XP_017447236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,740,171 - 138,759,966 (-)NCBI
mRatBN7.23118,288,481 - 118,307,125 (-)NCBI
Rnor_6.03123,612,824 - 123,631,718 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591748   ⟹   XP_017447237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,740,171 - 138,759,965 (-)NCBI
mRatBN7.23118,288,481 - 118,307,124 (-)NCBI
Rnor_6.03123,612,824 - 123,631,718 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591749   ⟹   XP_017447238
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83138,740,171 - 138,759,965 (-)NCBI
mRatBN7.23118,288,481 - 118,307,125 (-)NCBI
Rnor_6.03123,612,824 - 123,631,718 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001101247   ⟸   NM_001107777
- Peptide Label: precursor
- UniProtKB: D3ZVM6 (UniProtKB/TrEMBL),   A6HQC1 (UniProtKB/TrEMBL),   A0A0G2K320 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235086   ⟸   XM_006235024
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K320 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447237   ⟸   XM_017591748
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K320 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447235   ⟸   XM_017591746
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K320 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447238   ⟸   XM_017591749
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K320 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447236   ⟸   XM_017591747
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K320 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028855   ⟸   ENSRNOT00000028855
RefSeq Acc Id: ENSRNOP00000072470   ⟸   ENSRNOT00000091493
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K320-F1-model_v2 AlphaFold A0A0G2K320 1-1693 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692443
Promoter ID:EPDNEW_R2968
Type:single initiation site
Name:Siglec1_1
Description:sialic acid binding Ig like lectin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03123,630,399 - 123,630,459EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311953 AgrOrtholog
BioCyc Gene G2FUF-47830 BioCyc
Ensembl Genes ENSRNOG00000021243 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028855 ENTREZGENE
  ENSRNOT00000028855.8 UniProtKB/TrEMBL
  ENSRNOT00000091493.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
KEGG Report rno:311426 UniProtKB/TrEMBL
NCBI Gene 311426 ENTREZGENE
PANTHER SIALOADHESIN UniProtKB/TrEMBL
  SIALOADHESIN UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Ig_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  PF00047 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Siglec1 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021243 RatGTEx
SMART IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0G2K320 ENTREZGENE, UniProtKB/TrEMBL
  A6HQC1 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVM6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-27 Siglec1  sialic acid binding Ig like lectin 1  Siglec1  sialic acid binding Ig-like lectin 1, sialoadhesin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Siglec1  sialic acid binding Ig-like lectin 1, sialoadhesin   Siglec1_predicted  sialic acid binding Ig-like lectin 1, sialoadhesin (predicted)  'predicted' is removed 2292626 APPROVED
2008-01-09 Siglec1_predicted  sialic acid binding Ig-like lectin 1, sialoadhesin (predicted)  LOC688116  similar to sialoadhesin  Data merged from RGD:1592443 1643240 APPROVED
2006-11-20 LOC688116  similar to sialoadhesin      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Siglec1_predicted  sialic acid binding Ig-like lectin 1, sialoadhesin (predicted)  Sn_predicted  sialoadhesin (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-12 Sn_predicted  sialoadhesin (predicted)      Symbol and Name status set to approved 70820 APPROVED