SIGLEC1 (sialic acid binding Ig-like lectin 1, sialoadhesin)

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Keyword

Gene: SIGLEC1 (sialic acid binding Ig-like lectin 1, sialoadhesin) Homo sapiens

Symbol:

SIGLEC1

Name:

sialic acid binding Ig-like lectin 1, sialoadhesin

Description:

This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

CD169; dJ1009E24.1; DKFZp667F058; FLJ00051; FLJ00055; FLJ00073; FLJ00411; FLJ32150; OTTHUMP00000030124; sialic acid-binding Ig-like lectin 1; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC-1; SN

Orthologs:

Mus musculus : Siglec1 (sialic acid binding Ig-like lectin 1, sialoadhesin) MGI
Rattus norvegicus : Siglec1 (sialic acid binding Ig-like lectin 1, sialoadhesin)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	20	3,611,462 - 3,631,633	-	NCBI
Human Genome Assembly HuRef	20	3,615,947 - 3,636,103	-	NCBI
Human Genome Assembly GRCh37	20	3,667,617 - 3,687,775	-	NCBI
Human Genome Assembly Build 36	20	3,615,617 - 3,635,775	-	NCBI
Human Cytogenetic Map	20	p13		NCBI
Human Genome Assembly	20	3,617,206 - 3,635,775		NCBI