Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | affects expression | ISO | Osr1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of OSR1 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | Osr1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of OSR1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of OSR1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of OSR1 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Osr1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of OSR1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of OSR1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Osr1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of OSR1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of OSR1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Osr1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of OSR1 mRNA | CTD | PMID:19933214 | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of OSR1 mRNA | CTD | PMID:28522335 | 4,4'-sulfonyldiphenol | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of OSR1 mRNA | CTD | PMID:30951980 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of OSR1 mRNA | CTD | PMID:24780913 | acetylsalicylic acid | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Aspirin results in increased expression of OSR1 mRNA | CTD | PMID:15928584 | aflatoxin B1 | affects expression | ISO | OSR1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of OSR1 protein | CTD | PMID:20106945 | aflatoxin B1 | decreases methylation | ISO | OSR1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of OSR1 gene and Aflatoxin B1 results in decreased methylation of OSR1 promoter | CTD | PMID:27153756 and PMID:30157460 | aflatoxin B1 | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of OSR1 mRNA | CTD | PMID:22100608 | Aflatoxin B2 alpha | increases methylation | ISO | OSR1 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of OSR1 promoter | CTD | PMID:30157460 | antirheumatic drug | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of OSR1 mRNA | CTD | PMID:24449571 | Aroclor 1254 | decreases expression | ISO | Osr1 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of OSR1 mRNA | CTD | PMID:23650126 | arsane | increases methylation | ISO | OSR1 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of OSR1 promoter | CTD | PMID:21291286 | arsenic atom | increases methylation | ISO | OSR1 (Homo sapiens) | 6480464 | Arsenic results in increased methylation of OSR1 promoter | CTD | PMID:21291286 | benzo[a]pyrene | decreases expression | ISO | Osr1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of OSR1 mRNA | CTD | PMID:15034205 | benzo[a]pyrene | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of OSR1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | OSR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of OSR1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | OSR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of OSR1 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | OSR1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of OSR1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | Osr1 (Mus musculus) | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of OSR1 mRNA] | CTD | PMID:15034205 | benzo[a]pyrene diol epoxide I | affects expression | ISO | OSR1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | benzo[e]pyrene | increases methylation | ISO | OSR1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of OSR1 promoter | CTD | PMID:30157460 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of OSR1 mRNA | CTD | PMID:25181051 more ... | bisphenol A | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of OSR1 mRNA | CTD | PMID:30951980 more ... | bisphenol F | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of OSR1 mRNA | CTD | PMID:30951980 | bleomycin A2 | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | Bleomycin results in increased expression of OSR1 protein | CTD | PMID:34460027 | buta-1,3-diene | decreases expression | ISO | Osr1 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of OSR1 mRNA | CTD | PMID:29038090 | butan-1-ol | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of OSR1 mRNA | CTD | PMID:29432896 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of OSR1 mRNA | CTD | PMID:19167457 | carbon nanotube | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to OSR1 gene] | CTD | PMID:28238834 | cisplatin | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of OSR1 mRNA | CTD | PMID:27392435 | cytarabine | decreases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of OSR1 mRNA | CTD | PMID:21198554 | decabromodiphenyl ether | decreases expression | EXP | | 6480464 | decabromobiphenyl ether results in decreased expression of OSR1 mRNA | CTD | PMID:23640034 | dibutyl phthalate | decreases expression | ISO | Osr1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of OSR1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of OSR1 mRNA | CTD | PMID:24893172 | dorsomorphin | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OSR1 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of OSR1 mRNA | CTD | PMID:29803840 | eplerenone | multiple interactions | ISO | Osr1 (Mus musculus) | 6480464 | eplerenone inhibits the reaction [AGT protein results in increased phosphorylation of OSR1 protein] | CTD | PMID:20175999 | ethanol | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of OSR1 mRNA | CTD | PMID:29432896 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of OSR1 mRNA | CTD | PMID:27387713 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of OSR1 mRNA | CTD | PMID:33387578 | iron dichloride | decreases expression | ISO | OSR1 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of OSR1 mRNA | CTD | PMID:35984750 | mercury dichloride | increases expression | EXP | | 6480464 | Mercuric Chloride results in increased expression of OSR1 mRNA | CTD | PMID:16507785 | methapyrilene | increases methylation | ISO | OSR1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of OSR1 promoter | CTD | PMID:30157460 | methotrexate | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of OSR1 mRNA | CTD | PMID:24449571 | nickel atom | decreases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of OSR1 mRNA | CTD | PMID:25583101 | paracetamol | affects expression | ISO | Osr1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of OSR1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of OSR1 mRNA | CTD | PMID:33387578 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of OSR1 mRNA | CTD | PMID:32680482 | perfluorohexanesulfonic acid | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of OSR1 mRNA | CTD | PMID:37995155 | phenylmercury acetate | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of OSR1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OSR1 mRNA | CTD | PMID:27188386 | progesterone | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | Progesterone results in increased expression of OSR1 mRNA | CTD | PMID:22238285 | resveratrol | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of OSR1 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | OSR1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of OSR1 mRNA | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of OSR1 mRNA | CTD | PMID:25895662 | silver atom | decreases expression | ISO | Osr1 (Mus musculus) | 6480464 | Silver results in decreased expression of OSR1 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Osr1 (Mus musculus) | 6480464 | Silver results in decreased expression of OSR1 mRNA | CTD | PMID:27131904 | sodium arsenite | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of OSR1 mRNA | CTD | PMID:22714537 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of OSR1 mRNA | CTD | PMID:23137061 | sunitinib | decreases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of OSR1 mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | Osr1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of OSR1 mRNA | CTD | PMID:17555576 | temozolomide | decreases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of OSR1 mRNA | CTD | PMID:31758290 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of OSR1 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of OSR1 mRNA | CTD | PMID:23409001 | titanium dioxide | decreases expression | ISO | Osr1 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of OSR1 mRNA | CTD | PMID:23557971 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of OSR1 mRNA | CTD | PMID:33387578 | triclosan | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Triclosan results in increased expression of OSR1 mRNA | CTD | PMID:30510588 | urethane | increases expression | ISO | OSR1 (Homo sapiens) | 6480464 | Urethane results in increased expression of OSR1 mRNA | CTD | PMID:28818685 | valproic acid | increases expression | ISO | Osr1 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of OSR1 mRNA | CTD | PMID:24896083 | valsartan | multiple interactions | ISO | Osr1 (Mus musculus) | 6480464 | Valsartan inhibits the reaction [AGT protein results in increased phosphorylation of OSR1 protein] | CTD | PMID:20175999 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of OSR1 mRNA | CTD | PMID:23869203 | |