Osr1 (odd-skipped related transcription factor 1) - Rat Genome Database

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Gene: Osr1 (odd-skipped related transcription factor 1) Rattus norvegicus
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Symbol: Osr1
Name: odd-skipped related transcription factor 1
RGD ID: 1311807
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including embryonic limb morphogenesis; kidney development; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within gonad development; intermediate mesoderm development; and metanephros development. Located in cell cortex and cytosol. Orthologous to human OSR1 (odd-skipped related transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC298878; odd-skipped related 1; odd-skipped related 1 (Drosophila); odd-skipped related transciption factor 1; Odd1; protein odd-skipped-related 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8638,088,688 - 38,100,010 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl638,093,011 - 38,100,021 (+)EnsemblGRCr8
mRatBN7.2632,369,561 - 32,380,822 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl632,373,816 - 32,380,817 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx632,670,489 - 32,672,848 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0632,986,375 - 32,988,736 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0632,460,987 - 32,463,354 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd639,540,575 - 39,542,934 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive638,976,881 - 38,979,240 (+)NCBILyon_Normotensive
Lyon_Hypertensive636,772,699 - 36,775,058 (+)NCBILyon_Hypertensive
F344_StmMcwi635,989,654 - 35,992,025 (+)NCBIF344_StmMcwi
Rnor_6.0635,314,431 - 35,321,458 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl635,314,444 - 35,321,667 (+)Ensemblrn6Rnor6.0
Rnor_5.0645,074,989 - 45,086,319 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4633,074,410 - 33,076,769 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera631,814,629 - 31,816,988 (+)NCBICelera
RGSC_v3.1633,062,739 - 33,079,153 (+)NCBI
Cytogenetic Map6q14NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetylsalicylic acid  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
buta-1,3-diene  (ISO)
butan-1-ol  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cytarabine  (ISO)
decabromodiphenyl ether  (EXP)
dibutyl phthalate  (EXP,ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
eplerenone  (ISO)
ethanol  (ISO)
furan  (EXP)
gentamycin  (EXP)
iron dichloride  (ISO)
mercury dichloride  (EXP)
methapyrilene  (ISO)
methotrexate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nickel atom  (ISO)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
urethane  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell differentiation  (IEA,ISO)
cell proliferation involved in kidney development  (IEA,ISO,ISS)
cellular response to retinoic acid  (IEA,ISO)
chondrocyte differentiation  (IEA,ISO)
DNA-templated transcription  (IEA)
embryonic digit morphogenesis  (IEA,ISO)
embryonic forelimb morphogenesis  (IEA,ISO)
embryonic hindlimb morphogenesis  (IEA,ISO)
embryonic skeletal joint development  (IEA,ISO)
embryonic skeletal joint morphogenesis  (IEA,ISO)
embryonic skeletal limb joint morphogenesis  (IEA,ISO)
gonad development  (ISO)
heart development  (ISO,ISS)
intermediate mesoderm development  (ISO)
mesangial cell development  (IEA,ISO,ISS)
mesonephric duct morphogenesis  (IEA,ISO,ISS)
mesonephros development  (IEA,ISO,ISS)
metanephric cap mesenchymal cell proliferation involved in metanephros development  (IEA,ISO,ISS)
metanephric epithelium development  (IEA,ISO,ISS)
metanephric glomerulus vasculature development  (IEA,ISO,ISS)
metanephric interstitial fibroblast development  (IEA,ISO,ISS)
metanephric mesenchymal cell differentiation  (IEA,ISO,ISS)
metanephric mesenchyme development  (IEA,ISO,ISS)
metanephric mesenchyme morphogenesis  (IEA,ISO,ISS)
metanephric nephron tubule development  (IEA,ISO,ISS)
metanephric smooth muscle tissue development  (IEA,ISO,ISS)
metanephros development  (ISO)
middle ear morphogenesis  (IEA,ISO,ISS)
negative regulation of apoptotic process  (IEA,ISO,ISS)
negative regulation of epithelial cell differentiation  (IEA,ISO,ISS)
negative regulation of nephron tubule epithelial cell differentiation  (IEA,ISO,ISS)
negative regulation of sodium ion transmembrane transport  (IEA,ISO)
negative regulation of transcription by RNA polymerase II  (IBA,IEA,ISO)
negative regulation of transmembrane transport  (IEA,ISO)
odontogenesis  (IEA,ISO,ISS)
pattern specification involved in metanephros development  (IEA,ISO,ISS)
pattern specification process  (IBA)
positive regulation of bone mineralization  (IEA,ISO)
positive regulation of epithelial cell proliferation  (IEA,ISO,ISS)
positive regulation of gastrulation  (IEA,ISO,ISS)
positive regulation of gene expression  (IEA,ISO,ISS)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
posterior mesonephric tubule development  (IEA,ISO,ISS)
pronephros development  (IBA,IEA,ISO,ISS)
renal vesicle progenitor cell differentiation  (IEA,ISO,ISS)
roof of mouth development  (IEA,ISO,ISS)
sodium ion transmembrane transport  (IEA,ISO)
specification of anterior mesonephric tubule identity  (IEA,ISO,ISS)
specification of posterior mesonephric tubule identity  (IEA,ISO,ISS)
stem cell differentiation  (IEA,ISO,ISS)
ureter urothelium development  (IEA,ISO,ISS)
ureteric bud development  (IEA,ISO,ISS)
urogenital system development  (IBA,IEA,ISO,ISS)

Cellular Component
cell cortex  (IDA)
cytosol  (IDA)
nucleus  (IBA,IEA,ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Identification of the WNK-SPAK/OSR1 signaling pathway in rodent and human lenses. Vorontsova I, etal., Invest Ophthalmol Vis Sci. 2014 Dec 16;56(1):310-21. doi: 10.1167/iovs.14-15911.
Additional References at PubMed
PMID:12477932   PMID:16223478   PMID:16669787   PMID:16790474   PMID:17547533   PMID:18835385   PMID:19307180   PMID:19389375   PMID:20171952   PMID:21262216   PMID:21281489   PMID:22238094  
PMID:25531585  


Genomics

Comparative Map Data
Osr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8638,088,688 - 38,100,010 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl638,093,011 - 38,100,021 (+)EnsemblGRCr8
mRatBN7.2632,369,561 - 32,380,822 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl632,373,816 - 32,380,817 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx632,670,489 - 32,672,848 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0632,986,375 - 32,988,736 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0632,460,987 - 32,463,354 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd639,540,575 - 39,542,934 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive638,976,881 - 38,979,240 (+)NCBILyon_Normotensive
Lyon_Hypertensive636,772,699 - 36,775,058 (+)NCBILyon_Hypertensive
F344_StmMcwi635,989,654 - 35,992,025 (+)NCBIF344_StmMcwi
Rnor_6.0635,314,431 - 35,321,458 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl635,314,444 - 35,321,667 (+)Ensemblrn6Rnor6.0
Rnor_5.0645,074,989 - 45,086,319 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4633,074,410 - 33,076,769 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera631,814,629 - 31,816,988 (+)NCBICelera
RGSC_v3.1633,062,739 - 33,079,153 (+)NCBI
Cytogenetic Map6q14NCBI
OSR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38219,344,874 - 19,358,623 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl219,351,485 - 19,359,486 (-)Ensemblhg38GRCh38
GRCh37219,551,246 - 19,558,384 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36219,414,727 - 19,421,853 (-)NCBIBuild 36Build 36hg18NCBI36
Celera219,413,711 - 19,420,835 (-)NCBICelera
Cytogenetic Map2p24.1NCBI
HuRef219,308,802 - 19,315,925 (-)NCBIHuRef
CHM1_1219,480,638 - 19,487,763 (-)NCBICHM1_1
T2T-CHM13v2.0219,384,294 - 19,391,428 (-)NCBIT2T-CHM13v2.0
Osr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39129,624,442 - 9,631,500 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl129,620,116 - 9,631,500 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38129,574,442 - 9,581,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl129,570,116 - 9,581,500 (+)Ensemblmm10GRCm38
MGSCv37129,581,248 - 9,588,306 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36129,600,505 - 9,606,919 (+)NCBIMGSCv36mm8
Celera129,956,176 - 9,963,227 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map124.05NCBI
Osr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554691,953,370 - 1,961,390 (-)Ensembl
ChiLan1.0NW_0049554691,954,470 - 1,961,344 (-)NCBIChiLan1.0ChiLan1.0
OSR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212107,175,816 - 107,183,009 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A107,179,842 - 107,186,981 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A19,333,101 - 19,340,267 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A19,451,067 - 19,458,229 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A19,451,067 - 19,458,229 (-)EnsemblpanPan2panpan1.1
OSR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11714,508,543 - 14,515,657 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1714,509,333 - 14,589,228 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1714,460,884 - 14,467,497 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01714,653,874 - 14,660,498 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1714,653,360 - 14,847,114 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11714,507,592 - 14,514,210 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01714,515,766 - 14,522,381 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01714,546,710 - 14,553,327 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Osr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629258,944,539 - 58,951,592 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649311,888,024 - 11,895,058 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493649311,888,024 - 11,895,058 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3118,757,920 - 118,765,102 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13118,368,471 - 118,765,107 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23126,839,630 - 126,845,239 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OSR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11488,364,115 - 88,371,258 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1488,364,166 - 88,371,263 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604523,861,885 - 23,869,038 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Osr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247382,136,151 - 2,138,441 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247382,136,228 - 2,559,092 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Osr1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1729,802,566 - 29,809,465 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Osr1
58 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:328
Count of miRNA genes:191
Interacting mature miRNAs:227
Transcripts:ENSRNOT00000005666
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63118500276185002Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)63332884178328841Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)63093763275937632Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)63332884178328841Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat

Markers in Region
Osr1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2632,380,204 - 32,380,355 (+)MAPPERmRatBN7.2
Rnor_6.0635,320,848 - 35,320,996NCBIRnor6.0
Rnor_5.0645,085,709 - 45,085,857UniSTSRnor5.0
RGSC_v3.4633,076,159 - 33,076,307UniSTSRGSC3.4
Celera631,816,378 - 31,816,526UniSTS
Cytogenetic Map6q14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
12 12 67 140 80 79 48 27 48 6 274 127 11 118 79 92 31 4 4

Sequence


Ensembl Acc Id: ENSRNOT00000005666   ⟹   ENSRNOP00000005666
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl638,093,011 - 38,100,009 (+)Ensembl
mRatBN7.2 Ensembl632,373,816 - 32,380,816 (+)Ensembl
Rnor_6.0 Ensembl635,314,444 - 35,321,667 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104721   ⟹   ENSRNOP00000085278
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl638,093,212 - 38,100,021 (+)Ensembl
mRatBN7.2 Ensembl632,377,537 - 32,380,817 (+)Ensembl
RefSeq Acc Id: NM_001106716   ⟹   NP_001100186
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8638,097,651 - 38,100,010 (+)NCBI
mRatBN7.2632,378,456 - 32,380,817 (+)NCBI
Dahl_SR_JrHsd639,540,575 - 39,542,934 (+)NCBI
Lyon_Normotensive638,976,881 - 38,979,240 (+)NCBI
Lyon_Hypertensive636,772,699 - 36,775,058 (+)NCBI
F344_StmMcwi635,989,654 - 35,992,025 (+)NCBI
Rnor_6.0635,319,099 - 35,321,458 (+)NCBI
Rnor_5.0645,074,989 - 45,086,319 (+)NCBI
RGSC_v3.4633,074,410 - 33,076,769 (+)RGD
Celera631,814,629 - 31,816,988 (+)RGD
Sequence:
RefSeq Acc Id: XM_039111941   ⟹   XP_038967869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8638,088,688 - 38,100,010 (+)NCBI
mRatBN7.2632,369,561 - 32,380,822 (+)NCBI
RefSeq Acc Id: XM_063261645   ⟹   XP_063117715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8638,092,956 - 38,100,010 (+)NCBI
RefSeq Acc Id: XM_063261646   ⟹   XP_063117716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8638,092,957 - 38,100,010 (+)NCBI
RefSeq Acc Id: NP_001100186   ⟸   NM_001106716
- UniProtKB: B0K011 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000005666   ⟸   ENSRNOT00000005666
RefSeq Acc Id: XP_038967869   ⟸   XM_039111941
- Peptide Label: isoform X1
- UniProtKB: B0K011 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000085278   ⟸   ENSRNOT00000104721
RefSeq Acc Id: XP_063117715   ⟸   XM_063261645
- Peptide Label: isoform X2
- UniProtKB: A0A8L2Q278 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117716   ⟸   XM_063261646
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0K011-F1-model_v2 AlphaFold B0K011 1-266 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694492
Promoter ID:EPDNEW_R5015
Type:multiple initiation site
Name:Osr1_1
Description:odd-skipped related transciption factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0635,314,463 - 35,314,523EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311807 AgrOrtholog
BioCyc Gene G2FUF-38164 BioCyc
Ensembl Genes ENSRNOG00000004210 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000005666 ENTREZGENE
  ENSRNOT00000104721 ENTREZGENE
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:8366695 IMAGE-MGC_LOAD
InterPro C2H2-ZF_Transcription_Reg UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report rno:298878 UniProtKB/Swiss-Prot
MGC_CLONE MGC:188687 IMAGE-MGC_LOAD
NCBI Gene 298878 ENTREZGENE
PANTHER ODD-SKIPPED - RELATED UniProtKB/Swiss-Prot
  PROTEIN ODD-SKIPPED-RELATED 1 UniProtKB/Swiss-Prot
Pfam zf-C2H2 UniProtKB/Swiss-Prot
PhenoGen Osr1 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000004210 RatGTEx
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt A0A8I5ZZT8_RAT UniProtKB/TrEMBL
  A0A8L2Q278 ENTREZGENE
  B0K011 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-12-04 Osr1  odd-skipped related transcription factor 1  Osr1  odd-skipped related transciption factor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-11-19 Osr1  odd-skipped related transciption factor 1  Osr1  odd-skipped related 1 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Osr1  odd-skipped related 1 (Drosophila)   Osr1_predicted  odd-skipped related 1 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Osr1_predicted  odd-skipped related 1 (Drosophila) (predicted)      Symbol and Name updated 1299863 APPROVED
2006-03-28 Osr1_predicted    Odd1_predicted  odd-skipped related 1 (Drosophila) (predicted)  Symbol updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-01-12 Odd1_predicted  odd-skipped related 1 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED