Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Usp6nl | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | USP6NL (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of USP6NL mRNA | CTD | PMID:22079256 | Usp6nl | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Usp6nl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of USP6NL mRNA | CTD | PMID:36331819 | Usp6nl | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of USP6NL mRNA | CTD | PMID:22206623 | Usp6nl | Rat | 17beta-estradiol | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Estradiol results in increased expression of USP6NL mRNA | CTD | PMID:39298647 | Usp6nl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of USP6NL mRNA | CTD | PMID:19465110|PMID:19770486 | Usp6nl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of USP6NL mRNA | CTD | PMID:33387578 | Usp6nl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of USP6NL mRNA | CTD | PMID:28922406 | Usp6nl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Usp6nl (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression more ... | CTD | PMID:25975270 | Usp6nl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Usp6nl (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of USP6NL mRNA | CTD | PMID:21570461 | Usp6nl | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of USP6NL mRNA | CTD | PMID:30851411 | Usp6nl | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of USP6NL mRNA | CTD | PMID:20188158 | Usp6nl | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | bisphenol S results in increased expression of USP6NL mRNA | CTD | PMID:39298647 | Usp6nl | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Usp6nl (Mus musculus) | 6480464 | bisphenol S affects the methylation of USP6NL gene | CTD | PMID:31683443 | Usp6nl | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Fenretinide results in increased expression of USP6NL mRNA | CTD | PMID:28973697 | Usp6nl | Rat | aflatoxin B1 | decreases methylation | ISO | USP6NL (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of USP6NL gene | CTD | PMID:27153756 | Usp6nl | Rat | all-trans-retinoic acid | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of USP6NL mRNA | CTD | PMID:33167477 | Usp6nl | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of USP6NL mRNA | CTD | PMID:30779732 | Usp6nl | Rat | aristolochic acid A | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of USP6NL mRNA | CTD | PMID:33212167 | Usp6nl | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of USP6NL gene | CTD | PMID:35440735 | Usp6nl | Rat | benzo[a]pyrene | multiple interactions | ISO | Usp6nl (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of USP6NL mRNA] | CTD | PMID:22228805 | Usp6nl | Rat | benzo[a]pyrene | affects methylation | ISO | USP6NL (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of USP6NL intron; Benzo(a)pyrene affects the methylation of USP6NL promoter | CTD | PMID:27901495|PMID:30157460 | Usp6nl | Rat | benzo[a]pyrene | decreases methylation | ISO | Usp6nl (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of USP6NL intron | CTD | PMID:27901495 | Usp6nl | Rat | benzo[a]pyrene | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of USP6NL mRNA | CTD | PMID:22228805 | Usp6nl | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of USP6NL mRNA | CTD | PMID:25181051 | Usp6nl | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of USP6NL mRNA | CTD | PMID:41034487 | Usp6nl | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of USP6NL mRNA | CTD | PMID:34947998 | Usp6nl | Rat | bisphenol A | multiple interactions | ISO | USP6NL (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of USP6NL gene | CTD | PMID:31601247 | Usp6nl | Rat | bisphenol F | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | bisphenol F results in increased expression of USP6NL mRNA | CTD | PMID:38685157 | Usp6nl | Rat | cadmium atom | multiple interactions | ISO | Usp6nl (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of USP6NL more ... | CTD | PMID:37236586|PMID:37325564 | Usp6nl | Rat | cadmium dichloride | multiple interactions | ISO | Usp6nl (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of USP6NL more ... | CTD | PMID:37236586|PMID:37325564 | Usp6nl | Rat | caffeine | affects phosphorylation | ISO | USP6NL (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of USP6NL protein | CTD | PMID:35688186 | Usp6nl | Rat | calcitriol | increases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Calcitriol results in increased expression of USP6NL mRNA | CTD | PMID:16002434 | Usp6nl | Rat | chlorpyrifos | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of USP6NL mRNA | CTD | PMID:37019170 | Usp6nl | Rat | cyclosporin A | increases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of USP6NL mRNA | CTD | PMID:25562108 | Usp6nl | Rat | deguelin | increases expression | ISO | USP6NL (Homo sapiens) | 6480464 | deguelin results in increased expression of USP6NL mRNA | CTD | PMID:33512557 | Usp6nl | Rat | Dibutyl phosphate | affects expression | ISO | USP6NL (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of USP6NL mRNA | CTD | PMID:37042841 | Usp6nl | Rat | dorsomorphin | multiple interactions | ISO | USP6NL (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Usp6nl | Rat | doxorubicin | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of USP6NL mRNA | CTD | PMID:29803840 | Usp6nl | Rat | epoxiconazole | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | epoxiconazole results in increased expression of USP6NL mRNA | CTD | PMID:35436446 | Usp6nl | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of USP6NL mRNA | CTD | PMID:30307764 | Usp6nl | Rat | folic acid | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Folic Acid results in decreased expression of USP6NL mRNA | CTD | PMID:25629700 | Usp6nl | Rat | formaldehyde | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of USP6NL mRNA | CTD | PMID:20655997 | Usp6nl | Rat | FR900359 | affects phosphorylation | ISO | USP6NL (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of USP6NL protein | CTD | PMID:37730182 | Usp6nl | Rat | fulvestrant | multiple interactions | ISO | USP6NL (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of USP6NL gene | CTD | PMID:31601247 | Usp6nl | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of USP6NL mRNA | CTD | PMID:33387578 | Usp6nl | Rat | hydrogen peroxide | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Hydrogen Peroxide results in decreased expression of USP6NL mRNA | CTD | PMID:37149095 | Usp6nl | Rat | lead diacetate | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | lead acetate results in decreased expression of USP6NL mRNA | CTD | PMID:22613225 | Usp6nl | Rat | leflunomide | increases expression | ISO | USP6NL (Homo sapiens) | 6480464 | leflunomide results in increased expression of USP6NL mRNA | CTD | PMID:28988120 | Usp6nl | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of USP6NL gene | CTD | PMID:35440735 | Usp6nl | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of USP6NL mRNA | CTD | PMID:25729387 | Usp6nl | Rat | paracetamol | affects expression | ISO | Usp6nl (Mus musculus) | 6480464 | Acetaminophen affects the expression of USP6NL mRNA | CTD | PMID:17562736 | Usp6nl | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of USP6NL mRNA | CTD | PMID:33387578 | Usp6nl | Rat | paracetamol | multiple interactions | ISO | Usp6nl (Mus musculus) | 6480464 | MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of USP6NL mRNA] | CTD | PMID:18700144 | Usp6nl | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Usp6nl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of USP6NL mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Usp6nl | Rat | phenobarbital | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of USP6NL mRNA | CTD | PMID:19270015 | Usp6nl | Rat | phenobarbital | affects expression | ISO | Usp6nl (Mus musculus) | 6480464 | Phenobarbital affects the expression of USP6NL mRNA | CTD | PMID:23091169 | Usp6nl | Rat | potassium chromate | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of USP6NL mRNA | CTD | PMID:22079256 | Usp6nl | Rat | potassium chromate | multiple interactions | ISO | USP6NL (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of USP6NL mRNA | CTD | PMID:22079256 | Usp6nl | Rat | propiconazole | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | propiconazole results in decreased expression of USP6NL mRNA | CTD | PMID:21278054 | Usp6nl | Rat | quercetin | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Quercetin results in decreased expression of USP6NL mRNA; Quercetin results in decreased expression of USP6NL more ... | CTD | PMID:19207037|PMID:21632981 | Usp6nl | Rat | rac-lactic acid | decreases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of USP6NL mRNA | CTD | PMID:30851411 | Usp6nl | Rat | resveratrol | multiple interactions | ISO | USP6NL (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of USP6NL mRNA | CTD | PMID:23557933 | Usp6nl | Rat | SB 431542 | multiple interactions | ISO | USP6NL (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Usp6nl | Rat | sodium arsenate | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of USP6NL mRNA | CTD | PMID:21795629|PMID:39847705 | Usp6nl | Rat | sodium arsenite | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | sodium arsenite results in increased expression of USP6NL mRNA | CTD | PMID:16014739 | Usp6nl | Rat | tetrachloromethane | affects expression | ISO | Usp6nl (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of USP6NL mRNA | CTD | PMID:17484886 | Usp6nl | Rat | tetrachloromethane | increases expression | ISO | Usp6nl (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of USP6NL mRNA | CTD | PMID:31919559 | Usp6nl | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of USP6NL mRNA | CTD | PMID:31150632 | Usp6nl | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of USP6NL mRNA | CTD | PMID:25729387 | Usp6nl | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of USP6NL mRNA | CTD | PMID:25729387 | Usp6nl | Rat | troglitazone | decreases expression | ISO | Usp6nl (Mus musculus) | 6480464 | troglitazone results in decreased expression of USP6NL mRNA | CTD | PMID:28973697 | Usp6nl | Rat | valproic acid | decreases methylation | ISO | USP6NL (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of USP6NL gene | CTD | PMID:29154799 | Usp6nl | Rat | valproic acid | increases expression | ISO | USP6NL (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of USP6NL mRNA | CTD | PMID:23179753|PMID:24383497|PMID:24935251|PMID:25192806|PMID:26272509|PMID:28001369|PMID:29154799 | Usp6nl | Rat | valproic acid | multiple interactions | ISO | USP6NL (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















