Arrdc4 (arrestin domain containing 4) - Rat Genome Database

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Gene: Arrdc4 (arrestin domain containing 4) Rattus norvegicus
Analyze
Symbol: Arrdc4
Name: arrestin domain containing 4
RGD ID: 1311763
Description: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in extracellular vesicle biogenesis; protein transport; and protein ubiquitination. Predicted to act upstream of or within positive regulation of interferon-beta production and protein K63-linked ubiquitination. Predicted to be located in endosome; extracellular vesicle; and plasma membrane. Orthologous to human ARRDC4 (arrestin domain containing 4); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Ab1-209; arrestin domain-containing protein 4; liver regeneration-related protein LRRG041/LRRGT00117; LOC293019; LRRG00117
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81131,779,436 - 131,793,438 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1131,779,437 - 131,793,565 (-)EnsemblGRCr8
mRatBN7.21122,369,355 - 122,383,351 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1122,369,360 - 122,383,290 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1130,366,117 - 130,380,105 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01137,536,216 - 137,550,204 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01130,337,167 - 130,351,155 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01129,766,097 - 129,780,076 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1129,766,100 - 129,780,356 (-)Ensemblrn6Rnor6.0
Rnor_5.01130,819,069 - 130,833,129 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41123,522,706 - 123,531,698 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1114,557,876 - 114,566,923 (-)NCBICelera
RGSC_v3.11123,602,320 - 123,613,916 (-)NCBI
Cytogenetic Map1q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
ampicillin  (ISO)
antimycin A  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
azoxystrobin  (ISO)
benzethonium chloride  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
Benzo[k]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
deguelin  (ISO)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diethyl maleate  (ISO)
diethyl phthalate  (ISO)
difenoconazole  (EXP)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
esketamine  (ISO)
ethanol  (ISO)
fenpyroximate  (ISO)
fluoranthene  (ISO)
flusilazole  (EXP)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
iron dichloride  (ISO)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (ISO)
N(4)-hydroxycytidine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel dichloride  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
parathion  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenformin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (EXP)
pyrimidifen  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
tebufenpyrad  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thifluzamide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:23236378   PMID:27462458  


Genomics

Comparative Map Data
Arrdc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81131,779,436 - 131,793,438 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1131,779,437 - 131,793,565 (-)EnsemblGRCr8
mRatBN7.21122,369,355 - 122,383,351 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1122,369,360 - 122,383,290 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1130,366,117 - 130,380,105 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01137,536,216 - 137,550,204 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01130,337,167 - 130,351,155 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01129,766,097 - 129,780,076 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1129,766,100 - 129,780,356 (-)Ensemblrn6Rnor6.0
Rnor_5.01130,819,069 - 130,833,129 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41123,522,706 - 123,531,698 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1114,557,876 - 114,566,923 (-)NCBICelera
RGSC_v3.11123,602,320 - 123,613,916 (-)NCBI
Cytogenetic Map1q22NCBI
ARRDC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381597,960,703 - 97,973,833 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1597,960,703 - 97,973,838 (+)Ensemblhg38GRCh38
GRCh371598,503,933 - 98,517,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361596,304,947 - 96,318,064 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341596,304,951 - 96,318,064NCBI
Celera1574,920,256 - 74,933,391 (+)NCBICelera
Cytogenetic Map15q26.2NCBI
HuRef1574,633,884 - 74,647,021 (+)NCBIHuRef
CHM1_11598,345,926 - 98,359,059 (+)NCBICHM1_1
T2T-CHM13v2.01595,726,358 - 95,739,492 (+)NCBIT2T-CHM13v2.0
Arrdc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39768,386,742 - 68,398,986 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl768,386,743 - 68,398,989 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38768,736,994 - 68,749,238 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl768,736,995 - 68,749,241 (-)Ensemblmm10GRCm38
MGSCv37775,881,880 - 75,894,124 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36768,615,124 - 68,622,716 (-)NCBIMGSCv36mm8
Celera766,193,576 - 66,206,534 (-)NCBICelera
Cytogenetic Map7CNCBI
cM Map737.81NCBI
Arrdc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541625,573,265 - 25,587,127 (+)Ensembl
ChiLan1.0NW_00495541625,573,265 - 25,583,928 (+)NCBIChiLan1.0ChiLan1.0
ARRDC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21687,505,885 - 87,519,147 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11591,202,496 - 91,215,647 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01576,643,796 - 76,657,525 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11595,830,793 - 95,843,939 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1595,830,793 - 95,843,939 (+)EnsemblpanPan2panpan1.1
ARRDC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1342,650,257 - 42,663,526 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl342,652,728 - 42,664,401 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha345,351,735 - 45,364,995 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0343,060,856 - 43,074,118 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl343,060,868 - 43,074,103 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1342,584,579 - 42,597,841 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0342,816,780 - 42,830,047 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0343,037,496 - 43,050,757 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arrdc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640140,932,378 - 140,945,035 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364835,389,422 - 5,402,076 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364835,389,448 - 5,401,995 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARRDC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl781,656,761 - 81,669,509 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1781,656,760 - 81,669,584 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2787,586,099 - 87,598,949 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARRDC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12916,536,541 - 16,551,386 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2916,538,408 - 16,548,743 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605930,040,508 - 30,053,676 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arrdc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247686,248,082 - 6,260,600 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Arrdc4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v12131,575,061 - 131,588,417 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Arrdc4
95 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:30
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000051402
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1131179947176179947Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1101228864146228864Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130419227175419227Rat
631684Bp117Blood pressure QTL 1178.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1120082258165082258Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1112521556157521556Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1130419227175419227Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1127329268206393015Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1109493780193400781Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1110389869155389869Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1124975316152612788Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1110389869155389869Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1116099376191260518Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1101594089146594089Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1131243790176243790Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1111404407142582336Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1129182274174182274Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1115183611176289080Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1111949780210707719Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1128019551173019551Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)1108680016153680016Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1102359314153680016Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1111949780210707719Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1112521556157521556Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1111949780160574007Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1100345976145345976Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1111949780228180370Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 91 59 6 355 191 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000051402   ⟹   ENSRNOP00000045721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1129,767,230 - 129,776,276 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077479   ⟹   ENSRNOP00000073183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1131,779,437 - 131,793,565 (-)Ensembl
mRatBN7.2 Ensembl1122,369,360 - 122,383,290 (-)Ensembl
Rnor_6.0 Ensembl1129,766,100 - 129,780,356 (-)Ensembl
RefSeq Acc Id: NM_001393761   ⟹   NP_001380690
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81131,779,437 - 131,793,425 (-)NCBI
mRatBN7.21122,369,358 - 122,383,346 (-)NCBI
RefSeq Acc Id: XM_006229368   ⟹   XP_006229430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81131,779,436 - 131,793,438 (-)NCBI
mRatBN7.21122,369,355 - 122,383,351 (-)NCBI
Rnor_6.01129,766,718 - 129,780,076 (-)NCBI
Rnor_5.01130,819,069 - 130,833,129 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001380690 (Get FASTA)   NCBI Sequence Viewer  
  XP_006229430 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP92552 (Get FASTA)   NCBI Sequence Viewer  
  AAS66208 (Get FASTA)   NCBI Sequence Viewer  
  EDM08482 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000073183
GenBank Protein Q7TP90 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_006229430   ⟸   XM_006229368
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000073183   ⟸   ENSRNOT00000077479
Ensembl Acc Id: ENSRNOP00000045721   ⟸   ENSRNOT00000051402
RefSeq Acc Id: NP_001380690   ⟸   NM_001393761
- UniProtKB: A0A0G2K4V0 (UniProtKB/TrEMBL),   A6JBV5 (UniProtKB/TrEMBL)
Protein Domains
Arrestin C-terminal-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TP90-F1-model_v2 AlphaFold Q7TP90 1-300 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311763 AgrOrtholog
BioCyc Gene G2FUF-58951 BioCyc
Ensembl Genes ENSRNOG00000010775 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000077479 ENTREZGENE
Gene3D-CATH 2.60.40.640 UniProtKB/Swiss-Prot
InterPro Arrestin-like_N UniProtKB/Swiss-Prot
  Arrestin_C UniProtKB/Swiss-Prot
  Arrestin_C-like UniProtKB/Swiss-Prot
  Arrestin_domain-protein UniProtKB/Swiss-Prot
  Ig_E-set UniProtKB/Swiss-Prot
NCBI Gene 293019 ENTREZGENE
PANTHER ARRESTIN DOMAIN CONTAINING PROTEIN UniProtKB/Swiss-Prot
  ARRESTIN DOMAIN-CONTAINING PROTEIN 4 UniProtKB/Swiss-Prot
Pfam Arrestin_C UniProtKB/Swiss-Prot
  Arrestin_N UniProtKB/Swiss-Prot
PhenoGen Arrdc4 PhenoGen
RatGTEx ENSRNOG00000010775 RatGTEx
SMART Arrestin_C UniProtKB/Swiss-Prot
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot
UniProt A0A0G2K4V0 ENTREZGENE, UniProtKB/TrEMBL
  A6JBV5 ENTREZGENE, UniProtKB/TrEMBL
  ARRD4_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Arrdc4  arrestin domain containing 4  Arrdc4_predicted  arrestin domain containing 4 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Arrdc4_predicted  arrestin domain containing 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED