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Gene: Tead3 (TEA domain transcription factor 3) Rattus norvegicus

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Symbol:

Tead3

Name:

TEA domain transcription factor 3

RGD ID:

1311583

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including asymmetric neuroblast division; hippo signaling; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of stem cell population maintenance and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Orthologous to human TEAD3 (TEA domain transcription factor 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

LOC294299; TEA domain family member 3; transcriptional enhancer factor TEF-5

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TEAD3 (TEA domain transcription factor 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Tead3 (TEA domain family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tead3 (TEA domain transcription factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TEAD3 (TEA domain transcription factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TEAD3 (TEA domain transcription factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tead3 (TEA domain transcription factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TEAD3 (TEA domain transcription factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TEAD3 (TEA domain transcription factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tead3 (TEA domain transcription factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Tead3 (TEA domain transcription factor 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TEAD3 (TEA domain transcription factor 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tead3 (TEA domain family member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tead3b (TEA domain family member 3 b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tead3b (TEA domain family member 3 b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	tead3a (TEA domain family member 3 a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tead3a (TEA domain family member 3 a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	egl-44	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	egl-44	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	TEC1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	TEC1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	sd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	sd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	6,393,786 - 6,413,177 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	6,393,786 - 6,413,174 (-)	Ensembl				GRCr8
mRatBN7.2	20	6,392,053 - 6,411,446 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	6,392,053 - 6,411,446 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	7,104,678 - 7,124,077 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	6,466,508 - 6,485,905 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	6,945,984 - 6,965,360 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	7,911,562 - 7,930,949 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	7,908,226 - 7,930,929 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	10,111,923 - 10,131,306 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	6,572,336 - 6,591,723 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	7,948,439 - 7,967,826 (-)	NCBI		Celera
RGSC_v3.1	20	6,572,541 - 6,592,859 (-)	NCBI
Cytogenetic Map	20	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-hydroxypropanoic acid (ISO)

4,4'-sulfonyldiphenol (ISO)

acrylamide (EXP,ISO)

actinomycin D (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

chloroprene (EXP)

choline (ISO)

cisplatin (ISO)

Cuprizon (EXP)

elemental selenium (ISO)

endosulfan (EXP)

folic acid (ISO)

FR900359 (ISO)

genistein (ISO)

gentamycin (EXP)

glycidol (EXP)

L-methionine (ISO)

niclosamide (ISO)

Nor-9-carboxy-delta9-THC (ISO)

Nutlin-3 (ISO)

paracetamol (ISO)

PCB138 (EXP)

pirinixic acid (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

selenium atom (ISO)

selenomethionine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (EXP,ISO)

zearalenone (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

asymmetric neuroblast division (ISO)

DNA-templated transcription (IEA)

embryonic organ development (IBA)

hippo signaling (IBA,IEA,ISO)

positive regulation of stem cell population maintenance (ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

nucleus (IEA)

transcription regulator complex (IBA,ISO)

Molecular Function

DNA binding (IEA,ISO)

DNA-binding transcription factor activity (IEA,ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:9502435	PMID:12477932	PMID:16207754	PMID:18579750	PMID:19324877	PMID:20516196	PMID:23946438

Genomics

Comparative Map Data

Tead3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	6,393,786 - 6,413,177 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	6,393,786 - 6,413,174 (-)	Ensembl				GRCr8
mRatBN7.2	20	6,392,053 - 6,411,446 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	6,392,053 - 6,411,446 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	7,104,678 - 7,124,077 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	6,466,508 - 6,485,905 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	6,945,984 - 6,965,360 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	7,911,562 - 7,930,949 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	7,908,226 - 7,930,929 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	10,111,923 - 10,131,306 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	6,572,336 - 6,591,723 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	7,948,439 - 7,967,826 (-)	NCBI		Celera
RGSC_v3.1	20	6,572,541 - 6,592,859 (-)	NCBI
Cytogenetic Map	20	p12	NCBI

TEAD3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	35,473,597 - 35,497,079 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	35,473,597 - 35,497,079 (-)	Ensembl			hg38	GRCh38
GRCh37	6	35,441,374 - 35,464,856 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	35,549,352 - 35,572,839 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	35,549,353 - 35,572,763	NCBI
Celera	6	36,995,352 - 37,018,841 (-)	NCBI		Celera
Cytogenetic Map	6	p21.31	NCBI
HuRef	6	35,162,129 - 35,185,618 (-)	NCBI		HuRef
CHM1_1	6	35,443,385 - 35,466,891 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	6	35,296,673 - 35,320,158 (-)	NCBI		T2T-CHM13v2.0

Tead3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	28,550,645 - 28,569,779 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	28,550,645 - 28,569,791 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	28,331,671 - 28,350,805 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	28,331,671 - 28,350,817 (-)	Ensembl			mm10	GRCm38
MGSCv37	17	28,468,620 - 28,487,750 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	28,059,260 - 28,077,735 (-)	NCBI		MGSCv36	mm8
Celera	17	28,885,499 - 28,904,627 (-)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	14.66	NCBI

Tead3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	3,387,228 - 3,405,069 (-)	Ensembl
ChiLan1.0	NW_004955437	3,387,812 - 3,405,232 (-)	NCBI	ChiLan1.0	ChiLan1.0

TEAD3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	49,940,007 - 49,963,568 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	45,804,899 - 45,832,359 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	35,034,138 - 35,057,644 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	36,127,219 - 36,150,620 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	36,127,219 - 36,140,360 (-)	Ensembl			panPan2	panpan1.1

TEAD3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	12	4,610,663 - 4,627,817 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	12	4,611,144 - 4,632,888 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	12	4,626,143 - 4,648,061 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	12	4,948,482 - 4,970,954 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	12	4,948,507 - 4,969,873 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	12	4,609,226 - 4,631,461 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	12	4,687,985 - 4,710,121 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	12	4,788,248 - 4,810,321 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tead3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	40,182,635 - 40,195,083 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936476	23,766,012 - 23,779,349 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936476	23,766,021 - 23,776,785 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TEAD3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	31,336,560 - 31,361,835 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	31,337,890 - 31,351,452 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	36,072,129 - 36,100,663 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TEAD3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	36,626,528 - 36,651,367 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	36,637,113 - 36,651,752 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666044	35,385,138 - 35,410,436 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tead3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	21,971,445 - 21,986,557 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624754	21,971,362 - 21,987,128 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tead3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	5,508,992 - 5,528,877 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tead3
126 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	172
Count of miRNA genes:	117
Interacting mature miRNAs:	140
Transcripts:	ENSRNOT00000000607
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	4189476	49189476	Rat
61474	Eae1	Experimental allergic encephalomyelitis QTL 1	3		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	20	1	6693431	Rat
2317057	Aia27	Adjuvant induced arthritis QTL 27	2.83		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	20	1	26925056	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	1	33724594	Rat
7387283	Uae44	Urinary albumin excretion QTL 44		0.1712	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	20	1	26128279	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	36600300	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	1533083	46533083	Rat
1354642	Despr15	Despair related QTL 15		0.0027	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	20	1	24164241	Rat
1558640	Prcs2	Prostate cancer susceptibility QTL 2	3.3		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	20	1	34066551	Rat
1331772	Cdexp2	CD45RC expression in CD8 T cells QTL 2	5.7		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	20	3626323	10078622	Rat
8694189	Bw153	Body weight QTL 153	3.13	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	20	1	29193376	Rat
70154	Insul2	Insulin level QTL 2	3.75		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	6693431	Rat
4889857	Pur27	Proteinuria QTL 27	12.2	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	1	27341128	Rat
1300152	Bp195	Blood pressure QTL 195	3.46		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	20	3626323	9244918	Rat
9590109	Sffal8	Serum free fatty acids level QTL 8	5.32	0.01	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	20	1	29193376	Rat
9589155	Insul32	Insulin level QTL 32	6.38	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	20	1	29193376	Rat
9590275	Scort15	Serum corticosterone level QTL 15	3.48	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	29193376	Rat
7411650	Foco23	Food consumption QTL 23	20.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	29193376	Rat
61432	Cia1	Collagen induced arthritis QTL 1			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	20	1	14100378	Rat
2317851	Alcrsp22	Alcohol response QTL 22	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
1641893	Alcrsp7	Alcohol response QTL 7			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	1	27341128	Rat
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	32578510	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	36600300	Rat

Markers in Region

AW125760

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	20	6,393,901 - 6,394,053 (+)	Marker Load Pipeline
mRatBN7.2	20	6,392,168 - 6,392,319 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	7,911,678 - 7,911,828	NCBI	Rnor6.0
Rnor_5.0	20	10,112,039 - 10,112,189	UniSTS	Rnor5.0
RGSC_v3.4	20	6,572,452 - 6,572,602	UniSTS	RGSC3.4
Celera	20	7,948,555 - 7,948,705	UniSTS
Cytogenetic Map	20	p12	UniSTS

RH128061

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	20	6,412,176 - 6,412,356 (+)	MAPPER	mRatBN7.2
Rnor_6.0	20	7,931,680 - 7,931,859	NCBI	Rnor6.0
Rnor_5.0	20	10,132,037 - 10,132,216	UniSTS	Rnor5.0
RGSC_v3.4	20	6,592,454 - 6,592,633	UniSTS	RGSC3.4
Celera	20	7,968,557 - 7,968,736	UniSTS
RH 3.4 Map	20	76.13	UniSTS
Cytogenetic Map	20	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	156	91	90	59	54	59	6	318	154	11	135	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001098216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC106225	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC085938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC099077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BF418871	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000000607 ⟹ ENSRNOP00000000607

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	6,393,786 - 6,403,236 (-)	Ensembl
mRatBN7.2 Ensembl	20	6,392,053 - 6,411,446 (-)	Ensembl
Rnor_6.0 Ensembl	20	7,908,226 - 7,930,929 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096677 ⟹ ENSRNOP00000084959

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	6,393,786 - 6,412,988 (-)	Ensembl
mRatBN7.2 Ensembl	20	6,392,053 - 6,411,446 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107495 ⟹ ENSRNOP00000097248

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	6,393,786 - 6,412,988 (-)	Ensembl
mRatBN7.2 Ensembl	20	6,392,053 - 6,411,244 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000158735 ⟹ ENSRNOP00000110655

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	20	6,393,786 - 6,413,174 (-)	Ensembl

RefSeq Acc Id:

NM_001098216 ⟹ NP_001091686

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	20	6,393,786 - 6,413,177 (-)	NCBI
mRatBN7.2	20	6,392,053 - 6,411,446 (-)	NCBI
Rnor_6.0	20	7,911,562 - 7,930,949 (-)	NCBI
Rnor_5.0	20	10,111,923 - 10,131,306 (-)	NCBI
RGSC_v3.4	20	6,572,336 - 6,591,723 (-)	RGD
Celera	20	7,948,439 - 7,967,826 (-)	RGD

Sequence:

show sequence

GGCTCCCTCAACACAAACTTTCCGTCCCGCTCGCTCCCTCCTCCGCGCCCAGCACCTCCCGCTC
CGGCCCGGCTCATTCCGTACATTCCGGCCATCCCCCTGCCCACGACCCCCCTTCCCGGCCCCCC
TTACTACTCCCTCGGGCCCGGCGGAGCGGCCCGGCGGAGCGCCCCCCGGAGCTCGGAGCAGGCT
CAGGCCATCCAGGGGGCTCAGGCCCAGAGCCCAGAGCAACCAGCACAATAGCGTCCAACAGCTG
GACCGCCAACAACAGCCCCGGGGAGGCCCGGGAAGATGGGTCCGAGGGCCTGGATAAAGGGCTG
GACAACGATGCCGAGGGAGTGTGGAGCCCAGACATCGAGCAGAGCTTTCAGGAGGCCCTGGCCA
TCTACCCGCCTTGTGGCCGGCGCAAGATCATCCTGTCGGATGAGGGCAAGATGTACGGTCGAAA
TGAGCTGATTGCCCGATACATCAAGCTGAGGACTGGAAAAACCAGGACGAGAAAACAGGTGTCC
AGCCACATACAGGTTCTAGCTCGGAAGAAGGTTCGGGAATACCAGGTTGGCATTAAGGCTATGA
ACCTGGACCAGGTCTCCAAGGACAAAGCTCTTCAGAGCATGGCATCTATGTCGTCTGCCCAAAT
CGTCTCTGCCAGCGTCCTACAGAACAAGTTCAGCCCACCCTCCCCTCTGCCCCAGGCTGTCTTC
TCCACCTCAAGGTTCTGGAGCAGCCCCCCTCTGCTAGGACAACAGCCTGGACCGTCTCAGGACA
TCAAGCCCTTTGCACAGCCTGCCTACCCCATCCAGCCTCCCCTGCCGCCAACACTCAATAGTTA
TGAGTCCCTGGCCCCGCTGCCCCCAGCCGCTGCCACTGCTGCCTCCGTGCCTGCCTGGCAGGAC
CGCACCATCGCCTCCTCCCGGCTACGCCTCCTGGAGTATTCTGCCTTCATGGAGGTGCAAAGGG
ACCCCGACACGTACAGCAAACACCTGTTTGTACACATCGGCCAGACAAACCCTGCCTTCTCAGA
CCCACCCCTGGAGGCAGTGGATGTTCGCCAGATCTACGACAAGTTCCCCGAGAAGAAAGGGGGG
CTGAAGGAGCTCTACGAGAAAGGGCCCCCCAATGCCTTCTTCCTTGTCAAGTTCTGGGCTGACC
TCAACAGCACAATCCAGGAAGGCCCTGGGGCCTTCTACGGGGTCAGCTCACAGTACAGCTCGGC
GGACAGCATGACCATCAGTGTCTCCACCAAGGTGTGTTCCTTCGGCAAGCAGGTGGTAGAGAAA
GTAGAGACAGAGTATGCCCGCCTGGAGAACGGCCGCTTTGTGTACCGCATCCACCGCTCACCCA
TGTGCGAGTACATGATCAACTTCATCCACAAGCTGAAGCACCTGCCCGAGAAGTACATGATGAA
CAGCGTGCTGGAGAACTTCACCATCCTGCAGGTGGTCACGAGTCGGGACTCGCAGGAGACCCTG
CTGGTCATTGCTTTTGTCTTTGAAGTGTCCACCAGTGAGCATGGGGCACAGCATCACGTCTACA
AGCTTGTGAAAGACTAGCATGCCCACAGGATGCAAGTCGGACCTCCTCCGAACACCTGCCTGCC
TGGTCTCCCTGGGTGTGGGTTGGGGGGACCTACCCACCCATGGGTTTCTTCAGGCTGGGACCTG
GGCTGCCTCCCTGGCCCCAGCACACACACTCCCTGCCACTGTTCTGCGCTTTACTGGAGAGAAG
AGGGCTCCACGGTGGGGTGGCTTGCCTGGGCACTGAGCCATAGATGACCTGGCCTCAGGTGATA
TCAGAATTGTACTATGGAGGACACCTTGGGGGCTTAGTGTGTTGTCCCTGGCCACTAGAGGAGT
GTGATGGGCAGGAGAGAGGGTAGCATTAAGACTAGGAAGAGACAGCTTGCAAGGAGGCCCTGGT
ACAAGGTGTCAAATTGGGGGATAGGTTGAGAAGGGCCTACACTTCTTCGGACCTTCTGGGTACC
AGCCCCTTAACACAGCAAGTCTGGGTCTCCTGAAAGTGCCAAGATGGAGGCCCCCAGAAGCAGA
CAGAGCTGGAGGCTGGGTTCAGCTACCTCCCCAGCAGAGCTGGGTGCTGGCAGGGAAGGGGCGT
GCTGTGGAATGGTACAGCTGGGCTGGAGCCTAGACAGGGTTCTACTTCCTGTTCTCCCAGTGTG
CTAGCCACTAGGCACCCCTCCCTCCATGTCCTGCAGACAGGTGGCAGGGAACAGGAGGCTGCCT
CTGCCTTCTCTACATCCAGGTCCCAAGGTCGCCTGGGTATTTATGAGTTTCAAATGAAGTACTG
TGCCCCTCCTCATCCAGCCCGAGCTCCCTGAAGGTCTTCACCATTGCATACTGCTCAGGCCACC
CCTAAACCCCACCTAGGTTTTATATCATGTATTATATATATTTTTGTGTATTTTTAAAATCCAG
CTGTGACGGGCTATATCGTAAATGGCTCTAAGGCAGGGGCCACTCAAGGCCTGGCTCCTGCTTA
AAAAAAAAAAAAAAATTAAAAAAAAAAAAGCTGTTTCTGGGTCAGGACAGTTGTGCCACATGAA
AAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001091686	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH85938	(Get FASTA)	NCBI Sequence Viewer
	AAH99077	(Get FASTA)	NCBI Sequence Viewer
	EDL96924	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000000607.9
	ENSRNOP00000084959.2
	ENSRNOP00000097248.2
	ENSRNOP00000110655.1

RefSeq Acc Id:

NP_001091686 ⟸ NM_001098216

- UniProtKB:

F7EPU7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASNSWTANNSPGEAREDGSEGLDKGLDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEG
KMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARKKVREYQVGIKAMNLDQVSKDKALQSMAS
MSSAQIVSASVLQNKFSPPSPLPQAVFSTSRFWSSPPLLGQQPGPSQDIKPFAQPAYPIQPPLP
PTLNSYESLAPLPPAAATAASVPAWQDRTIASSRLRLLEYSAFMEVQRDPDTYSKHLFVHIGQT
NPAFSDPPLEAVDVRQIYDKFPEKKGGLKELYEKGPPNAFFLVKFWADLNSTIQEGPGAFYGVS
SQYSSADSMTISVSTKVCSFGKQVVEKVETEYARLENGRFVYRIHRSPMCEYMINFIHKLKHLP
EKYMMNSVLENFTILQVVTSRDSQETLLVIAFVFEVSTSEHGAQHHVYKLVKD

hide sequence

Ensembl Acc Id:

ENSRNOP00000000607 ⟸ ENSRNOT00000000607

Ensembl Acc Id:

ENSRNOP00000097248 ⟸ ENSRNOT00000107495

Ensembl Acc Id:

ENSRNOP00000084959 ⟸ ENSRNOT00000096677

Ensembl Acc Id:

ENSRNOP00000110655 ⟸ ENSRNOT00000158735

Protein Domains

TEA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F7EPU7-F1-model_v2	AlphaFold	F7EPU7	1-372	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701461

Promoter ID:

EPDNEW_R11984

Type:

initiation region

Name:

Tead3_1

Description:

TEA domain transcription factor 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	7,930,937 - 7,930,997	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311583	AgrOrtholog
BioCyc Gene	G2FUF-4422	BioCyc
Ensembl Genes	ENSRNOG00000000506	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000000607.8	UniProtKB/TrEMBL
	ENSRNOT00000096677.2	UniProtKB/TrEMBL
	ENSRNOT00000107495.2	UniProtKB/TrEMBL
	ENSRNOT00000158735.1	UniProtKB/TrEMBL
Gene3D-CATH	2.70.50.80	UniProtKB/TrEMBL
	6.10.20.40	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7122897	IMAGE-MGC_LOAD
	IMAGE:7442271	IMAGE-MGC_LOAD
InterPro	TEA/ATTS	UniProtKB/TrEMBL
	TEA/ATTS_sf	UniProtKB/TrEMBL
	TEC1_TEAD_TF	UniProtKB/TrEMBL
	TEF	UniProtKB/TrEMBL
	TEF-5	UniProtKB/TrEMBL
	YBD	UniProtKB/TrEMBL
KEGG Report	rno:294299	UniProtKB/TrEMBL
MGC_CLONE	MGC:116105	IMAGE-MGC_LOAD
	MGC:95036	IMAGE-MGC_LOAD
NCBI Gene	294299	ENTREZGENE
PANTHER	TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED	UniProtKB/TrEMBL
	TRANSCRIPTIONAL ENHANCER FACTOR TEF-5	UniProtKB/TrEMBL
Pfam	TEA	UniProtKB/TrEMBL
	YBD	UniProtKB/TrEMBL
PhenoGen	Tead3	PhenoGen
PIRSF	TEF	UniProtKB/TrEMBL
	TEF-5	UniProtKB/TrEMBL
PRINTS	TEADOMAIN	UniProtKB/TrEMBL
PROSITE	TEA_1	UniProtKB/TrEMBL
	TEA_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000000506	RatGTEx
SMART	TEA	UniProtKB/TrEMBL
UniProt	A0A8I6A176_RAT	UniProtKB/TrEMBL
	A0A8I6GMF8_RAT	UniProtKB/TrEMBL
	A0ABK0M1I4_RAT	UniProtKB/TrEMBL
	A6JJQ8_RAT	UniProtKB/TrEMBL
	F7EPU7	ENTREZGENE, UniProtKB/TrEMBL
	Q4KLN9_RAT	UniProtKB/TrEMBL
	Q5U2N6_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-01-20	Tead3	TEA domain transcription factor 3	Tead3	TEA domain family member 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Tead3	TEA domain family member 3	Tead3_predicted	TEA domain family member 3 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Tead3_predicted	TEA domain family member 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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