Trim14 (tripartite motif-containing 14) - Rat Genome Database

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Gene: Trim14 (tripartite motif-containing 14) Rattus norvegicus
Analyze
Symbol: Trim14
Name: tripartite motif-containing 14
RGD ID: 1311514
Description: Predicted to enable transcription coactivator activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including innate immune response; negative regulation of viral transcription; and protein ubiquitination. Predicted to be active in cytoplasm. Orthologous to human TRIM14 (tripartite motif containing 14); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313236; tripartite motif protein 14; tripartite motif-containing protein 14
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,596,149 - 65,620,434 (-)NCBIGRCr8
mRatBN7.2560,800,568 - 60,824,858 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,800,032 - 60,824,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx562,771,575 - 62,795,820 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,590,946 - 64,615,185 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,560,355 - 64,584,600 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0562,128,941 - 62,154,424 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl562,128,941 - 62,153,786 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0566,656,500 - 66,681,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4563,092,632 - 63,118,519 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1563,095,090 - 63,119,006 (-)NCBI
Celera559,361,648 - 59,386,439 (-)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
glafenine  (EXP)
glycidol  (EXP)
hydrogen peroxide  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
menadione  (ISO)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
nickel atom  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
parathion  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triptonide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11331580   PMID:12477932   PMID:16751776   PMID:16778019   PMID:18248090   PMID:23077300   PMID:33691569   PMID:37503784   PMID:37951197  


Genomics

Comparative Map Data
Trim14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8565,596,149 - 65,620,434 (-)NCBIGRCr8
mRatBN7.2560,800,568 - 60,824,858 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl560,800,032 - 60,824,858 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx562,771,575 - 62,795,820 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0564,590,946 - 64,615,185 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0564,560,355 - 64,584,600 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0562,128,941 - 62,154,424 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl562,128,941 - 62,153,786 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0566,656,500 - 66,681,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4563,092,632 - 63,118,519 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1563,095,090 - 63,119,006 (-)NCBI
Celera559,361,648 - 59,386,439 (-)NCBICelera
Cytogenetic Map5q22NCBI
TRIM14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38998,035,797 - 98,119,222 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl998,069,275 - 98,119,222 (-)EnsemblGRCh38hg38GRCh38
GRCh379100,846,635 - 100,881,504 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36999,871,384 - 99,921,309 (-)NCBINCBI36Build 36hg18NCBI36
Celera971,345,840 - 71,395,772 (-)NCBICelera
Cytogenetic Map9q22.33NCBI
HuRef970,431,697 - 70,481,629 (-)NCBIHuRef
CHM1_19100,978,008 - 101,027,918 (-)NCBICHM1_1
T2T-CHM13v2.09110,207,739 - 110,291,169 (-)NCBIT2T-CHM13v2.0
Trim14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39446,505,072 - 46,536,148 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl446,493,781 - 46,536,141 (-)EnsemblGRCm39 Ensembl
GRCm38446,505,072 - 46,536,150 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl446,493,781 - 46,536,141 (-)EnsemblGRCm38mm10GRCm38
MGSCv37446,519,719 - 46,549,016 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36446,527,947 - 46,566,186 (-)NCBIMGSCv36mm8
Celera446,532,071 - 46,554,775 (-)NCBICelera
Cytogenetic Map4B1NCBI
cM Map424.84NCBI
Trim14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541927,390,173 - 27,419,681 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541927,390,098 - 27,420,727 (+)NCBIChiLan1.0ChiLan1.0
TRIM14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21141,338,703 - 41,420,016 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1941,341,080 - 41,422,385 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0969,176,088 - 69,209,574 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1997,294,407 - 97,330,059 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl997,294,407 - 97,330,059 (-)Ensemblpanpan1.1panPan2
TRIM14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11155,313,700 - 55,343,217 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1155,316,111 - 55,343,287 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1153,747,227 - 53,776,694 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01156,425,718 - 56,455,169 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1156,425,718 - 56,455,188 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11154,921,547 - 54,950,953 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01154,952,228 - 54,981,609 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01155,648,636 - 55,681,877 (-)NCBIUU_Cfam_GSD_1.0
Trim14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947170,245,978 - 170,269,447 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365246,797,762 - 6,816,607 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365246,797,788 - 6,816,582 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRIM14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,912,126 - 239,945,073 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,912,126 - 239,945,082 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21268,085,336 - 268,115,179 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRIM14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11241,303,240 - 41,359,509 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1241,303,404 - 41,335,492 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603838,338,418 - 38,399,400 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trim14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248252,749,863 - 2,768,700 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248252,749,911 - 2,767,737 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Trim14
195 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:483
Count of miRNA genes:243
Interacting mature miRNAs:295
Transcripts:ENSRNOT00000066001
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316954Rf57Renal function QTL 570kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)55979352890450144Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61386Bp49Blood pressure QTL 4916.6cerebrum integrity trait (VT:0010549)brain infarction volume (CMO:0001013)56029343498603051Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat

Markers in Region
RH128997  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,825,726 - 60,825,908 (+)MAPPERmRatBN7.2
Rnor_6.0562,154,631 - 62,154,812NCBIRnor6.0
Rnor_5.0566,682,310 - 66,682,491UniSTSRnor5.0
RGSC_v3.4563,119,388 - 63,119,569UniSTSRGSC3.4
Celera559,387,308 - 59,387,489UniSTS
RH 3.4 Map5384.5UniSTS
Cytogenetic Map5q22UniSTS
RH137252  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2560,800,649 - 60,800,831 (+)MAPPERmRatBN7.2
Rnor_6.0562,129,559 - 62,129,740NCBIRnor6.0
Rnor_5.0566,657,118 - 66,657,299UniSTSRnor5.0
RGSC_v3.4563,093,250 - 63,093,431UniSTSRGSC3.4
Celera559,362,266 - 59,362,447UniSTS
RH 3.4 Map5382.3UniSTS
Cytogenetic Map5q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 23 23 4 23 7
Low 4 34 18 15 18 2 2 66 35 32 11 2
Below cutoff 39 6 9 8 2 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001399174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006238062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC097073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC166777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ613985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ619746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ623323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ627052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ732697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ741120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ754505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ760825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ766302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000066001   ⟹   ENSRNOP00000062845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl560,800,032 - 60,824,858 (-)Ensembl
Rnor_6.0 Ensembl562,128,941 - 62,153,762 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086962   ⟹   ENSRNOP00000072771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl560,805,523 - 60,824,824 (-)Ensembl
Rnor_6.0 Ensembl562,129,147 - 62,153,786 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107290   ⟹   ENSRNOP00000088241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl560,800,570 - 60,824,841 (-)Ensembl
RefSeq Acc Id: NM_001107934   ⟹   NP_001101404
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,596,149 - 65,620,434 (-)NCBI
mRatBN7.2560,800,568 - 60,824,858 (-)NCBI
Rnor_6.0562,128,941 - 62,153,762 (-)NCBI
Rnor_5.0566,656,500 - 66,681,459 (-)NCBI
RGSC_v3.4563,092,632 - 63,118,519 (-)RGD
Celera559,361,648 - 59,386,439 (-)RGD
Sequence:
RefSeq Acc Id: NM_001399174   ⟹   NP_001386103
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,596,149 - 65,620,426 (-)NCBI
mRatBN7.2560,800,568 - 60,824,850 (-)NCBI
RefSeq Acc Id: XM_006238061   ⟹   XP_006238123
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,596,149 - 65,620,147 (-)NCBI
mRatBN7.2560,800,568 - 60,824,571 (-)NCBI
Rnor_6.0562,129,477 - 62,153,520 (-)NCBI
Rnor_5.0566,656,500 - 66,681,459 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006238062   ⟹   XP_006238124
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,596,149 - 65,620,150 (-)NCBI
mRatBN7.2560,800,568 - 60,822,608 (-)NCBI
Rnor_6.0562,129,477 - 62,151,663 (-)NCBI
Rnor_5.0566,656,500 - 66,681,459 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039109868   ⟹   XP_038965796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,596,149 - 65,616,419 (-)NCBI
mRatBN7.2560,800,568 - 60,820,673 (-)NCBI
RefSeq Acc Id: XM_039109869   ⟹   XP_038965797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8565,596,149 - 65,608,526 (-)NCBI
mRatBN7.2560,800,568 - 60,812,950 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001101404   ⟸   NM_001107934
- Peptide Label: isoform 2
- UniProtKB: D3ZBI1 (UniProtKB/TrEMBL),   A6IJC4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238123   ⟸   XM_006238061
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006238124   ⟸   XM_006238062
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000062845   ⟸   ENSRNOT00000066001
RefSeq Acc Id: ENSRNOP00000072771   ⟸   ENSRNOT00000086962
RefSeq Acc Id: XP_038965796   ⟸   XM_039109868
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038965797   ⟸   XM_039109869
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000088241   ⟸   ENSRNOT00000107290
RefSeq Acc Id: NP_001386103   ⟸   NM_001399174
- Peptide Label: isoform 1
- UniProtKB: B2RYH2 (UniProtKB/TrEMBL)
Protein Domains
B box-type   B30.2/SPRY

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B2RYH2-F1-model_v2 AlphaFold B2RYH2 1-440 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693715
Promoter ID:EPDNEW_R4239
Type:multiple initiation site
Name:Trim14_1
Description:tripartite motif-containing 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0562,153,754 - 62,153,814EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311514 AgrOrtholog
BioCyc Gene G2FUF-41403 BioCyc
Ensembl Genes ENSRNOG00000008922 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066001 ENTREZGENE
  ENSRNOT00000066001.3 UniProtKB/TrEMBL
  ENSRNOT00000086962.2 UniProtKB/TrEMBL
  ENSRNOT00000107290 ENTREZGENE
  ENSRNOT00000107290.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.920 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7934596 IMAGE-MGC_LOAD
InterPro B30.2/SPRY_sf UniProtKB/TrEMBL
  B302 UniProtKB/TrEMBL
  Butyrophylin UniProtKB/TrEMBL
  ConA-like_dom UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY_PRY_TRIM14 UniProtKB/TrEMBL
  SPRY_rcpt UniProtKB/TrEMBL
  Znf_B-box UniProtKB/TrEMBL
KEGG Report rno:313236 UniProtKB/TrEMBL
MGC_CLONE MGC:188556 IMAGE-MGC_LOAD
NCBI Gene 313236 ENTREZGENE
PANTHER B BOX-TYPE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  B-BOX DOMAIN CONTAINING UniProtKB/TrEMBL
Pfam PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
  zf-B_box UniProtKB/TrEMBL
PhenoGen Trim14 PhenoGen
PRINTS BUTYPHLNCDUF UniProtKB/TrEMBL
PROSITE B302_SPRY UniProtKB/TrEMBL
  ZF_BBOX UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008922 RatGTEx
SMART BBOX UniProtKB/TrEMBL
  PRY UniProtKB/TrEMBL
  SPRY UniProtKB/TrEMBL
Superfamily-SCOP B-box zinc-binding domain UniProtKB/TrEMBL
  ConA_like_lec_gl UniProtKB/TrEMBL
UniProt A0A0G2K3T6_RAT UniProtKB/TrEMBL
  A6IJC4 ENTREZGENE, UniProtKB/TrEMBL
  B2RYH2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBI1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-05-01 Trim14  tripartite motif-containing 14  Trim14  tripartite motif protein 14   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Trim14  tripartite motif protein 14   Trim14_predicted  tripartite motif protein 14 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Trim14_predicted  tripartite motif protein 14 (predicted)    tripartite motif-containing 14 (predicted)  Name updated 1299863 APPROVED
2005-01-12 Trim14_predicted  tripartite motif-containing 14 (predicted)      Symbol and Name status set to approved 70820 APPROVED