Trim14 (tripartite motif containing 14)

Gene: Trim14 (tripartite motif containing 14) Ictidomys tridecemlineatus

Analyze

Symbol:

Trim14

Name:

tripartite motif containing 14

RGD ID:

12733180

Description:

ENCODES a protein that exhibits molecular adaptor activity (inferred); transcription coactivator activity (inferred); zinc ion binding (inferred); INVOLVED IN inflammatory response (inferred); innate immune response (inferred); negative regulation of viral transcription (inferred); ASSOCIATED WITH congenital disorder of glycosylation Ii (ortholog); congenital disorder of glycosylation type II (ortholog); congenital myasthenic syndrome 14 (ortholog); FOUND IN cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tripartite motif-containing protein 14

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	170,245,978 - 170,269,447 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	6,797,762 - 6,816,607 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	6,797,788 - 6,816,582 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital disorder of glycosylation Ii (ISO)

congenital disorder of glycosylation type II (ISO)

congenital myasthenic syndrome 14 (ISO)

Generalized Epilepsy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

nephronophthisis (ISO)

spondyloepimetaphyseal dysplasia, Genevieve-type (ISO)

thoracic aortic aneurysm (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

inflammatory response (IEA)

innate immune response (IEA)

negative regulation of viral transcription (IEA)

positive regulation of DNA-templated transcription (IEA)

Cellular Component

cytoplasm (IEA,ISO)

Molecular Function

molecular adaptor activity (IEA)

protein binding (ISO)

transcription coactivator activity (IEA)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Trim14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	170,245,978 - 170,269,447 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	6,797,762 - 6,816,607 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	6,797,788 - 6,816,582 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIM14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	98,035,797 - 98,119,222 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	98,069,275 - 98,119,222 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	100,846,635 - 100,881,504 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	99,871,384 - 99,921,309 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	9	71,345,840 - 71,395,772 (-)	NCBI		Celera
Cytogenetic Map	9	q22.33	NCBI
HuRef	9	70,431,697 - 70,481,629 (-)	NCBI		HuRef
CHM1_1	9	100,978,008 - 101,027,918 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	110,207,739 - 110,291,169 (-)	NCBI		T2T-CHM13v2.0

Trim14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	46,505,072 - 46,536,148 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	46,493,781 - 46,536,141 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	46,505,072 - 46,536,150 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	46,493,781 - 46,536,141 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	46,519,719 - 46,549,016 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	46,527,947 - 46,566,186 (-)	NCBI		MGSCv36	mm8
Celera	4	46,532,071 - 46,554,775 (-)	NCBI		Celera
Cytogenetic Map	4	B1	NCBI
cM Map	4	24.84	NCBI

Trim14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	65,596,149 - 65,620,434 (-)	NCBI		GRCr8
mRatBN7.2	5	60,800,568 - 60,824,858 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	60,800,032 - 60,824,858 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	62,771,575 - 62,795,820 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	64,590,946 - 64,615,185 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	64,560,355 - 64,584,600 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	62,128,941 - 62,154,424 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	62,128,941 - 62,153,786 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	66,656,500 - 66,681,459 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	63,092,632 - 63,118,519 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	63,095,090 - 63,119,006 (-)	NCBI
Celera	5	59,361,648 - 59,386,439 (-)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

Trim14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	27,390,173 - 27,419,681 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	27,390,098 - 27,420,727 (+)	NCBI	ChiLan1.0	ChiLan1.0

TRIM14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	41,338,703 - 41,420,016 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	41,341,080 - 41,422,385 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	69,176,088 - 69,209,574 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	97,294,407 - 97,330,059 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	97,294,407 - 97,330,059 (-)	Ensembl	panpan1.1		panPan2

TRIM14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	55,313,700 - 55,343,217 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	55,316,111 - 55,343,287 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	53,747,227 - 53,776,694 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	56,425,718 - 56,455,169 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	56,425,718 - 56,455,188 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	54,921,547 - 54,950,953 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	54,952,228 - 54,981,609 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	55,648,636 - 55,681,877 (-)	NCBI		UU_Cfam_GSD_1.0

TRIM14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	239,912,126 - 239,945,073 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	239,912,126 - 239,945,082 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	268,085,336 - 268,115,179 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TRIM14
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	41,303,240 - 41,359,509 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	41,303,404 - 41,335,492 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	38,338,418 - 38,399,400 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Trim14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624825	2,749,863 - 2,768,700 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624825	2,749,911 - 2,767,737 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005326310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040286084	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040286085	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000020922 ⟹ ENSSTOP00000014964

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936524	6,797,762 - 6,816,607 (-)	Ensembl

RefSeq Acc Id:

XM_005326310 ⟹ XP_005326367

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	170,245,978 - 170,269,447 (-)	NCBI
SpeTri2.0	NW_004936524	6,797,788 - 6,816,582 (-)	NCBI

Sequence:

show sequence

ATGGAGGGCGCTGGGGCGCGGAGCACGACCCCCGGGGGGATCGGCTGTGCCGAGCCCGAGGAGG
CGCGCGGCTGGCTTTGCTCGGAACATAGCGACCGCCCTGCGGAGCTCTTCTGTCGCCGCTGCCG
CCGATGCGTGTGCGCGCTGTGCCCCGTGCTGGGCGCGCACCGCGGCCACCCGGTGGGCCTGGCG
CTGGAGGAGGCGGCCCACGTGCAGAAACTCATCCAAGAATGTTTACAGCAACTGGAGACCAAGA
AGCAGCATCAAGTTGGCAACATCACCCAGATAGAAGATGCAGCCGAGAAGCTCAAGGTTCACGC
AGAGTCAAGTAAAACCTGGCTGATGGACAAATTCACTGAACTCAGATTACTACTTGATGAAGAG
GAAATGCTGGCCAAAAAATTCATTGATAAAAACCTGCAGGGGGCCCTCCAGGTGTACAGGGAGC
AAGTGGAGTCTTGCAGGAAGCAGATTGACGTCATGGGCAGTCTCTCCAGCAGGGTCTGGGGTAT
CAGCCAGGAGCCCAACCCTGTTCAACTGCTGCAGGCCTACACAGCCACTGAGCAGGAGATGAAG
CAGCACATGAGCCTCGGGGAGCTGAGCCACCCCGTGCCCCTGTCCTTCGAGCCCATCAAGAGTC
TCTTTAAGGGCCTTGCGGAAGCCATGCAGAGTACGTTTCAGACACCACTAGACGTTCGCCTGAA
GGAAAACATCAACTGCCAGCTCTCAGGCTCCTCCAGCACCACACTTGGGACCCTGCTGAAAACA
AGCCCCTCACCAGAGAGATCGCTCTTCTTAAAATACGCGCGCACGCCCACGCTGGATCCGGACA
CGATGCACGCGCGCCTGCGCCTCTCCGCCGACGGCCTGACGGTGCGCAGCAGCCTGCTGGGCCG
CCTGGGGCCGATTCCCGCGAGGCGCTTCGACGCGCTGTGGCAGGTGCTGGGTCGCGACTGCTTC
GCCGCCGGCCGCCACTACTGGGAAGTGGACCTGCAGGAGGCGGGCTCCGGCTGGTGGGTGGGCG
CCGCCTACCCCTCCCTGCGGCGCCGCGGGGCCTCGGCCGCTGCCCGCCTGGGCTGCAACCGCCA
GTCCTGGTGCCTCAAGCGCTTCGACTTGGAATACTGGGCCTTCCACGATTGCCAGCGCAGTCGC
CTGAGGCCCCGCGATGACCCCGACCGGCTGGGCGTCTTCCTGGACTACGAGGCCGGCGTCCTCG
CCTTCTACGACGTGACGGGCGGCATGAGCCACCTGCACACCTTCCGCGCGGTCTTCCAGGAGCC
GCTGTACCCGGCCCTGCGGCTCTGGGAAGGGGCCATCAGCATCCCCCGGCTTCCCTAGGGACCC
ACCGGGCAGTGAGCCCCAGGCGCGCTTGTCCCTGGCGTGACTGGTTTGCTTTCTAAGACCTTCT
CCCGGGTCCAGCGCTCCCCCACCAGTGGGTTGTTTTGAACCTCTTCCCGGGCTAGTTTCAAACG
TGTCCCCAACACTGCTGCTGCCCTTTCCCCCACCACCATGGCTTCCGCTACACTACTTTCAGTG
CAGGTTTCTGAAGGGGACGTACCCGTACCCACAGGTGAGCTTCAGCATTCTGGCTTTGTCAGTG
CAGTTGTGCTCAGCCAGAGAACCGTCTTCATACGGCGCCTAGACCCTCCTGGCACATAGTAAGC
ACACAGTAAATACCAGCCTGCGAGTCGCACAGCGGTGGCTCTTCTATTCCTTAAGTTTCTGTGA
TCTGTCTGCTCTCCACCTACTTCAGCTTGTCCACGTCACCTCCCTTCAGAGCAACTGCAAGGGC
TTTTTACTTCCTGGTCTGAACCCTCTCTCATTTTCATCTTCTAAACCTAAAACTAGAGGGATCT
GTCTAGAACTCCCAAGAACTACAAAAATGAAAAACAAAACTCACCTTCCCTTAGCATTCAAGGC
TTTTCTAGTCTGCCCTCCTCGGCTTAGCCTCATGCAGGTCCTGTTGCTTTTTTCAAAGAGGCTC
CAGTCGGAACTGTCAGTTCTGCCTCTG

hide sequence

RefSeq Acc Id:

XM_040286084 ⟹ XP_040142018

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	170,245,978 - 170,268,687 (-)	NCBI

RefSeq Acc Id:

XM_040286085 ⟹ XP_040142019

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404947	170,245,978 - 170,268,912 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005326367	(Get FASTA)	NCBI Sequence Viewer
	XP_040142018	(Get FASTA)	NCBI Sequence Viewer
	XP_040142019	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000014964.1
GenBank Protein	KAG3287581	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005326367 ⟸ XM_005326310
- Peptide Label:	isoform X1
- UniProtKB:	I3MS69 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEGAGARSTTPGGIGCAEPEEARGWLCSEHSDRPAELFCRRCRRCVCALCPVLGAHRGHPVGLA LEEAAHVQKLIQECLQQLETKKQHQVGNITQIEDAAEKLKVHAESSKTWLMDKFTELRLLLDEE EMLAKKFIDKNLQGALQVYREQVESCRKQIDVMGSLSSRVWGISQEPNPVQLLQAYTATEQEMK QHMSLGELSHPVPLSFEPIKSLFKGLAEAMQSTFQTPLDVRLKENINCQLSGSSSTTLGTLLKT SPSPERSLFLKYARTPTLDPDTMHARLRLSADGLTVRSSLLGRLGPIPARRFDALWQVLGRDCF AAGRHYWEVDLQEAGSGWWVGAAYPSLRRRGASAAARLGCNRQSWCLKRFDLEYWAFHDCQRSR LRPRDDPDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAVFQEPLYPALRLWEGAISIPRLP hide sequence

RefSeq Acc Id:	XP_040142019 ⟸ XM_040286085
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_040142018 ⟸ XM_040286084
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSSTOP00000014964 ⟸ ENSSTOT00000020922

Protein Domains

B box-type B30.2/SPRY

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000027856	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000020922.2	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.920	UniProtKB/TrEMBL
	Classic Zinc Finger	UniProtKB/TrEMBL
InterPro	B30.2/SPRY	UniProtKB/TrEMBL
	B30.2/SPRY_sf	UniProtKB/TrEMBL
	Butyrophylin_SPRY	UniProtKB/TrEMBL
	ConA-like_dom_sf	UniProtKB/TrEMBL
	PRY	UniProtKB/TrEMBL
	SPRY_dom	UniProtKB/TrEMBL
	SPRY_PRY_TRIM14	UniProtKB/TrEMBL
	Znf_B-box	UniProtKB/TrEMBL
NCBI Gene	Trim14	ENTREZGENE
PANTHER	B BOX-TYPE DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
	B-BOX DOMAIN CONTAINING	UniProtKB/TrEMBL
Pfam	PRY	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
	zf-B_box	UniProtKB/TrEMBL
PRINTS	BUTYPHLNCDUF	UniProtKB/TrEMBL
PROSITE	B302_SPRY	UniProtKB/TrEMBL
	ZF_BBOX	UniProtKB/TrEMBL
SMART	BBOX	UniProtKB/TrEMBL
	PRY	UniProtKB/TrEMBL
	SPRY	UniProtKB/TrEMBL
Superfamily-SCOP	B-box zinc-binding domain	UniProtKB/TrEMBL
	SSF49899	UniProtKB/TrEMBL
UniProt	I3MS69	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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