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Gene: Cd226 (CD226 molecule) Rattus norvegicus

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Symbol:

Cd226

Name:

CD226 molecule

RGD ID:

1311513

Description:

Predicted to enable several functions, including identical protein binding activity; integrin binding activity; and protein kinase binding activity. Predicted to be involved in positive regulation of immune response and positive regulation of mast cell activation. Predicted to act upstream of or within natural killer cell mediated cytotoxicity; positive regulation of natural killer cell cytokine production; and positive regulation of type II interferon production. Predicted to be located in cell surface. Predicted to be active in external side of plasma membrane. Orthologous to human CD226 (CD226 molecule); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CD226 antigen; LOC307199

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CD226 (CD226 molecule)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Cd226 (CD226 antigen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cd226 (CD226 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CD226 (CD226 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CD226 (CD226 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CD226 (CD226 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CD226 (CD226 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cd226 (CD226 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Cd226 (CD226 molecule)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CD226 (CD226 molecule)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cd226 (CD226 antigen)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cd226 (CD226 molecule)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	cd226 (CD226 molecule)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	XB5717875 [provisional:plac8]	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	LOC105947528	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Cd226^{Tn(sb-T2/Bart3)2.141Mcwi}

Genetic Models:

F344-Cd226^{Tn(sb-T2/Bart3)2.141Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	84,723,330 - 84,819,836 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	84,725,242 - 84,819,835 (+)	Ensembl				GRCr8
mRatBN7.2	18	82,449,924 - 82,545,107 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	82,450,568 - 82,543,051 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	84,505,997 - 84,598,578 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	85,179,224 - 85,271,795 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	83,053,202 - 83,147,001 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	86,299,392 - 86,394,772 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	86,299,463 - 86,394,765 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	85,337,942 - 85,433,295 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	86,064,574 - 86,157,909 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	81,000,246 - 81,093,141 (+)	NCBI		Celera
RGSC_v3.1	18	86,157,214 - 86,230,246 (+)	NCBI
Cytogenetic Map	18	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chronic Hepatitis C (ISO)

Colorectal Neoplasms (ISO)

endometriosis (ISO)

Spontaneous Abortions (ISO)

systemic lupus erythematosus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

alpha-Zearalanol (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

clothianidin (ISO)

D-glucose (ISO)

disodium selenite (ISO)

folic acid (ISO)

fonofos (ISO)

fructose (ISO)

genistein (ISO)

glucose (ISO)

GSK-J4 (ISO)

mercury atom (ISO)

mercury(0) (ISO)

nickel atom (ISO)

nitrates (ISO)

parathion (ISO)

phenformin (EXP)

pirinixic acid (ISO)

progesterone (ISO)

Ptaquiloside (ISO)

rotenone (EXP)

silicon dioxide (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

terbufos (ISO)

testosterone (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

natural killer cell mediated cytotoxicity (IEA,ISO)

positive regulation of Fc receptor mediated stimulatory signaling pathway (IBA,IEA,ISO)

positive regulation of immunoglobulin mediated immune response (IBA,IEA,ISO)

positive regulation of mast cell activation (IEA,ISO)

positive regulation of natural killer cell cytokine production (IEA,ISO)

positive regulation of natural killer cell mediated cytotoxicity (IEA,ISO)

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target (IEA,ISO)

positive regulation of T cell receptor signaling pathway (IBA,IEA,ISO)

positive regulation of type II interferon production (ISO)

Cellular Component

cell surface (IEA,ISO)

external side of plasma membrane (IBA,IEA,ISO)

plasma membrane (IEA,ISO)

Molecular Function

cell adhesion molecule binding (IBA,IEA,ISO)

identical protein binding (IEA,ISO)

integrin binding (IEA,ISO)

protein binding (ISO)

protein kinase binding (IEA,ISO)

signaling receptor activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:12913096	PMID:15752754	PMID:16304049	PMID:16831868	PMID:19648922	PMID:22728856	PMID:24658051	PMID:26755705

Genomics

Comparative Map Data

Cd226
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	84,723,330 - 84,819,836 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	18	84,725,242 - 84,819,835 (+)	Ensembl				GRCr8
mRatBN7.2	18	82,449,924 - 82,545,107 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	82,450,568 - 82,543,051 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	18	84,505,997 - 84,598,578 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	85,179,224 - 85,271,795 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	83,053,202 - 83,147,001 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	86,299,392 - 86,394,772 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	86,299,463 - 86,394,765 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	18	85,337,942 - 85,433,295 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	18	86,064,574 - 86,157,909 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	18	81,000,246 - 81,093,141 (+)	NCBI		Celera
RGSC_v3.1	18	86,157,214 - 86,230,246 (+)	NCBI
Cytogenetic Map	18	q13	NCBI

CD226
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	69,853,274 - 69,961,773 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	69,831,158 - 69,961,803 (-)	Ensembl			hg38	GRCh38
GRCh37	18	67,520,510 - 67,624,035 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	65,681,172 - 65,775,139 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	18	65,681,174 - 65,775,140	NCBI
Celera	18	64,377,737 - 64,472,107 (-)	NCBI		Celera
Cytogenetic Map	18	q22.2	NCBI
HuRef	18	64,248,832 - 64,343,180 (-)	NCBI		HuRef
CHM1_1	18	67,525,491 - 67,619,446 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	18	70,070,086 - 70,220,680 (-)	NCBI		T2T-CHM13v2.0

Cd226
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	89,195,078 - 89,290,356 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	89,195,091 - 89,290,353 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	18	89,176,954 - 89,272,232 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	89,176,967 - 89,272,229 (+)	Ensembl			mm10	GRCm38
MGSCv37	18	89,366,819 - 89,439,719 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	18	89,331,620 - 89,404,520 (+)	NCBI		MGSCv36	mm8
Celera	18	90,925,452 - 90,998,347 (+)	NCBI		Celera
Cytogenetic Map	18	E4	NCBI
cM Map	18	59.05	NCBI

Cd226
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	53,473,131 - 53,560,924 (-)	Ensembl
ChiLan1.0	NW_004955402	53,408,861 - 53,560,896 (-)	NCBI	ChiLan1.0	ChiLan1.0

CD226
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	87,392,451 - 87,488,644 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	73,072,672 - 73,178,859 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	63,238,477 - 63,379,346 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	66,533,949 - 66,627,580 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	66,533,949 - 66,627,580 (-)	Ensembl			panPan2	panpan1.1

CD226
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	8,348,628 - 8,437,520 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	8,351,207 - 8,435,145 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	9,360,824 - 9,448,915 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	8,180,313 - 8,268,617 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	8,180,904 - 8,267,414 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	8,201,794 - 8,289,667 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	8,162,053 - 8,249,918 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	8,372,145 - 8,460,491 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

CD226
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	152,882,762 - 152,979,845 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	152,872,878 - 152,977,162 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	169,304,334 - 169,418,889 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CD226
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	9,790,483 - 9,900,376 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	9,811,168 - 9,901,830 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666060	15,904,002 - 16,007,951 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cd226
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624806	11,324,344 - 11,388,206 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624806	11,324,239 - 11,390,487 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cd226
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	15	43,493,000 - 43,567,253 (-)	NCBI		Rrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	131
Count of miRNA genes:	91
Interacting mature miRNAs:	115
Transcripts:	ENSRNOT00000058152
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303584	Gluco55	Glucose level QTL 55	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	18	50795212	86134022	Rat
9589041	Epfw12	Epididymal fat weight QTL 12	17.08	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	18	48915737	86134022	Rat
8694432	Bw165	Body weight QTL 165	3.81	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	48915737	86134022	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	65846447	86134022	Rat
1331730	Scl27	Serum cholesterol level QTL 27	3.826		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	18	54490801	86134022	Rat
1598832	Glom11	Glomerulus QTL 11	2.9		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	53266671	86134022	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	23494057	85487725	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19553532	85493247	Rat
1331770	Bp234	Blood pressure QTL 234	3.807		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	45620306	86134022	Rat
2303571	Bw92	Body weight QTL 92	3		body mass (VT:0001259)	body weight (CMO:0000012)	18	50795212	86134022	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31610505	85493247	Rat
738008	Hcar14	Hepatocarcinoma resistance QTL 14	4.3		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion number (CMO:0001462)	18	57825243	85493247	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	12066482	85493247	Rat
724542	Kidm2	Kidney mass QTL 2	2.6		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	18	61446853	86134022	Rat
61367	Iddm4	Insulin dependent diabetes mellitus QTL 4	2.33	0.0074	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	40462383	85462383	Rat
6893683	Bw110	Body weight QTL 110	2.7	0.002	body mass (VT:0001259)	body weight (CMO:0000012)	18	45620306	86134022	Rat
8694366	Abfw8	Abdominal fat weight QTL 8	6.38	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	18	48915737	86134022	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	12066482	85493247	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	15642280	86134022	Rat
7794793	Mcs34	Mammary carcinoma susceptibility QTL 34	1.54		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	18	65635567	85897775	Rat

Genetic Models

This gene Cd226 is modified in the following models/strains:

F344-Cd226^{Tn(sb-T2/Bart3)2.141Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	9	63	151	91	90	59	92	59	6	347	185	11	126	79	91	31	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001443518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001443519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600934	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600935	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600936	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017600941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096758	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277286	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000058152 ⟹ ENSRNOP00000054956

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	84,725,242 - 84,819,834 (+)	Ensembl
mRatBN7.2 Ensembl	18	82,450,568 - 82,543,051 (+)	Ensembl
Rnor_6.0 Ensembl	18	86,299,463 - 86,392,713 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091778 ⟹ ENSRNOP00000073108

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	18	86,307,646 - 86,394,765 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000172632 ⟹ ENSRNOP00000111825

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	18	84,725,332 - 84,819,835 (+)	Ensembl

RefSeq Acc Id:

NM_001107370 ⟹ NP_001100840

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	84,725,316 - 84,817,780 (+)	NCBI
mRatBN7.2	18	82,450,568 - 82,543,051 (+)	NCBI
Rnor_6.0	18	86,299,463 - 86,392,713 (+)	NCBI
Rnor_5.0	18	85,337,942 - 85,433,295 (+)	NCBI
RGSC_v3.4	18	86,064,574 - 86,157,909 (+)	RGD
Celera	18	81,000,246 - 81,093,141 (+)	RGD

Sequence:

show sequence

ATTTGCCTAGGTCTTGCACTTGTATTCCTGTAATGTACTTGCAAGAATACATTTCCTAGAAACC
TTAAGAGCATCACCACAACAACGGTGAAGAAAAGAAGGAGAAGGAAAGGGCAGTGGCGAAGGCA
GCATGGACACAGAGACCTAGGCCCTGGGCAATGTGGAAGGCAGTCCAACCTCCTGAACCGTTTC
CAGAGATGGCTTATCTTACTTGGCTTTTGGCTATTCTTCATGTGCACAAAGCGCTGTGTGAAGA
GACATTGTGGGACACAACTGTTCGTCTTTCTGAGACTATGACTTTGGAATGTGTATATCCATTG
ACGGATAACTTAACCCAGGCGGAGTGGACCAAGGACACTGGCACAAAGAAAGTGAACATAGCTG
TTTACCACCCTAACCATAATATGCATATAGATCCTAACTACCTCCATAGAGTGCACTTTCAAAA
TGCAACAGTGGGGTTCCGCAACATGAGCCTTTCCTTTTACAATGCCTCTGAAGCAGACATCGGC
ATCTACACCTGCTTGTTTCATGCTTTCCCACGTGGATCTTGGGAAAAGAAGATAAAAGTTGTCC
AGTCAGATAGTTTTGAGACAACAGCACCCTTGGATAGCTACCTGTCTGCAGAACCTGGACAAAA
TGTCACACTCAGTTGCCAGCTTGAAAGGACTTGGCTAGTGCAACTAGTCATATGGGAAAAAGTC
CAGCCCCATCAGGTAGACATCTTAGCTTCCTGTAACCTATCTCAAGGGACAAGATACACTTCAA
AGTACCTAAGACAAACATGGAGCGACTGTAGCCAGGAGAGCATGAAGAGTGCTCTCATTATACC
CTATGCCATGGCTGCTGACTCAGGACTTTACAGATGCCGCTCTGAGGCCAGTACGGGAACAAAC
AAAACCTGTGTCATAAGGCTGATCATAACTGATGGTGGAACCAATAACCACTTTATCCTTCTCA
TTGTCGGAGGGCTAGCCTCACTGCTACTTGTCATCCTAATTACCATCATTATTATCTTATTCAA
CAGGAAGAGAAGGAGACAGGTGAGAACTCCGCTTAAAGAGCTCAGAGATAAACAGAGTAAGGTA
GCCACCAACTGCAGAAGTCCAACTTCTCCCATTCAGACTACAGATGATGAAAAAGAGGACATTT
ATGTTAACTATCCAACTTTCTCTCGGAGACCAAAACCAAGATTCTAAGCCGCTCTTTTGCCTGA
GCACATTAGTAATGACTTCTATGGCATGGATTTTTACCCATGTCCTCCTCACCACCAGGATCTA
CATTGATTAAAAAGTTGATTGGATTTGTTTTATCTCATATATAGAAGTACTTTATGACCTGGGA
ATATTCTTAACAGAGATGGATTTGAAAACCCAAATCTAATTAACCGTTCAAGGAACAGTTCAAG
GAACCATCTTCCATTATATAACAGAGTAATCTAGAGAGGACTAAGTACCACGTGGCTTTCTTGC
TCTACTTGAAATCAGCTGTGAACATAAGTTTATTTCTGGATGCTTCCTACAGTGTTGGTTCTGC
TTATATACTACTGGTCCAACTCTCGTACTGCTTCTCTCAGATGCTCCCATGAGTATTGCCAAGG
ACACTTGGTAGAAAGTTTACTGGTTAAACACAGGAAACAAAGTTTATTATTCACTCACTAGCAA
GAAGGTAGCATTACCACAAAAGATTAGATGACCTAAATTAGCTGTGGGTTCAAGACCAGGACAA
AAGGGTTACTTGGGAATTCTGAGTATTGCTAAAAAGGCTGAAAGGGACCTAGAAGTTGAGTTAT
TTTTAACAAACTTTAACTTCAAAGGCATTGCTTATTAACTAGATAACAAATGAATGTACTGTAG
TATCAGCATAATTCAAAAGAATACATGCCAAGGAATGCCGAGAGCAGAGATAATTGTGTAACTA
TTTCTTCCCTTTCTGGTTTCAAATAAATTCATTTCTAATTCTATAGAGAAGTCTTGCTACCCAT
TCAGGACTGGTCTTCTATACAGTGAGATGGTCCAATTAGAAATAATTCTTTTAATAATGCTTTT
TCTACTTTCGAGAGTTATTTTAATATGTAAACTTGTGAGTTTAAAATCTTCAAAATGAGCACAT
GAAAAGAGATTGATGGTTTTAAGTAGTAGAATACAGTAATGTAGGAATCTGAGAGCAGAGAGTT
TGGGAGGGGGTGAAGAGGAAAAGACATCACCAAATAATGATATATGAGAGAAAATCTACACTTC
AGAGTTTGATCAAGGCCATATCTCCCAATTTGGCTGGCACTGAGATAATGCACCTGATGTCTCC
ATTTTAGA

hide sequence

RefSeq Acc Id:

XM_006255028 ⟹ XP_006255090

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	84,723,330 - 84,819,836 (+)	NCBI
mRatBN7.2	18	82,449,958 - 82,545,107 (+)	NCBI
Rnor_6.0	18	86,299,395 - 86,394,772 (+)	NCBI
Rnor_5.0	18	85,337,942 - 85,433,295 (+)	NCBI

Sequence:

show sequence

CAGTACAGATGAAGCTGACTGCTCTTTCCTGTTTGTTTCTCAGCAAACTATCCCAAAGAATCCT
CAGCATTTGCCTAGGTCTTGCACTTGTATTCCTGTAATGTACTTGCAAGAATACATTTCCTAGA
AACCTTAAGAGCATCACCACAACAACGGTGAAGAAAAGAAGGAGAAGGAAAGGGCAGTGGCGAA
GGCAGCATGGACACAGAGACCTAGGCCCTGGGCAATGTGGAAGGCAGGTACCAACCACCTTCAG
CATCATGTCAATCTCTTCTTAATAAAACGGCATGGGATTTTATTTTTAAATTGCATTTTTGTAT
ATTCTTGTTGCACAGAGCTGAGTCTGGCACAGAGGACACACTCAGTAAACATTTGTCAAATAAA
AGAATCTTTCTTGAAATTTGTATCTTTTGAAGTAAACTGATTATTCGACAGAGAAATAACTGCA
GCCTATCCATTCCTGTACGATAGCAAACCTTCCTTTGAAGCTGAAACTTCTTTCCTGTGCTCAT
ACTTCAGAGAAAAAGAAGAAGCTGATAACATCTGAGAGGAAGGAAATAGCTCTTCATGCTGAGT
TGTGAATATAACATCACACACACATTTTTTTTTAAACAGTCCAACCTCCTGAACCGTTTCCAGA
GATGGCTTATCTTACTTGGCTTTTGGCTATTCTTCATGTGCACAAAGCGCTGTGTGAAGAGACA
TTGTGGGACACAACTGTTCGTCTTTCTGAGACTATGACTTTGGAATGTGTATATCCATTGACGG
ATAACTTAACCCAGGCGGAGTGGACCAAGGACACTGGCACAAAGAAAGTGAACATAGCTGTTTA
CCACCCTAACCATAATATGCATATAGATCCTAACTACCTCCATAGAGTGCACTTTCAAAATGCA
ACAGTGGGGTTCCGCAACATGAGCCTTTCCTTTTACAATGCCTCTGAAGCAGACATCGGCATCT
ACACCTGCTTGTTTCATGCTTTCCCACGTGGATCTTGGGAAAAGAAGATAAAAGTTGTCCAGTC
AGATAGTTTTGAGACAACAGCACCCTTGGATAGCTACCTGTCTGCAGAACCTGGACAAAATGTC
ACACTCAGTTGCCAGCTTGAAAGGACTTGGCTAGTGCAACTAGTCATATGGGAAAAAGTCCAGC
CCCATCAGGTAGACATCTTAGCTTCCTGTAACCTATCTCAAGGGACAAGATACACTTCAAAGTA
CCTAAGACAAACATGGAGCGACTGTAGCCAGGAGAGCATGAAGAGTGCTCTCATTATACCCTAT
GCCATGGCTGCTGACTCAGGACTTTACAGATGCCGCTCTGAGGCCAGTACGGGAACAAACAAAA
CCTGTGTCATAAGGCTGATCATAACTGATGGTGGAACCAATAACCACTTTATCCTTCTCATTGT
CGGAGGGCTAGCCTCACTGCTACTTGTCATCCTAATTACCATCATTATTATCTTATTCAACAGG
AAGAGAAGGAGACAGGTGAGAACTCCGCTTAAAGAGCTCAGAGATAAACAGAGTAAGGTAGCCA
CCAACTGCAGAAGTCCAACTTCTCCCATTCAGACTACAGATGATGAAAAAGAGGACATTTATGT
TAACTATCCAACTTTCTCTCGGAGACCAAAACCAAGATTCTAAGCCGCTCTTTTGCCTGAGCAC
ATTAGTAATGACTTCTATGGCATGGATTTTTACCCATGTCCTCCTCACCACCAGGATCTACATT
GATTAAAAAGTTGATTGGATTTGTTTTATCTCATATATAGAAGTACTTTATGACCTGGGAATAT
TCTTAACAGAGATGGATTTGAAAACCCAAATCTAATTAACCGTTCAAGGAACAGTTCAAGGAAC
CATCTTCCATTATATAACAGAGTAATCTAGAGAGGACTAAGTACCACGTGGCTTTCTTGCTCTA
CTTGAAATCAGCTGTGAACATAAGTTTATTTCTGGATGCTTCCTACAGTGTTGGTTCTGCTTAT
ATACTACTGGTCCAACTCTCGTACTGCTTCTCTCAGATGCTCCCATGAGTATTGCCAAGGACAC
TTGGTAGAAAGTTTACTGGTTAAACACAGGAAACAAAGTTTATTATTCACTCACTAGCAAGAAG
GTAGCATTACCACAAAAGATTAGATGACCTAAATTAGCTGTGGGTTCAAGACCAGGACAAAAGG
GTTACTTGGGAATTCTGAGTATTGCTAAAAAGGCTGAAAGGGACCTAGAAGTTGAGTTATTTTT
AACAAACTTTAACTTCAAAGGCATTGCTTATTAACTAGATAACAAATGAATGTACTGTAGTATC
AGCATAATTCAAAAGAATACATGCCAAGGAATGCCGAGAGCAGAGATAATTGTGTAACTATTTC
TTCCCTTTCTGGTTTCAAATAAATTCATTTCTAATTCTATAGAGAAGTCTTGCTACCCATTCAG
GACTGGTCTTCTATACAGTGAGATGGTCCAATTAGAAATAATTCTTTTAATAATGCTTTTTCTA
CTTTCGAGAGTTATTTTAATATGTAAACTTGTGAGTTTAAAATCTTCAAAATGAGCACATGAAA
AGAGATTGATGGTTTTAAGTAGTAGAATACAGTAATGTAGGAATCTGAGAGCAGAGAGTTTGGG
AGGGGGTGAAGAGGAAAAGACATCACCAAATAATGATATATGAGAGAAAATCTACACTTCAGAG
TTTGATCAAGGCCATATCTCCCAATTTGGCTGGCACTGAGATAATGCACCTGATGTCTCCATTT
TAGAAAAAAAATGAGTATTTGTGGAATTAAATAAAACTCTAGTTATCTCAAAACTATGGTAATC
ATTATCAAATAGAATGATATTTAGTATCTAAAAGACCCATTTCTTATCTGTAAAAAATTTAAAT
GATCATAATCTTTAAATATTCATTGTGGAAAACTTCGATTAAGTTTGTGGTGTGAAAATTTTGT
TACAAACTTAAGTGAAAACAATCCAAATGCTAATGCGGTTACATAGATTCTAAAATGCAATTCA
TAGTTTTAAGATAATTAGTAGATACTTCATATTTTAACCTTAGATACCATGCATGATAAATAGG
CCAATTATTTTCCCAATTACAGAAATTCAGAAGGTAATAAACGAAAATGACAGTTTCTTAGTTG
TGCTTATATATTTACTCAAGAATAGCTAATTAACTCAGATTTTGACTGATTGCTTGAAAATTTT
TGTGTCTCAATTTGTGAACTGTTTCTCTAAATATGCCAGTGTACCATTGTTGAAATACAATTAA
CCAGAAAATAGTCAACATTTGGAACCATAGGAGATCACAACACAGTTTGCATGGTTAAACAACT
TAGTGTTGTTCATAAAATAAACTAATTATTCTTCCATAAATGTTAAAGACAATCAAAATACTAC
TTTCTATCATGTTTGGAAGCCAAGTTTTGCAATGGCTAAGTTGGTGAGAGGGAAAGCTTTTATA
ATGGCATTATAGGGAGATAGCTACCTGGTAGTCCGTGATTTGTATGAAGAGTCACCTAAGTAGA
TCAAGAAAGCCTCCAGATCACTGGACACTCTTCTTTGTTTCTGTGGAGATTCATATGCTGTTTC
GAAAAAAAAAATCACTCTGTCAAAATATATTTTCTCTGCCTACCCTTCCTTTCTATATGTAGTT
CCCTTACAGAATTTAGTATTTATTGGGAATACTTACTACCACCTTGACCTCCCTATGTCTCTGT
TATGCTGCAGAGACAATGTTCATTGACTCTGTAGACATTTTTATTAAAGAAAGCACTTTAATTG
CAATCTTTGTGGCCTATACAATTCACAAGAATTCTGTAATGTGACCCCTCCAAAAATTTTTGTG
CCTATTGTTCTGATTGGTAGCAGAGCAATCAAAACTGCACCAAAATAAAAGATGAATGTCAGAA
ATGAAATACAATTTTGTTCTCCATGTTTTATTTTATTTTTTAATATTTAGTGCTGCTTTGGAAG
TCAGATGCTTTCTGGAGGTGCTTTACTCAGATAATGGATACCAGTATATAATGCAATGTTTAAG
TGAAATATGTATGCTTGAATTAAATGCTATAATCTTAATATTTACATTAAAGTAAACAAAGAAA
GGTTTGATTAGGAATAGAGCAGTTTCTTAGGTGCTTACAATAACTGTGTATATACTATGTTATT
ATCAGACTGGTGTCGTTTCATTTAAAAGCATTTGTTAATATTGAGAAAATAGAAAATATATCTT
TATTGTTCTCTTTTATTCTTTCCTATATTTCTCTTACTGAAAATTGAATTCAAGGCTTTTAAAT
ATCAGGCAAGTGCTATGCTTCTGAGATACACTCTAGTTCACCATATAGTTTAAAGTTTAAATAT
TCAACTAATTGTCAAGATACTATCATTAAATATAAATTTAAAAAGATAAAGTAAAACCTAGGAG
GTTCTTTTTTATTTTAAACATGCAAGTTTTATTAGTTTACATATAGAACTCTATTAGATGAAAT
GATATAATTATAATTATCTTTTAAATTAGGAAACCCCACACTATAGTTAGAGATCAGTTTACAT
AGTTTAATTTTTTATGTTCAAAGCAATAACACTGTTGTAAGATGCTGGTAGAAAATGCTTTATT
TGAGGATATGGATAATAATTGTCTGGTTCTGATTAGTTGCTTATTGTTTCTGTTGTAATTATAA
GTTCTATGACAATTGTATTTTGAGCATTGTTTCCAGTTTTATTTTCCATTATCAGAGACTGAAT
TTGTAGGCATAAAGCAGCTCTTATCCCTCAATGTACTATAATCTATTGTTCTCAATGAATAAAA
CATAGTTCTCAATGA

hide sequence

RefSeq Acc Id:

XM_006255031 ⟹ XP_006255093

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	84,723,330 - 84,819,836 (+)	NCBI
mRatBN7.2	18	82,449,958 - 82,545,107 (+)	NCBI
Rnor_6.0	18	86,299,395 - 86,394,772 (+)	NCBI
Rnor_5.0	18	85,337,942 - 85,433,295 (+)	NCBI

Sequence:

show sequence

CAGTACAGATGAAGCTGACTGCTCTTTCCTGTTTGTTTCTCAGCAAACTATCCCAAAGAATCCT
CAGCATTTGCCTAGGTCTTGCACTTGTATTCCTGTAATGTACTTGCAAGAATACATTTCCTAGA
AACCTTAAGAGCATCACCACAACAACGGTGAAGAAAAGAAGGAGAAGGAAAGGGCAGTGGCGAA
GGCAGCATGGACACAGAGACCTAGGCCCTGGGCAATGTGGAAGGCAGAGAAAAAGAAGAAGCTG
ATAACATCTGAGAGGAAGGAAATAGCTCTTCATGCTGAGTTGTGAATATAACATCACACACACA
TTTTTTTTTAAACAGTCCAACCTCCTGAACCGTTTCCAGAGATGGCTTATCTTACTTGGCTTTT
GGCTATTCTTCATGTGCACAAAGCGCTGTGTGAAGAGACATTGTGGGACACAACTGTTCGTCTT
TCTGAGACTATGACTTTGGAATGTGTATATCCATTGACGGATAACTTAACCCAGGCGGAGTGGA
CCAAGGACACTGGCACAAAGAAAGTGAACATAGCTGTTTACCACCCTAACCATAATATGCATAT
AGATCCTAACTACCTCCATAGAGTGCACTTTCAAAATGCAACAGTGGGGTTCCGCAACATGAGC
CTTTCCTTTTACAATGCCTCTGAAGCAGACATCGGCATCTACACCTGCTTGTTTCATGCTTTCC
CACGTGGATCTTGGGAAAAGAAGATAAAAGTTGTCCAGTCAGATAGTTTTGAGACAACAGCACC
CTTGGATAGCTACCTGTCTGCAGAACCTGGACAAAATGTCACACTCAGTTGCCAGCTTGAAAGG
ACTTGGCTAGTGCAACTAGTCATATGGGAAAAAGTCCAGCCCCATCAGGTAGACATCTTAGCTT
CCTGTAACCTATCTCAAGGGACAAGATACACTTCAAAGTACCTAAGACAAACATGGAGCGACTG
TAGCCAGGAGAGCATGAAGAGTGCTCTCATTATACCCTATGCCATGGCTGCTGACTCAGGACTT
TACAGATGCCGCTCTGAGGCCAGTACGGGAACAAACAAAACCTGTGTCATAAGGCTGATCATAA
CTGATGGTGGAACCAATAACCACTTTATCCTTCTCATTGTCGGAGGGCTAGCCTCACTGCTACT
TGTCATCCTAATTACCATCATTATTATCTTATTCAACAGGAAGAGAAGGAGACAGGTGAGAACT
CCGCTTAAAGAGCTCAGAGATAAACAGAGTAAGGTAGCCACCAACTGCAGAAGTCCAACTTCTC
CCATTCAGACTACAGATGATGAAAAAGAGGACATTTATGTTAACTATCCAACTTTCTCTCGGAG
ACCAAAACCAAGATTCTAAGCCGCTCTTTTGCCTGAGCACATTAGTAATGACTTCTATGGCATG
GATTTTTACCCATGTCCTCCTCACCACCAGGATCTACATTGATTAAAAAGTTGATTGGATTTGT
TTTATCTCATATATAGAAGTACTTTATGACCTGGGAATATTCTTAACAGAGATGGATTTGAAAA
CCCAAATCTAATTAACCGTTCAAGGAACAGTTCAAGGAACCATCTTCCATTATATAACAGAGTA
ATCTAGAGAGGACTAAGTACCACGTGGCTTTCTTGCTCTACTTGAAATCAGCTGTGAACATAAG
TTTATTTCTGGATGCTTCCTACAGTGTTGGTTCTGCTTATATACTACTGGTCCAACTCTCGTAC
TGCTTCTCTCAGATGCTCCCATGAGTATTGCCAAGGACACTTGGTAGAAAGTTTACTGGTTAAA
CACAGGAAACAAAGTTTATTATTCACTCACTAGCAAGAAGGTAGCATTACCACAAAAGATTAGA
TGACCTAAATTAGCTGTGGGTTCAAGACCAGGACAAAAGGGTTACTTGGGAATTCTGAGTATTG
CTAAAAAGGCTGAAAGGGACCTAGAAGTTGAGTTATTTTTAACAAACTTTAACTTCAAAGGCAT
TGCTTATTAACTAGATAACAAATGAATGTACTGTAGTATCAGCATAATTCAAAAGAATACATGC
CAAGGAATGCCGAGAGCAGAGATAATTGTGTAACTATTTCTTCCCTTTCTGGTTTCAAATAAAT
TCATTTCTAATTCTATAGAGAAGTCTTGCTACCCATTCAGGACTGGTCTTCTATACAGTGAGAT
GGTCCAATTAGAAATAATTCTTTTAATAATGCTTTTTCTACTTTCGAGAGTTATTTTAATATGT
AAACTTGTGAGTTTAAAATCTTCAAAATGAGCACATGAAAAGAGATTGATGGTTTTAAGTAGTA
GAATACAGTAATGTAGGAATCTGAGAGCAGAGAGTTTGGGAGGGGGTGAAGAGGAAAAGACATC
ACCAAATAATGATATATGAGAGAAAATCTACACTTCAGAGTTTGATCAAGGCCATATCTCCCAA
TTTGGCTGGCACTGAGATAATGCACCTGATGTCTCCATTTTAGAAAAAAAATGAGTATTTGTGG
AATTAAATAAAACTCTAGTTATCTCAAAACTATGGTAATCATTATCAAATAGAATGATATTTAG
TATCTAAAAGACCCATTTCTTATCTGTAAAAAATTTAAATGATCATAATCTTTAAATATTCATT
GTGGAAAACTTCGATTAAGTTTGTGGTGTGAAAATTTTGTTACAAACTTAAGTGAAAACAATCC
AAATGCTAATGCGGTTACATAGATTCTAAAATGCAATTCATAGTTTTAAGATAATTAGTAGATA
CTTCATATTTTAACCTTAGATACCATGCATGATAAATAGGCCAATTATTTTCCCAATTACAGAA
ATTCAGAAGGTAATAAACGAAAATGACAGTTTCTTAGTTGTGCTTATATATTTACTCAAGAATA
GCTAATTAACTCAGATTTTGACTGATTGCTTGAAAATTTTTGTGTCTCAATTTGTGAACTGTTT
CTCTAAATATGCCAGTGTACCATTGTTGAAATACAATTAACCAGAAAATAGTCAACATTTGGAA
CCATAGGAGATCACAACACAGTTTGCATGGTTAAACAACTTAGTGTTGTTCATAAAATAAACTA
ATTATTCTTCCATAAATGTTAAAGACAATCAAAATACTACTTTCTATCATGTTTGGAAGCCAAG
TTTTGCAATGGCTAAGTTGGTGAGAGGGAAAGCTTTTATAATGGCATTATAGGGAGATAGCTAC
CTGGTAGTCCGTGATTTGTATGAAGAGTCACCTAAGTAGATCAAGAAAGCCTCCAGATCACTGG
ACACTCTTCTTTGTTTCTGTGGAGATTCATATGCTGTTTCGAAAAAAAAAATCACTCTGTCAAA
ATATATTTTCTCTGCCTACCCTTCCTTTCTATATGTAGTTCCCTTACAGAATTTAGTATTTATT
GGGAATACTTACTACCACCTTGACCTCCCTATGTCTCTGTTATGCTGCAGAGACAATGTTCATT
GACTCTGTAGACATTTTTATTAAAGAAAGCACTTTAATTGCAATCTTTGTGGCCTATACAATTC
ACAAGAATTCTGTAATGTGACCCCTCCAAAAATTTTTGTGCCTATTGTTCTGATTGGTAGCAGA
GCAATCAAAACTGCACCAAAATAAAAGATGAATGTCAGAAATGAAATACAATTTTGTTCTCCAT
GTTTTATTTTATTTTTTAATATTTAGTGCTGCTTTGGAAGTCAGATGCTTTCTGGAGGTGCTTT
ACTCAGATAATGGATACCAGTATATAATGCAATGTTTAAGTGAAATATGTATGCTTGAATTAAA
TGCTATAATCTTAATATTTACATTAAAGTAAACAAAGAAAGGTTTGATTAGGAATAGAGCAGTT
TCTTAGGTGCTTACAATAACTGTGTATATACTATGTTATTATCAGACTGGTGTCGTTTCATTTA
AAAGCATTTGTTAATATTGAGAAAATAGAAAATATATCTTTATTGTTCTCTTTTATTCTTTCCT
ATATTTCTCTTACTGAAAATTGAATTCAAGGCTTTTAAATATCAGGCAAGTGCTATGCTTCTGA
GATACACTCTAGTTCACCATATAGTTTAAAGTTTAAATATTCAACTAATTGTCAAGATACTATC
ATTAAATATAAATTTAAAAAGATAAAGTAAAACCTAGGAGGTTCTTTTTTATTTTAAACATGCA
AGTTTTATTAGTTTACATATAGAACTCTATTAGATGAAATGATATAATTATAATTATCTTTTAA
ATTAGGAAACCCCACACTATAGTTAGAGATCAGTTTACATAGTTTAATTTTTTATGTTCAAAGC
AATAACACTGTTGTAAGATGCTGGTAGAAAATGCTTTATTTGAGGATATGGATAATAATTGTCT
GGTTCTGATTAGTTGCTTATTGTTTCTGTTGTAATTATAAGTTCTATGACAATTGTATTTTGAG
CATTGTTTCCAGTTTTATTTTCCATTATCAGAGACTGAATTTGTAGGCATAAAGCAGCTCTTAT
CCCTCAATGTACTATAATCTATTGTTCTCAATGAATAAAACATAGTTCTCAATGA

hide sequence

RefSeq Acc Id:

XM_039096758 ⟹ XP_038952686

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	84,731,649 - 84,819,836 (+)	NCBI
mRatBN7.2	18	82,456,291 - 82,545,107 (+)	NCBI

RefSeq Acc Id:

XM_039096759 ⟹ XP_038952687

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	84,723,330 - 84,819,836 (+)	NCBI
mRatBN7.2	18	82,449,958 - 82,545,107 (+)	NCBI

RefSeq Acc Id:

XM_063277286 ⟹ XP_063133356

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	84,731,649 - 84,819,836 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100840	(Get FASTA)	NCBI Sequence Viewer
	NP_001430447	(Get FASTA)	NCBI Sequence Viewer
	NP_001430448	(Get FASTA)	NCBI Sequence Viewer
	XP_006255090	(Get FASTA)	NCBI Sequence Viewer
	XP_006255093	(Get FASTA)	NCBI Sequence Viewer
	XP_038952686	(Get FASTA)	NCBI Sequence Viewer
	XP_038952687	(Get FASTA)	NCBI Sequence Viewer
	XP_063133356	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL75159	(Get FASTA)	NCBI Sequence Viewer
	EDL75160	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000054956
	ENSRNOP00000054956.2
	ENSRNOP00000111825
	ENSRNOP00000111825.1

RefSeq Acc Id:	NP_001100840 ⟸ NM_001107370
- Peptide Label:	precursor
- UniProtKB:	D3ZS97 (UniProtKB/TrEMBL), A6K5P0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWKAVQPPEPFPEMAYLTWLLAILHVHKALCEETLWDTTVRLSETMTLECVYPLTDNLTQAEWT KDTGTKKVNIAVYHPNHNMHIDPNYLHRVHFQNATVGFRNMSLSFYNASEADIGIYTCLFHAFP RGSWEKKIKVVQSDSFETTAPLDSYLSAEPGQNVTLSCQLERTWLVQLVIWEKVQPHQVDILAS CNLSQGTRYTSKYLRQTWSDCSQESMKSALIIPYAMAADSGLYRCRSEASTGTNKTCVIRLIIT DGGTNNHFILLIVGGLASLLLVILITIIIILFNRKRRRQVRTPLKELRDKQSKVATNCRSPTSP IQTTDDEKEDIYVNYPTFSRRPKPRF hide sequence

RefSeq Acc Id:	XP_006255090 ⟸ XM_006255028
- Peptide Label:	isoform X1
- UniProtKB:	A6K5P1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAYLTWLLAILHVHKALCEETLWDTTVRLSETMTLECVYPLTDNLTQAEWTKDTGTKKVNIAVY HPNHNMHIDPNYLHRVHFQNATVGFRNMSLSFYNASEADIGIYTCLFHAFPRGSWEKKIKVVQS DSFETTAPLDSYLSAEPGQNVTLSCQLERTWLVQLVIWEKVQPHQVDILASCNLSQGTRYTSKY LRQTWSDCSQESMKSALIIPYAMAADSGLYRCRSEASTGTNKTCVIRLIITDGGTNNHFILLIV GGLASLLLVILITIIIILFNRKRRRQVRTPLKELRDKQSKVATNCRSPTSPIQTTDDEKEDIYV NYPTFSRRPKPRF hide sequence

RefSeq Acc Id:	XP_006255093 ⟸ XM_006255031
- Peptide Label:	isoform X1
- UniProtKB:	A6K5P1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAYLTWLLAILHVHKALCEETLWDTTVRLSETMTLECVYPLTDNLTQAEWTKDTGTKKVNIAVY HPNHNMHIDPNYLHRVHFQNATVGFRNMSLSFYNASEADIGIYTCLFHAFPRGSWEKKIKVVQS DSFETTAPLDSYLSAEPGQNVTLSCQLERTWLVQLVIWEKVQPHQVDILASCNLSQGTRYTSKY LRQTWSDCSQESMKSALIIPYAMAADSGLYRCRSEASTGTNKTCVIRLIITDGGTNNHFILLIV GGLASLLLVILITIIIILFNRKRRRQVRTPLKELRDKQSKVATNCRSPTSPIQTTDDEKEDIYV NYPTFSRRPKPRF hide sequence

Ensembl Acc Id:

ENSRNOP00000054956 ⟸ ENSRNOT00000058152

Ensembl Acc Id:

ENSRNOP00000073108 ⟸ ENSRNOT00000091778

RefSeq Acc Id:	XP_038952687 ⟸ XM_039096759
- Peptide Label:	isoform X1
- UniProtKB:	A6K5P1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038952686 ⟸ XM_039096758
- Peptide Label:	isoform X1
- UniProtKB:	A6K5P1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063133356 ⟸ XM_063277286
- Peptide Label:	isoform X1
- UniProtKB:	A6K5P1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000111825 ⟸ ENSRNOT00000172632

Protein Domains

Ig-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZS97-F1-model_v2	AlphaFold	D3ZS97	1-346	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700909

Promoter ID:

EPDNEW_R11422

Type:

single initiation site

Name:

Cd226_1

Description:

CD226 molecule

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	86,307,693 - 86,307,753	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311513	AgrOrtholog
BioCyc Gene	G2FUF-6690	BioCyc
Ensembl Genes	ENSRNOG00000038197	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000058152	ENTREZGENE
	ENSRNOT00000058152.5	UniProtKB/TrEMBL
	ENSRNOT00000172632	ENTREZGENE
	ENSRNOT00000172632.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	CD226	UniProtKB/TrEMBL
	Ig-like	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/TrEMBL
KEGG Report	rno:307199	UniProtKB/TrEMBL
NCBI Gene	307199	ENTREZGENE
PANTHER	CD226 ANTIGEN	UniProtKB/TrEMBL
	PTHR47011	UniProtKB/TrEMBL
Pfam	V-set	UniProtKB/TrEMBL
PhenoGen	Cd226	PhenoGen
PROSITE	IG_LIKE	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000038197	RatGTEx
SMART	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0ABK0M175_RAT	UniProtKB/TrEMBL
	A6K5P0	ENTREZGENE, UniProtKB/TrEMBL
	A6K5P1	ENTREZGENE, UniProtKB/TrEMBL
	D3ZS97	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-18	Cd226	CD226 antigen	Cd226_predicted	CD226 antigen (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Cd226_predicted	CD226 antigen (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD