Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gfod1 | Rat | (+)-catechin | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of GFOD1 mRNA | CTD | PMID:24763279 | Gfod1 | Rat | 15-acetyldeoxynivalenol | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | 15-acetyldeoxynivalenol results in increased expression of GFOD1 mRNA | CTD | PMID:23792671 | Gfod1 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of GFOD1 mRNA | CTD | PMID:29097150 | Gfod1 | Rat | 17beta-estradiol | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of GFOD1 mRNA | CTD | PMID:30165855 | Gfod1 | Rat | 17beta-estradiol | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of GFOD1 mRNA | CTD | PMID:31614463 | Gfod1 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Gfod1 | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Gfod1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GFOD1 mRNA | CTD | PMID:19933214 | Gfod1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GFOD1 mRNA | CTD | PMID:33387578 and PMID:34747641 | Gfod1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Gfod1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of GFOD1 mRNA | CTD | PMID:21570461 | Gfod1 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Gfod1 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of GFOD1 mRNA | CTD | PMID:28628672 | Gfod1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Gfod1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of GFOD1 mRNA | CTD | PMID:30951980 | Gfod1 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Gfod1 (Mus musculus) | 6480464 | bisphenol S affects the methylation of GFOD1 gene | CTD | PMID:31683443 | Gfod1 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | GFOD1 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of GFOD1 gene | CTD | PMID:31601247 | Gfod1 | Rat | acrolein | decreases expression | EXP | | 6480464 | Acrolein results in decreased expression of GFOD1 mRNA | CTD | PMID:38090360 | Gfod1 | Rat | aflatoxin B1 | increases methylation | ISO | GFOD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of GFOD1 gene more ... | CTD | PMID:27153756 and PMID:30157460 | Gfod1 | Rat | Aflatoxin B2 alpha | increases methylation | ISO | GFOD1 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of GFOD1 intron | CTD | PMID:30157460 | Gfod1 | Rat | all-trans-retinoic acid | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of GFOD1 mRNA | CTD | PMID:33167477 | Gfod1 | Rat | amiodarone | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of GFOD1 mRNA | CTD | PMID:19774075 | Gfod1 | Rat | antimycin A | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Antimycin A results in increased expression of GFOD1 mRNA | CTD | PMID:33512557 | Gfod1 | Rat | arsane | affects methylation | ISO | GFOD1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GFOD1 gene | CTD | PMID:25304211 | Gfod1 | Rat | arsenic atom | affects methylation | ISO | GFOD1 (Homo sapiens) | 6480464 | Arsenic affects the methylation of GFOD1 gene | CTD | PMID:25304211 | Gfod1 | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of GFOD1 mRNA | CTD | PMID:36841081 | Gfod1 | Rat | benzo[a]pyrene | decreases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of GFOD1 mRNA | CTD | PMID:20064835 and PMID:22316170 | Gfod1 | Rat | benzo[a]pyrene | decreases methylation | ISO | GFOD1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of GFOD1 promoter | CTD | PMID:27901495 | Gfod1 | Rat | bis(2-chloroethyl) sulfide | decreases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Mustard Gas results in decreased expression of GFOD1 mRNA | CTD | PMID:12884408 | Gfod1 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of GFOD1 mRNA | CTD | PMID:31163220 | Gfod1 | Rat | bisphenol A | decreases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GFOD1 mRNA | CTD | PMID:20678512 | Gfod1 | Rat | bisphenol A | increases methylation | ISO | GFOD1 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of GFOD1 gene | CTD | PMID:31601247 | Gfod1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of GFOD1 gene | CTD | PMID:28505145 | Gfod1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GFOD1 mRNA | CTD | PMID:29097150 | Gfod1 | Rat | bisphenol A | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of GFOD1 mRNA | CTD | PMID:27685785 | Gfod1 | Rat | bisphenol F | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of GFOD1 mRNA | CTD | PMID:28628672 | Gfod1 | Rat | bisphenol F | increases expression | ISO | Gfod1 (Mus musculus) | 6480464 | bisphenol F results in increased expression of GFOD1 mRNA | CTD | PMID:38685157 | Gfod1 | Rat | cadmium dichloride | decreases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of GFOD1 mRNA | CTD | PMID:38568856 | Gfod1 | Rat | cannabidiol | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GFOD1 mRNA] | CTD | PMID:27256343 | Gfod1 | Rat | cantharidin | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Cantharidin results in decreased expression of GFOD1 mRNA | CTD | PMID:36907384 | Gfod1 | Rat | chloroprene | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Chloroprene results in decreased expression of GFOD1 mRNA | CTD | PMID:23125180 | Gfod1 | Rat | chlorpyrifos | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of GFOD1 mRNA | CTD | PMID:37019170 | Gfod1 | Rat | choline | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GFOD1 gene | CTD | PMID:20938992 | Gfod1 | Rat | cisplatin | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of GFOD1 mRNA | CTD | PMID:27392435 | Gfod1 | Rat | cisplatin | decreases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of GFOD1 mRNA | CTD | PMID:27392435 | Gfod1 | Rat | cyclosporin A | decreases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of GFOD1 mRNA | CTD | PMID:20106945 | Gfod1 | Rat | dexamethasone | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of GFOD1 mRNA | CTD | PMID:28628672 | Gfod1 | Rat | diethyl maleate | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | diethyl maleate results in increased expression of GFOD1 mRNA | CTD | PMID:33545341 | Gfod1 | Rat | dorsomorphin | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GFOD1 mRNA | CTD | PMID:27188386 | Gfod1 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of GFOD1 mRNA | CTD | PMID:29391264 | Gfod1 | Rat | ferroheme b | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Heme metabolite results in decreased expression of GFOD1 mRNA | CTD | PMID:19191707 | Gfod1 | Rat | fluoranthene | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of GFOD1 mRNA | CTD | PMID:28329830 | Gfod1 | Rat | folic acid | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GFOD1 gene | CTD | PMID:20938992 | Gfod1 | Rat | folpet | increases expression | ISO | Gfod1 (Mus musculus) | 6480464 | folpet results in increased expression of GFOD1 mRNA | CTD | PMID:31558096 | Gfod1 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of GFOD1 mRNA | CTD | PMID:33387578 | Gfod1 | Rat | heme b | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Heme metabolite results in decreased expression of GFOD1 mRNA | CTD | PMID:19191707 | Gfod1 | Rat | hydrogen cyanide | increases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Hydrogen Cyanide results in increased expression of GFOD1 mRNA | CTD | PMID:33914522 | Gfod1 | Rat | indometacin | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of GFOD1 mRNA | CTD | PMID:28628672 | Gfod1 | Rat | isoflurane | decreases methylation | ISO | Gfod1 (Mus musculus) | 6480464 | Isoflurane results in decreased methylation of GFOD1 mRNA | CTD | PMID:35249202 | Gfod1 | Rat | kojic acid | decreases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | kojic acid results in decreased expression of GFOD1 mRNA | CTD | PMID:16595896 | Gfod1 | Rat | L-methionine | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of GFOD1 gene | CTD | PMID:20938992 | Gfod1 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of GFOD1 gene | CTD | PMID:33148267 | Gfod1 | Rat | ozone | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of GFOD1 mRNA | CTD | PMID:34911549 | Gfod1 | Rat | paracetamol | affects expression | ISO | Gfod1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of GFOD1 mRNA | CTD | PMID:17562736 | Gfod1 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of GFOD1 mRNA | CTD | PMID:33387578 | Gfod1 | Rat | PCB138 | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Gfod1 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of GFOD1 mRNA | CTD | PMID:37995155 | Gfod1 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of GFOD1 gene | CTD | PMID:33148267 | Gfod1 | Rat | pirinixic acid | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of GFOD1 mRNA | CTD | PMID:20813756 | Gfod1 | Rat | potassium cyanide | increases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Potassium Cyanide results in increased expression of GFOD1 mRNA | CTD | PMID:33914522 | Gfod1 | Rat | propanal | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of GFOD1 mRNA | CTD | PMID:26079696 | Gfod1 | Rat | quercetin | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of GFOD1 mRNA | CTD | PMID:21632981 | Gfod1 | Rat | resveratrol | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of GFOD1 mRNA | CTD | PMID:23557933 | Gfod1 | Rat | rotenone | increases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Rotenone results in increased expression of GFOD1 mRNA | CTD | PMID:32937126 | Gfod1 | Rat | SB 431542 | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GFOD1 mRNA | CTD | PMID:27188386 | Gfod1 | Rat | silicon dioxide | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of GFOD1 mRNA | CTD | PMID:25895662 | Gfod1 | Rat | sodium arsenite | decreases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of GFOD1 mRNA | CTD | PMID:38568856 | Gfod1 | Rat | succimer | multiple interactions | ISO | Gfod1 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of GFOD1 mRNA | CTD | PMID:21641980 | Gfod1 | Rat | temozolomide | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of GFOD1 mRNA | CTD | PMID:31758290 | Gfod1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of GFOD1 mRNA | CTD | PMID:34492290 | Gfod1 | Rat | thiram | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Thiram results in increased expression of GFOD1 mRNA | CTD | PMID:38568856 | Gfod1 | Rat | titanium dioxide | increases methylation | ISO | Gfod1 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of GFOD1 gene | CTD | PMID:35295148 | Gfod1 | Rat | trichloroethene | decreases expression | ISO | Gfod1 (Mus musculus) | 6480464 | Trichloroethylene results in decreased expression of GFOD1 mRNA | CTD | PMID:28973375 | Gfod1 | Rat | triphenyl phosphate | affects expression | ISO | GFOD1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of GFOD1 mRNA | CTD | PMID:37042841 | Gfod1 | Rat | tunicamycin | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of GFOD1 mRNA | CTD | PMID:33545341 | Gfod1 | Rat | urethane | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Urethane results in increased expression of GFOD1 mRNA | CTD | PMID:28818685 | Gfod1 | Rat | valproic acid | affects expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of GFOD1 mRNA | CTD | PMID:25979313 | Gfod1 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of GFOD1 mRNA | CTD | PMID:29427782 | Gfod1 | Rat | valproic acid | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GFOD1 mRNA | CTD | PMID:22083351 more ... | Gfod1 | Rat | valproic acid | multiple interactions | ISO | GFOD1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GFOD1 mRNA | CTD | PMID:27188386 | Gfod1 | Rat | vitamin E | increases expression | ISO | GFOD1 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of GFOD1 mRNA | CTD | PMID:19244175 | |