Tent5a (terminal nucleotidyltransferase 5A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Tent5a (terminal nucleotidyltransferase 5A) Rattus norvegicus
Analyze
Symbol: Tent5a
Name: terminal nucleotidyltransferase 5A
RGD ID: 1311381
Description: Predicted to enable poly(A) RNA polymerase activity. Predicted to be involved in mRNA stabilization; positive regulation of bone mineralization; and positive regulation of osteoblast differentiation. Predicted to act upstream of or within response to bacterium. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma; osteoarthritis; and osteogenesis imperfecta type 18. Orthologous to human TENT5A (terminal nucleotidyltransferase 5A); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fam46a; family with sequence similarity 46, member A; hypothetical protein LOC300870; LOC300870; RGD1311381; similar to hypothetical protein FLJ20037; uncharacterized protein LOC300870
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8895,102,349 - 95,109,100 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl895,105,412 - 95,109,100 (-)EnsemblGRCr8
mRatBN7.2886,222,294 - 86,229,045 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl886,225,357 - 86,229,045 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx891,880,503 - 91,884,196 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0890,079,943 - 90,083,636 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0887,932,331 - 87,936,024 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0892,935,474 - 92,942,267 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl892,937,739 - 92,942,076 (-)Ensemblrn6Rnor6.0
Rnor_5.0892,448,628 - 92,455,379 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4890,502,441 - 90,506,129 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera885,847,174 - 85,850,862 (-)NCBICelera
RGSC_v3.1890,522,538 - 90,525,616 (-)NCBI
Cytogenetic Map8q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphotericin B  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
camptothecin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cytarabine  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diethyl maleate  (EXP)
dioxygen  (ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
etoposide  (ISO)
fipronil  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
GSK-J4  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
leflunomide  (EXP,ISO)
lidocaine  (EXP)
methamphetamine  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mitomycin C  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (EXP)
niclosamide  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
torcetrapib  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Susceptibility to large-joint osteoarthritis (hip and knee) is associated with BAG6 rs3117582 SNP and the VNTR polymorphism in the second exon of the FAM46A gene on chromosome 6. Etokebe GE, etal., J Orthop Res. 2015 Jan;33(1):56-62. doi: 10.1002/jor.22738. Epub 2014 Sep 18.
2. Association of the FAM46A gene VNTRs and BAG6 rs3117582 SNP with non small cell lung cancer (NSCLC) in Croatian and Norwegian populations. Etokebe GE, etal., PLoS One. 2015 Apr 17;10(4):e0122651. doi: 10.1371/journal.pone.0122651. eCollection 2015.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21810271   PMID:22658674   PMID:23012479  


Genomics

Comparative Map Data
Tent5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8895,102,349 - 95,109,100 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl895,105,412 - 95,109,100 (-)EnsemblGRCr8
mRatBN7.2886,222,294 - 86,229,045 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl886,225,357 - 86,229,045 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx891,880,503 - 91,884,196 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0890,079,943 - 90,083,636 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0887,932,331 - 87,936,024 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0892,935,474 - 92,942,267 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl892,937,739 - 92,942,076 (-)Ensemblrn6Rnor6.0
Rnor_5.0892,448,628 - 92,455,379 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4890,502,441 - 90,506,129 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera885,847,174 - 85,850,862 (-)NCBICelera
RGSC_v3.1890,522,538 - 90,525,616 (-)NCBI
Cytogenetic Map8q31NCBI
TENT5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38681,745,730 - 81,752,681 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl681,491,439 - 81,752,774 (-)Ensemblhg38GRCh38
GRCh37682,455,447 - 82,462,398 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36682,512,166 - 82,519,147 (-)NCBIBuild 36Build 36hg18NCBI36
Celera682,878,343 - 82,885,324 (-)NCBICelera
Cytogenetic Map6q14.1NCBI
HuRef679,672,933 - 79,679,910 (-)NCBIHuRef
CHM1_1682,553,088 - 82,560,049 (-)NCBICHM1_1
T2T-CHM13v2.0682,955,095 - 82,962,045 (-)NCBIT2T-CHM13v2.0
Tent5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39985,202,492 - 85,209,203 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl985,202,492 - 85,209,401 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38985,320,439 - 85,327,150 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl985,320,439 - 85,327,348 (-)Ensemblmm10GRCm38
MGSCv37985,214,046 - 85,220,757 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36985,117,157 - 85,124,012 (-)NCBIMGSCv36mm8
Celera982,403,616 - 82,410,396 (-)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map946.04NCBI
Tent5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554119,699,011 - 9,701,507 (-)Ensembl
ChiLan1.0NW_0049554119,695,149 - 9,701,463 (-)NCBIChiLan1.0ChiLan1.0
TENT5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25101,840,559 - 101,847,729 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1699,719,648 - 99,726,814 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0679,636,412 - 79,643,444 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1682,901,079 - 82,908,072 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl682,901,079 - 82,908,072 (-)EnsemblpanPan2panpan1.1
TENT5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11242,270,029 - 42,277,905 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1242,274,000 - 42,277,513 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1242,148,920 - 42,156,806 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01243,037,950 - 43,045,845 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1243,041,928 - 43,044,620 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11242,349,866 - 42,357,748 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01242,326,251 - 42,334,268 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01242,481,165 - 42,489,053 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tent5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494677,649,982 - 77,656,958 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365108,814,292 - 8,816,929 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365108,813,977 - 8,820,909 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TENT5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl184,545,202 - 84,552,134 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1184,545,033 - 84,552,138 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2195,104,279 - 95,111,386 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TENT5A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1136,392,131 - 6,399,456 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl136,392,025 - 6,398,564 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040182,632,569 - 182,640,200 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tent5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479912,829,528 - 12,834,511 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462479912,829,562 - 12,836,850 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tent5a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1879,385,102 - 79,391,901 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tent5a
28 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:353
Count of miRNA genes:200
Interacting mature miRNAs:237
Transcripts:ENSRNOT00000056937
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH127808  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2886,222,526 - 86,222,713 (+)MAPPERmRatBN7.2
Rnor_6.0892,935,707 - 92,935,893NCBIRnor6.0
Rnor_5.0892,448,861 - 92,449,047UniSTSRnor5.0
RGSC_v3.4890,499,611 - 90,499,797UniSTSRGSC3.4
Celera885,844,344 - 85,844,530UniSTS
RH 3.4 Map8984.4UniSTS
RH 3.4 Map8987.2UniSTS
Cytogenetic Map8q31UniSTS
RH134851  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2886,224,479 - 86,224,667 (+)MAPPERmRatBN7.2
Rnor_6.0892,937,660 - 92,937,847NCBIRnor6.0
Rnor_5.0892,450,814 - 92,451,001UniSTSRnor5.0
RGSC_v3.4890,501,564 - 90,501,751UniSTSRGSC3.4
Celera885,846,297 - 85,846,484UniSTS
RH 3.4 Map8988.6UniSTS
Cytogenetic Map8q31UniSTS
Fam46a  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2886,226,530 - 86,226,640 (+)MAPPERmRatBN7.2
Rnor_6.0892,939,711 - 92,939,820NCBIRnor6.0
Rnor_5.0892,452,865 - 92,452,974UniSTSRnor5.0
RGSC_v3.4890,503,615 - 90,503,724UniSTSRGSC3.4
Celera885,848,348 - 85,848,457UniSTS
Cytogenetic Map8q31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000056937   ⟹   ENSRNOP00000053775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl895,105,412 - 95,109,100 (-)Ensembl
mRatBN7.2 Ensembl886,225,357 - 86,229,045 (-)Ensembl
Rnor_6.0 Ensembl892,937,739 - 92,942,076 (-)Ensembl
RefSeq Acc Id: NM_001106844   ⟹   NP_001100314
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8895,105,412 - 95,109,100 (-)NCBI
mRatBN7.2886,225,357 - 86,229,045 (-)NCBI
Rnor_6.0892,938,537 - 92,942,225 (-)NCBI
Rnor_5.0892,448,628 - 92,455,379 (-)NCBI
RGSC_v3.4890,502,441 - 90,506,129 (-)RGD
Celera885,847,174 - 85,850,862 (-)RGD
Sequence:
RefSeq Acc Id: XM_006243474   ⟹   XP_006243536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8895,102,349 - 95,109,096 (-)NCBI
mRatBN7.2886,222,294 - 86,229,041 (-)NCBI
Rnor_6.0892,935,474 - 92,942,267 (-)NCBI
Rnor_5.0892,448,628 - 92,455,379 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001100314 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423404 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243536 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77647 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000053775
  ENSRNOP00000053775.2
RefSeq Acc Id: NP_001100314   ⟸   NM_001106844
- UniProtKB: D3ZH34 (UniProtKB/TrEMBL),   A6I1T0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243536   ⟸   XM_006243474
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000053775   ⟸   ENSRNOT00000056937

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZH34-F1-model_v2 AlphaFold D3ZH34 1-446 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311381 AgrOrtholog
BioCyc Gene G2FUF-29660 BioCyc
Ensembl Genes ENSRNOG00000010240 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000056937 ENTREZGENE
  ENSRNOT00000056937.5 UniProtKB/TrEMBL
InterPro DUF1693 UniProtKB/TrEMBL
KEGG Report rno:300870 UniProtKB/TrEMBL
NCBI Gene 300870 ENTREZGENE
PANTHER PTHR12974 UniProtKB/TrEMBL
  TERMINAL NUCLEOTIDYLTRANSFERASE 5A UniProtKB/TrEMBL
Pfam DUF1693 UniProtKB/TrEMBL
PhenoGen Tent5a PhenoGen
RatGTEx ENSRNOG00000010240 RatGTEx
SMART DUF1693 UniProtKB/TrEMBL
UniProt A6I1T0 ENTREZGENE, UniProtKB/TrEMBL
  D3ZH34 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-04-30 Tent5a  terminal nucleotidyltransferase 5A  Fam46a  family with sequence similarity 46, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Fam46a  family with sequence similarity 46, member A  RGD1311381_predicted  similar to hypothetical protein FLJ20037 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1311381_predicted  similar to hypothetical protein FLJ20037 (predicted)  LOC300870_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC300870_predicted  similar to hypothetical protein FLJ20037 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL