Advanced Search (OLGA)

Gene: Insc (INSC, spindle orientation adaptor protein) Rattus norvegicus

Analyze

Symbol:

Insc

Name:

INSC, spindle orientation adaptor protein

RGD ID:

1311379

Description:

Predicted to enable cytoskeletal anchor activity and protein domain specific binding activity. Predicted to be involved in apical protein localization; regulation of asymmetric cell division; and regulation of protein stability. Predicted to be located in cell cortex and plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in apical cortex. Orthologous to human INSC (INSC spindle orientation adaptor protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical LOC293166; inscuteable homolog; inscuteable homolog (Drosophila); LOC293166; RGD1311379

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	INSC (INSC spindle orientation adaptor protein)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Insc (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Insc (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	INSC (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	INSC (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Insc (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	INSC (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	INSC (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Insc (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Insc (INSC spindle orientation adaptor protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TNFAIP1 (TNF alpha induced protein 1)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Insc (INSC spindle orientation adaptor protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	INSC (INSC spindle orientation adaptor protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	insc-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	insc-1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	insc	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	insc	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	insc	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	insc	Alliance	DIOPT (OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	178,427,360 - 178,534,827 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	178,427,423 - 178,535,047 (+)	Ensembl				GRCr8
mRatBN7.2	1	168,993,032 - 169,100,438 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	168,993,032 - 169,100,433 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	177,313,540 - 177,420,920 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	184,499,609 - 184,606,997 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	177,206,376 - 177,313,740 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	184,299,200 - 184,407,487 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	184,299,250 - 184,407,480 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	191,272,625 - 191,380,862 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	172,804,412 - 172,913,667 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	166,826,157 - 166,933,448 (+)	NCBI		Celera
RGSC_v3.1	1	172,938,861 - 173,045,793 (+)	NCBI
Cytogenetic Map	1	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(2,4,5-trichlorophenoxy)acetic acid (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aldrin (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bromobenzene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

cantharidin (ISO)

carbon nanotube (ISO)

chenodeoxycholic acid (ISO)

chlorpyrifos (ISO)

clofibrate (ISO)

copper(II) chloride (ISO)

copper(II) sulfate (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

deoxycholic acid (ISO)

dexamethasone (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

fulvestrant (ISO)

furan (ISO)

genistein (ISO)

glycochenodeoxycholic acid (ISO)

glycocholic acid (ISO)

glycodeoxycholic acid (ISO)

mono(2-ethylhexyl) phthalate (ISO)

okadaic acid (ISO)

ozone (ISO)

panobinostat (ISO)

paracetamol (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

Sunset Yellow FCF (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

Triptolide (ISO)

triptonide (ISO)

troglitazone (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apical protein localization (IBA)

asymmetric cell division (IEA)

cell differentiation (IEA)

nervous system development (IEA)

regulation of asymmetric cell division (IBA)

regulation of protein stability (IEA,ISO)

Cellular Component

apical cortex (IBA)

cell cortex (IEA,ISO)

plasma membrane (IEA,ISO)

protein-containing complex (IEA,ISO)

Molecular Function

cytoskeletal anchor activity (IBA)

protein binding (ISO)

protein domain specific binding (IEA,ISO)

protein-macromolecule adaptor activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:16458856	PMID:22074847

Genomics

Comparative Map Data

Insc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	178,427,360 - 178,534,827 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	178,427,423 - 178,535,047 (+)	Ensembl				GRCr8
mRatBN7.2	1	168,993,032 - 169,100,438 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	168,993,032 - 169,100,433 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	177,313,540 - 177,420,920 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	184,499,609 - 184,606,997 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	177,206,376 - 177,313,740 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	184,299,200 - 184,407,487 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	184,299,250 - 184,407,480 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	191,272,625 - 191,380,862 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	172,804,412 - 172,913,667 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	166,826,157 - 166,933,448 (+)	NCBI		Celera
RGSC_v3.1	1	172,938,861 - 173,045,793 (+)	NCBI
Cytogenetic Map	1	q34	NCBI

INSC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	15,111,416 - 15,269,676 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	15,112,424 - 15,247,208 (+)	Ensembl			hg38	GRCh38
GRCh37	11	15,133,970 - 15,268,754 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	15,090,546 - 15,225,330 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	11	15,261,213 - 15,395,928 (+)	NCBI		Celera
Cytogenetic Map	11	p15.2	NCBI
HuRef	11	14,817,520 - 14,952,207 (+)	NCBI		HuRef
CHM1_1	11	15,132,981 - 15,268,351 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	15,207,776 - 15,366,083 (+)	NCBI		T2T-CHM13v2.0

Insc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	114,342,931 - 114,449,615 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	114,342,929 - 114,449,618 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	114,743,688 - 114,850,380 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	114,743,694 - 114,850,383 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	121,889,280 - 121,993,894 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	114,583,211 - 114,641,363 (+)	NCBI		MGSCv36	mm8
Celera	7	114,699,353 - 114,804,111 (+)	NCBI		Celera
Cytogenetic Map	7	F1	NCBI
cM Map	7	60.23	NCBI

Insc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	30,156,327 - 30,283,146 (+)	Ensembl
ChiLan1.0	NW_004955414	30,181,402 - 30,282,279 (+)	NCBI	ChiLan1.0	ChiLan1.0

INSC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	17,481,904 - 17,613,908 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	17,407,636 - 17,574,975 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	15,203,357 - 15,335,341 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	14,892,357 - 15,024,344 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	14,892,357 - 15,024,344 (+)	Ensembl			panPan2	panpan1.1

INSC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	37,942,334 - 38,063,690 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	37,942,294 - 38,063,146 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	37,447,110 - 37,565,970 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	39,072,642 - 39,160,340 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	39,039,305 - 39,160,039 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	38,058,728 - 38,177,862 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	38,263,829 - 38,382,671 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	38,551,635 - 38,670,419 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Insc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	47,528,402 - 47,647,823 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936528	3,562,854 - 3,681,669 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936528	3,562,426 - 3,681,733 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

INSC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	43,843,568 - 44,015,191 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	43,843,539 - 44,015,266 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	47,050,716 - 47,221,492 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

INSC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	49,674,580 - 49,807,746 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	49,675,737 - 49,807,208 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	147,170,322 - 147,302,423 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Insc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	6,884,824 - 7,016,392 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624766	6,935,814 - 7,016,335 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Insc
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	86,692,679 - 86,797,661 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Insc
933 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	41
Count of miRNA genes:	34
Interacting mature miRNAs:	40
Transcripts:	ENSRNOT00000030540
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	160111531	262090437	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	266453731	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	137611478	182611478	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	153679879	198679879	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	177339686	222339686	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	132760429	191848948	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	153679879	205813246	Rat
8694166	Bw147	Body weight QTL 147	6.83	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	1	153788989	198788989	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	176288899	270518180	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	142582336	182383862	Rat
1354636	Lmblg1	Limb length QTL 1	6.4		tibia length (VT:0004357)	tibia length (CMO:0000450)	1	160573753	210707719	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	162548015	270518180	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	152919152	268496042	Rat
1354634	Kidm12	Kidney mass QTL 12	3.9		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	1	160573753	210707719	Rat
4889428	Stresp24	Stress response QTL 24		0.05	heart pumping trait (VT:2000009)	absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)	1	165278545	210278545	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	160111531	262090437	Rat
61343	Bp28	Blood pressure QTL 28			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	161077990	206077990	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
61347	Bp197	Blood pressure QTL 197	4.2		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	1	168063662	213063662	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	159894717	207261263	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
2303622	Vencon6	Ventilatory control QTL 6		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	1	163992710	208992710	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	146080545	243492863	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	155359438	194575574	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	140833106	185833106	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	153679879	232414077	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	160574007	235238518	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	160111426	262090599	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	132760429	191848948	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	154961463	266453731	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	162753891	207753891	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	153680016	182383862	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	153680016	183564652	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	172718770	228180370	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
2312558	Glom17	Glomerulus QTL 17	3.9	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	175967553	200707874	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
1582204	Livw1	Liver weight QTL 1	3.6	0.0003	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	1	170078537	182384005	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	266453731	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1354620	Kidm19	Kidney mass QTL 19	4		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	160573753	210707719	Rat
1576310	Schws2	Schwannoma susceptibility QTL 2		0.029	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	1	153788989	198788989	Rat
1354618	Kidm15	Kidney mass QTL 15	5		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	1	165707719	210707719	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	173363824	227535316	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	180021436	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	191190115	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	132966869	206393015	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	140915717	185915717	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	132760429	191848948	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat
7411599	Foco11	Food consumption QTL 11	18.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	1	153788989	198788989	Rat
1354602	Bw35	Body weight QTL 35	12.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	160573753	210707719	Rat

Markers in Region

D9S290

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	1	191,375,224 - 191,375,503	NCBI	Rnor5.0
Rnor_5.0	4	37,850,046 - 37,850,387	NCBI	Rnor5.0
RGSC_v3.4	4	36,926,808 - 36,927,148	UniSTS	RGSC3.4
RGSC_v3.4	1	172,908,037 - 172,908,315	UniSTS	RGSC3.4
Celera	4	35,260,183 - 35,260,523	UniSTS
Celera	1	166,927,818 - 166,928,096	UniSTS
Cytogenetic Map	1	q34	UniSTS

RH137050

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	169,100,148 - 169,100,311 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	184,407,196 - 184,407,358	NCBI	Rnor6.0
Rnor_5.0	1	191,380,571 - 191,380,733	UniSTS	Rnor5.0
RGSC_v3.4	1	172,913,383 - 172,913,545	UniSTS	RGSC3.4
Celera	1	166,933,164 - 166,933,326	UniSTS
RH 3.4 Map	1	1316.9	UniSTS
Cytogenetic Map	1	q34	UniSTS

AU048457

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	169,019,462 - 169,019,683 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	184,325,679 - 184,325,899	NCBI	Rnor6.0
Rnor_5.0	1	191,299,054 - 191,299,274	UniSTS	Rnor5.0
RGSC_v3.4	1	172,830,842 - 172,831,062	UniSTS	RGSC3.4
Celera	1	166,852,593 - 166,852,813	UniSTS
Cytogenetic Map	1	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	53	141	90	89	59	24	59	6	244	110	11	120	51	92	30	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588970	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017588972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106440	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039106441	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285287	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285288	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030540 ⟹ ENSRNOP00000031361

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	178,427,423 - 178,534,822 (+)	Ensembl
mRatBN7.2 Ensembl	1	168,993,032 - 169,100,433 (+)	Ensembl
Rnor_6.0 Ensembl	1	184,299,250 - 184,407,480 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078096 ⟹ ENSRNOP00000074463

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	178,427,423 - 178,534,822 (+)	Ensembl
mRatBN7.2 Ensembl	1	168,993,032 - 169,099,585 (+)	Ensembl
Rnor_6.0 Ensembl	1	184,301,493 - 184,407,478 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107702 ⟹ ENSRNOP00000084803

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	178,432,393 - 178,531,840 (+)	Ensembl
mRatBN7.2 Ensembl	1	168,993,032 - 169,097,701 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000147302 ⟹ ENSRNOP00000101229

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	178,429,382 - 178,531,840 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000148497 ⟹ ENSRNOP00000101230

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	178,429,382 - 178,534,834 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000169476 ⟹ ENSRNOP00000102436

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	178,429,382 - 178,535,047 (+)	Ensembl

RefSeq Acc Id:

NM_001106285 ⟹ NP_001099755

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	178,427,423 - 178,534,822 (+)	NCBI
mRatBN7.2	1	168,993,032 - 169,100,433 (+)	NCBI
Rnor_6.0	1	184,299,250 - 184,407,480 (+)	NCBI
Rnor_5.0	1	191,272,625 - 191,380,862 (+)	NCBI
RGSC_v3.4	1	172,804,412 - 172,913,667 (+)	RGD
Celera	1	166,826,157 - 166,933,448 (+)	RGD

Sequence:

show sequence

GCAGCCTTAGTCCTGAGCAGCCTTGAGAGTCTGCCCATTGGCCTTTGCTTTGAATCTCAGGCCT
TCTCAGGTCCATGGCCCAGAAGGATGGGTGGAGAGAATGAAGCTGCTCACAGGGGCCTCCGTAA
GAACACCTAAATCACTATAGCCCAGACTGTGACCATGAGGCGGCCCCCAGGGGATGGAGACTCC
ACCGGAGAAGGCCCAGGAAACTGGGGCTTATGGGGAGCCCAGGAGTCCAGGAGGCTGTGCTGTG
TTGGGCCAGACCGCTGTGGGCAGGCACTACTGCAGATTGGAATGAACATGATGGCACTACCTGG
AGGCCGGCACCTGGGTTCCATTCCTCTGCAAGAGCAGAGGCTACACTTCATGCAGGTGGACTCG
GTTCAGCGCTGGATGGAGGATCTGAAGCTCATGACCGAGTGTGAGTGCATGTGCGTCTTGCAGG
CAAAGCCCATCAGCCTGGAGGAAGACACGCAGAGTGACCTTATCCTAGCAGGTGGTCCTGGACC
AGGAGATCCTCTGCAGCTGCTCCTGAAGCGGGGCTGGGTCATCAGCACAGAGCTTCGAAGGATC
GGGCAGAAGCTGGCCCAGGACCGCTGGGCACGCGTGCACAGCATGAGTGTGCGTCTGACGTGCC
ATGCACGTTCCATGGTCAGCGAGTACAGCACCATCAGCAGGACAACCTCGCAGGAAATGGGCCA
GGCAGAGAAGCTGCTCATGGAGAAATGCTCCGAGCTCTCTGCGGTCACTGAGAGGTGCCTCCAA
GTGGAAAATGAGCATGTTCTGAAGTCAATGAAGGCCTGCGTGAGTGAGACCCTGAGCATGTTGG
GCCAGCACTTTGGCCAGCTACTGGAACTGGCCCTCACACGGGAAGTGCAGGCACTTGTGAGAAA
AATCGATACCTCAGACAATATCTACATCACGGAATCTACCACAGGGAACCTCTTCAGCCTGACC
CAGGAGGGGGCTCCTTTGTGCCGCATCATAGCCAAGGAAGGTGGGGTTGTAGCCCTCTTCAAGG
TCTGCCGGCAGGACACCTTCCGGTGTTTGTACCCCCAGGCGCTCCGCACACTGGCCTCTATCTG
CTGTGTGGAAGAGGGTGTCCATCAGCTGGAAAAGGTGGATGGTATCCTGTGCTTGACGGACATC
TTGACTGATGATAGCCACTCAGAGGCCACTCGAGCTGAGGCTGCAGCCGTGGTAGCCCAGGTTA
CCTCTCCACATCTGTCTTTCACCCAGCACCTCACTAGCTTTCTGGAGAACATGGAGGAGATTGT
GACAGCCCTAATCAAACTGTGCCAAGAGGCCTCATCAGGGGAAGTCTTCCTGCTGGCTTCTGCG
GCCCTTGCCAATATCACCTTCTTCGAAAAAATGGCCTGTGAGATGCTTCTGCAGTTGAATGCAA
TCCGTGTCCTTCTGGAAGCCTGTGGTGACAAACAGAGAGTAGACACACCTTATACTCGGGACCA
GATTGTGACCATCTTGGCAAACATGTCTGTGCTGGAGCAGTGTGCCTCTGACATCATTCAGGAG
AATGGTGTCCAGCTCATCATGGGCATGCTGTCGGAGAAGCCAAGGTCTGGGACGCCTGCTGAAG
TGGCAGCCTGTGAGAGAGTACAGCAGAAAGCTGCAGTGACCCTGGCCCGCCTCTGCCGAGACCC
AGATGTGGCCCGGGAGGCTGTGCGGCTCAGCTGTATGTCTCGCCTGATTGAGCTCTGCAGATCC
CCCTCTGAGAGGAACAGCAGCGATGCCGTCCTGGTAGCCTGCCTGGCTGCCTTGCGTCGCTTGG
CTGGGGTCTGCCCCGAAGGCCTTCAGGACTCTGACTTCCAGCAGCTGGTCCAGCCTCGGCTTGT
GGATTCCTTCTTGCTGTGTAGCAATATGGAGGAGAGTTTTGTTTAGTGAGCATGGGAGAGGATA
CACACTGTGCGCACTCAACATGCTAGCCCTCCTCAGCTCCCTATTTATACATAATTTATTTTTT
TACATGAAATAGAAAGGGAAATCATCAGTGAGTAGCGGGTCCTCAGGCATACTCTCTCTCTCTC
TCTCTCTCTCTCTCTCTCTTCTGTGGCTGTGTAGGTACAGAGGTTGAATTGTGTCAAGGCTAAC
ATGACAGGTTGTCACAGGTGACTCCCCTTTCTAATGCTTCCTTTCTCTTGAATATATTCTTGCC
TATTTAAAAACACAAAACAAAACAGCTCAACTTTGAACCAGGGCATTTTAACTGCCCAGCATTT
TTTAAAAGTTAGTTTTACTCTTTTCAGAAATTTAAAGTGAATTATGCAGTTGAAAAGACATACT
GTAAGGAAATGTTTTTCTTTAATAAATGGAATCATGA

hide sequence

RefSeq Acc Id:

XM_017588972 ⟹ XP_017444461

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	178,429,302 - 178,534,827 (+)	NCBI
mRatBN7.2	1	168,994,886 - 169,100,438 (+)	NCBI
Rnor_6.0	1	184,300,867 - 184,407,487 (+)	NCBI

Sequence:

show sequence

CAGAGCTTTTGGGCCTGGACCAGACTTCTGTGGACTTAGCCATCTGACACGGAGCCCAGGGTGA
GGGTGAGGTGGCGGGGTTTCTCATCAACACCCCCTGTCATTTTTGGCAAATCTGTGATTTGGAG
GGTGACTTAAGTGAGTAACTGAGTTTCCTAAGGGAAGCACCTGCAGTGGACAAACCCAGGCTTA
TTTCTGGGGCTGTTCAGCGAGGCCGCTCCCTCCTCAGGGATGTAAATTGGACCCAAATCTCTCC
TTGTTTTCTTTCAGCTCCAGAAAACTTATCGTGGCAGCATAGTCCCTTTCCCACTCCAGATGTT
GGCATGCAGGACACATGTGGGCGCCCTCGCCTGGCCGGCTCTGGAGCCTCCGGGTGATGGCCCA
ACCCAGGGGTGAGCCGGGTCTCTAATTAGACCCGACCACGTTCTCATTCCAGAGCTCCCACAGA
TGACAGCGCGCGGTCTCCACCGTGGCCAGGGGCTCCGAAATAGCCCTCGCGCCCCGGCGGAGCC
TTGCAGGCCACGGTGCCTGGCGCGGGACAAACACTTGGCAGGGCGCGCGCCGCCAGGAAAGAGT
CTGGGATTGGGGGTGGGGGAAGCCGCAGGGGCCGAAGACAACGCAGTCCTCAGCGCCCCCGCGG
CCACTTTGCTCCTAGCCTCTGGAGTTCCAGCTGCTGTGAGCTGACACCCATCGCTGGACTCTGC
ACACACTGCTCTTTGCCTTGTAAGATCAGAGGGCCAGACCGCTGTGGGCAGGCACTACTGCAGA
TTGGAATGAACATGATGGCACTACCTGGAGGCCGGCACCTGGGTTCCATTCCTCTGCAAGAGCA
GAGGCTACACTTCATGCAGGTGGACTCGGTTCAGCGCTGGATGGAGGATCTGAAGCTCATGACC
GAGTGTGAGTGCATGTGCGTCTTGCAGGCAAAGCCCATCAGCCTGGAGGAAGACACGCAGAGTG
ACCTTATCCTAGCAGGTGGTCCTGGACCAGGAGATCCTCTGCAGCTGCTCCTGAAGCGGGGCTG
GGTCATCAGCACAGAGCTTCGAAGGATCGGGCAGAAGCTGGCCCAGGACCGCTGGGCACGCGTG
CACAGCATGAGTGTGCGTCTGACGTGCCATGCACGTTCCATGGTCAGCGAGTACAGCACCATCA
GCAGGACAACCTCGCAGGAAATGGGCCAGGCAGAGAAGCTGCTCATGGAGAAATGCTCCGAGCT
CTCTGCGGTCACTGAGAGGTGCCTCCAAGTGGAAAATGAGCATGTTCTGAAGTCAATGAAGGCC
TGCGTGAGTGAGACCCTGAGCATGTTGGGCCAGCACTTTGGCCAGCTACTGGAACTGGCCCTCA
CACGGGAAGTGCAGGCACTTGTGAGAAAAATCGATACCTCAGACAATATCTACATCACGGAATC
TACCACAGGGAACCTCTTCAGCCTGACCCAGGAGGGGGCTCCTTTGTGCCGCATCATAGCCAAG
GAAGGTGGGGTTGTAGCCCTCTTCAAGGTCTGCCGGCAGGACACCTTCCGGTGTTTGTACCCCC
AGGCGCTCCGCACACTGGCCTCTATCTGCTGTGTGGAAGAGGGTGTCCATCAGCTGGAAAAGGT
GGATGGTATCCTGTGCTTGACGGACATCTTGACTGATGATAGCCACTCAGAGGCCACTCGAGCT
GAGGCTGCAGCCGTGGTAGCCCAGGTTACCTCTCCACATCTGTCTTTCACCCAGCACCTCACTA
GCTTTCTGGAGAACATGGAGGAGATTGTGACAGCCCTAATCAAACTGTGCCAAGAGGCCTCATC
AGGGGAAGTCTTCCTGCTGGCTTCTGCGGCCCTTGCCAATATCACCTTCTTCGAAAAAATGGCC
TGTGAGATGCTTCTGCAGTTGAATGCAATCCGTGTCCTTCTGGAAGCCTGTGGTGACAAACAGA
GAGTAGACACACCTTATACTCGGGACCAGATTGTGACCATCTTGGCAAACATGTCTGTGCTGGA
GCAGTGTGCCTCTGACATCATTCAGGAGAATGGTGTCCAGCTCATCATGGGCATGCTGTCGGAG
AAGCCAAGGTCTGGGACGCCTGCTGAAGTGGCAGCCTGTGAGAGAGTACAGCAGAAAGCTGCAG
TGACCCTGGCCCGCCTCTGCCGAGACCCAGATGTGGCCCGGGAGGCTGTGCGGCTCAGCTGTAT
GTCTCGCCTGATTGAGCTCTGCAGATCCCCCTCTGAGAGGAACAGCAGCGATGCCGTCCTGGTA
GCCTGCCTGTGCTCTGTGAGGAACTTGCTGCAGTTTTGGGCTGCCTTGCGTCGCTTGGCTGGGG
TCTGCCCCGAAGGCCTTCAGGACTCTGACTTCCAGCAGCTGGTCCAGCCTCGGCTTGTGGATTC
CTTCTTGCTGTGTAGCAATATGGAGGAGAGTTTTGTTTAGTGAGCATGGGAGAGGATACACACT
GTGCGCACTCAACATGCTAGCCCTCCTCAGCTCCCTATTTATACATAATTTATTTTTTTACATG
AAATAGAAAGGGAAATCATCAGTGAGTAGCGGGTCCTCAGGCATACTCTCTCTCTCTCTCTCTC
TCTCTCTCTCTCTTCTGTGGCTGTGTAGGTACAGAGGTTGAATTGTGTCAAGGCTAACATGACA
GGTTGTCACAGGTGACTCCCCTTTCTAATGCTTCCTTTCTCTTGAATATATTCTTGCCTATTTA
AAAACACAAAACAAAACAGCTCAACTTTGAACCAGGGCATTTTAACTGCCCAGCATTTTTTAAA
AGTTAGTTTTACTCTTTTCAGAAATTTAAAGTGAATTATGCAGTTGAAAAGACATACTGTAAGG
AAATGTTTTTCTTTAATAAATGGAATCATGAAAATATG

hide sequence

RefSeq Acc Id:

XM_039106438 ⟹ XP_038962366

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	178,429,301 - 178,534,827 (+)	NCBI
mRatBN7.2	1	168,994,886 - 169,100,438 (+)	NCBI

RefSeq Acc Id:

XM_039106440 ⟹ XP_038962368

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	178,429,300 - 178,534,827 (+)	NCBI
mRatBN7.2	1	168,994,884 - 169,100,438 (+)	NCBI

RefSeq Acc Id:

XM_039106441 ⟹ XP_038962369

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	178,429,811 - 178,514,579 (+)	NCBI
mRatBN7.2	1	169,012,455 - 169,080,185 (+)	NCBI

RefSeq Acc Id:

XM_063285287 ⟹ XP_063141357

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	178,427,360 - 178,534,827 (+)	NCBI

RefSeq Acc Id:

XM_063285288 ⟹ XP_063141358

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	178,442,741 - 178,534,827 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001099755	(Get FASTA)	NCBI Sequence Viewer
	XP_017444461	(Get FASTA)	NCBI Sequence Viewer
	XP_038962366	(Get FASTA)	NCBI Sequence Viewer
	XP_038962368	(Get FASTA)	NCBI Sequence Viewer
	XP_038962369	(Get FASTA)	NCBI Sequence Viewer
	XP_063141357	(Get FASTA)	NCBI Sequence Viewer
	XP_063141358	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM17756	(Get FASTA)	NCBI Sequence Viewer
	EDM17757	(Get FASTA)	NCBI Sequence Viewer
	EDM17758	(Get FASTA)	NCBI Sequence Viewer
	EDM17759	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031361
	ENSRNOP00000031361.4
	ENSRNOP00000074463
	ENSRNOP00000074463.3
	ENSRNOP00000084803.2
	ENSRNOP00000101229.1
	ENSRNOP00000101230.1
	ENSRNOP00000102436
	ENSRNOP00000102436.1

RefSeq Acc Id:

NP_001099755 ⟸ NM_001106285

- UniProtKB:

D3ZFP7 (UniProtKB/TrEMBL), A6I8C1 (UniProtKB/TrEMBL), A6I8C2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRRPPGDGDSTGEGPGNWGLWGAQESRRLCCVGPDRCGQALLQIGMNMMALPGGRHLGSIPLQE
QRLHFMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDTQSDLILAGGPGPGDPLQLLLKRG
WVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSTISRTTSQEMGQAEKLLMEKCSE
LSAVTERCLQVENEHVLKSMKACVSETLSMLGQHFGQLLELALTREVQALVRKIDTSDNIYITE
STTGNLFSLTQEGAPLCRIIAKEGGVVALFKVCRQDTFRCLYPQALRTLASICCVEEGVHQLEK
VDGILCLTDILTDDSHSEATRAEAAAVVAQVTSPHLSFTQHLTSFLENMEEIVTALIKLCQEAS
SGEVFLLASAALANITFFEKMACEMLLQLNAIRVLLEACGDKQRVDTPYTRDQIVTILANMSVL
EQCASDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLARLCRDPDVAREAVRLSC
MSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEE
SFV

hide sequence

RefSeq Acc Id:	XP_017444461 ⟸ XM_017588972
- Peptide Label:	isoform X2
- UniProtKB:	A6I8C2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNMMALPGGRHLGSIPLQEQRLHFMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDTQSDL ILAGGPGPGDPLQLLLKRGWVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSTISR TTSQEMGQAEKLLMEKCSELSAVTERCLQVENEHVLKSMKACVSETLSMLGQHFGQLLELALTR EVQALVRKIDTSDNIYITESTTGNLFSLTQEGAPLCRIIAKEGGVVALFKVCRQDTFRCLYPQA LRTLASICCVEEGVHQLEKVDGILCLTDILTDDSHSEATRAEAAAVVAQVTSPHLSFTQHLTSF LENMEEIVTALIKLCQEASSGEVFLLASAALANITFFEKMACEMLLQLNAIRVLLEACGDKQRV DTPYTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVT LARLCRDPDVAREAVRLSCMSRLIELCRSPSERNSSDAVLVACLCSVRNLLQFWAALRRLAGVC PEGLQDSDFQQLVQPRLVDSFLLCSNMEESFV hide sequence

Ensembl Acc Id:

ENSRNOP00000074463 ⟸ ENSRNOT00000078096

Ensembl Acc Id:

ENSRNOP00000031361 ⟸ ENSRNOT00000030540

RefSeq Acc Id:	XP_038962368 ⟸ XM_039106440
- Peptide Label:	isoform X4
- UniProtKB:	A6I8C2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038962366 ⟸ XM_039106438
- Peptide Label:	isoform X3
- UniProtKB:	A6I8C2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038962369 ⟸ XM_039106441
- Peptide Label:	isoform X5

Ensembl Acc Id:

ENSRNOP00000084803 ⟸ ENSRNOT00000107702

RefSeq Acc Id:	XP_063141357 ⟸ XM_063285287
- Peptide Label:	isoform X1
- UniProtKB:	A6I8C2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063141358 ⟸ XM_063285288
- Peptide Label:	isoform X2
- UniProtKB:	A6I8C2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000102436 ⟸ ENSRNOT00000169476

Ensembl Acc Id:

ENSRNOP00000101229 ⟸ ENSRNOT00000147302

Ensembl Acc Id:

ENSRNOP00000101230 ⟸ ENSRNOT00000148497

Protein Domains

Protein inscuteable homologue C-terminal Protein inscuteable homologue LGN-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZFP7-F1-model_v2	AlphaFold	D3ZFP7	1-579	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311379	AgrOrtholog
BioCyc Gene	G2FUF-57732	BioCyc
Ensembl Genes	ENSRNOG00000024712	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000030540	ENTREZGENE
	ENSRNOT00000030540.7	UniProtKB/TrEMBL
	ENSRNOT00000078096	ENTREZGENE
	ENSRNOT00000078096.3	UniProtKB/TrEMBL
	ENSRNOT00000107702.2	UniProtKB/TrEMBL
	ENSRNOT00000147302.1	UniProtKB/TrEMBL
	ENSRNOT00000148497.1	UniProtKB/TrEMBL
	ENSRNOT00000169476	ENTREZGENE
	ENSRNOT00000169476.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.10.10	UniProtKB/TrEMBL
	6.20.200.10	UniProtKB/TrEMBL
InterPro	ARM-like	UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/TrEMBL
	Armadillo	UniProtKB/TrEMBL
	Insc_C	UniProtKB/TrEMBL
	INSC_LBD	UniProtKB/TrEMBL
	INSC_LBD_sf	UniProtKB/TrEMBL
	Inscuteable	UniProtKB/TrEMBL
KEGG Report	rno:293166	UniProtKB/TrEMBL
NCBI Gene	293166	ENTREZGENE
PANTHER	PROTEIN INSCUTEABLE HOMOLOG	UniProtKB/TrEMBL
	PTHR21386	UniProtKB/TrEMBL
Pfam	Insc_C	UniProtKB/TrEMBL
	INSC_LBD	UniProtKB/TrEMBL
PhenoGen	Insc	PhenoGen
RatGTEx	ENSRNOG00000024712	RatGTEx
SMART	ARM	UniProtKB/TrEMBL
Superfamily-SCOP	ARM-type_fold	UniProtKB/TrEMBL
UniProt	A0A0G2K843_RAT	UniProtKB/TrEMBL
	A0A8I6A211_RAT	UniProtKB/TrEMBL
	A0ABK0L032_RAT	UniProtKB/TrEMBL
	A0ABK0LAI4_RAT	UniProtKB/TrEMBL
	A0ABK0LIR5_RAT	UniProtKB/TrEMBL
	A6I8C1	ENTREZGENE, UniProtKB/TrEMBL
	A6I8C2	ENTREZGENE, UniProtKB/TrEMBL
	D3ZFP7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-06-21	Insc	INSC, spindle orientation adaptor protein	Insc	inscuteable homolog (Drosophila)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-27	Insc	inscuteable homolog (Drosophila)	RGD1311379_predicted	hypothetical LOC293166 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1311379_predicted	hypothetical LOC293166 (predicted)	LOC293166_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC293166_predicted	hypothetical LOC293166 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message