INSC (INSC spindle orientation adaptor protein)

Gene: INSC (INSC spindle orientation adaptor protein) Sus scrofa

Analyze

Symbol:

INSC

Name:

INSC spindle orientation adaptor protein

RGD ID:

14105706

Description:

ENCODES a protein that exhibits cytoskeletal anchor activity (inferred); protein domain specific binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN establishment of mitotic spindle orientation (ortholog); lung epithelial cell differentiation (ortholog); ASSOCIATED WITH intellectual disability (ortholog); FOUND IN apical part of cell (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

inscuteable homolog; protein inscuteable homolog

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	43,843,568 - 44,015,191 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	43,843,539 - 44,015,266 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	47,050,716 - 47,221,492 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apical protein localization (IBA,IEA)

asymmetric cell division (IEA)

establishment of mitotic spindle orientation (IBA,IEA,ISO)

lung epithelial cell differentiation (ISO)

regulation of asymmetric cell division (IBA,IEA)

regulation of protein stability (IEA)

Cellular Component

apical cortex (IBA,IEA)

apical part of cell (ISO)

cell cortex (IEA)

plasma membrane (IEA)

protein-containing complex (IEA)

Molecular Function

cytoskeletal anchor activity (IBA,IEA)

protein binding (ISO)

protein domain specific binding (IEA)

protein-macromolecule adaptor activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

INSC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	43,843,568 - 44,015,191 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	43,843,539 - 44,015,266 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	47,050,716 - 47,221,492 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

INSC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	15,111,416 - 15,269,676 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	15,112,424 - 15,247,208 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	15,133,970 - 15,268,754 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	15,090,546 - 15,225,330 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	15,261,213 - 15,395,928 (+)	NCBI		Celera
Cytogenetic Map	11	p15.2	NCBI
HuRef	11	14,817,520 - 14,952,207 (+)	NCBI		HuRef
CHM1_1	11	15,132,981 - 15,268,351 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	15,207,776 - 15,366,083 (+)	NCBI		T2T-CHM13v2.0

Insc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	114,342,931 - 114,449,615 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	114,342,929 - 114,449,618 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	114,743,688 - 114,850,380 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	114,743,694 - 114,850,383 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	121,889,280 - 121,993,894 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	114,583,211 - 114,641,363 (+)	NCBI		MGSCv36	mm8
Celera	7	114,699,353 - 114,804,111 (+)	NCBI		Celera
Cytogenetic Map	7	F1	NCBI
cM Map	7	60.23	NCBI

Insc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	178,427,360 - 178,534,827 (+)	NCBI		GRCr8
mRatBN7.2	1	168,993,032 - 169,100,438 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	168,993,032 - 169,100,433 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	177,313,540 - 177,420,920 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	184,499,609 - 184,606,997 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	177,206,376 - 177,313,740 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	184,299,200 - 184,407,487 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	184,299,250 - 184,407,480 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	191,272,625 - 191,380,862 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	172,804,412 - 172,913,667 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	172,938,861 - 173,045,793 (+)	NCBI
Celera	1	166,826,157 - 166,933,448 (+)	NCBI		Celera
Cytogenetic Map	1	q34	NCBI

Insc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	30,156,327 - 30,283,146 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	30,181,402 - 30,282,279 (+)	NCBI	ChiLan1.0	ChiLan1.0

INSC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	17,481,904 - 17,613,908 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	17,407,636 - 17,574,975 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	15,203,357 - 15,335,341 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	14,892,357 - 15,024,344 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	14,892,357 - 15,024,344 (+)	Ensembl	panpan1.1		panPan2

INSC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	37,942,334 - 38,063,690 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	37,942,294 - 38,063,146 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	37,447,110 - 37,565,970 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	39,072,642 - 39,160,340 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	39,039,305 - 39,160,039 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	38,058,728 - 38,177,862 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	38,263,829 - 38,382,671 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	38,551,635 - 38,670,419 (+)	NCBI		UU_Cfam_GSD_1.0

Insc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	47,528,402 - 47,647,823 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936528	3,562,854 - 3,681,669 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936528	3,562,426 - 3,681,733 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

INSC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	49,674,580 - 49,807,746 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	49,675,737 - 49,807,208 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	147,170,322 - 147,302,423 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Insc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624766	6,884,824 - 7,016,392 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624766	6,935,814 - 7,016,335 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in INSC
5910 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	musculoskeletal system	nervous system	reproductive system
High
Medium
Low	2	2		13	1
Below cutoff	8		1	6	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021083296	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021083297	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU463089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSSCT00000014620 ⟹ ENSSSCP00000014225

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	43,843,568 - 44,012,662 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000076769 ⟹ ENSSSCP00000070185

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	43,843,561 - 44,012,662 (-)	Ensembl

RefSeq Acc Id:

ENSSSCT00000085528 ⟹ ENSSSCP00000061989

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	2	43,843,568 - 44,015,191 (-)	Ensembl

RefSeq Acc Id:

XM_021083296 ⟹ XP_020938955

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	2	43,843,539 - 44,012,797 (-)	NCBI

Sequence:

show sequence

CTTGGCCCGGAGCGCGCTGTTGCTGGCGGGCGGGGGCAGAGCGGGGCGGAGGCGCGGGGCAGCG
GGCGGCCCTCGGGCTGGGCCGGCCGGGCGGGTCACTTGCTTACAGCCTCTGGCGCCCCAGCTGC
GCCTGCCACCGCCGGCCTGGCCGCTGCACGCAGCTGCTCGCAGGCTCTCTCGCTCCGTCAGAGG
CCCCAACCGCTGCGGGCAGGCTTTGCTGCAGATCGGCGTCAACCTGATGGCGCTGCCGGGAGGC
CGACACCTGGACTGCATCCCCCTGCAGGGTCAGCGGCTGCACCTGATGCAGGTGGATTCGGTCC
AGCGCTGGATGGAGGACCTGAAGCTCATGACAGAGTGTGAGTGCATGTGTGTCCTGCAGGCGAA
GCCCATCAGCCTCGAGGAGGATGCACAGGGTGACCTCATCTTGGCAGGTGGCCCAGGCCCTGGA
GACCCCCTGCAGCTGCTGCTCAAACGTGGCTGGGTCATCAGCACTGAGCTGCGCAGGATCGGCC
AGAAGCTGGCCCAGGACCGCTGGGCACGTGTCCACAGCATGAGTGTGCGGCTGACCTGCCACGC
CCGCTCCATGGTCAGCGAGTACAGCGCTGTTAGCAGGAGCTCCTCGCAGGAGATGGGCCAGATT
GAGAAGCTGCTAATGGAGAAGTGCTCAGAGCTGTCGGCAGTCACAGAGAGGTGCCTCCAGGTGG
AGAACGAGCACGTCCTGAAGTCAATGAAGGCCTGTGTGAGTGAGACCCTGAGCATGCTGGGCCA
GCACTTTGGGCAGCTCCTGGAGCTGGCCCTGACCCGGGAAGTGCAGGCCCTGGTGAGAAAAATC
GATGCCTCTGACAATGTCTACACCACAGAATCCACCACAGGAAACCTGTTCAGCCTGACCCAAG
AGGGGGCTCCCTTGTGCCGCATCATAGCCAAGGAGGGTGGGGTCGTAGCGCTCTTCAAGGTCTG
CCGGCAGGACAGCTTCCGGTGCCTGTACCCCCAGGCGCTCCGCACGCTGGCCTCCATCTGCTGC
GTGGAGGAGGGTGTCCACCAGCTGGAGAAGGTGGACGGCGTTCTGTGCTTGGCGGATATCCTGA
CCGACGACAGTCACTCAGAGGCCACGCGGGCTGAGGCTGCGGCCGTGGTCGCCCAGGTCACCTC
CCCACACCTGCCCTTCACCCAGCATCTCAGCAGCTTCCTGGAGAGCATGGAGGAGATCGTGACA
GCCCTCGTTAAACTGTGCCAAGAGGCCTCATCTGGGGAAGTCTTCCTGCTGGCCTCTGCGGCCC
TTGCCAACATCACCTTCTTGGACACGATGGCCTGTGAGATGCTCCTTCAGCTGAATGCCATCCG
CGTCCTCCTGGAGGCCTGCAGTGACAAGCAGAGAGTAGATACGCCTTATACCCGGGACCAGATT
GTGACCATCTTGGCAAACATGTCTGTCCTGGAGCAGTGCGCCTCTGACATCATTCAGGAGAACG
GGGTCCAGCTGATCATGGGCATGCTGTCTGAGAAGCCAAGGTCTGGGACCCCTGCCGAGGTGGC
AGCCTGTGAGCGAGTCCAGCAGAAGGCTGCAGTGACCCTGGCCCGTCTCAGCCGAGATCCAGAG
GTGGCACGAGAGGCTGTGCGGCTGAGCTGCATGTCCCGCCTCATCGAACTCTGCCGCTCGCCCT
CCGAGAGGAACAGCAGTGATGCCGTGCTGGTGGCCTGCCTGGCTGCCCTGCGTAGATTGGCTGG
AGTCTGCCCTGAAGGCCTCCAGGACTCTGACTTCCAGCAGCTGGTCCAGCCTCGGCTTGTGGAC
TCTTTCTTACTCTGCAGCAACATGGAGGAGAGTTTTGTGTAGCAAGTGGGGGAGAAGAAAAGAC
CTCATTTTCAAGGCCCCTCTGAGTACATGCCTGTGAACATAACTGACTACACACCAGTCCCCTC
ACCTCTTTATTTATACTTAATTTATTTTTTATGTGAAATGAACAGAGGGCTAAATATTCTAGCA
ATATCATGAGGAAGTGTGCGGTCCTTAGGAGTCTTTTTCATTTTTATTTTTTGACTTCTGTGAC
TTTTCAGTTGCAGATGTTGAAATGCATAATGGCTAATATGACAGATTGTCATGGGTGATTTCAC
TTCCTCTTTCATTCTCTACTCTCAATATATAATCTTGTCTCATTTTTTAAAAAAAATTTTAGCT
GTCCAGCAGTCTTTTTTTAAAAGTTGGATTTGCTCTAAGAGATTTTAAATGAATTTCATAGTTG
GACAAAATATACTGGAAGGAAATTCTAGCTTTATTCTTTAATAAAAGAAAACATACAAAATGTG
TCTTAATTTTCTGATTAAA

hide sequence

RefSeq Acc Id:

XM_021083297 ⟹ XP_020938956

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	2	43,843,539 - 44,015,266 (-)	NCBI

Sequence:

show sequence

CGCAGGCCTTGCTGGGGCCATGGCCCAGGATGGGCAAGGAGATAGGAGTTGCCTGCAGGGGCTT
CTGTAAGGAGACTTGGATTTGCTGCAGCCATGAGGAGGCCCCCTGGGAATGGAGAGATGGCCAG
CAAGGGTATAAGCGGCTGGGGCCTATGGGGCCGACAAGAGCCCAGGAGGCTGTGCTGTACTGGC
CCCAACCGCTGCGGGCAGGCTTTGCTGCAGATCGGCGTCAACCTGATGGCGCTGCCGGGAGGCC
GACACCTGGACTGCATCCCCCTGCAGGGTCAGCGGCTGCACCTGATGCAGGTGGATTCGGTCCA
GCGCTGGATGGAGGACCTGAAGCTCATGACAGAGTGTGAGTGCATGTGTGTCCTGCAGGCGAAG
CCCATCAGCCTCGAGGAGGATGCACAGGGTGACCTCATCTTGGCAGGTGGCCCAGGCCCTGGAG
ACCCCCTGCAGCTGCTGCTCAAACGTGGCTGGGTCATCAGCACTGAGCTGCGCAGGATCGGCCA
GAAGCTGGCCCAGGACCGCTGGGCACGTGTCCACAGCATGAGTGTGCGGCTGACCTGCCACGCC
CGCTCCATGGTCAGCGAGTACAGCGCTGTTAGCAGGAGCTCCTCGCAGGAGATGGGCCAGATTG
AGAAGCTGCTAATGGAGAAGTGCTCAGAGCTGTCGGCAGTCACAGAGAGGTGCCTCCAGGTGGA
GAACGAGCACGTCCTGAAGTCAATGAAGGCCTGTGTGAGTGAGACCCTGAGCATGCTGGGCCAG
CACTTTGGGCAGCTCCTGGAGCTGGCCCTGACCCGGGAAGTGCAGGCCCTGGTGAGAAAAATCG
ATGCCTCTGACAATGTCTACACCACAGAATCCACCACAGGAAACCTGTTCAGCCTGACCCAAGA
GGGGGCTCCCTTGTGCCGCATCATAGCCAAGGAGGGTGGGGTCGTAGCGCTCTTCAAGGTCTGC
CGGCAGGACAGCTTCCGGTGCCTGTACCCCCAGGCGCTCCGCACGCTGGCCTCCATCTGCTGCG
TGGAGGAGGGTGTCCACCAGCTGGAGAAGGTGGACGGCGTTCTGTGCTTGGCGGATATCCTGAC
CGACGACAGTCACTCAGAGGCCACGCGGGCTGAGGCTGCGGCCGTGGTCGCCCAGGTCACCTCC
CCACACCTGCCCTTCACCCAGCATCTCAGCAGCTTCCTGGAGAGCATGGAGGAGATCGTGACAG
CCCTCGTTAAACTGTGCCAAGAGGCCTCATCTGGGGAAGTCTTCCTGCTGGCCTCTGCGGCCCT
TGCCAACATCACCTTCTTGGACACGATGGCCTGTGAGATGCTCCTTCAGCTGAATGCCATCCGC
GTCCTCCTGGAGGCCTGCAGTGACAAGCAGAGAGTAGATACGCCTTATACCCGGGACCAGATTG
TGACCATCTTGGCAAACATGTCTGTCCTGGAGCAGTGCGCCTCTGACATCATTCAGGAGAACGG
GGTCCAGCTGATCATGGGCATGCTGTCTGAGAAGCCAAGGTCTGGGACCCCTGCCGAGGTGGCA
GCCTGTGAGCGAGTCCAGCAGAAGGCTGCAGTGACCCTGGCCCGTCTCAGCCGAGATCCAGAGG
TGGCACGAGAGGCTGTGCGGCTGAGCTGCATGTCCCGCCTCATCGAACTCTGCCGCTCGCCCTC
CGAGAGGAACAGCAGTGATGCCGTGCTGGTGGCCTGCCTGGCTGCCCTGCGTAGATTGGCTGGA
GTCTGCCCTGAAGGCCTCCAGGACTCTGACTTCCAGCAGCTGGTCCAGCCTCGGCTTGTGGACT
CTTTCTTACTCTGCAGCAACATGGAGGAGAGTTTTGTGTAGCAAGTGGGGGAGAAGAAAAGACC
TCATTTTCAAGGCCCCTCTGAGTACATGCCTGTGAACATAACTGACTACACACCAGTCCCCTCA
CCTCTTTATTTATACTTAATTTATTTTTTATGTGAAATGAACAGAGGGCTAAATATTCTAGCAA
TATCATGAGGAAGTGTGCGGTCCTTAGGAGTCTTTTTCATTTTTATTTTTTGACTTCTGTGACT
TTTCAGTTGCAGATGTTGAAATGCATAATGGCTAATATGACAGATTGTCATGGGTGATTTCACT
TCCTCTTTCATTCTCTACTCTCAATATATAATCTTGTCTCATTTTTTAAAAAAAATTTTAGCTG
TCCAGCAGTCTTTTTTTAAAAGTTGGATTTGCTCTAAGAGATTTTAAATGAATTTCATAGTTGG
ACAAAATATACTGGAAGGAAATTCTAGCTTTATTCTTTAATAAAAGAAAACATACAAAATGTGT
CTTAATTTTCTGATTAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_020938955	(Get FASTA)	NCBI Sequence Viewer
	XP_020938956	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000014225
	ENSSSCP00000014225.5
	ENSSSCP00000061989
	ENSSSCP00000061989.2
	ENSSSCP00025042648.1
	ENSSSCP00035040266.1
	ENSSSCP00050003467.1

RefSeq Acc Id:	XP_020938956 ⟸ XM_021083297
- Peptide Label:	isoform X2
- UniProtKB:	A0A5G2QIZ0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRRPPGNGEMASKGISGWGLWGRQEPRRLCCTGPNRCGQALLQIGVNLMALPGGRHLDCIPLQG QRLHLMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDAQGDLILAGGPGPGDPLQLLLKRG WVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSAVSRSSSQEMGQIEKLLMEKCSE LSAVTERCLQVENEHVLKSMKACVSETLSMLGQHFGQLLELALTREVQALVRKIDASDNVYTTE STTGNLFSLTQEGAPLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRTLASICCVEEGVHQLEK VDGVLCLADILTDDSHSEATRAEAAAVVAQVTSPHLPFTQHLSSFLESMEEIVTALVKLCQEAS SGEVFLLASAALANITFLDTMACEMLLQLNAIRVLLEACSDKQRVDTPYTRDQIVTILANMSVL EQCASDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLARLSRDPEVAREAVRLSC MSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLVQPRLVDSFLLCSNMEE SFV hide sequence

RefSeq Acc Id:	XP_020938955 ⟸ XM_021083296
- Peptide Label:	isoform X1
- UniProtKB:	A0A8D0TKZ1 (UniProtKB/TrEMBL), A0A480JGP6 (UniProtKB/TrEMBL), A0A480EXJ7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALPGGRHLDCIPLQGQRLHLMQVDSVQRWMEDLKLMTECECMCVLQAKPISLEEDAQGDLILA GGPGPGDPLQLLLKRGWVISTELRRIGQKLAQDRWARVHSMSVRLTCHARSMVSEYSAVSRSSS QEMGQIEKLLMEKCSELSAVTERCLQVENEHVLKSMKACVSETLSMLGQHFGQLLELALTREVQ ALVRKIDASDNVYTTESTTGNLFSLTQEGAPLCRIIAKEGGVVALFKVCRQDSFRCLYPQALRT LASICCVEEGVHQLEKVDGVLCLADILTDDSHSEATRAEAAAVVAQVTSPHLPFTQHLSSFLES MEEIVTALVKLCQEASSGEVFLLASAALANITFLDTMACEMLLQLNAIRVLLEACSDKQRVDTP YTRDQIVTILANMSVLEQCASDIIQENGVQLIMGMLSEKPRSGTPAEVAACERVQQKAAVTLAR LSRDPEVAREAVRLSCMSRLIELCRSPSERNSSDAVLVACLAALRRLAGVCPEGLQDSDFQQLV QPRLVDSFLLCSNMEESFV hide sequence

RefSeq Acc Id:

ENSSSCP00000070185 ⟸ ENSSSCT00000076769

RefSeq Acc Id:

ENSSSCP00000061989 ⟸ ENSSSCT00000085528

RefSeq Acc Id:

ENSSSCP00000014225 ⟸ ENSSSCT00000014620

Protein Domains

Protein inscuteable homologue C-terminal Protein inscuteable homologue LGN-binding

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000013385	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00025070704	UniProtKB/TrEMBL
	ENSSSCG00035070787	UniProtKB/TrEMBL
	ENSSSCG00050005990	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000014620	ENTREZGENE
	ENSSSCT00000014620.5	UniProtKB/TrEMBL
	ENSSSCT00000085528	ENTREZGENE
	ENSSSCT00000085528.2	UniProtKB/TrEMBL
	ENSSSCT00025097140.1	UniProtKB/TrEMBL
	ENSSSCT00035095686.1	UniProtKB/TrEMBL
	ENSSSCT00050008154.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.10.10	UniProtKB/TrEMBL
	6.20.200.10	UniProtKB/TrEMBL
InterPro	ARM-like	UniProtKB/TrEMBL
	ARM-type_fold	UniProtKB/TrEMBL
	Armadillo	UniProtKB/TrEMBL
	Insc_C	UniProtKB/TrEMBL
	INSC_LBD	UniProtKB/TrEMBL
	INSC_LBD_sf	UniProtKB/TrEMBL
	Inscuteable	UniProtKB/TrEMBL
NCBI Gene	INSC	ENTREZGENE
PANTHER	PROTEIN INSCUTEABLE HOMOLOG	UniProtKB/TrEMBL
	PTHR21386	UniProtKB/TrEMBL
Pfam	Insc_C	UniProtKB/TrEMBL
	INSC_LBD	UniProtKB/TrEMBL
SMART	ARM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48371	UniProtKB/TrEMBL
UniProt	A0A480EXJ7	ENTREZGENE, UniProtKB/TrEMBL
	A0A480JGP6	ENTREZGENE, UniProtKB/TrEMBL
	A0A5G2QIZ0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0TKZ1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1B042_PIG	UniProtKB/TrEMBL
	F1S991_PIG	UniProtKB/TrEMBL
VGNC ID	VGNC:89149	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar